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Apellis Pharmaceuticals, Inc.

APLSDelisted
Industry
Pharmaceutical Preparations
SEC CIK
0001492422

Apellis Pharmaceuticals, Inc. was delisted in 2026; its insiders filed their last Form 4 on May 14, 2026; 324 institutions reported holding it in 13F filings for Q1 2026, worth $5.56B in total; Soros Fund Management was the only superinvestor holding it.

13F holders, Q1 2026

Institutional positions in Apellis Pharmaceuticals, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

APLS is no longer listed, so this page shows Q1 2026. 13F filings for later quarters list far fewer holders.

Institutional holders
324
+49 vs. Q4 2025
Shares held
140.4M
+25.8M (+22.6%) vs. Q4 2025
Total value
$5.56B
+$2.69B (+93.5%) vs. Q4 2025
New holders
127
91 more added
Sold out
78
72 more reduced

5 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting APLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 324 institutions
Q1 2021: 175 institutionsQ2 2021: 205 institutionsQ3 2021: 181 institutionsQ4 2021: 187 institutionsQ1 2022: 212 institutionsQ2 2022: 212 institutionsQ3 2022: 250 institutionsQ4 2022: 244 institutionsQ1 2023: 282 institutionsQ2 2023: 317 institutionsQ3 2023: 256 institutionsQ4 2023: 284 institutionsQ1 2024: 302 institutionsQ2 2024: 263 institutionsQ3 2024: 265 institutionsQ4 2024: 260 institutionsQ1 2025: 255 institutionsQ2 2025: 247 institutionsQ3 2025: 273 institutionsQ4 2025: 280 institutionsQ1 2026: 324 institutionsQ2 2026: 1 institution
Value heldQ1 2026: $5.56B
Q1 2021: $2.80BQ2 2021: $4.13BQ3 2021: $2.29BQ4 2021: $3.91BQ1 2022: $4.62BQ2 2022: $4.15BQ3 2022: $6.67BQ4 2022: $5.26BQ1 2023: $7.49BQ2 2023: $9.81BQ3 2023: $4.34BQ4 2023: $7.16BQ1 2024: $6.97BQ2 2024: $4.56BQ3 2024: $3.52BQ4 2024: $4.05BQ1 2025: $2.80BQ2 2025: $2.29BQ3 2025: $2.77BQ4 2025: $3.17BQ1 2026: $5.56BQ2 2026: $10.2K
Institutions holding APLS and their total value by quarter
QuarterHoldersValue
Q2 20261$10.2K
Q1 2026324$5.56B
Q4 2025280$3.17B
Q3 2025273$2.77B
Q2 2025247$2.29B
Q1 2025255$2.80B
Q4 2024260$4.05B
Q3 2024265$3.52B
Q2 2024263$4.56B
Q1 2024302$6.97B
Q4 2023284$7.16B
Q3 2023256$4.34B
Q2 2023317$9.81B
Q1 2023282$7.49B
Q4 2022244$5.26B
Q3 2022250$6.67B
Q2 2022212$4.15B
Q1 2022212$4.62B
Q4 2021187$3.91B
Q3 2021181$2.29B
Q2 2021205$4.13B
Q1 2021175$2.80B

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Apellis Pharmaceuticals, Inc.; share changes are against Q4 2025.

Institutions holding APLS in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Hudson Bay Capital Management LP1,190,416$47.9M0.29%+10,588+0.9%Added
Bank of America Corp1,190,864$47.9M0.00%+234,091+24.5%Added
Healthcare of Ontario Pension Plan Trust Fund1,202,100$48.4M0.08%+1,202,100New
Toronto Dominion Bank1,236,436$49.7M0.10%+1,236,436New
TIG Advisors, LLC1,252,986$50.4M2.41%+1,252,986New
Glazer Capital, LLC1,294,196$52.1M1.11%+1,294,196New
Dimensional Fund Advisors LP1,338,995$53.7M0.01%+1,158,070+640.1%Added
Balyasny Asset Management LLC1,917,501$77.1M0.15%+1,852,368+2,844.0%Added
Goldman Sachs Group Inc1,980,144$79.7M0.01%+1,790,939+946.6%Added
Geode Capital Management, LLC2,075,075$83.5M0.01%+49,406+2.4%Added
Millennium Management LLC2,256,802$90.8M0.07%+1,310,343+138.4%Added
Suvretta Capital Management, LLC3,518,471$141.5M3.84%−620,955−15.0%Reduced
HBK Investments L P3,550,000$142.8M1.80%+3,550,000New
RTW Investments, LP3,685,045$148.2M1.48%−3,981,719−51.9%Reduced
Point72 Asset Management, L.P.4,183,918$168.3M0.29%+3,586,246+600.0%Added
Deep Track Capital, LP4,532,374$182.3M3.76%−3,217,626−41.5%Reduced
Vanguard Capital Management LLC4,768,944$191.9M0.00%+4,768,944New
Pentwater Capital Management LP5,250,000$211.2M1.50%+5,250,000New
Vanguard Portfolio Management LLC5,404,559$217.4M0.01%+5,404,559New
UBS Group AG6,206,681$249.7M0.04%+2,020,459+48.3%Added
State Street Corp6,844,990$275.4M0.01%+2,231,544+48.4%Added
Morgan Stanley10,042,399$404.0M0.02%+869,395+9.5%Added
Avoro Capital Advisors LLC12,222,222$491.7M4.84%00.0%Unchanged
BlackRock, Inc.13,536,964$544.6M0.01%+7,276,851+116.2%Added
Massmutual Trust Co FSB0$00.00%−106−100.0%Sold out
Polar Capital Holdings Plc0$00.00%−3,706,510−100.0%Sold out
Siren, L.L.C.0$00.00%−2,578,396−100.0%Sold out
OrbiMed Advisors LLC0$00.00%−2,429,868−100.0%Sold out
Jennison Associates LLC0$00.00%−1,504,299−100.0%Sold out
Bank of Nova Scotia0$00.00%−1,070,141−100.0%Sold out
Simplify Asset Management Inc.0$00.00%−538,008−100.0%Sold out
Voloridge Investment Management, LLC0$00.00%−461,186−100.0%Sold out
Rhenman & Partners Asset Management AB0$00.00%−374,450−100.0%Sold out
Schroder Investment Management Group0$00.00%−329,134−100.0%Sold out
J. Goldman & Co LP0$00.00%−285,992−100.0%Sold out
Natixis0$00.00%−257,268−100.0%Sold out
Caption Management, LLC0$00.00%−254,563−100.0%Sold out
Integral Health Asset Management, LLC0$00.00%−200,000−100.0%Sold out
HRT Financial LP0$00.00%−192,488−100.0%Sold out
Apis Capital Advisors, LLC0$00.00%−192,000−100.0%Sold out
Silvercrest Asset Management Group LLC0$00.00%−190,759−100.0%Sold out
California Public Employees Retirement System0$00.00%−186,328−100.0%Sold out
HighVista Strategies LLC0$00.00%−150,776−100.0%Sold out
DekaBank Deutsche Girozentrale0$00.00%−55,000−100.0%Sold out
ING Groep NV0$00.00%−139,000−100.0%Sold out
Two Sigma Advisers, LP0$00.00%−110,900−100.0%Sold out
Algert Global LLC0$00.00%−109,733−100.0%Sold out
Edgestream Partners, L.P.0$00.00%−97,443−100.0%Sold out
Coppell Advisory Solutions LLC0$00.00%−77,390−100.0%Sold out
Ikarian Capital, LLC0$00.00%−71,747−100.0%Sold out
Jane Street Group, LLC0$00.00%−50,114−100.0%Sold out
Ishara Investments LP0$00.00%−50,000−100.0%Sold out
Panagora Asset Management Inc0$00.00%−42,134−100.0%Sold out
Vontobel Holding Ltd.0$00.00%−34,039−100.0%Sold out
Dark Forest Capital Management LP0$00.00%−31,091−100.0%Sold out
Ieq Capital, LLC0$00.00%−25,500−100.0%Sold out
Quadrature Capital Ltd0$00.00%−24,075−100.0%Sold out
Cerity Partners LLC0$00.00%−23,971−100.0%Sold out
Entropy Technologies, LP0$00.00%−23,128−100.0%Sold out
PSP Research LLC0$00.00%−21,866−100.0%Sold out
Diversified Trust Co0$00.00%−18,942−100.0%Sold out
Qube Research & Technologies Ltd0$00.00%−18,843−100.0%Sold out
Advent Capital Management0$00.00%−18,000−100.0%Sold out
Allianz Asset Management GmbH0$00.00%−17,000−100.0%Sold out
Brevan Howard Capital Management LP0$00.00%−16,117−100.0%Sold out
Maven Securities LTD0$00.00%−15,000−100.0%Sold out
GWM Advisors LLC0$00.00%−14,570−100.0%Sold out
Nomura Holdings Inc0$00.00%−14,200−100.0%Sold out
Pallas Capital Advisors LLC0$00.00%−13,885−100.0%Sold out
Twinbeech Capital LP0$00.00%−13,152−100.0%Sold out
Freestone Grove Partners LP0$00.00%−12,537−100.0%Sold out
Quest Partners LLC0$00.00%−11,741−100.0%Sold out
Bridgefront Capital, LLC0$00.00%−11,326−100.0%Sold out
Arrowpoint Investment Partners (Singapore) Pte. Ltd.0$00.00%−10,806−100.0%Sold out
Perbak Capital Partners LLP0$00.00%−10,217−100.0%Sold out
Graham Capital Management, L.P.0$00.00%−9,302−100.0%Sold out
Mirabella Financial Services LLP0$00.00%−9,078−100.0%Sold out
Quantitative Investment Management, LLC0$00.00%−8,611−100.0%Sold out
Quarry LP0$00.00%−5,000−100.0%Sold out
Bellevue Group AG0$00.00%−4,210−100.0%Sold out
Atlantic Private Wealth, LLC0$00.00%−1,000−100.0%Sold out
EFG International AG0$00.00%−788−100.0%Sold out
Aster Capital Management (DIFC) Ltd0$00.00%−643−100.0%Sold out
Daiwa Securities Group Inc.0$00.00%−369−100.0%Sold out
Bessemer Group Inc0$00.00%−205−100.0%Sold out
Torren Management, LLC0$00.00%−189−100.0%Sold out
ZRC Wealth Management, LLC0$00.00%−151−100.0%Sold out
Crewe Advisors LLC0$00.00%−88−100.0%Sold out
SRS Capital Advisors, Inc.0$00.00%−46−100.0%Sold out
Sunbelt Securities, Inc.0$00.00%−39−100.0%Sold out
SageView Advisory Group, LLC0$00.00%−35−100.0%Sold out
Basecamp Wealth Advisors LLC0$00.00%−31−100.0%Sold out
Turning Point Benefit Group, Inc.0$00.00%−27−100.0%Sold out
Bare Financial Services, Inc0$00.00%−25−100.0%Sold out
United Financial Planning Group LLC0$00.00%−24−100.0%Sold out
Greenline Wealth Management LLC0$00.00%−21−100.0%Sold out
South State Corp.0$00.00%−15−100.0%Sold out
Ronald Blue Trust, Inc.0$00.00%−14−100.0%Sold out
Clearstead Advisors, LLC0$00.00%−13−100.0%Sold out
Assetmark, Inc0$00.00%−10−100.0%Sold out