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Apellis Pharmaceuticals, Inc.

APLSDelisted May 14, 2026
Industry
Pharmaceutical Preparations
SEC CIK
0001492422

Apellis Pharmaceuticals, Inc. was delisted on May 14, 2026; its insiders filed their last Form 4 on May 14, 2026; 324 institutions reported holding it in 13F filings for Q1 2026, worth $5.56B in total; Soros Fund Management was the only superinvestor holding it.

13F holders, Q2 2025

Institutional positions in Apellis Pharmaceuticals, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
247
−6 vs. Q1 2025
Shares held
131.5M
+3.54M (+2.8%) vs. Q1 2025
Total value
$2.28B
−$523.6M (−18.7%) vs. Q1 2025
New holders
43
108 more added
Sold out
49
68 more reduced

2 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting APLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 247 institutions
Q1 2021: 175 institutionsQ2 2021: 205 institutionsQ3 2021: 181 institutionsQ4 2021: 187 institutionsQ1 2022: 212 institutionsQ2 2022: 212 institutionsQ3 2022: 250 institutionsQ4 2022: 244 institutionsQ1 2023: 282 institutionsQ2 2023: 317 institutionsQ3 2023: 256 institutionsQ4 2023: 284 institutionsQ1 2024: 302 institutionsQ2 2024: 263 institutionsQ3 2024: 265 institutionsQ4 2024: 260 institutionsQ1 2025: 255 institutionsQ2 2025: 247 institutionsQ3 2025: 273 institutionsQ4 2025: 280 institutionsQ1 2026: 324 institutionsQ2 2026: 1 institution
Value heldQ2 2025: $2.28B
Q1 2021: $2.80BQ2 2021: $4.08BQ3 2021: $2.29BQ4 2021: $3.83BQ1 2022: $4.62BQ2 2022: $4.15BQ3 2022: $6.66BQ4 2022: $5.20BQ1 2023: $7.28BQ2 2023: $9.71BQ3 2023: $4.34BQ4 2023: $6.82BQ1 2024: $6.65BQ2 2024: $4.43BQ3 2024: $3.41BQ4 2024: $4.04BQ1 2025: $2.80BQ2 2025: $2.28BQ3 2025: $2.77BQ4 2025: $3.17BQ1 2026: $5.56BQ2 2026: $10.2K
Institutions holding APLS and their total value by quarter
QuarterHoldersValue
Q2 20261$10.2K
Q1 2026324$5.56B
Q4 2025280$3.17B
Q3 2025273$2.77B
Q2 2025247$2.28B
Q1 2025255$2.80B
Q4 2024260$4.04B
Q3 2024265$3.41B
Q2 2024263$4.43B
Q1 2024302$6.65B
Q4 2023284$6.82B
Q3 2023256$4.34B
Q2 2023317$9.71B
Q1 2023282$7.28B
Q4 2022244$5.20B
Q3 2022250$6.66B
Q2 2022212$4.15B
Q1 2022212$4.62B
Q4 2021187$3.83B
Q3 2021181$2.29B
Q2 2021205$4.08B
Q1 2021175$2.80B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Apellis Pharmaceuticals, Inc.; share changes are against Q1 2025.

Institutions holding APLS in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Squarepoint Ops LLC329,392$5.70M0.01%−113,401−25.6%Reduced
Canada Pension Plan Investment Board336,800$5.83M0.00%−711,900−67.9%Reduced
Ieq Capital, LLC346,923$6.01M0.04%+55,065+18.9%Added
Pictet Asset Management Holding SA348,349$6.07M0.01%+33,507+10.6%Added
Two Sigma Investments, LP406,913$7.04M0.01%+144,009+54.8%Added
683 Capital Management, LLC410,000$7.10M0.72%+77,000+23.1%Added
Citadel Advisors LLC442,560$7.66M0.01%+218,464+97.5%Added
Voloridge Investment Management, LLC468,710$8.11M0.03%+214,920+84.7%Added
Nuveen, LLC469,253$8.12M0.00%−22,985−4.7%Reduced
Hudson Bay Capital Management LP475,000$8.22M0.05%+164,300+52.9%Added
Schroder Investment Management Group485,615$8.41M0.01%+232,506+91.9%Added
Northern Trust Corp525,882$9.10M0.00%+7,188+1.4%Added
Woodline Partners LP530,923$9.19M0.05%+312,073+142.6%Added
Capitolis Liquid Global Markets LLC544,600$9.43M0.07%+544,600New
Ossiam555,953$9.62M0.11%+555,953New
Jump Financial, LLC558,668$9.67M0.12%+293,075+110.3%Added
Jefferies Financial Group Inc.578,205$10.0M0.17%−21,050−3.5%Reduced
Bank of Nova Scotia594,812$10.3M0.02%+594,812New
Ameriprise Financial Inc750,161$13.0M0.00%+283,500+60.8%Added
Royal Bank of Canada797,585$13.8M0.00%+2,650+0.3%Added
Camber Capital Management LP850,000$14.7M2.05%+850,000New
Octagon Capital Advisors LP903,500$15.6M3.43%−1,190,500−56.9%Reduced
Charles Schwab Investment Management Inc989,143$17.1M0.00%+24,644+2.6%Added
Wells Fargo & Company1,043,655$18.1M0.00%+1,039,031+22,470.4%Added
Braidwell LP1,121,034$19.4M0.66%−531,300−32.2%Reduced
BNP Paribas Arbitrage, SA1,298,459$22.5M0.02%+187,750+16.9%Added
Polar Capital Holdings Plc1,352,175$23.4M0.12%−225,000−14.3%Reduced
OrbiMed Advisors LLC1,482,300$25.7M0.65%+50,000+3.5%Added
Deutsche Bank AG1,496,296$25.9M0.01%−280,280−15.8%Reduced
Amundi1,604,105$28.6M0.01%+1,274,523+386.7%Added
Geode Capital Management, LLC1,995,271$34.5M0.00%+45,225+2.3%Added
Norges Bank2,367,224$41.0M0.01%+793,623+50.4%Added
Bank of America Corp2,426,628$42.0M0.00%−704,808−22.5%Reduced
Siren, L.L.C.2,578,396$44.6M2.31%00.0%Unchanged
Jennison Associates LLC2,661,823$46.1M0.03%+184,292+7.4%Added
Marshall Wace, LLP2,704,837$46.8M0.06%+2,681,263+11,373.8%Added
Suvretta Capital Management, LLC2,878,000$49.8M1.88%+1,231,385+74.8%Added
State Street Corp3,562,721$61.7M0.00%−378,684−9.6%Reduced
UBS Group AG4,735,311$82.0M0.02%+1,463,117+44.7%Added
AQR Capital Management LLC5,976,414$103.5M0.09%+1,898,995+46.6%Added
BlackRock, Inc.6,404,999$110.9M0.00%+75,401+1.2%Added
Deep Track Capital, LP7,000,000$121.2M3.90%+2,000,000+40.0%Added
Wellington Management Group LLP8,976,962$155.4M0.03%−3,326,290−27.0%Reduced
Morgan Stanley9,752,201$168.8M0.01%+126,078+1.3%Added
Vanguard Group Inc10,154,751$175.8M0.00%+24,395+0.2%Added
EcoR1 Capital, LLC11,895,808$205.9M12.22%00.0%Unchanged
Avoro Capital Advisors LLC12,222,222$211.6M3.71%00.0%Unchanged
Man Group plc0$00.00%−1,027,792−100.0%Sold out
National Bank of Canada0$00.00%−782,701−100.0%Sold out
Boxer Capital Management, LLC0$00.00%−713,000−100.0%Sold out
Balyasny Asset Management LLC0$00.00%−324,487−100.0%Sold out
ExodusPoint Capital Management, LP0$00.00%−250,414−100.0%Sold out
Macquarie Group Ltd0$00.00%−204,803−100.0%Sold out
Granahan Investment Management Inc0$00.00%−175,696−100.0%Sold out
Candriam Luxembourg S.C.A.0$00.00%−159,054−100.0%Sold out
Alyeska Investment Group, L.P.0$00.00%−150,000−100.0%Sold out
Old West Investment Management, LLC0$00.00%−128,192−100.0%Sold out
Assenagon Asset Management S.A.0$00.00%−74,325−100.0%Sold out
Baird Financial Group, Inc.0$00.00%−55,529−100.0%Sold out
Tudor Investment Corp Et Al0$00.00%−52,980−100.0%Sold out
Envestnet Asset Management Inc0$00.00%−43,717−100.0%Sold out
Bayesian Capital Management, LP0$00.00%−37,900−100.0%Sold out
Bridgefront Capital, LLC0$00.00%−29,070−100.0%Sold out
Scientech Research LLC0$00.00%−23,395−100.0%Sold out
GWN Securities Inc.0$00.00%−27,190−100.0%Sold out
Teachers Retirement System of the State of Kentucky0$00.00%−18,912−100.0%Sold out
Allianz Asset Management GmbH0$00.00%−18,800−100.0%Sold out
Panagora Asset Management Inc0$00.00%−16,701−100.0%Sold out
Aigen Investment Management, LP0$00.00%−15,621−100.0%Sold out
Diversified Trust Co0$00.00%−12,878−100.0%Sold out
Teza Capital Management LLC0$00.00%−11,855−100.0%Sold out
Jain Global LLC0$00.00%−11,719−100.0%Sold out
Lecap Asset Management Ltd0$00.00%−10,759−100.0%Sold out
Qsemble Capital Management, LP0$00.00%−9,670−100.0%Sold out
Kaufman Rossin Wealth, LLC0$00.00%−9,577−100.0%Sold out
Legacy Capital Group California, Inc.0$00.00%−9,554−100.0%Sold out
Stelac Advisory Services LLC0$00.00%−5,520−100.0%Sold out
Corebridge Financial, Inc.0$00.00%−1,901−100.0%Sold out
Coldstream Capital Management Inc0$00.00%−591−100.0%Sold out
Spire Wealth Management0$00.00%−482−100.0%Sold out
AdvisorNet Financial, Inc0$00.00%−415−100.0%Sold out
Ronald Blue Trust, Inc.0$00.00%−305−100.0%Sold out
Clear Street Markets LLC0$00.00%−278−100.0%Sold out
Principal Securities, Inc.0$00.00%−130−100.0%Sold out
Boston Private Wealth LLC0$00.00%−94−100.0%Sold out
Sherman Asset Management, Inc.0$00.00%−63−100.0%Sold out
Quent Capital, LLC0$00.00%−49−100.0%Sold out
Private Wealth Management Group, LLC0$00.00%−42−100.0%Sold out
Carolinas Wealth Consulting LLC0$00.00%−39−100.0%Sold out
Bell Investment Advisors, Inc0$00.00%−32−100.0%Sold out
CVA Family Office, LLC0$00.00%−20−100.0%Sold out
Bokf, NA0$00.00%−16−100.0%Sold out
CoreCap Advisors, LLC0$00.00%−10−100.0%Sold out
Creative Financial Designs Inc0$00.00%−5−100.0%Sold out
Hantz Financial Services, Inc.0$00.00%−6−100.0%Sold out
Avion Wealth0$00.00%−15−100.0%Sold out
Lindbrook Capital, LLC––––Not filed
Sofos Investments, Inc.––––Not filed