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Apellis Pharmaceuticals, Inc.

APLSDelisted May 14, 2026
Industry
Pharmaceutical Preparations
SEC CIK
0001492422

Apellis Pharmaceuticals, Inc. was delisted on May 14, 2026; its insiders filed their last Form 4 on May 14, 2026; 324 institutions reported holding it in 13F filings for Q1 2026, worth $5.56B in total; Soros Fund Management was the only superinvestor holding it.

13F holders, Q2 2025

Institutional positions in Apellis Pharmaceuticals, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
247
−6 vs. Q1 2025
Shares held
131.5M
+3.54M (+2.8%) vs. Q1 2025
Total value
$2.28B
−$523.6M (−18.7%) vs. Q1 2025
New holders
43
108 more added
Sold out
49
68 more reduced

2 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting APLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 247 institutions
Q1 2021: 175 institutionsQ2 2021: 205 institutionsQ3 2021: 181 institutionsQ4 2021: 187 institutionsQ1 2022: 212 institutionsQ2 2022: 212 institutionsQ3 2022: 250 institutionsQ4 2022: 244 institutionsQ1 2023: 282 institutionsQ2 2023: 317 institutionsQ3 2023: 256 institutionsQ4 2023: 284 institutionsQ1 2024: 302 institutionsQ2 2024: 263 institutionsQ3 2024: 265 institutionsQ4 2024: 260 institutionsQ1 2025: 255 institutionsQ2 2025: 247 institutionsQ3 2025: 273 institutionsQ4 2025: 280 institutionsQ1 2026: 324 institutionsQ2 2026: 1 institution
Value heldQ2 2025: $2.28B
Q1 2021: $2.80BQ2 2021: $4.08BQ3 2021: $2.29BQ4 2021: $3.83BQ1 2022: $4.62BQ2 2022: $4.15BQ3 2022: $6.66BQ4 2022: $5.20BQ1 2023: $7.28BQ2 2023: $9.71BQ3 2023: $4.34BQ4 2023: $6.82BQ1 2024: $6.65BQ2 2024: $4.43BQ3 2024: $3.41BQ4 2024: $4.04BQ1 2025: $2.80BQ2 2025: $2.28BQ3 2025: $2.77BQ4 2025: $3.17BQ1 2026: $5.56BQ2 2026: $10.2K
Institutions holding APLS and their total value by quarter
QuarterHoldersValue
Q2 20261$10.2K
Q1 2026324$5.56B
Q4 2025280$3.17B
Q3 2025273$2.77B
Q2 2025247$2.28B
Q1 2025255$2.80B
Q4 2024260$4.04B
Q3 2024265$3.41B
Q2 2024263$4.43B
Q1 2024302$6.65B
Q4 2023284$6.82B
Q3 2023256$4.34B
Q2 2023317$9.71B
Q1 2023282$7.28B
Q4 2022244$5.20B
Q3 2022250$6.66B
Q2 2022212$4.15B
Q1 2022212$4.62B
Q4 2021187$3.83B
Q3 2021181$2.29B
Q2 2021205$4.08B
Q1 2021175$2.80B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Apellis Pharmaceuticals, Inc.; share changes are against Q1 2025.

Institutions holding APLS in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Virtus Investment Advisers, Inc.23,073$399.4K0.14%+12,106+110.4%Added
Toronto Dominion Bank23,437$405.7K0.00%−138,753−85.5%Reduced
Essential Partners LLC23,902$413.7K0.17%+23,902New
Buckingham Strategic Partners24,350$421.5K0.01%+7,783+47.0%Added
Parallax Volatility Advisers, L.P.24,443$423.1K0.02%−3,907−13.8%Reduced
China Universal Asset Management Co., Ltd.25,243$437.0K0.04%+67+0.3%Added
Universal- Beteiligungs- und Servicegesellschaft mbH25,273$437.5K0.00%+9,114+56.4%Added
First Trust Advisors LP26,538$459.4K0.00%−172,671−86.7%Reduced
Virginia Retirement Systems Et Al27,665$478.9K0.00%+3,000+12.2%Added
Profund Advisors LLC28,676$496.4K0.02%−6,981−19.6%Reduced
Ensign Peak Advisors, Inc29,397$508.9K0.00%00.0%Unchanged
Captrust Financial Advisors29,532$511.2K0.00%+252+0.9%Added
Colony Group, LLC29,676$513.7K0.00%+7,793+35.6%Added
Handelsbanken Fonder AB30,200$523.0K0.00%−400−1.3%Reduced
Prelude Capital Management, LLC31,139$539.0K0.05%+31,139New
Alliancebernstein L.P.31,929$552.7K0.00%−12,983−28.9%Reduced
Public Employees Retirement System of Ohio33,470$579.4K0.00%+495+1.5%Added
Janus Henderson Group PLC34,412$595.3K0.00%00.0%Unchanged
Mariner, LLC36,330$628.9K0.00%+23,326+179.4%Added
Guggenheim Capital LLC38,453$665.6K0.01%+3,105+8.8%Added
Wealthedge Investment Advisors, LLC38,572$667.7K0.28%+38,572New
Police & Firemen's Retirement System of New Jersey40,954$708.9K0.01%+2,385+6.2%Added
Mirae Asset Global ETFs Holdings Ltd.40,984$710.3K0.00%+11,425+38.7%Added
Erste Asset Management GmbH42,000$732.1K0.01%00.0%Unchanged
Graham Capital Management, L.P.43,091$745.9K0.02%+14,955+53.2%Added
Voleon Capital Management LP43,139$746.7K0.04%+12,948+42.9%Added
SG Americas Securities, LLC45,103$781.0K0.00%−321,041−87.7%Reduced
Cinctive Capital Management LP47,700$825.7K0.05%+47,700New
Hennion & Walsh Asset Management, Inc.49,014$848.4K0.03%+4,848+11.0%Added
T. Rowe Price Investment Management, Inc.49,308$854.0K0.00%+1,595+3.3%Added
Treasurer of the State of North Carolina50,358$872.0K0.00%+1,353+2.8%Added
DekaBank Deutsche Girozentrale55,000$921.0K0.00%00.0%Unchanged
Pallas Capital Advisors LLC54,849$949.4K0.04%+12,315+29.0%Added
Simplex Trading, LLC55,934$968.0K0.03%+55,934New
Healthcare of Ontario Pension Plan Trust Fund56,000$969.4K0.00%+56,000New
Bayforest Capital Ltd56,639$980.4K0.43%+4,301+8.2%Added
HSBC Holdings PLC57,898$1.00M0.00%+32,899+131.6%Added
Engineers Gate Manager LP58,718$1.02M0.01%+16,546+39.2%Added
The PNC Financial Services Group, Inc.58,856$1.02M0.00%+465+0.8%Added
New York State Common Retirement Fund58,879$1.02M0.00%+10,042+20.6%Added
Landscape Capital Management, L.L.C.64,521$1.12M0.09%+25,533+65.5%Added
Alps Advisors Inc67,761$1.17M0.01%+67,761New
Phocas Financial Corp.71,599$1.24M0.18%+71,599New
Mackenzie Financial Corp74,165$1.28M0.00%+32,632+78.6%Added
Raymond James Financial Inc74,466$1.29M0.00%+22,488+43.3%Added
Ikarian Capital, LLC75,000$1.30M0.43%00.0%Unchanged
Bleakley Financial Group, LLC77,088$1.33M0.03%+3,951+5.4%Added
Walleye Capital LLC81,270$1.41M0.01%−236,172−74.4%Reduced
Schonfeld Strategic Advisors LLC83,916$1.45M0.01%−97,484−53.7%Reduced
Rock Springs Capital Management LP84,300$1.46M0.09%+4,300+5.4%Added
HighVista Strategies LLC86,663$1.50M0.55%−22,051−20.3%Reduced
California State Teachers Retirement System87,929$1.52M0.00%+28,151+47.1%Added
Natixis90,666$1.57M0.01%−564,361−86.2%Reduced
State Board of Administration of Florida Retirement System91,408$1.58M0.00%−410−0.4%Reduced
Price T Rowe Associates Inc92,151$1.60M0.00%+1,451+1.6%Added
Rhenman & Partners Asset Management AB93,250$1.61M0.20%+65,000+230.1%Added
J. Goldman & Co LP93,574$1.62M0.05%+93,574New
State of Wisconsin Investment Board94,404$1.63M0.00%+9,789+11.6%Added
Verition Fund Management LLC95,605$1.65M0.01%−14,905−13.5%Reduced
Legal & General Group Plc96,050$1.66M0.00%+16,980+21.5%Added
Exome Asset Management LLC98,600$1.71M1.41%+98,600New
Dark Forest Capital Management LP104,725$1.81M0.07%+104,725New
EFG Asset Management (North America) Corp.105,024$1.82M0.26%+65,661+166.8%Added
Wealth Enhancement Advisory Services, LLC100,666$1.84M0.00%+30,507+43.5%Added
HRT Financial LP107,200$1.85M0.01%+107,200New
Sphera Funds Management Ltd.114,346$1.98M0.52%−67,000−36.9%Reduced
Cerity Partners LLC114,745$1.99M0.00%+60,301+110.8%Added
J. Safra Sarasin Holding AG115,684$2.00M0.03%+68,588+145.6%Added
Connor, Clark & Lunn Investment Management Ltd.118,724$2.06M0.01%−13,171−10.0%Reduced
Gotham Asset Management, LLC119,229$2.06M0.01%+84,944+247.8%Added
Rhumbline Advisers122,002$2.11M0.00%−2,452−2.0%Reduced
CWM, LLC127,584$2.21M0.01%+29,326+29.8%Added
California Public Employees Retirement System134,637$2.33M0.00%+7,931+6.3%Added
Citigroup Inc138,451$2.40M0.00%−278,168−66.8%Reduced
Steward Partners Investment Advisory, LLC140,975$2.44M0.02%+18,800+15.4%Added
Swiss National Bank143,800$2.49M0.00%+11,200+8.4%Added
Rafferty Asset Management, LLC143,852$2.49M0.01%−36,282−20.1%Reduced
Voya Investment Management LLC150,593$2.61M0.00%+25,192+20.1%Added
Prudential Financial Inc154,010$2.67M0.00%−63,870−29.3%Reduced
Algert Global LLC154,113$2.67M0.06%−184,500−54.5%Reduced
Bank of Montreal159,613$2.76M0.00%+1,040+0.7%Added
PDT Partners, LLC160,058$2.77M0.16%−35,107−18.0%Reduced
Y-Intercept (Hong Kong) Ltd164,275$2.84M0.07%+134,698+455.4%Added
Invesco Ltd.166,135$2.88M0.00%−475,262−74.1%Reduced
Aquatic Capital Management LLC176,704$3.06M0.06%−39,172−18.1%Reduced
Millennium Management LLC202,452$3.50M0.00%−249,521−55.2%Reduced
Fiduciary Trust Co202,536$3.51M0.04%−800−0.4%Reduced
Goldman Sachs Group Inc215,999$3.74M0.00%−91,710−29.8%Reduced
Edgestream Partners, L.P.218,392$3.78M0.11%−22,895−9.5%Reduced
Caption Management, LLC230,888$4.00M0.37%+218,888+1,824.1%Added
JPMorgan Chase & Co234,801$4.06M0.00%−188,999−44.6%Reduced
Bank of New York Mellon Corp243,327$4.21M0.00%−85,846−26.1%Reduced
Jane Street Group, LLC246,199$4.26M0.01%−9,893−3.9%Reduced
D. E. Shaw & Co., Inc.251,069$4.35M0.00%+251,069New
Two Sigma Advisers, LP256,800$4.45M0.01%+65,000+33.9%Added
Barclays PLC273,912$4.74M0.00%+82,675+43.2%Added
UBS Asset Management Americas Inc301,939$5.23M0.00%+79,305+35.6%Added
ING Groep NV308,300$5.34M0.03%+124,100+67.4%Added
Trexquant Investment LP327,421$5.67M0.06%−57,501−14.9%Reduced
Susquehanna International Group, LLP328,726$5.69M0.01%+299,221+1,014.1%Added