Skip to main content

Apellis Pharmaceuticals, Inc.

APLSDelisted May 14, 2026
Industry
Pharmaceutical Preparations
SEC CIK
0001492422

Apellis Pharmaceuticals, Inc. was delisted on May 14, 2026; its insiders filed their last Form 4 on May 14, 2026; 324 institutions reported holding it in 13F filings for Q1 2026, worth $5.56B in total; Soros Fund Management was the only superinvestor holding it.

13F holders, Q4 2024

Institutional positions in Apellis Pharmaceuticals, Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
260
−2 vs. Q3 2024
Shares held
126.7M
+8.67M (+7.3%) vs. Q3 2024
Total value
$4.04B
+$639.2M (+18.8%) vs. Q3 2024
New holders
61
98 more added
Sold out
63
72 more reduced

3 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting APLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2024: 260 institutions
Q1 2021: 175 institutionsQ2 2021: 205 institutionsQ3 2021: 181 institutionsQ4 2021: 187 institutionsQ1 2022: 212 institutionsQ2 2022: 212 institutionsQ3 2022: 250 institutionsQ4 2022: 244 institutionsQ1 2023: 282 institutionsQ2 2023: 317 institutionsQ3 2023: 256 institutionsQ4 2023: 284 institutionsQ1 2024: 302 institutionsQ2 2024: 263 institutionsQ3 2024: 265 institutionsQ4 2024: 260 institutionsQ1 2025: 255 institutionsQ2 2025: 247 institutionsQ3 2025: 273 institutionsQ4 2025: 280 institutionsQ1 2026: 324 institutionsQ2 2026: 1 institution
Value heldQ4 2024: $4.04B
Q1 2021: $2.80BQ2 2021: $4.08BQ3 2021: $2.29BQ4 2021: $3.83BQ1 2022: $4.62BQ2 2022: $4.15BQ3 2022: $6.66BQ4 2022: $5.20BQ1 2023: $7.28BQ2 2023: $9.71BQ3 2023: $4.34BQ4 2023: $6.82BQ1 2024: $6.65BQ2 2024: $4.43BQ3 2024: $3.41BQ4 2024: $4.04BQ1 2025: $2.80BQ2 2025: $2.28BQ3 2025: $2.77BQ4 2025: $3.17BQ1 2026: $5.56BQ2 2026: $10.2K
Institutions holding APLS and their total value by quarter
QuarterHoldersValue
Q2 20261$10.2K
Q1 2026324$5.56B
Q4 2025280$3.17B
Q3 2025273$2.77B
Q2 2025247$2.28B
Q1 2025255$2.80B
Q4 2024260$4.04B
Q3 2024265$3.41B
Q2 2024263$4.43B
Q1 2024302$6.65B
Q4 2023284$6.82B
Q3 2023256$4.34B
Q2 2023317$9.71B
Q1 2023282$7.28B
Q4 2022244$5.20B
Q3 2022250$6.66B
Q2 2022212$4.15B
Q1 2022212$4.62B
Q4 2021187$3.83B
Q3 2021181$2.29B
Q2 2021205$4.08B
Q1 2021175$2.80B

Institutions, Q4 2024

Shares, value and share of portfolio for each institution holding Apellis Pharmaceuticals, Inc.; share changes are against Q3 2024.

Institutions holding APLS in Q4 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Trexquant Investment LP203,008$6.48M0.08%+203,008New
Sphera Funds Management Ltd.206,251$6.58M1.22%−9,622−4.5%Reduced
UBS Asset Management Americas Inc212,887$6.79M0.00%+21,822+11.4%Added
Schroder Investment Management Group219,383$7.00M0.01%00.0%Unchanged
Fiduciary Trust Co229,801$7.33M0.10%−6,265−2.7%Reduced
Rafferty Asset Management, LLC241,474$7.71M0.03%+37,328+18.3%Added
Goldman Sachs Group Inc242,967$7.75M0.00%+47,901+24.6%Added
Renaissance Technologies LLC271,913$8.68M0.01%−100,418−27.0%Reduced
Algert Global LLC282,285$9.01M0.21%+199,874+242.5%Added
MUFG Securities EMEA plc298,000$9.51M0.18%+298,000New
Bank of New York Mellon Corp334,416$10.7M0.00%−9,323−2.7%Reduced
Amundi329,582$10.9M0.00%+326,604+10,967.2%Added
Jefferies Financial Group Inc.341,361$10.9M0.12%+292,850+603.7%Added
Hudson Bay Capital Management LP345,000$11.0M0.07%+85,000+32.7%Added
Voloridge Investment Management, LLC345,885$11.0M0.04%−468,679−57.5%Reduced
Pictet Asset Management Holding SA347,854$11.1M0.01%+49,901+16.7%Added
Price T Rowe Associates Inc358,578$11.4M0.00%−19,878−5.3%Reduced
683 Capital Management, LLC360,000$11.5M1.13%+125,000+53.2%Added
Walleye Capital LLC394,823$12.6M0.12%+292,743+286.8%Added
JPMorgan Chase & Co411,549$13.1M0.00%−3,473,181−89.4%Reduced
Integral Health Asset Management, LLC420,000$13.4M1.19%+420,000New
Nuveen Asset Management, LLC491,107$15.7M0.00%+150,384+44.1%Added
Logos Global Management LP500,000$16.0M1.87%+500,000New
Candriam Luxembourg S.C.A.539,602$17.2M0.10%−140,456−20.7%Reduced
Northern Trust Corp547,276$17.5M0.00%+94,174+20.8%Added
Victory Capital Management Inc562,269$17.9M0.02%+150,363+36.5%Added
Millennium Management LLC575,490$18.4M0.02%+498,104+643.7%Added
Invesco Ltd.603,656$19.3M0.00%−457−0.1%Reduced
Balyasny Asset Management LLC744,194$23.7M0.06%+744,194New
Suvretta Capital Management, LLC793,187$25.3M0.94%+793,187New
BNP Paribas Arbitrage, SA850,823$27.1M0.02%+691,123+432.8%Added
Natixis870,627$27.8M0.19%+870,627New
Ameriprise Financial Inc882,801$28.2M0.01%+22,507+2.6%Added
Charles Schwab Investment Management Inc996,748$31.8M0.01%+40,386+4.2%Added
Toronto Dominion Bank997,053$31.8M0.06%+971,431+3,791.4%Added
Norges Bank1,086,243$34.7M0.00%+18,573+1.7%Added
Point72 Asset Management, L.P.1,267,958$40.5M0.11%+1,267,958New
CIBC World Markets Corp1,285,300$41.0M0.24%+1,285,300New
National Bank of Canada1,385,600$44.2M0.06%+1,385,080+266,361.5%Added
Boxer Capital Management, LLC1,426,000$45.5M3.87%+1,426,000New
Royal Bank of Canada1,518,827$48.5M0.01%+1,376,832+969.6%Added
Polar Capital Holdings Plc1,577,175$50.3M0.28%+495,175+45.8%Added
Bank of America Corp1,680,213$53.6M0.00%+705,209+72.3%Added
Deutsche Bank AG1,778,377$56.7M0.02%+30,867+1.8%Added
Geode Capital Management, LLC1,838,952$58.7M0.00%+28,426+1.6%Added
AQR Capital Management LLC1,856,442$59.2M0.08%+1,039,182+127.2%Added
Braidwell LP2,098,866$67.0M1.99%−1,026,317−32.8%Reduced
FMR LLC2,127,665$67.9M0.00%−772,589−26.6%Reduced
UBS Group AG2,586,739$82.5M0.02%+2,272,055+722.0%Added
Jennison Associates LLC2,760,404$88.1M0.05%+939,289+51.6%Added
Siren, L.L.C.2,816,258$89.9M3.97%+649,034+29.9%Added
Octagon Capital Advisors LP3,006,980$96.0M16.34%00.0%Unchanged
Deep Track Capital, LP4,274,921$136.4M5.11%−125,733−2.9%Reduced
State Street Corp4,525,155$144.4M0.01%+484,294+12.0%Added
BlackRock, Inc.6,477,989$206.7M0.00%+285,621+4.6%Added
Morgan Stanley9,627,227$307.2M0.02%+6,237,442+184.0%Added
Vanguard Group Inc10,046,025$320.6M0.01%+230,450+2.3%Added
Wellington Management Group LLP11,800,849$376.6M0.07%−3,766,120−24.2%Reduced
EcoR1 Capital, LLC11,890,843$379.4M15.20%00.0%Unchanged
Avoro Capital Advisors LLC12,222,222$390.0M5.52%+1,111,111+10.0%Added
Boxer Capital, LLC0$00.00%−1,726,000−100.0%Sold out
Fiera Capital Corp0$00.00%−1,354,469−100.0%Sold out
OrbiMed Advisors LLC0$00.00%−1,270,400−100.0%Sold out
Twinbeech Capital LP0$00.00%−272,252−100.0%Sold out
Standard Life Aberdeen plc0$00.00%−236,724−100.0%Sold out
Caption Management, LLC0$00.00%−216,006−100.0%Sold out
Franklin Resources Inc0$00.00%−215,289−100.0%Sold out
Peregrine Capital Management LLC0$00.00%−114,533−100.0%Sold out
Simplex Trading, LLC0$00.00%−73,982−100.0%Sold out
Tudor Investment Corp Et Al0$00.00%−73,002−100.0%Sold out
Engineers Gate Manager LP0$00.00%−67,625−100.0%Sold out
Two Sigma Investments, LP0$00.00%−58,783−100.0%Sold out
HRT Financial LP0$00.00%−56,423−100.0%Sold out
CenterBook Partners LP0$00.00%−50,687−100.0%Sold out
State of New Jersey Common Pension Fund D0$00.00%−49,795−100.0%Sold out
AlphaCentric Advisors LLC0$00.00%−47,500−100.0%Sold out
Group One Trading, L.P.0$00.00%−42,153−100.0%Sold out
Brinker Capital Investments, LLC0$00.00%−31,418−100.0%Sold out
Orion Portfolio Solutions, LLC0$00.00%−31,418−100.0%Sold out
Bayesian Capital Management, LP0$00.00%−31,200−100.0%Sold out
SEI Investments Co0$00.00%−30,155−100.0%Sold out
Qube Research & Technologies Ltd0$00.00%−27,948−100.0%Sold out
Stifel Financial Corp0$00.00%−27,641−100.0%Sold out
Mutual of America Capital Management LLC0$00.00%−27,211−100.0%Sold out
Skandinaviska Enskilda Banken AB (publ)0$00.00%−25,581−100.0%Sold out
Schonfeld Strategic Advisors LLC0$00.00%−23,839−100.0%Sold out
Brevan Howard Capital Management LP0$00.00%−19,928−100.0%Sold out
Bellevue Group AG0$00.00%−19,046−100.0%Sold out
Graham Capital Management, L.P.0$00.00%−16,873−100.0%Sold out
FORA Capital, LLC0$00.00%−14,623−100.0%Sold out
MML Investors Services, LLC0$00.00%−13,631−100.0%Sold out
Axq Capital, LP0$00.00%−13,314−100.0%Sold out
Oppenheimer Asset Management Inc.0$00.00%−12,636−100.0%Sold out
Lisanti Capital Growth, LLC0$00.00%−12,505−100.0%Sold out
Snowden Capital Advisors LLC0$00.00%−12,288−100.0%Sold out
FIL Ltd0$00.00%−11,467−100.0%Sold out
GTS Securities LLC0$00.00%−11,362−100.0%Sold out
Mariner, LLC0$00.00%−10,625−100.0%Sold out
Sectoral Asset Management Inc0$00.00%−10,300−100.0%Sold out
Ethic Inc.0$00.00%−4,103−100.0%Sold out