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Apellis Pharmaceuticals, Inc.

APLSDelisted May 14, 2026
Industry
Pharmaceutical Preparations
SEC CIK
0001492422

Apellis Pharmaceuticals, Inc. was delisted on May 14, 2026; its insiders filed their last Form 4 on May 14, 2026; 324 institutions reported holding it in 13F filings for Q1 2026, worth $5.56B in total; Soros Fund Management was the only superinvestor holding it.

13F holders, Q1 2024

Institutional positions in Apellis Pharmaceuticals, Inc. as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
302
+20 vs. Q4 2023
Shares held
113.1M
−619.3K (−0.5%) vs. Q4 2023
Total value
$6.65B
−$166.2M (−2.4%) vs. Q4 2023
New holders
66
105 more added
Sold out
46
91 more reduced

2 institutions that held it in Q4 2023 haven't filed for Q1 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting APLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2024: 302 institutions
Q1 2021: 175 institutionsQ2 2021: 205 institutionsQ3 2021: 181 institutionsQ4 2021: 187 institutionsQ1 2022: 212 institutionsQ2 2022: 212 institutionsQ3 2022: 250 institutionsQ4 2022: 244 institutionsQ1 2023: 282 institutionsQ2 2023: 317 institutionsQ3 2023: 256 institutionsQ4 2023: 284 institutionsQ1 2024: 302 institutionsQ2 2024: 263 institutionsQ3 2024: 265 institutionsQ4 2024: 260 institutionsQ1 2025: 255 institutionsQ2 2025: 247 institutionsQ3 2025: 273 institutionsQ4 2025: 280 institutionsQ1 2026: 324 institutionsQ2 2026: 1 institution
Value heldQ1 2024: $6.65B
Q1 2021: $2.80BQ2 2021: $4.08BQ3 2021: $2.29BQ4 2021: $3.83BQ1 2022: $4.62BQ2 2022: $4.15BQ3 2022: $6.66BQ4 2022: $5.20BQ1 2023: $7.28BQ2 2023: $9.71BQ3 2023: $4.34BQ4 2023: $6.82BQ1 2024: $6.65BQ2 2024: $4.43BQ3 2024: $3.41BQ4 2024: $4.04BQ1 2025: $2.80BQ2 2025: $2.28BQ3 2025: $2.77BQ4 2025: $3.17BQ1 2026: $5.56BQ2 2026: $10.2K
Institutions holding APLS and their total value by quarter
QuarterHoldersValue
Q2 20261$10.2K
Q1 2026324$5.56B
Q4 2025280$3.17B
Q3 2025273$2.77B
Q2 2025247$2.28B
Q1 2025255$2.80B
Q4 2024260$4.04B
Q3 2024265$3.41B
Q2 2024263$4.43B
Q1 2024302$6.65B
Q4 2023284$6.82B
Q3 2023256$4.34B
Q2 2023317$9.71B
Q1 2023282$7.28B
Q4 2022244$5.20B
Q3 2022250$6.66B
Q2 2022212$4.15B
Q1 2022212$4.62B
Q4 2021187$3.83B
Q3 2021181$2.29B
Q2 2021205$4.08B
Q1 2021175$2.80B

Institutions, Q1 2024

Shares, value and share of portfolio for each institution holding Apellis Pharmaceuticals, Inc.; share changes are against Q4 2023.

Institutions holding APLS in Q1 2024
InstitutionSharesValue% of portfolioChange in sharesAction
PDT Partners, LLC56,521$3.32M0.31%+4,570+8.8%Added
The PNC Financial Services Group, Inc.58,610$3.45M0.00%−61,175−51.1%Reduced
Granahan Investment Management Inc66,597$3.91M0.14%+24,356+57.7%Added
Nisa Investment Advisors, LLC67,350$3.96M0.03%00.0%Unchanged
Dimensional Fund Advisors LP68,144$4.01M0.00%+32,577+91.6%Added
HRT Financial LP68,575$4.03M0.02%−7,337−9.7%Reduced
Saturn V Capital Management LLC71,463$4.20M1.68%−71,464−50.0%Reduced
California State Teachers Retirement System74,370$4.37M0.01%−15,821−17.5%Reduced
Frontier Capital Management Co LLC78,048$4.59M0.04%+78,048New
Simplicity Wealth,LLC78,247$4.60M0.11%+78,247New
Bleakley Financial Group, LLC78,253$4.60M0.13%+70.0%Added
Credit Suisse AG80,642$4.74M0.00%−4,929−5.8%Reduced
PFM Health Sciences, LP82,952$4.88M0.24%+82,952New
Principal Financial Group Inc84,604$4.97M0.00%+60,741+254.5%Added
Legal & General Group Plc85,844$5.05M0.00%+2,373+2.8%Added
Lisanti Capital Growth, LLC89,210$5.24M1.28%+42,905+92.7%Added
Peregrine Capital Management LLC92,660$5.45M0.16%+92,660New
Envestnet Asset Management Inc94,605$5.56M0.00%+8,177+9.5%Added
HSBC Holdings PLC98,550$5.79M0.00%+98,550New
Royal Bank of Canada101,334$5.96M0.00%−16,276−13.8%Reduced
Walleye Capital LLC110,799$6.51M0.07%−36,875−25.0%Reduced
UBS Group AG111,292$6.54M0.00%+16,258+17.1%Added
Allspring Global Investments Holdings, LLC115,453$6.79M0.01%+56,178+94.8%Added
Rhumbline Advisers120,921$7.11M0.01%−12,665−9.5%Reduced
Manufacturers Life Insurance Company, The123,330$7.25M0.01%+17,328+16.3%Added
Jane Street Group, LLC129,009$7.58M0.01%−305,692−70.3%Reduced
Ghost Tree Capital, LLC130,000$7.64M2.46%+130,000New
Bank of Montreal132,937$7.83M0.00%−336,947−71.7%Reduced
UBS Asset Management Americas Inc139,325$8.19M0.00%−2,443−1.7%Reduced
Senator Investment Group LP140,000$8.23M0.37%+140,000New
Swiss National Bank140,300$8.25M0.01%−22,100−13.6%Reduced
Wells Fargo & Company145,035$8.53M0.00%+12,468+9.4%Added
California Public Employees Retirement System145,833$8.57M0.01%00.0%Unchanged
Rafferty Asset Management, LLC148,801$8.75M0.03%+5,683+4.0%Added
Integral Health Asset Management, LLC150,000$8.82M0.87%+150,000New
Redmile Group, LLC155,000$9.11M0.33%+155,000New
Affinity Asset Advisors, LLC165,000$9.70M1.58%+90,000+120.0%Added
Marshall Wace, LLP171,873$10.1M0.02%−59,003−25.6%Reduced
Rhenman & Partners Asset Management AB178,395$10.5M0.99%+77,995+77.7%Added
Woodline Partners LP186,998$11.0M0.10%+774+0.4%Added
Standard Life Aberdeen plc189,813$11.2M0.02%+20,762+12.3%Added
Amundi248,483$11.8M0.01%+7,112+2.9%Added
Eventide Asset Management, LLC209,794$12.3M0.19%00.0%Unchanged
683 Capital Management, LLC215,000$12.6M1.29%+85,000+65.4%Added
Macquarie Group Ltd221,654$13.0M0.01%−361,775−62.0%Reduced
Vestal Point Capital, LP225,000$13.2M1.09%+225,000New
Franklin Resources Inc226,649$13.3M0.00%−3,141−1.4%Reduced
Balyasny Asset Management LLC232,243$13.7M0.04%+232,243New
Fiduciary Trust Co240,986$14.2M0.22%−1,621−0.7%Reduced
Susquehanna International Group, LLP244,261$14.4M0.02%−138,571−36.2%Reduced
Prudential Financial Inc245,560$14.4M0.02%−81,000−24.8%Reduced
Ensign Peak Advisors, Inc260,274$15.3M0.03%+14,708+6.0%Added
Citigroup Inc261,708$15.4M0.02%+175,167+202.4%Added
Point72 Asset Management, L.P.267,823$15.7M0.05%+267,823New
Nuveen Asset Management, LLC270,576$15.9M0.00%+560.0%Added
Altitude Crest Partners Inc.287,277$16.9M7.23%+135,077+88.7%Added
Goldman Sachs Group Inc319,476$18.8M0.00%+8,893+2.9%Added
Bank of New York Mellon Corp322,922$19.0M0.00%−49,333−13.3%Reduced
New York State Common Retirement Fund325,926$19.2M0.03%−14,581−4.3%Reduced
Cormorant Asset Management, LP400,000$23.5M1.04%−225,000−36.0%Reduced
First Trust Advisors LP406,483$23.9M0.02%+312,515+332.6%Added
Northern Trust Corp440,456$25.9M0.00%−8,270−1.8%Reduced
TD Asset Management Inc459,402$27.0M0.03%−23,920−4.9%Reduced
Bellevue Group AG473,915$27.9M0.42%−347,885−42.3%Reduced
Victory Capital Management Inc491,897$28.9M0.03%−124,375−20.2%Reduced
Voya Investment Management LLC494,692$29.1M0.03%+238,159+92.8%Added
Driehaus Capital Management LLC503,039$29.6M0.29%+21,538+4.5%Added
Ameriprise Financial Inc531,362$31.2M0.01%−34,218−6.1%Reduced
Iron Triangle Partners LP550,000$32.3M3.35%+550,000New
Candriam Luxembourg S.C.A.584,925$34.4M0.22%+247,418+73.3%Added
Bank of America Corp723,444$42.5M0.00%+289,107+66.6%Added
Invesco Ltd.762,115$44.8M0.01%+243,278+46.9%Added
Millennium Management LLC785,396$46.2M0.04%+772,869+6,169.6%Added
Logos Global Management LP800,000$47.0M4.95%−150,000−15.8%Reduced
Eagle Asset Management Inc845,533$50.5M0.26%+399,533+89.6%Added
Frazier Life Sciences Management, L.P.885,165$52.0M2.20%00.0%Unchanged
Charles Schwab Investment Management Inc924,562$54.3M0.01%+20,153+2.2%Added
Fiera Capital Corp948,437$55.7M0.16%+29,347+3.2%Added
Deep Track Capital, LP1,000,000$58.8M1.69%+1,000,000New
Norges Bank1,007,920$59.2M0.01%+61,707+6.5%Added
Polar Capital Holdings Plc1,054,440$62.0M0.37%+1,000+0.1%Added
Pictet Asset Management Holding SA1,073,234$63.0M0.07%−271,329−20.2%Reduced
Citadel Advisors LLC1,186,082$69.7M0.07%+900,965+316.0%Added
OrbiMed Advisors LLC1,297,800$76.3M1.49%+375,600+40.7%Added
Artal Group S.A.1,315,282$77.3M1.99%−106,064−7.5%Reduced
Deutsche Bank AG1,611,773$94.7M0.04%+754,774+88.1%Added
Morgan Stanley1,637,618$96.3M0.01%−1,459,523−47.1%Reduced
Geode Capital Management, LLC1,689,890$99.4M0.01%+59,248+3.6%Added
Boxer Capital, LLC1,726,000$101.5M5.01%00.0%Unchanged
Assenagon Asset Management S.A.2,023,614$118.9M0.32%−121,390−5.7%Reduced
FMR LLC2,178,742$128.1M0.01%+86,278+4.1%Added
JPMorgan Chase & Co2,214,309$130.2M0.01%−359,824−14.0%Reduced
Price T Rowe Associates Inc2,459,246$144.6M0.02%−1,0930.0%Reduced
Octagon Capital Advisors LP2,806,980$165.0M20.06%00.0%Unchanged
State Street Corp2,909,528$171.0M0.01%−5,894−0.2%Reduced
Jennison Associates LLC3,240,513$190.5M0.13%−35,409−1.1%Reduced
T. Rowe Price Investment Management, Inc.4,605,721$270.7M0.17%−1,697,863−26.9%Reduced
BlackRock Inc.5,494,591$323.0M0.01%+113,338+2.1%Added
Vanguard Group Inc9,505,866$558.8M0.01%−49,812−0.5%Reduced
Avoro Capital Advisors LLC11,111,111$653.1M7.62%00.0%Unchanged