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Apellis Pharmaceuticals, Inc.

APLSDelisted May 14, 2026
Industry
Pharmaceutical Preparations
SEC CIK
0001492422

Apellis Pharmaceuticals, Inc. was delisted on May 14, 2026; its insiders filed their last Form 4 on May 14, 2026; 324 institutions reported holding it in 13F filings for Q1 2026, worth $5.56B in total; Soros Fund Management was the only superinvestor holding it.

13F holders, Q4 2023

Institutional positions in Apellis Pharmaceuticals, Inc. as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
284
+32 vs. Q3 2023
Shares held
113.8M
−76.3K (−0.1%) vs. Q3 2023
Total value
$6.82B
+$2.48B (+57.1%) vs. Q3 2023
New holders
65
79 more added
Sold out
33
110 more reduced

4 institutions that held it in Q3 2023 haven't filed for Q4 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting APLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2023: 284 institutions
Q1 2021: 175 institutionsQ2 2021: 205 institutionsQ3 2021: 181 institutionsQ4 2021: 187 institutionsQ1 2022: 212 institutionsQ2 2022: 212 institutionsQ3 2022: 250 institutionsQ4 2022: 244 institutionsQ1 2023: 282 institutionsQ2 2023: 317 institutionsQ3 2023: 256 institutionsQ4 2023: 284 institutionsQ1 2024: 302 institutionsQ2 2024: 263 institutionsQ3 2024: 265 institutionsQ4 2024: 260 institutionsQ1 2025: 255 institutionsQ2 2025: 247 institutionsQ3 2025: 273 institutionsQ4 2025: 280 institutionsQ1 2026: 324 institutionsQ2 2026: 1 institution
Value heldQ4 2023: $6.82B
Q1 2021: $2.80BQ2 2021: $4.08BQ3 2021: $2.29BQ4 2021: $3.83BQ1 2022: $4.62BQ2 2022: $4.15BQ3 2022: $6.66BQ4 2022: $5.20BQ1 2023: $7.28BQ2 2023: $9.71BQ3 2023: $4.34BQ4 2023: $6.82BQ1 2024: $6.65BQ2 2024: $4.43BQ3 2024: $3.41BQ4 2024: $4.04BQ1 2025: $2.80BQ2 2025: $2.28BQ3 2025: $2.77BQ4 2025: $3.17BQ1 2026: $5.56BQ2 2026: $10.2K
Institutions holding APLS and their total value by quarter
QuarterHoldersValue
Q2 20261$10.2K
Q1 2026324$5.56B
Q4 2025280$3.17B
Q3 2025273$2.77B
Q2 2025247$2.28B
Q1 2025255$2.80B
Q4 2024260$4.04B
Q3 2024265$3.41B
Q2 2024263$4.43B
Q1 2024302$6.65B
Q4 2023284$6.82B
Q3 2023256$4.34B
Q2 2023317$9.71B
Q1 2023282$7.28B
Q4 2022244$5.20B
Q3 2022250$6.66B
Q2 2022212$4.15B
Q1 2022212$4.62B
Q4 2021187$3.83B
Q3 2021181$2.29B
Q2 2021205$4.08B
Q1 2021175$2.80B

Institutions, Q4 2023

Shares, value and share of portfolio for each institution holding Apellis Pharmaceuticals, Inc.; share changes are against Q3 2023.

Institutions holding APLS in Q4 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Citigroup Inc86,541$5.18M0.01%−30,355−26.0%Reduced
California State Teachers Retirement System90,191$5.40M0.01%−4,078−4.3%Reduced
Natixis92,058$5.51M0.04%+83,558+983.0%Added
First Trust Advisors LP93,968$5.62M0.01%−304,170−76.4%Reduced
UBS Group AG95,034$5.69M0.00%+91,168+2,358.2%Added
Thrivent Financial for Lutherans97,716$5.85M0.01%+18,255+23.0%Added
Rhenman & Partners Asset Management AB100,400$6.01M0.60%−114,600−53.3%Reduced
Manufacturers Life Insurance Company, The106,002$6.35M0.00%+51,737+95.3%Added
Cutter Capital Management, LP108,000$6.46M3.09%+108,000New
LMR Partners LLP114,069$6.83M0.17%+56,940+99.7%Added
Royal Bank of Canada117,610$7.04M0.00%−1,054−0.9%Reduced
The PNC Financial Services Group, Inc.119,785$7.17M0.01%+450.0%Added
683 Capital Management, LLC130,000$7.78M0.78%−110,000−45.8%Reduced
Wells Fargo & Company132,567$7.94M0.00%−23,140−14.9%Reduced
Rhumbline Advisers133,586$8.00M0.01%+1,292+1.0%Added
UBS Asset Management Americas Inc141,768$8.49M0.00%−4,178−2.9%Reduced
Saturn V Capital Management LLC142,927$8.56M3.27%+142,927New
Rafferty Asset Management, LLC143,118$8.57M0.04%−71,043−33.2%Reduced
California Public Employees Retirement System145,833$8.73M0.01%−38,011−20.7%Reduced
Walleye Capital LLC147,674$8.84M0.12%+13,691+10.2%Added
Ally Bridge Group (NY) LLC150,000$8.98M6.46%−31,805−17.5%Reduced
Altitude Crest Partners Inc.152,200$9.11M6.10%+152,200New
Swiss National Bank162,400$9.72M0.01%−16,800−9.4%Reduced
BNP Paribas Arbitrage, SA167,488$10.0M0.02%−68,867−29.1%Reduced
Standard Life Aberdeen plc169,051$10.1M0.02%+169,051New
Woodline Partners LP186,224$11.1M0.12%+186,224New
Barclays PLC196,391$11.8M0.01%−146,498−42.7%Reduced
Great Lakes Advisors, LLC208,163$12.5M0.12%+208,163New
Eventide Asset Management, LLC209,794$12.6M0.20%+209,794New
Franklin Resources Inc229,790$13.8M0.01%+229,790New
Marshall Wace, LLP230,876$13.8M0.03%+61,582+36.4%Added
Fiduciary Trust Co242,607$14.5M0.24%−22,600−8.5%Reduced
Ensign Peak Advisors, Inc245,566$14.7M0.03%+60,000+32.3%Added
Group One Trading, L.P.253,905$15.2M0.48%+27,221+12.0%Added
Voya Investment Management LLC256,533$15.4M0.02%+174,366+212.2%Added
Nuveen Asset Management, LLC270,520$16.2M0.01%−2,993−1.1%Reduced
Citadel Advisors LLC285,117$17.1M0.02%+270,370+1,833.4%Added
Amundi241,371$17.5M0.01%−37,593−13.5%Reduced
Goldman Sachs Group Inc310,583$18.6M0.00%−21,210−6.4%Reduced
Prudential Financial Inc326,560$19.5M0.03%+23,000+7.6%Added
Candriam Luxembourg S.C.A.337,507$20.2M0.14%+11,000+3.4%Added
New York State Common Retirement Fund340,507$20.4M0.03%−62,437−15.5%Reduced
Bank of New York Mellon Corp372,255$22.3M0.00%+11,968+3.3%Added
Susquehanna International Group, LLP382,832$22.9M0.04%+10,047+2.7%Added
Caption Management, LLC393,031$23.5M2.56%+119,781+43.8%Added
Bank of America Corp434,337$26.0M0.00%−270,618−38.4%Reduced
Jane Street Group, LLC434,701$26.0M0.03%+161,475+59.1%Added
Eagle Asset Management Inc446,000$26.7M0.14%−3,970−0.9%Reduced
Northern Trust Corp448,726$26.9M0.00%−1,704−0.4%Reduced
Driehaus Capital Management LLC481,501$28.8M0.35%+300,177+165.5%Added
TD Asset Management Inc483,322$28.9M0.03%+112,465+30.3%Added
Bank of Montreal469,884$29.6M0.02%+37,911+8.8%Added
Invesco Ltd.518,837$31.1M0.01%−21,839−4.0%Reduced
Ameriprise Financial Inc565,580$33.9M0.01%+213,188+60.5%Added
Macquarie Group Ltd583,429$34.9M0.04%−493,119−45.8%Reduced
Victory Capital Management Inc616,272$36.9M0.04%−122,239−16.6%Reduced
Cormorant Asset Management, LP625,000$37.4M1.79%−1,375,000−68.8%Reduced
Bellevue Group AG821,800$49.2M0.75%+27,959+3.5%Added
Deutsche Bank AG856,999$51.3M0.03%+532,705+164.3%Added
Frazier Life Sciences Management, L.P.885,165$53.0M2.83%+271,122+44.2%Added
Charles Schwab Investment Management Inc904,409$54.1M0.01%+25,052+2.8%Added
Fiera Capital Corp919,090$55.0M0.17%−600−0.1%Reduced
OrbiMed Advisors LLC922,200$55.2M1.11%−338,300−26.8%Reduced
Norges Bank946,213$56.6M0.01%−105,980−10.1%Reduced
Logos Global Management LP950,000$56.9M6.32%+200,000+26.7%Added
Polar Capital Holdings Plc1,053,440$63.1M0.44%−4350.0%Reduced
Pictet Asset Management Holding SA1,344,563$80.5M0.09%+610,413+83.1%Added
Artal Group S.A.1,421,346$85.1M2.90%−243,226−14.6%Reduced
Geode Capital Management, LLC1,630,642$97.6M0.01%+75,816+4.9%Added
Boxer Capital, LLC1,726,000$103.3M5.15%00.0%Unchanged
FMR LLC2,092,464$125.3M0.01%−167,302−7.4%Reduced
Assenagon Asset Management S.A.2,145,004$128.4M0.39%+1,121,497+109.6%Added
Price T Rowe Associates Inc2,460,339$147.3M0.02%+677,098+38.0%Added
JPMorgan Chase & Co2,574,133$154.1M0.02%+356,386+16.1%Added
Octagon Capital Advisors LP2,806,980$168.0M26.88%−323,020−10.3%Reduced
State Street Corp2,915,422$174.5M0.01%−322,692−10.0%Reduced
Morgan Stanley3,097,141$185.4M0.02%+1,488,145+92.5%Added
Jennison Associates LLC3,275,922$196.1M0.15%−266,287−7.5%Reduced
BlackRock Inc.5,381,253$322.1M0.01%+108,507+2.1%Added
T. Rowe Price Investment Management, Inc.6,303,584$377.3M0.25%−215,887−3.3%Reduced
Vanguard Group Inc9,555,678$572.0M0.01%+85,701+0.9%Added
Avoro Capital Advisors LLC11,111,111$665.1M9.19%00.0%Unchanged
EcoR1 Capital, LLC11,173,068$668.8M17.38%+273,209+2.5%Added
Wellington Management Group LLP16,445,290$984.4M0.18%+1,278,246+8.4%Added
Slate Path Capital LP0$00.00%−2,068,000−100.0%Sold out
Iron Triangle Partners LP0$00.00%−880,000−100.0%Sold out
Westfield Capital Management Co LP0$00.00%−548,870−100.0%Sold out
Eversept Partners, LP0$00.00%−122,643−100.0%Sold out
Banque Pictet & Cie SA0$00.00%−102,242−100.0%Sold out
Voloridge Investment Management, LLC0$00.00%−54,263−100.0%Sold out
HSBC Holdings PLC0$00.00%−50,544−100.0%Sold out
General American Investors Co Inc0$00.00%−45,000−100.0%Sold out
Frontier Capital Management Co LLC0$00.00%−34,600−100.0%Sold out
Aquatic Capital Management LLC0$00.00%−29,800−100.0%Sold out
Virtu Financial LLC0$00.00%−23,235−100.0%Sold out
Seven Eight Capital, LP0$00.00%−22,188−100.0%Sold out
XTX Topco Ltd0$00.00%−12,796−100.0%Sold out
Hudson Bay Capital Management LP0$00.00%−12,500−100.0%Sold out
Van Eck Associates Corp0$00.00%−10,601−100.0%Sold out
Sherbrooke Park Advisers LLC0$00.00%−9,371−100.0%Sold out