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Apellis Pharmaceuticals, Inc.

APLSDelisted May 14, 2026
Industry
Pharmaceutical Preparations
SEC CIK
0001492422

Apellis Pharmaceuticals, Inc. was delisted on May 14, 2026; its insiders filed their last Form 4 on May 14, 2026; 324 institutions reported holding it in 13F filings for Q1 2026, worth $5.56B in total; Soros Fund Management was the only superinvestor holding it.

13F holders, Q2 2023

Institutional positions in Apellis Pharmaceuticals, Inc. as of Jun 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
317
+37 vs. Q1 2023
Shares held
106.6M
−3.79M (−3.4%) vs. Q1 2023
Total value
$9.71B
+$2.43B (+33.4%) vs. Q1 2023
New holders
69
100 more added
Sold out
32
120 more reduced

2 institutions that held it in Q1 2023 haven't filed for Q2 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting APLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2023: 317 institutions
Q1 2021: 175 institutionsQ2 2021: 205 institutionsQ3 2021: 181 institutionsQ4 2021: 187 institutionsQ1 2022: 212 institutionsQ2 2022: 212 institutionsQ3 2022: 250 institutionsQ4 2022: 244 institutionsQ1 2023: 282 institutionsQ2 2023: 317 institutionsQ3 2023: 256 institutionsQ4 2023: 284 institutionsQ1 2024: 302 institutionsQ2 2024: 263 institutionsQ3 2024: 265 institutionsQ4 2024: 260 institutionsQ1 2025: 255 institutionsQ2 2025: 247 institutionsQ3 2025: 273 institutionsQ4 2025: 280 institutionsQ1 2026: 324 institutionsQ2 2026: 1 institution
Value heldQ2 2023: $9.71B
Q1 2021: $2.80BQ2 2021: $4.08BQ3 2021: $2.29BQ4 2021: $3.83BQ1 2022: $4.62BQ2 2022: $4.15BQ3 2022: $6.66BQ4 2022: $5.20BQ1 2023: $7.28BQ2 2023: $9.71BQ3 2023: $4.34BQ4 2023: $6.82BQ1 2024: $6.65BQ2 2024: $4.43BQ3 2024: $3.41BQ4 2024: $4.04BQ1 2025: $2.80BQ2 2025: $2.28BQ3 2025: $2.77BQ4 2025: $3.17BQ1 2026: $5.56BQ2 2026: $10.2K
Institutions holding APLS and their total value by quarter
QuarterHoldersValue
Q2 20261$10.2K
Q1 2026324$5.56B
Q4 2025280$3.17B
Q3 2025273$2.77B
Q2 2025247$2.28B
Q1 2025255$2.80B
Q4 2024260$4.04B
Q3 2024265$3.41B
Q2 2024263$4.43B
Q1 2024302$6.65B
Q4 2023284$6.82B
Q3 2023256$4.34B
Q2 2023317$9.71B
Q1 2023282$7.28B
Q4 2022244$5.20B
Q3 2022250$6.66B
Q2 2022212$4.15B
Q1 2022212$4.62B
Q4 2021187$3.83B
Q3 2021181$2.29B
Q2 2021205$4.08B
Q1 2021175$2.80B

Institutions, Q2 2023

Shares, value and share of portfolio for each institution holding Apellis Pharmaceuticals, Inc.; share changes are against Q1 2023.

Institutions holding APLS in Q2 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Integral Health Asset Management, LLC72,000$6.56M0.86%+72,000New
UBS Asset Management Americas Inc99,804$6.58M0.00%00.0%Unchanged
Simplex Trading, LLC76,011$6.92M0.29%+72,588+2,120.6%Added
State of Wisconsin Investment Board76,820$7.00M0.02%−4,764−5.8%Reduced
First Trust Advisors LP77,291$7.04M0.01%+28,969+59.9%Added
Bank of Montreal77,926$7.11M0.00%−128,622−62.3%Reduced
Sawtooth Solutions, LLC78,687$7.17M0.20%−103,190−56.7%Reduced
Bleakley Financial Group, LLC78,687$7.17M0.22%−103,190−56.7%Reduced
Citigroup Inc79,985$7.29M0.01%−43,422−35.2%Reduced
Canada Pension Plan Investment Board82,300$7.50M0.01%00.0%Unchanged
Clough Capital Partners L P83,679$7.62M0.77%+55,800+200.2%Added
Legal & General Group Plc84,151$7.67M0.00%−2,517−2.9%Reduced
Wells Fargo & Company92,195$8.40M0.00%−13,423−12.7%Reduced
Rafferty Asset Management, LLC92,268$8.41M0.05%−17,130−15.7%Reduced
Credit Suisse AG93,883$8.55M0.01%+9,935+11.8%Added
Qube Research & Technologies Ltd94,783$8.63M0.03%+94,783New
UBS Group AG96,455$8.79M0.00%−7,909−7.6%Reduced
Kornitzer Capital Management Inc100,545$9.16M0.18%+100,545New
SG Americas Securities, LLC101,111$9.21M0.08%+90,048+814.0%Added
Artia Global Partners LP102,940$9.38M3.23%+102,940New
California State Teachers Retirement System104,487$9.52M0.01%−8,116−7.2%Reduced
Polar Asset Management Partners Inc.105,810$9.64M0.19%+6,600+6.7%Added
Banque Pictet & Cie SA107,135$9.76M0.09%−31,467−22.7%Reduced
Saturn V Capital Management LLC107,406$9.78M5.43%−15,759−12.8%Reduced
Granahan Investment Management Inc113,775$10.4M0.32%−49,676−30.4%Reduced
Ergoteles LLC114,713$10.5M0.50%+114,713New
The PNC Financial Services Group, Inc.122,351$11.1M0.01%+60,886+99.1%Added
Allspring Global Investments Holdings, LLC128,655$11.7M0.02%−2,256−1.7%Reduced
International Biotechnology Trust PLC129,700$11.8M3.60%+98,000+309.1%Added
Senator Investment Group LP130,000$11.8M0.54%+130,000New
Dimensional Fund Advisors LP131,787$12.0M0.00%+37,801+40.2%Added
Rhumbline Advisers132,873$12.1M0.01%+1,912+1.5%Added
Ikarian Capital, LLC133,800$12.2M4.30%+33,800+33.8%Added
Russell Investments Group, Ltd.137,527$12.5M0.02%−673−0.5%Reduced
Renaissance Technologies LLC138,513$12.6M0.02%+138,513New
Royal Bank of Canada140,485$12.8M0.00%+3,242+2.4%Added
Ameriprise Financial Inc141,078$12.9M0.00%+61,405+77.1%Added
Voloridge Investment Management, LLC143,402$13.1M0.06%+77,167+116.5%Added
Sectoral Asset Management Inc143,859$13.1M2.19%−28,631−16.6%Reduced
Federated Hermes, Inc.147,465$13.4M0.03%−363,837−71.2%Reduced
Connor, Clark & Lunn Investment Management Ltd.149,976$13.7M0.07%−2,019−1.3%Reduced
Schonfeld Strategic Advisors LLC164,203$15.0M0.13%+88,176+116.0%Added
Franklin Resources Inc165,710$15.1M0.01%+65,449+65.3%Added
Manufacturers Life Insurance Company, The169,673$15.5M0.01%+33,077+24.2%Added
Tekla Capital Management LLC173,248$15.8M0.62%+38,124+28.2%Added
AXA S.A.173,495$15.8M0.05%+2,386+1.4%Added
Swiss National Bank175,700$16.0M0.01%−15,300−8.0%Reduced
Prudential Financial Inc177,080$16.1M0.02%−259−0.1%Reduced
Ghost Tree Capital, LLC180,000$16.4M5.92%+15,380+9.3%Added
Fred Alger Management, LLC181,995$16.6M0.08%−249−0.1%Reduced
California Public Employees Retirement System182,188$16.6M0.01%+40,182+28.3%Added
Rhenman & Partners Asset Management AB190,000$17.3M1.82%+5,000+2.7%Added
Voya Investment Management LLC221,414$20.2M0.02%−57,772−20.7%Reduced
Finepoint Capital LP241,690$22.0M7.62%−42,000−14.8%Reduced
Nuveen Asset Management, LLC262,398$23.9M0.01%−87,156−24.9%Reduced
Fiduciary Trust Co273,916$25.0M0.44%−268,375−49.5%Reduced
PFM Health Sciences, LP274,498$25.0M1.01%−9,771−3.4%Reduced
Acuta Capital Partners, LLC297,596$27.1M18.37%+7,096+2.4%Added
New York State Common Retirement Fund300,995$27.4M0.04%+57,875+23.8%Added
Balyasny Asset Management LLC304,169$27.7M0.08%−313,728−50.8%Reduced
HRT Financial LP309,024$28.2M0.26%+309,024New
Barclays PLC312,230$28.4M0.02%+70,049+28.9%Added
Deerfield Management Company, L.P. (Series C)313,289$28.5M0.61%+313,289New
Susquehanna International Group, LLP315,910$28.8M0.05%+234,114+286.2%Added
Candriam Luxembourg S.C.A.326,507$29.7M0.21%−117,000−26.4%Reduced
Marshall Wace, LLP342,352$31.2M0.07%+249,906+270.3%Added
Driehaus Capital Management LLC347,376$31.6M0.40%+76,683+28.3%Added
Bank of New York Mellon Corp357,289$32.5M0.01%−35,107−8.9%Reduced
Eventide Asset Management, LLC397,141$36.2M0.61%−97,859−19.8%Reduced
Victory Capital Management Inc400,957$36.5M0.04%−161,212−28.7%Reduced
Bank of America Corp409,842$37.3M0.00%−197,893−32.6%Reduced
Nicholas Investment Partners, LP414,419$37.8M2.58%+77,468+23.0%Added
Eagle Asset Management Inc450,932$41.1M0.23%+221,550+96.6%Added
Polar Capital Holdings Plc465,000$42.4M0.29%00.0%Unchanged
Avidity Partners Management LP468,700$42.7M1.49%+468,700New
Deutsche Bank AG478,366$43.6M0.02%−121,062−20.2%Reduced
TD Asset Management Inc478,726$43.6M0.05%+100,758+26.7%Added
Jane Street Group, LLC481,082$43.8M0.06%+417,698+659.0%Added
Assenagon Asset Management S.A.498,710$45.4M0.18%−244,536−32.9%Reduced
Bellevue Group AG518,495$47.2M0.67%−590,887−53.3%Reduced
Laurion Capital Management LP522,929$47.6M2.04%+148,590+39.7%Added
D. E. Shaw & Co., Inc.527,811$48.1M0.07%+114,958+27.8%Added
Fiera Capital Corp527,920$48.1M0.14%−12,462−2.3%Reduced
Citadel Advisors LLC528,572$48.2M0.05%+354,512+203.7%Added
Westfield Capital Management Co LP596,232$54.3M0.35%−196,014−24.7%Reduced
Logos Global Management LP625,000$56.9M7.86%−175,000−21.9%Reduced
Goldman Sachs Group Inc634,897$57.8M0.01%−28,298−4.3%Reduced
1832 Asset Management L.P.661,700$60.3M0.12%+530,800+405.5%Added
Morgan Stanley756,665$68.9M0.01%+3,803+0.5%Added
Macquarie Group Ltd775,480$70.6M0.08%−635,999−45.1%Reduced
Perceptive Advisors LLC812,037$74.0M2.15%+256,693+46.2%Added
Charles Schwab Investment Management Inc828,522$75.5M0.02%−154,987−15.8%Reduced
Northern Trust Corp852,272$77.6M0.01%−16,916−1.9%Reduced
OrbiMed Advisors LLC910,200$82.9M1.61%00.0%Unchanged
Millennium Management LLC918,811$83.7M0.09%+370,610+67.6%Added
Pictet Asset Management SA928,624$84.6M0.10%+478,585+106.3%Added
Norges Bank1,023,026$93.2M0.02%+91,516+9.8%Added
Artal Group S.A.1,050,067$95.7M3.06%−166,245−13.7%Reduced
Lord, Abbett & Co. LLC1,068,143$97.3M0.33%+163,915+18.1%Added
Invesco Ltd.1,152,396$105.0M0.03%+111,415+10.7%Added