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Apellis Pharmaceuticals, Inc.

APLSDelisted May 14, 2026
Industry
Pharmaceutical Preparations
SEC CIK
0001492422

Apellis Pharmaceuticals, Inc. was delisted on May 14, 2026; its insiders filed their last Form 4 on May 14, 2026; 324 institutions reported holding it in 13F filings for Q1 2026, worth $5.56B in total; Soros Fund Management was the only superinvestor holding it.

13F holders, Q1 2023

Institutional positions in Apellis Pharmaceuticals, Inc. as of Mar 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
282
+41 vs. Q4 2022
Shares held
110.4M
+9.95M (+9.9%) vs. Q4 2022
Total value
$7.28B
+$2.09B (+40.2%) vs. Q4 2022
New holders
68
106 more added
Sold out
27
78 more reduced

3 institutions that held it in Q4 2022 haven't filed for Q1 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting APLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2023: 282 institutions
Q1 2021: 175 institutionsQ2 2021: 205 institutionsQ3 2021: 181 institutionsQ4 2021: 187 institutionsQ1 2022: 212 institutionsQ2 2022: 212 institutionsQ3 2022: 250 institutionsQ4 2022: 244 institutionsQ1 2023: 282 institutionsQ2 2023: 317 institutionsQ3 2023: 256 institutionsQ4 2023: 284 institutionsQ1 2024: 302 institutionsQ2 2024: 263 institutionsQ3 2024: 265 institutionsQ4 2024: 260 institutionsQ1 2025: 255 institutionsQ2 2025: 247 institutionsQ3 2025: 273 institutionsQ4 2025: 280 institutionsQ1 2026: 324 institutionsQ2 2026: 1 institution
Value heldQ1 2023: $7.28B
Q1 2021: $2.80BQ2 2021: $4.08BQ3 2021: $2.29BQ4 2021: $3.83BQ1 2022: $4.62BQ2 2022: $4.15BQ3 2022: $6.66BQ4 2022: $5.20BQ1 2023: $7.28BQ2 2023: $9.71BQ3 2023: $4.34BQ4 2023: $6.82BQ1 2024: $6.65BQ2 2024: $4.43BQ3 2024: $3.41BQ4 2024: $4.04BQ1 2025: $2.80BQ2 2025: $2.28BQ3 2025: $2.77BQ4 2025: $3.17BQ1 2026: $5.56BQ2 2026: $10.2K
Institutions holding APLS and their total value by quarter
QuarterHoldersValue
Q2 20261$10.2K
Q1 2026324$5.56B
Q4 2025280$3.17B
Q3 2025273$2.77B
Q2 2025247$2.28B
Q1 2025255$2.80B
Q4 2024260$4.04B
Q3 2024265$3.41B
Q2 2024263$4.43B
Q1 2024302$6.65B
Q4 2023284$6.82B
Q3 2023256$4.34B
Q2 2023317$9.71B
Q1 2023282$7.28B
Q4 2022244$5.20B
Q3 2022250$6.66B
Q2 2022212$4.15B
Q1 2022212$4.62B
Q4 2021187$3.83B
Q3 2021181$2.29B
Q2 2021205$4.08B
Q1 2021175$2.80B

Institutions, Q1 2023

Shares, value and share of portfolio for each institution holding Apellis Pharmaceuticals, Inc.; share changes are against Q4 2022.

Institutions holding APLS in Q1 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Allspring Global Investments Holdings, LLC130,911$8.63M0.01%+4,118+3.2%Added
Rhumbline Advisers130,961$8.64M0.01%+360+0.3%Added
Tekla Capital Management LLC135,124$8.91M0.34%+68,698+103.4%Added
Manufacturers Life Insurance Company, The136,596$9.01M0.01%+53,766+64.9%Added
Royal Bank of Canada137,243$9.05M0.00%+33,927+32.8%Added
Russell Investments Group, Ltd.138,200$9.12M0.02%+66,325+92.3%Added
Banque Pictet & Cie SA138,602$9.14M0.09%−20,323−12.8%Reduced
California Public Employees Retirement System142,006$9.37M0.01%−49,958−26.0%Reduced
Connor, Clark & Lunn Investment Management Ltd.151,995$10.0M0.05%+75,114+97.7%Added
683 Capital Management, LLC160,000$10.6M0.94%−15,000−8.6%Reduced
Granahan Investment Management Inc163,451$10.8M0.33%−19,057−10.4%Reduced
Ghost Tree Capital, LLC164,620$10.9M4.11%−135,380−45.1%Reduced
AXA S.A.171,109$11.3M0.04%+25,405+17.4%Added
Sectoral Asset Management Inc172,490$11.4M2.19%+20,150+13.2%Added
Citadel Advisors LLC174,060$11.5M0.01%+168,791+3,203.5%Added
Prudential Financial Inc177,339$11.7M0.02%−420.0%Reduced
Bleakley Financial Group, LLC181,877$12.0M0.40%−561−0.3%Reduced
Sawtooth Solutions, LLC181,877$12.0M0.31%+181,877New
Fred Alger Management, LLC182,244$12.0M0.06%−24,019−11.6%Reduced
Rhenman & Partners Asset Management AB185,000$12.2M1.34%−15,000−7.5%Reduced
Swiss National Bank191,000$12.6M0.01%−21,200−10.0%Reduced
Bank of Montreal206,548$13.9M0.01%+105,617+104.6%Added
Eagle Asset Management Inc229,382$15.1M0.09%+93,268+68.5%Added
American Century Companies Inc231,254$15.2M0.01%+430+0.2%Added
Barclays PLC242,181$16.0M0.02%+14,834+6.5%Added
New York State Common Retirement Fund243,120$16.0M0.02%+138,700+132.8%Added
Driehaus Capital Management LLC270,693$17.9M0.25%−22,852−7.8%Reduced
Voya Investment Management LLC279,186$18.4M0.02%+113,880+68.9%Added
Finepoint Capital LP283,690$18.7M7.15%−51,200−15.3%Reduced
PFM Health Sciences, LP284,269$18.8M0.86%−34,153−10.7%Reduced
Acuta Capital Partners, LLC290,500$19.2M14.91%+73,000+33.6%Added
Farallon Capital Management, L.L.C.317,553$20.9M0.13%−132,847−29.5%Reduced
Nicholas Investment Partners, LP336,951$22.2M1.69%+88,668+35.7%Added
Nuveen Asset Management, LLC349,554$23.1M0.01%−11,181−3.1%Reduced
Laurion Capital Management LP374,339$24.7M1.11%+374,339New
TD Asset Management Inc377,968$24.9M0.03%+106,348+39.2%Added
Bank of New York Mellon Corp392,396$25.9M0.01%−12,643−3.1%Reduced
Candriam Luxembourg S.C.A.443,507$26.9M0.19%+165,000+59.2%Added
D. E. Shaw & Co., Inc.412,853$27.2M0.04%+399,955+3,100.9%Added
Pictet Asset Management SA450,039$29.7M0.04%+4,334+1.0%Added
Polar Capital Holdings Plc465,000$30.7M0.22%+458,100+6,639.1%Added
Eventide Asset Management, LLC495,000$32.7M0.60%+155,645+45.9%Added
Federated Hermes, Inc.511,302$33.7M0.08%+75,002+17.2%Added
Fiera Capital Corp540,382$35.6M0.11%+540,382New
Fiduciary Trust Co542,291$35.8M0.66%−9,900−1.8%Reduced
Millennium Management LLC548,201$36.2M0.04%+528,565+2,691.8%Added
Perceptive Advisors LLC555,344$36.6M1.08%+555,344New
Victory Capital Management Inc562,169$37.1M0.04%+131,618+30.6%Added
Deutsche Bank AG599,428$39.5M0.02%+336,251+127.8%Added
Bank of America Corp607,735$40.1M0.00%+138,723+29.6%Added
Balyasny Asset Management LLC617,897$40.8M0.13%+361,556+141.0%Added
Goldman Sachs Group Inc663,195$43.7M0.01%−398,508−37.5%Reduced
Assenagon Asset Management S.A.743,246$49.0M0.19%+15,517+2.1%Added
Morgan Stanley752,862$49.7M0.01%+452,979+151.1%Added
Westfield Capital Management Co LP792,246$52.3M0.37%+102,769+14.9%Added
Logos Global Management LP800,000$52.8M7.55%−550,000−40.7%Reduced
Northern Trust Corp869,188$57.3M0.01%+12,067+1.4%Added
Lord, Abbett & Co. LLC904,228$59.6M0.22%−228,395−20.2%Reduced
OrbiMed Advisors LLC910,200$60.0M1.19%+910,200New
Norges Bank931,510$61.4M0.01%−115,944−11.1%Reduced
Charles Schwab Investment Management Inc983,509$64.9M0.02%+582+0.1%Added
Invesco Ltd.1,040,981$68.7M0.02%+540,194+107.9%Added
Bellevue Group AG1,109,382$73.2M1.06%+5,165+0.5%Added
Artal Group S.A.1,216,312$80.2M4.77%+316,312+35.1%Added
Cormorant Asset Management, LP1,360,000$89.7M5.91%−216,872−13.8%Reduced
Macquarie Group Ltd1,411,479$93.1M0.11%−50,163−3.4%Reduced
Boxer Capital, LLC1,576,000$104.0M5.11%00.0%Unchanged
JPMorgan Chase & Co1,648,452$108.7M0.01%−198,857−10.8%Reduced
Geode Capital Management, LLC1,838,279$121.3M0.02%+88,278+5.0%Added
Point72 Asset Management, L.P.1,879,724$124.0M0.44%+1,879,724New
FMR LLC2,125,437$140.2M0.01%+665,274+45.6%Added
Jennison Associates LLC2,612,767$172.3M0.16%+97,450+3.9%Added
State Street Corp2,979,862$196.6M0.01%−492,052−14.2%Reduced
Octagon Capital Advisors LP3,250,000$214.4M30.92%+90,000+2.8%Added
Price T Rowe Associates Inc4,590,040$302.8M0.05%+1,840,498+66.9%Added
Janus Henderson Group PLC4,681,482$308.8M0.20%+693,737+17.4%Added
EcoR1 Capital, LLC5,451,647$359.6M11.59%+268,216+5.2%Added
T. Rowe Price Investment Management, Inc.5,760,664$380.0M0.27%−81,996−1.4%Reduced
BlackRock Inc.7,655,451$505.0M0.01%−48,743−0.6%Reduced
Wellington Management Group LLP8,278,439$546.0M0.11%−479,222−5.5%Reduced
Vanguard Group Inc9,528,944$628.5M0.02%+316,453+3.4%Added
Avoro Capital Advisors LLC11,111,111$732.9M10.87%+486,111+4.6%Added
Braidwell LP0$00.00%−389,596−100.0%Sold out
Kynam Capital Management, LP0$00.00%−300,000−100.0%Sold out
Renaissance Technologies LLC0$00.00%−187,413−100.0%Sold out
Eversept Partners, LP0$00.00%−154,796−100.0%Sold out
Sessa Capital IM, L.P.0$00.00%−149,000−100.0%Sold out
Woodline Partners LP0$00.00%−70,651−100.0%Sold out
Nomura Holdings Inc0$00.00%−59,465−100.0%Sold out
DekaBank Deutsche Girozentrale0$00.00%−50,000−100.0%Sold out
Adage Capital Partners GP, L.L.C.0$00.00%−31,000−100.0%Sold out
Mirabella Financial Services LLP0$00.00%−25,326−100.0%Sold out
SG3 Management, LLC0$00.00%−22,000−100.0%Sold out
Caption Management, LLC0$00.00%−17,000−100.0%Sold out
DuPont Capital Management Corp0$00.00%−15,177−100.0%Sold out
Capital Fund Management S.A.0$00.00%−12,884−100.0%Sold out
Hillsdale Investment Management Inc.0$00.00%−12,600−100.0%Sold out
Duality Advisers, LP0$00.00%−11,823−100.0%Sold out
Harbour Capital Advisors, LLC0$00.00%−9,487−100.0%Sold out
Illinois Municipal Retirement Fund0$00.00%−8,694−100.0%Sold out