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Apellis Pharmaceuticals, Inc.

APLSDelisted May 14, 2026
Industry
Pharmaceutical Preparations
SEC CIK
0001492422

Apellis Pharmaceuticals, Inc. was delisted on May 14, 2026; its insiders filed their last Form 4 on May 14, 2026; 324 institutions reported holding it in 13F filings for Q1 2026, worth $5.56B in total; Soros Fund Management was the only superinvestor holding it.

13F holders, Q3 2021

Institutional positions in Apellis Pharmaceuticals, Inc. as of Sep 30, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
181
−21 vs. Q2 2021
Shares held
69.5M
+4.93M (+7.6%) vs. Q2 2021
Total value
$2.29B
−$1.79B (−43.9%) vs. Q2 2021
New holders
32
80 more added
Sold out
53
52 more reduced

3 institutions that held it in Q2 2021 haven't filed for Q3 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting APLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2021: 181 institutions
Q1 2021: 175 institutionsQ2 2021: 205 institutionsQ3 2021: 181 institutionsQ4 2021: 187 institutionsQ1 2022: 212 institutionsQ2 2022: 212 institutionsQ3 2022: 250 institutionsQ4 2022: 244 institutionsQ1 2023: 282 institutionsQ2 2023: 317 institutionsQ3 2023: 256 institutionsQ4 2023: 284 institutionsQ1 2024: 302 institutionsQ2 2024: 263 institutionsQ3 2024: 265 institutionsQ4 2024: 260 institutionsQ1 2025: 255 institutionsQ2 2025: 247 institutionsQ3 2025: 273 institutionsQ4 2025: 280 institutionsQ1 2026: 324 institutionsQ2 2026: 1 institution
Value heldQ3 2021: $2.29B
Q1 2021: $2.80BQ2 2021: $4.08BQ3 2021: $2.29BQ4 2021: $3.83BQ1 2022: $4.62BQ2 2022: $4.15BQ3 2022: $6.66BQ4 2022: $5.20BQ1 2023: $7.28BQ2 2023: $9.71BQ3 2023: $4.34BQ4 2023: $6.82BQ1 2024: $6.65BQ2 2024: $4.43BQ3 2024: $3.41BQ4 2024: $4.04BQ1 2025: $2.80BQ2 2025: $2.28BQ3 2025: $2.77BQ4 2025: $3.17BQ1 2026: $5.56BQ2 2026: $10.2K
Institutions holding APLS and their total value by quarter
QuarterHoldersValue
Q2 20261$10.2K
Q1 2026324$5.56B
Q4 2025280$3.17B
Q3 2025273$2.77B
Q2 2025247$2.28B
Q1 2025255$2.80B
Q4 2024260$4.04B
Q3 2024265$3.41B
Q2 2024263$4.43B
Q1 2024302$6.65B
Q4 2023284$6.82B
Q3 2023256$4.34B
Q2 2023317$9.71B
Q1 2023282$7.28B
Q4 2022244$5.20B
Q3 2022250$6.66B
Q2 2022212$4.15B
Q1 2022212$4.62B
Q4 2021187$3.83B
Q3 2021181$2.29B
Q2 2021205$4.08B
Q1 2021175$2.80B

Institutions, Q3 2021

Shares, value and share of portfolio for each institution holding Apellis Pharmaceuticals, Inc.; share changes are against Q2 2021.

Institutions holding APLS in Q3 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Citigroup Inc70,292$2.32M0.00%−22,436−24.2%Reduced
Acuta Capital Partners, LLC75,500$2.49M0.89%−85,000−53.0%Reduced
D. E. Shaw & Co., Inc.75,522$2.49M0.00%−169,507−69.2%Reduced
Connor, Clark & Lunn Investment Management Ltd.77,495$2.55M0.01%+59,074+320.7%Added
Alliancebernstein L.P.79,200$2.61M0.00%−900−1.1%Reduced
California State Teachers Retirement System84,617$2.79M0.00%−4,905−5.5%Reduced
Rafferty Asset Management, LLC89,199$2.94M0.02%+47,208+112.4%Added
State of Wisconsin Investment Board90,000$2.97M0.01%+9,100+11.2%Added
Royal Bank of Canada91,881$3.03M0.00%+6,232+7.3%Added
SG3 Management, LLC100,000$3.30M1.17%+90,000+900.0%Added
Kingdon Capital Management, L.L.C.100,000$3.30M0.58%+100,000New
Cutler Group LP101,785$3.35M0.25%+98,985+3,535.2%Added
Group One Trading, L.P.105,752$3.49M0.08%+105,752New
Alps Advisors Inc106,632$3.52M0.03%+1,008+1.0%Added
Woodline Partners LP108,076$3.56M0.06%+108,076New
Susquehanna International Group, LLP109,410$3.61M0.00%+80,641+280.3%Added
Duality Advisers, LP111,100$3.66M0.28%+111,100New
TD Asset Management Inc119,664$3.94M0.00%−19,738−14.2%Reduced
LMR Partners LLP121,111$3.99M0.06%+121,111New
Russell Investments Group, Ltd.124,434$4.10M0.01%+48,126+63.1%Added
Teachers Retirement System of the State of Kentucky131,190$4.32M0.04%+14,562+12.5%Added
Swiss National Bank133,400$4.40M0.00%+500+0.4%Added
Clough Capital Partners L P137,749$4.54M0.28%00.0%Unchanged
Private Advisor Group, LLC145,868$4.81M0.03%+74,673+104.9%Added
Tudor Investment Corp Et Al150,703$4.97M0.10%+128,065+565.7%Added
Pier Capital, LLC156,031$5.14M0.53%+156,031New
Jefferies Group LLC165,038$5.44M0.13%−344,091−67.6%Reduced
Prudential Financial Inc171,395$5.65M0.01%−12,745−6.9%Reduced
Morgan Stanley177,296$5.84M0.00%−52,045−22.7%Reduced
Hennion & Walsh Asset Management, Inc.182,205$6.00M0.32%−6,451−3.4%Reduced
Balyasny Asset Management LLC183,147$6.04M0.03%+183,147New
SG Americas Securities, LLC184,014$6.07M0.03%+159,061+637.4%Added
Integral Health Asset Management, LLC190,000$6.26M1.80%+155,000+442.9%Added
Tekla Capital Management LLC195,820$6.45M0.21%+43,282+28.4%Added
UBS Group AG196,882$6.49M0.00%+140,763+250.8%Added
Ghost Tree Capital, LLC200,000$6.59M2.17%+200,000New
Ameriprise Financial Inc202,712$6.68M0.00%+68,555+51.1%Added
UBS Asset Management Americas Inc203,990$6.72M0.00%−8,525−4.0%Reduced
Lombard Odier Asset Management (Switzerland) SA206,746$6.81M0.42%−188,287−47.7%Reduced
Natixis216,500$7.14M0.02%+107,300+98.3%Added
Candriam Luxembourg S.C.A.255,030$8.40M0.06%−62,285−19.6%Reduced
Bank of Montreal253,528$8.61M0.00%−965−0.4%Reduced
Bank of New York Mellon Corp269,484$8.88M0.00%+7,456+2.8%Added
Driehaus Capital Management LLC275,552$9.08M0.11%+16,159+6.2%Added
Frontier Capital Management Co LLC275,910$9.09M0.07%+98,385+55.4%Added
Nuveen Asset Management, LLC266,244$9.11M0.00%−64,935−19.6%Reduced
Bank of America Corp279,972$9.23M0.00%+39,593+16.5%Added
Nomura Holdings Inc284,500$9.56M0.07%+238,000+511.8%Added
Deutsche Bank AG291,009$9.59M0.00%−28,952−9.0%Reduced
Ikarian Capital, LLC347,545$11.5M2.62%+347,545New
Voloridge Investment Management, LLC348,708$11.5M0.07%+193,909+125.3%Added
Two Sigma Investments, LP362,204$11.9M0.03%−112,834−23.8%Reduced
Millennium Management LLC405,382$13.4M0.02%+405,382New
Arrowstreet Capital, Limited Partnership418,539$13.8M0.02%+297,251+245.1%Added
Two Sigma Advisers, LP491,600$16.2M0.04%−132,300−21.2%Reduced
Norges Bank510,178$16.8M0.00%+68,317+15.5%Added
Jacobs Levy Equity Management, Inc513,641$16.9M0.11%+390,616+317.5%Added
Charles Schwab Investment Management Inc518,811$17.1M0.01%+100,145+23.9%Added
Rhenman & Partners Asset Management AB561,269$18.5M1.30%+256,269+84.0%Added
Fiduciary Trust Co564,876$18.6M0.33%+926+0.2%Added
Franklin Resources Inc610,339$20.1M0.01%+610,339New
Perceptive Advisors LLC615,000$20.3M0.30%−46,162−7.0%Reduced
AJU IB Investment Co., Ltd.624,962$20.6M13.29%−440,000−41.3%Reduced
Northern Trust Corp662,686$21.8M0.00%−11,811−1.8%Reduced
Cormorant Asset Management, LP925,000$30.5M1.24%+75,000+8.8%Added
Goldman Sachs Group Inc1,023,170$33.7M0.01%+329,130+47.4%Added
Macquarie Group Ltd1,120,090$36.9M0.03%+574,416+105.3%Added
Geode Capital Management, LLC1,188,392$39.2M0.01%+70,257+6.3%Added
Logos Global Management LP1,450,000$47.8M3.45%+1,100,000+314.3%Added
JPMorgan Chase & Co1,533,142$50.5M0.01%+1,118,049+269.3%Added
Octagon Capital Advisors LP1,595,911$52.6M12.95%+339,646+27.0%Added
FMR LLC1,614,859$53.2M0.00%+143,694+9.8%Added
Victory Capital Management Inc1,770,807$58.4M0.06%+114,519+6.9%Added
Citadel Advisors LLC1,858,432$61.3M0.07%+1,505,416+426.4%Added
Jennison Associates LLC2,078,845$68.5M0.04%−370,679−15.1%Reduced
State Street Corp2,826,195$93.2M0.00%+879,227+45.2%Added
Price T Rowe Associates Inc4,807,077$158.4M0.01%−363,417−7.0%Reduced
Avoro Capital Advisors LLC5,000,000$164.8M2.59%+3,994,770+397.4%Added
BlackRock Inc.5,466,191$180.2M0.01%−204,541−3.6%Reduced
Vanguard Group Inc6,752,285$222.6M0.01%+407,829+6.4%Added
Wellington Management Group LLP11,171,572$368.2M0.06%+457,747+4.3%Added
HHLR Advisors, Ltd.SuperinvestorHHLR Advisors (Hillhouse)0$00.00%−2,929,708−100.0%Sold out
Baker Bros. Advisors LP0$00.00%−2,271,917−100.0%Sold out
Farallon Capital Management, L.L.C.0$00.00%−1,550,000−100.0%Sold out
venBio Partners LLC0$00.00%−411,471−100.0%Sold out
FIL Ltd0$00.00%−309,031−100.0%Sold out
Assenagon Asset Management S.A.0$00.00%−235,775−100.0%Sold out
Lisanti Capital Growth, LLC0$00.00%−119,445−100.0%Sold out
Bridger Management, LLC0$00.00%−116,015−100.0%Sold out
Ally Bridge Group (NY) LLC0$00.00%−85,000−100.0%Sold out
AXA S.A.0$00.00%−41,321−100.0%Sold out
EAM Investors, LLC0$00.00%−35,746−100.0%Sold out
Allianz Asset Management GmbH0$00.00%−26,240−100.0%Sold out
International Biotechnology Trust PLC0$00.00%−23,400−100.0%Sold out
Kiwi Wealth Investments Limited Partnership0$00.00%−23,201−100.0%Sold out
Renaissance Technologies LLC0$00.00%−20,211−100.0%Sold out
SEI Investments Co0$00.00%−19,674−100.0%Sold out
Verition Fund Management LLC0$00.00%−19,477−100.0%Sold out
Gsa Capital Partners LLP0$00.00%−17,447−100.0%Sold out
ETF Managers Group, LLC0$00.00%−12,899−100.0%Sold out