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Alnylam Pharmaceuticals, Inc.

ALNY
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001178670

No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Alnylam Pharmaceuticals, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
852
+55 vs. Q3 2025
Shares held
132.8M
+3.06M (+2.4%) vs. Q3 2025
Total value
$52.7B
−$6.43B (−10.9%) vs. Q3 2025
New holders
172
290 more added
Sold out
117
291 more reduced

26 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 852 institutions
Q1 2021: 391 institutionsQ2 2021: 401 institutionsQ3 2021: 407 institutionsQ4 2021: 435 institutionsQ1 2022: 443 institutionsQ2 2022: 424 institutionsQ3 2022: 497 institutionsQ4 2022: 489 institutionsQ1 2023: 478 institutionsQ2 2023: 477 institutionsQ3 2023: 454 institutionsQ4 2023: 501 institutionsQ1 2024: 499 institutionsQ2 2024: 525 institutionsQ3 2024: 569 institutionsQ4 2024: 594 institutionsQ1 2025: 625 institutionsQ2 2025: 653 institutionsQ3 2025: 823 institutionsQ4 2025: 852 institutionsQ1 2026: 793 institutionsQ2 2026: 794 institutions
Value heldQ4 2025: $52.7B
Q1 2021: $15.4BQ2 2021: $19.0BQ3 2021: $21.1BQ4 2021: $19.0BQ1 2022: $18.6BQ2 2022: $16.6BQ3 2022: $26.7BQ4 2022: $28.4BQ1 2023: $24.0BQ2 2023: $22.5BQ3 2023: $20.9BQ4 2023: $22.4BQ1 2024: $17.2BQ2 2024: $29.1BQ3 2024: $34.1BQ4 2024: $30.1BQ1 2025: $34.8BQ2 2025: $43.1BQ3 2025: $59.2BQ4 2025: $52.7BQ1 2026: $43.4BQ2 2026: $40.1B
Institutions holding ALNY and their total value by quarter
QuarterHoldersValue
Q2 2026794$40.1B
Q1 2026793$43.4B
Q4 2025852$52.7B
Q3 2025823$59.2B
Q2 2025653$43.1B
Q1 2025625$34.8B
Q4 2024594$30.1B
Q3 2024569$34.1B
Q2 2024525$29.1B
Q1 2024499$17.2B
Q4 2023501$22.4B
Q3 2023454$20.9B
Q2 2023477$22.5B
Q1 2023478$24.0B
Q4 2022489$28.4B
Q3 2022497$26.7B
Q2 2022424$16.6B
Q1 2022443$18.6B
Q4 2021435$19.0B
Q3 2021407$21.1B
Q2 2021401$19.0B
Q1 2021391$15.4B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q3 2025.

Institutions holding ALNY in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Colonial Trust Co99$39.4K0.01%+61+160.5%Added
Parkside Financial Bank & Trust97$38.6K0.00%−82−45.8%Reduced
Elequin Capital LP97$38.6K0.01%+97New
Westside Investment Management, Inc.96$38.4K0.01%00.0%Unchanged
Quent Capital, LLC94$37.4K0.00%+9+10.6%Added
Manchester Capital Management LLC84$33.4K0.00%+72+600.0%Added
Whittier Trust Co of Nevada Inc82$33.3K0.00%−33−28.7%Reduced
Cornerstone Planning Group LLC95$33.2K0.01%−397−80.7%Reduced
Hilltop National Bank80$31.8K0.01%−11−12.1%Reduced
ORG Partners LLC73$29.0K0.01%−7−8.8%Reduced
TFC Financial Management72$28.6K0.00%−2−2.7%Reduced
Golden State Wealth Management, LLC72$28.6K0.00%+36+100.0%Added
Whittier Trust Co69$28.0K0.00%00.0%Unchanged
HM Payson & Co68$27.0K0.00%+68New
MV Capital Management, Inc.63$25.1K0.00%−1−1.6%Reduced
Covestor Ltd63$25.0K0.01%−209−76.8%Reduced
Private Wealth Management Group, LLC62$24.7K0.01%00.0%Unchanged
Root Financial Partners, LLC62$24.7K0.00%+8+14.8%Added
Truvestments Capital LLC60$23.9K0.00%+3+5.3%Added
Global Trust Asset Management, LLC60$23.9K0.01%00.0%Unchanged
CVA Family Office, LLC59$23.5K0.00%−3−4.8%Reduced
Sound Income Strategies, LLC61$21.9K0.00%+61New
Kemnay Advisory Services Inc.52$20.7K0.00%+52New
Rachor Investment Advisory Services, LLC51$20.3K0.01%+51New
Generali Asset Management SPA SGR50$19.9K0.00%−3,184−98.5%Reduced
St. Johns Investment Management Company, LLC50$19.9K0.01%00.0%Unchanged
Peoples Financial Services Corp.50$19.9K0.01%00.0%Unchanged
Piscataqua Savings Bank50$19.9K0.01%00.0%Unchanged
Pinnacle Wealth Planning Services, Inc.49$19.3K0.00%+49New
JFS Wealth Advisors, LLC45$17.9K0.00%+10+28.6%Added
Private Wealth Asset Management, LLC42$16.7K0.00%00.0%Unchanged
MidFirst Bank541$16.3K0.00%+541New
Millstone Evans Group, LLC40$15.9K0.01%00.0%Unchanged
Aventura Private Wealth, LLC40$15.9K0.01%00.0%Unchanged
Cape Investment Advisory, Inc.39$15.5K0.00%−69−63.9%Reduced
Bell Investment Advisors, Inc36$14.3K0.00%00.0%Unchanged
SOA Wealth Advisors, LLC.36$14.3K0.00%00.0%Unchanged
Bogart Wealth, LLC36$14.3K0.00%+1+2.9%Added
SJS Investment Consulting Inc.35$13.9K0.00%+33+1,650.0%Added
Sachetta, LLC33$13.1K0.01%−40−54.8%Reduced
Avion Wealth33$13.0K0.00%−4−10.8%Reduced
Godsey & Gibb Associates32$12.7K0.00%+4+14.3%Added
FWL Investment Management, LLC31$12.3K0.00%00.0%Unchanged
WPG Advisers, LLC31$12.3K0.01%00.0%Unchanged
Dogwood Wealth Management LLC31$12.3K0.01%+11+55.0%Added
Swiss Re Ltd30$11.9K0.00%+30New
Private Trust Co NA28$11.1K0.00%−547−95.1%Reduced
UMA Financial Services, Inc.24$9.54K0.00%−7−22.6%Reduced
Salomon & Ludwin, LLC23$9.15K0.00%−37−61.7%Reduced
Proffitt & Goodson Inc23$9.15K0.00%−1−4.2%Reduced
TD Capital Management LLC23$9.15K0.00%00.0%Unchanged
Estate Planners Group, LLC23$9.15K0.00%+23New
Ancora Advisors, LLC22$8.75K0.00%+22New
Cromwell Holdings LLC20$7.95K0.00%00.0%Unchanged
Ares Financial Consulting, LLC20$7.95K0.01%+20New
TCTC Holdings, LLC19$7.55K0.00%00.0%Unchanged
Raffa Wealth Management, LLC18$7.16K0.00%+3+20.0%Added
Osbon Capital Management LLC18$7.16K0.01%+18New
Elyxium Wealth, LLC18$7.16K0.00%+18New
Wilkerson Advisory Group LLC17$6.76K0.00%+17New
Fourth Dimension Wealth, LLC16$6.36K0.00%−557−97.2%Reduced
Vermillion & White Wealth Management Group, LLC16$6.36K0.00%00.0%Unchanged
Cetera Trust Company, N.A16$6.36K0.00%00.0%Unchanged
Sunbelt Securities, Inc.15$5.96K0.00%00.0%Unchanged
Sherman Asset Management, Inc.15$5.96K0.01%00.0%Unchanged
Strategic Wealth Partners, Ltd.15$5.96K0.00%+15New
South State Corp.14$5.57K0.00%−6−30.0%Reduced
Trust Co of Vermont14$5.57K0.00%00.0%Unchanged
Umb Bank N A14$5.57K0.00%+2+16.7%Added
HighMark Wealth Management LLC14$5.57K0.00%+14New
Motco13$5.17K0.00%00.0%Unchanged
Chung Wu Investment Group, LLC13$5.17K0.00%00.0%Unchanged
Cornerstone Financial Management LLC13$5.17K0.00%+13New
Valley National Advisers Inc13$5.00K0.00%−2−13.3%Reduced
Accent Capital Management, LLC12$4.77K0.00%00.0%Unchanged
Hughes Financial Services, LLC12$4.77K0.00%00.0%Unchanged
S&T Bank11$4.37K0.00%−4−26.7%Reduced
Flagship Harbor Advisors, LLC11$4.37K0.00%+11New
Curio Wealth, LLC10$4.01K0.00%+10New
Mark Sheptoff Financial Planning, LLC10$3.98K0.00%00.0%Unchanged
Archer Investment Corp10$3.98K0.00%00.0%Unchanged
Tripletail Wealth Management, LLC10$3.98K0.01%00.0%Unchanged
Toth Financial Advisory Corp10$3.98K0.00%+1+11.1%Added
HFM Investment Advisors, LLC10$3.98K0.00%+9+900.0%Added
High Point Wealth Management, LLC10$3.98K0.00%+10New
Ameriflex Group, Inc.9$3.58K0.00%−61−87.1%Reduced
Grove Bank & Trust9$3.58K0.00%+9New
Bay Harbor Wealth Management, LLC9$3.58K0.00%+3+50.0%Added
Washington Trust Advisors, Inc.9$3.42K0.00%+1+12.5%Added
DiNuzzo Private Wealth, Inc.8$3.18K0.00%00.0%Unchanged
First Pacific Financial8$3.18K0.00%+8New
NBC Securities, Inc.8$3.18K0.00%−4−33.3%Reduced
Highline Wealth Partners LLC8$3.18K0.00%00.0%Unchanged
Signature Resources Capital Management, LLC8$3.18K0.00%+8New
Penserra Capital Management LLC9$3.00K0.00%00.0%Unchanged
Motiv8 Investments LLC7$3.00K0.00%+7New
Johnson Financial Group, Inc.7$2.78K0.00%−5−41.7%Reduced
Front Row Advisors LLC7$2.78K0.00%00.0%Unchanged
City Holding Co7$2.78K0.00%00.0%Unchanged
AdvisorNet Financial, Inc6$2.39K0.00%−15−71.4%Reduced