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Alnylam Pharmaceuticals, Inc.

ALNY
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001178670

No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.

13F holders, Q1 2025

Institutional positions in Alnylam Pharmaceuticals, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
625
+39 vs. Q4 2024
Shares held
129.4M
+2.10M (+1.7%) vs. Q4 2024
Total value
$34.8B
+$4.88B (+16.3%) vs. Q4 2024
New holders
106
235 more added
Sold out
67
205 more reduced

8 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 625 institutions
Q1 2021: 391 institutionsQ2 2021: 401 institutionsQ3 2021: 407 institutionsQ4 2021: 435 institutionsQ1 2022: 443 institutionsQ2 2022: 424 institutionsQ3 2022: 497 institutionsQ4 2022: 489 institutionsQ1 2023: 478 institutionsQ2 2023: 477 institutionsQ3 2023: 454 institutionsQ4 2023: 501 institutionsQ1 2024: 499 institutionsQ2 2024: 525 institutionsQ3 2024: 569 institutionsQ4 2024: 594 institutionsQ1 2025: 625 institutionsQ2 2025: 653 institutionsQ3 2025: 823 institutionsQ4 2025: 852 institutionsQ1 2026: 793 institutionsQ2 2026: 794 institutions
Value heldQ1 2025: $34.8B
Q1 2021: $15.4BQ2 2021: $19.0BQ3 2021: $21.1BQ4 2021: $19.0BQ1 2022: $18.6BQ2 2022: $16.6BQ3 2022: $26.7BQ4 2022: $28.4BQ1 2023: $24.0BQ2 2023: $22.5BQ3 2023: $20.9BQ4 2023: $22.4BQ1 2024: $17.2BQ2 2024: $29.1BQ3 2024: $34.1BQ4 2024: $30.1BQ1 2025: $34.8BQ2 2025: $43.1BQ3 2025: $59.2BQ4 2025: $52.7BQ1 2026: $43.4BQ2 2026: $40.1B
Institutions holding ALNY and their total value by quarter
QuarterHoldersValue
Q2 2026794$40.1B
Q1 2026793$43.4B
Q4 2025852$52.7B
Q3 2025823$59.2B
Q2 2025653$43.1B
Q1 2025625$34.8B
Q4 2024594$30.1B
Q3 2024569$34.1B
Q2 2024525$29.1B
Q1 2024499$17.2B
Q4 2023501$22.4B
Q3 2023454$20.9B
Q2 2023477$22.5B
Q1 2023478$24.0B
Q4 2022489$28.4B
Q3 2022497$26.7B
Q2 2022424$16.6B
Q1 2022443$18.6B
Q4 2021435$19.0B
Q3 2021407$21.1B
Q2 2021401$19.0B
Q1 2021391$15.4B

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q4 2024.

Institutions holding ALNY in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Privium Fund Management B.V.5,716$1.54M0.40%+5,716New
Shell Asset Management Co5,655$1.53M0.07%−337−5.6%Reduced
Metis Global Partners, LLC5,566$1.50M0.04%+839+17.7%Added
CIBC Asset Management Inc5,422$1.46M0.00%+288+5.6%Added
Prelude Capital Management, LLC5,408$1.46M0.15%+595+12.4%Added
Knollwood Investment Advisory, LLC5,355$1.45M0.16%00.0%Unchanged
BI Asset Management Fondsmaeglerselskab A/S5,342$1.44M0.02%−6,413−54.6%Reduced
Merit Financial Group, LLC5,314$1.43M0.02%+2,819+113.0%Added
Sectoral Asset Management Inc5,205$1.41M1.09%−3,095−37.3%Reduced
Dark Forest Capital Management LP5,153$1.39M0.06%+5,153New
Westpac Banking Corp5,073$1.37M0.10%−5,487−52.0%Reduced
Plato Investment Management Ltd4,659$1.27M0.11%−888−16.0%Reduced
Allstate Corp4,701$1.27M0.04%+903+23.8%Added
US Bancorp4,590$1.24M0.00%−192−4.0%Reduced
Commerce Bank4,557$1.23M0.01%+55+1.2%Added
Omers Administration Corp4,517$1.22M0.01%−735−14.0%Reduced
Bank of Nova Scotia4,506$1.22M0.00%−6−0.1%Reduced
Brandywine Managers, LLC4,348$1.17M1.41%00.0%Unchanged
Citadel Advisors LLC4,236$1.14M0.00%−61,157−93.5%Reduced
Colony Group, LLC4,218$1.14M0.00%−209−4.7%Reduced
AustralianSuper Pty Ltd4,218$1.14M0.01%00.0%Unchanged
Atria Investments LLC4,204$1.14M0.01%+893+27.0%Added
RSM US Wealth Management LLC4,182$1.13M0.02%−566−11.9%Reduced
Arrowstreet Capital, Limited Partnership4,055$1.09M0.00%+4,055New
Howland Capital Management LLC4,000$1.08M0.05%00.0%Unchanged
J.P. Marvel Investment Advisors, LLC4,000$1.08M0.19%00.0%Unchanged
Morgens Waterfall Vintiadis & Co Inc4,000$1.08M1.22%+4,000New
Atlantic Trust, LLC3,992$1.08M0.24%+11+0.3%Added
Gilbert & Cook, Inc.3,904$1.05M0.15%00.0%Unchanged
Brinker Capital Investments, LLC3,857$1.04M0.01%+113+3.0%Added
Orion Portfolio Solutions, LLC3,857$1.04M0.01%+113+3.0%Added
O'Shaughnessy Asset Management, LLC3,803$1.03M0.01%+360+10.5%Added
Point72 Hong Kong Ltd3,795$1.02M0.07%+3,795New
Kentucky Retirement Systems Insurance Trust Fund3,746$1.01M0.07%+3,746New
Banque Cantonale Vaudoise3,728$1.01M0.04%+3,728New
Y-Intercept (Hong Kong) Ltd3,720$1.00M0.07%−796−17.6%Reduced
Perpetual Ltd3,718$1.00M0.01%−5,213−58.4%Reduced
Exchange Traded Concepts, LLC3,715$1.00M0.02%−118−3.1%Reduced
Truist Financial Corp3,624$978.6K0.00%−774−17.6%Reduced
Rakuten Investment Management, Inc.3,559$955.4K0.00%+3,559New
Sequoia Financial Advisors, LLC3,395$916.8K0.01%+99+3.0%Added
Tobam3,366$909.0K0.39%−8,418−71.4%Reduced
Walleye Trading LLC3,360$907.3K0.03%+3,360New
Spectrum Planning & Advisory Services Inc.3,359$907.0K0.75%00.0%Unchanged
Orion Capital Management LLC3,340$901.9K0.38%00.0%Unchanged
Sanders Morris Harris LLC3,500$895.2K0.14%00.0%Unchanged
GF Fund Management Co. Ltd.3,302$891.6K0.02%+594+21.9%Added
Sanctuary Advisors, LLC3,290$888.4K0.01%−1,625−33.1%Reduced
Credit Agricole S A3,287$887.6K0.00%−706−17.7%Reduced
Hall Laurie J Trustee3,250$877.6K0.31%00.0%Unchanged
B. Metzler seel. Sohn & Co. AG3,233$873.0K0.01%−46−1.4%Reduced
Mercer Global Advisors Inc3,210$866.7K0.00%+610+23.5%Added
Summit Global Investments3,145$849.0K0.06%+3,145New
Schonfeld Strategic Advisors LLC3,082$832.2K0.01%−123,918−97.6%Reduced
Persistent Asset Partners Ltd3,034$819.2K0.72%+3,034New
Grandfield & Dodd, LLC3,032$818.7K0.05%+659+27.8%Added
Everence Capital Management Inc2,970$802.0K0.05%+450+17.9%Added
Regal Investment Advisors LLC2,906$784.7K0.06%−252−8.0%Reduced
Generali Investments CEE, investicni spolecnost, a.s.2,900$783.1K0.07%00.0%Unchanged
Horizon Kinetics Asset Management LLC2,880$777.7K0.01%00.0%Unchanged
Keybank National Association2,794$754.4K0.00%−68−2.4%Reduced
Greenleaf Trust2,750$742.6K0.01%+28+1.0%Added
Integrated Wealth Concepts LLC2,739$739.6K0.01%+227+9.0%Added
Shepherd Financial Partners LLC2,736$738.8K0.09%00.0%Unchanged
Bannerman Wealth Management Group, LLC2,729$736.9K0.60%+1,338+96.2%Added
Steel Peak Wealth Management LLC2,727$736.2K0.03%−753−21.6%Reduced
Buckingham Strategic Partners2,724$735.5K0.01%+1,862+216.0%Added
Vident Advisory, LLC2,667$720.1K0.01%+1,340+101.0%Added
Central Pacific Bank - Trust Division2,653$716.4K0.10%+1,648+164.0%Added
UniSuper Management Pty Ltd2,500$675.0K0.01%00.0%Unchanged
Vestcor Inc2,461$665.0K0.02%+6+0.2%Added
Wolverine Trading, LLC2,438$654.5K0.02%−4,885−66.7%Reduced
Walleye Capital LLC2,370$639.9K0.01%−17,746−88.2%Reduced
EntryPoint Capital, LLC2,364$638.3K0.29%−178−7.0%Reduced
Kovitz Investment Group Partners, LLC2,349$634.2K0.00%−292−11.1%Reduced
PEAK6 LLC2,295$619.7K0.02%−8,407−78.6%Reduced
Nixon Peabody Trust Co2,277$614.8K0.05%−16−0.7%Reduced
Aster Capital Management (DIFC) Ltd2,451$604.8K0.11%+2,451New
Ci Investments Inc.2,221$600.0K0.00%−1,263−36.3%Reduced
New York Life Investment Management LLC2,214$597.8K0.01%−170−7.1%Reduced
Accurate Wealth Management, LLC2,483$590.4K0.11%+2,483New
Corebridge Financial, Inc.2,128$574.6K0.00%−81−3.7%Reduced
Monograph Wealth Advisors, LLC2,126$574.1K0.08%−12−0.6%Reduced
GraniteShares Advisors LLC2,110$569.7K0.36%−155−6.8%Reduced
Sava Infond d.o.o.2,080$561.6K0.11%+350+20.2%Added
Prudential PLC2,047$552.7K0.00%−2,233−52.2%Reduced
Archford Capital Strategies, LLC2,019$545.2K0.08%+2,019New
Security National Bank of So Dak2,000$540.0K0.31%00.0%Unchanged
Kornitzer Capital Management Inc2,000$540.0K0.01%+2,000New
Meiji Yasuda Asset Management Co Ltd.1,986$536.3K0.02%00.0%Unchanged
QRG Capital Management, Inc.1,949$526.3K0.01%+964+97.9%Added
Ethic Inc.2,043$522.6K0.01%−2,843−58.2%Reduced
Graham Capital Management, L.P.1,910$515.7K0.02%−440−18.7%Reduced
Capital Group Private Client Services, Inc.1,856$501.2K0.00%−39,669−95.5%Reduced
Summit Trail Advisors, LLC1,803$486.8K0.02%+518+40.3%Added
Souders Financial Advisors1,793$484.1K0.07%−947−34.6%Reduced
Everhart Financial Group, Inc.1,787$482.5K0.07%+191+12.0%Added
S-Bank Fund Management Ltd1,760$475.2K0.09%+1,760New
Signaturefd, LLC1,755$473.9K0.01%+115+7.0%Added
Oppenheimer & Co Inc1,716$463.4K0.01%00.0%Unchanged