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Alnylam Pharmaceuticals, Inc.

ALNY
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001178670

No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.

13F holders, Q1 2025

Institutional positions in Alnylam Pharmaceuticals, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
625
+39 vs. Q4 2024
Shares held
129.4M
+2.10M (+1.7%) vs. Q4 2024
Total value
$34.8B
+$4.88B (+16.3%) vs. Q4 2024
New holders
106
235 more added
Sold out
67
205 more reduced

8 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 625 institutions
Q1 2021: 391 institutionsQ2 2021: 401 institutionsQ3 2021: 407 institutionsQ4 2021: 435 institutionsQ1 2022: 443 institutionsQ2 2022: 424 institutionsQ3 2022: 497 institutionsQ4 2022: 489 institutionsQ1 2023: 478 institutionsQ2 2023: 477 institutionsQ3 2023: 454 institutionsQ4 2023: 501 institutionsQ1 2024: 499 institutionsQ2 2024: 525 institutionsQ3 2024: 569 institutionsQ4 2024: 594 institutionsQ1 2025: 625 institutionsQ2 2025: 653 institutionsQ3 2025: 823 institutionsQ4 2025: 852 institutionsQ1 2026: 793 institutionsQ2 2026: 794 institutions
Value heldQ1 2025: $34.8B
Q1 2021: $15.4BQ2 2021: $19.0BQ3 2021: $21.1BQ4 2021: $19.0BQ1 2022: $18.6BQ2 2022: $16.6BQ3 2022: $26.7BQ4 2022: $28.4BQ1 2023: $24.0BQ2 2023: $22.5BQ3 2023: $20.9BQ4 2023: $22.4BQ1 2024: $17.2BQ2 2024: $29.1BQ3 2024: $34.1BQ4 2024: $30.1BQ1 2025: $34.8BQ2 2025: $43.1BQ3 2025: $59.2BQ4 2025: $52.7BQ1 2026: $43.4BQ2 2026: $40.1B
Institutions holding ALNY and their total value by quarter
QuarterHoldersValue
Q2 2026794$40.1B
Q1 2026793$43.4B
Q4 2025852$52.7B
Q3 2025823$59.2B
Q2 2025653$43.1B
Q1 2025625$34.8B
Q4 2024594$30.1B
Q3 2024569$34.1B
Q2 2024525$29.1B
Q1 2024499$17.2B
Q4 2023501$22.4B
Q3 2023454$20.9B
Q2 2023477$22.5B
Q1 2023478$24.0B
Q4 2022489$28.4B
Q3 2022497$26.7B
Q2 2022424$16.6B
Q1 2022443$18.6B
Q4 2021435$19.0B
Q3 2021407$21.1B
Q2 2021401$19.0B
Q1 2021391$15.4B

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q4 2024.

Institutions holding ALNY in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Point72 (DIFC) Ltd1,712$462.2K0.04%+1,712New
Lecap Asset Management Ltd1,709$461.5K0.11%+1,709New
Fort Sheridan Advisors LLC1,701$459.3K0.07%00.0%Unchanged
Vontobel Holding Ltd.1,691$456.6K0.00%−113−6.3%Reduced
Beacon Investment Advisory Services, Inc.1,688$455.8K0.02%−2,033−54.6%Reduced
New York State Teachers Retirement System1,678$453.0K0.00%−4,158−71.2%Reduced
Yousif Capital Management, LLC1,673$451.7K0.01%+31+1.9%Added
Advisor Group Holdings, Inc.1,629$440.0K0.00%−3,200−66.3%Reduced
Ballentine Partners, LLC1,625$438.8K0.01%+52+3.3%Added
Kennedy Capital Management, Inc.1,541$416.1K0.01%+6+0.4%Added
United Capital Financial Advisers, LLC1,532$413.7K0.00%+52+3.5%Added
High Net Worth Advisory Group LLC1,500$405.0K0.11%00.0%Unchanged
Emerald Advisers, LLC1,496$403.9K0.02%−84−5.3%Reduced
XTX Topco Ltd1,488$401.8K0.02%+1,488New
Banque Pictet & Cie SA1,483$400.4K0.00%+1,483New
Diversified Trust Co1,482$400.2K0.01%−999−40.3%Reduced
Siemens Fonds Invest GmbH1,471$397.2K0.03%+106+7.8%Added
Virtus Investment Advisers, Inc.1,467$396.1K0.11%+1,467New
Asahi Life Asset Management Co., Ltd.1,440$388.8K0.25%−40−2.7%Reduced
Forum Financial Management, LP1,427$385.3K0.01%−37−2.5%Reduced
Wedmont Private Capital1,592$378.5K0.02%+107+7.2%Added
Yarbrough Capital, LLC1,376$371.5K0.02%00.0%Unchanged
Fulton Bank, N.A.1,375$371.3K0.01%+32+2.4%Added
Loring Wolcott & Coolidge Fiduciary Advisors LLP1,533$370.9K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)1,383$366.6K0.01%−3,998−74.3%Reduced
Allegiance Financial Group Advisory Services LLC1,353$365.3K0.11%+384+39.6%Added
Ontario Teachers Pension Plan Board1,345$363.2K0.01%−202−13.1%Reduced
Inceptionr LLC1,338$361.3K0.11%+1,338New
Ossiam1,336$360.7K0.01%−1,091−45.0%Reduced
Abn Amro Investment Solutions1,310$353.7K0.01%+99+8.2%Added
North Star Asset Management Inc1,305$352.4K0.02%−5−0.4%Reduced
Clearstead Advisors, LLC1,304$352.1K0.01%+194+17.5%Added
Kaufman Rossin Wealth, LLC1,300$351.0K0.25%+1,300New
Cigna Investments Inc1,297$351.0K0.07%00.0%Unchanged
Plante Moran Financial Advisors, LLC1,285$347.0K0.03%+650+102.4%Added
Crowley Wealth Management, Inc.1,250$337.5K0.32%00.0%Unchanged
Penserra Capital Management LLC1,220$329.0K0.01%+1,208+10,066.7%Added
Resources Investment Advisors, LLC.1,211$327.0K0.00%+165+15.8%Added
Brighton Jones LLC1,209$326.5K0.01%+177+17.2%Added
NorthCrest Asset Manangement, LLC1,196$323.0K0.01%+1,196New
Qsemble Capital Management, LP1,196$322.9K0.03%+1,196New
Marex Group plc1,173$316.7K0.01%−95−7.5%Reduced
Towarzystwo Funduszy Inwestycyjnych Pzu SA1,162$313.8K0.11%+160+16.0%Added
Two Sigma Securities, LLC1,159$313.0K0.05%+42+3.8%Added
Ronald Blue Trust, Inc.1,158$312.7K0.00%+293+33.9%Added
Algert Global LLC1,150$310.5K0.01%+1,150New
Peregrine Capital Management LLC1,147$309.7K0.01%00.0%Unchanged
Bryn Mawr Trust Co1,098$296.5K0.01%+1,089+12,100.0%Added
Coldstream Capital Management Inc1,079$291.3K0.01%−34−3.1%Reduced
Steward Partners Investment Advisory, LLC1,062$286.8K0.00%+122+13.0%Added
TownSquare Capital, LLC1,059$285.9K0.00%+93+9.6%Added
Altfest L J & Co Inc1,050$283.5K0.04%+1,050New
Nichols & Pratt Advisers LLP1,043$281.6K0.02%−332−24.1%Reduced
Principal Securities, Inc.1,187$279.3K0.01%00.0%Unchanged
Breakwater Capital Group1,029$277.9K0.05%00.0%Unchanged
Eqis Capital Management, Inc.1,028$277.6K0.02%−141−12.1%Reduced
Callan Family Office, LLC1,018$274.9K0.02%−24−2.3%Reduced
Crossmark Global Holdings, Inc.1,018$274.9K0.00%+1,018New
Sym Financial Corp1,014$273.8K0.03%+51+5.3%Added
Greenland Capital Management LP1,000$270.0K0.05%−1,000−50.0%Reduced
Westmount Partners, LLC1,000$270.0K0.08%00.0%Unchanged
Livforsakringsbolaget Skandia, Omsesidigt1,000$269.9K0.02%00.0%Unchanged
EP Wealth Advisors, LLC998$269.4K0.00%+998New
Sara-Bay Financial1,000$268.5K0.12%+15+1.5%Added
Meeder Advisory Services, Inc.978$264.1K0.02%+72+7.9%Added
Polymer Capital Management (US) LLC961$259.5K0.08%+961New
Kestra Advisory Services, LLC958$258.7K0.00%−629−39.6%Reduced
Dai-Ichi Life Insurance Company, Ltd955$257.9K0.01%00.0%Unchanged
HCR Wealth Advisors924$249.5K0.03%00.0%Unchanged
Fukoku Mutual Life Insurance Co914$246.8K0.02%00.0%Unchanged
Nwam LLC907$244.9K0.02%+1+0.1%Added
Independent Financial Group, LLC890$240.3K0.01%−15−1.7%Reduced
Smartleaf Asset Management LLC895$240.3K0.02%+148+19.8%Added
Envestnet Portfolio Solutions, Inc.867$234.1K0.00%−1,195−58.0%Reduced
Beacon Pointe Advisors, LLC867$234.1K0.00%−68−7.3%Reduced
Parallel Advisors, LLC862$232.7K0.01%+31+3.7%Added
Poinciana Advisors Group, LLC851$229.8K0.24%−10−1.2%Reduced
Snowden Capital Advisors LLC829$223.8K0.01%+829New
Wiley Bros.-Aintree Capital, LLC828$222.9K0.00%+828New
Chapin Davis, Inc.825$222.8K0.08%00.0%Unchanged
Proficio Capital Partners LLC808$218.2K0.02%+808New
Meridian Financial, LLC800$216.0K0.15%−100−11.1%Reduced
Compass Capital Corp800$215.0K0.11%00.0%Unchanged
Cambridge Investment Research Advisors, Inc.789$213.0K0.00%+789New
Essex LLC788$212.8K0.05%+788New
Ellevest, Inc.773$208.7K0.01%−651−45.7%Reduced
HB Wealth Management, LLC771$208.3K0.00%+771New
Alta Advisers Ltd757$204.4K0.09%+757New
Strategic Financial Concepts, LLC752$203.1K0.04%+752New
Ascent Group, LLC749$202.2K0.01%+749New
Parcion Private Wealth LLC748$202.0K0.02%+748New
National Bank of Canada663$179.0K0.00%−5−0.7%Reduced
Zions Bancorporation, National Association646$174.4K0.01%+646New
Caitong International Asset Management Co., Ltd618$166.9K0.12%+602+3,762.5%Added
GAMMA Investing LLC616$166.3K0.01%+77+14.3%Added
Lindbrook Capital, LLC596$160.9K0.01%+50+9.2%Added
Allworth Financial LP618$149.9K0.00%+21+3.5%Added
Quadrant Capital Group LLC548$148.0K0.01%+302+122.8%Added
Northwestern Mutual Wealth Management Co525$141.8K0.00%+49+10.3%Added
Fourth Dimension Wealth, LLC504$136.1K0.07%+504New