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Alnylam Pharmaceuticals, Inc.

ALNY
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001178670

No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.

13F holders, Q1 2025

Institutional positions in Alnylam Pharmaceuticals, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
625
+39 vs. Q4 2024
Shares held
129.4M
+2.10M (+1.7%) vs. Q4 2024
Total value
$34.8B
+$4.88B (+16.3%) vs. Q4 2024
New holders
106
235 more added
Sold out
67
205 more reduced

8 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 625 institutions
Q1 2021: 391 institutionsQ2 2021: 401 institutionsQ3 2021: 407 institutionsQ4 2021: 435 institutionsQ1 2022: 443 institutionsQ2 2022: 424 institutionsQ3 2022: 497 institutionsQ4 2022: 489 institutionsQ1 2023: 478 institutionsQ2 2023: 477 institutionsQ3 2023: 454 institutionsQ4 2023: 501 institutionsQ1 2024: 499 institutionsQ2 2024: 525 institutionsQ3 2024: 569 institutionsQ4 2024: 594 institutionsQ1 2025: 625 institutionsQ2 2025: 653 institutionsQ3 2025: 823 institutionsQ4 2025: 852 institutionsQ1 2026: 793 institutionsQ2 2026: 794 institutions
Value heldQ1 2025: $34.8B
Q1 2021: $15.4BQ2 2021: $19.0BQ3 2021: $21.1BQ4 2021: $19.0BQ1 2022: $18.6BQ2 2022: $16.6BQ3 2022: $26.7BQ4 2022: $28.4BQ1 2023: $24.0BQ2 2023: $22.5BQ3 2023: $20.9BQ4 2023: $22.4BQ1 2024: $17.2BQ2 2024: $29.1BQ3 2024: $34.1BQ4 2024: $30.1BQ1 2025: $34.8BQ2 2025: $43.1BQ3 2025: $59.2BQ4 2025: $52.7BQ1 2026: $43.4BQ2 2026: $40.1B
Institutions holding ALNY and their total value by quarter
QuarterHoldersValue
Q2 2026794$40.1B
Q1 2026793$43.4B
Q4 2025852$52.7B
Q3 2025823$59.2B
Q2 2025653$43.1B
Q1 2025625$34.8B
Q4 2024594$30.1B
Q3 2024569$34.1B
Q2 2024525$29.1B
Q1 2024499$17.2B
Q4 2023501$22.4B
Q3 2023454$20.9B
Q2 2023477$22.5B
Q1 2023478$24.0B
Q4 2022489$28.4B
Q3 2022497$26.7B
Q2 2022424$16.6B
Q1 2022443$18.6B
Q4 2021435$19.0B
Q3 2021407$21.1B
Q2 2021401$19.0B
Q1 2021391$15.4B

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q4 2024.

Institutions holding ALNY in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Nissay Asset Management Corp16,214$4.38M0.03%+267+1.7%Added
Silvant Capital Management LLC16,195$4.37M0.20%00.0%Unchanged
Creative Planning16,099$4.35M0.00%+5,286+48.9%Added
Point72 Europe (London) LLP15,958$4.31M0.30%+15,958New
Tredje AP-fonden15,907$4.30M0.04%+6,165+63.3%Added
BNP PARIBAS ASSET MANAGEMENT Holding S.A.15,833$4.29M0.01%+3,784+31.4%Added
Jump Financial, LLC15,717$4.24M0.06%+572+3.8%Added
Jefferies Financial Group Inc.15,347$4.14M0.07%+15,347New
Himension Fund15,302$4.13M0.35%+10,773+237.9%Added
Point72 Asia (Singapore) Pte. Ltd.15,006$4.05M1.06%+15,006New
Mariner, LLC14,883$4.02M0.01%+1,217+8.9%Added
Cerity Partners LLC14,642$3.95M0.01%+1,117+8.3%Added
Jupiter Asset Management Ltd14,610$3.94M0.04%−825−5.3%Reduced
Gotham Asset Management, LLC14,517$3.92M0.03%+3,593+32.9%Added
Wealth Enhancement Advisory Services, LLC14,404$3.89M0.01%+1,838+14.6%Added
Aquatic Capital Management LLC14,348$3.87M0.10%−26,204−64.6%Reduced
Mirae Asset Global ETFs Holdings Ltd.13,953$3.76M0.01%−778−5.3%Reduced
OP Asset Management Ltd13,679$3.69M0.06%+13,679New
Aware Super Pty Ltd as trustee of Aware Super13,665$3.69M0.06%00.0%Unchanged
Mutual of America Capital Management LLC13,644$3.68M0.04%+11,881+673.9%Added
Advisory Services Network, LLC13,516$3.65M0.07%+7,248+115.6%Added
EFG Asset Management (Americas) Corp.13,372$3.61M0.73%−1,574−10.5%Reduced
The PNC Financial Services Group, Inc.13,125$3.54M0.00%+585+4.7%Added
Balyasny Asset Management LLC13,116$3.54M0.01%+13,116New
Diadema Partners LP13,115$3.54M2.83%+13,115New
Sterling Capital Management LLC13,097$3.54M0.05%−4,990−27.6%Reduced
Public Employees Retirement Association of Colorado13,073$3.53M0.02%00.0%Unchanged
Sumitomo Mitsui DS Asset Management Company, Ltd12,957$3.50M0.04%+1,346+11.6%Added
MML Investors Services, LLC12,927$3.49M0.01%+2,189+20.4%Added
Daiwa Securities Group Inc.12,906$3.48M0.01%+355+2.8%Added
E Fund Management Co., Ltd.12,708$3.43M0.16%+413+3.4%Added
Portman Square Capital LLP12,529$3.38M0.47%−410−3.2%Reduced
Guggenheim Capital LLC12,367$3.34M0.03%−416−3.3%Reduced
Voleon Capital Management LP11,914$3.22M0.25%−25,267−68.0%Reduced
Lazard Asset Management LLC11,888$3.21M0.00%−12,306−50.9%Reduced
Mirabella Financial Services LLP11,737$3.18M0.13%+1,198+11.4%Added
Blair William & Co11,078$2.99M0.01%−884−7.4%Reduced
Elo Mutual Pension Insurance Co10,905$2.94M0.07%−2,303−17.4%Reduced
Verition Fund Management LLC10,779$2.91M0.02%+7,876+271.3%Added
Cullen/Frost Bankers, Inc.10,717$2.89M0.04%+78+0.7%Added
Bank of Montreal10,684$2.88M0.00%−923−8.0%Reduced
Assetmark, Inc10,641$2.87M0.01%+608+6.1%Added
Boothbay Fund Management, LLC10,090$2.72M0.10%+10,090New
S&CO Inc10,050$2.71M0.18%+4,300+74.8%Added
Nordea Investment Management AB10,235$2.71M0.00%+47+0.5%Added
Traynor Capital Management, Inc.9,833$2.66M0.22%+483+5.2%Added
Silvercrest Asset Management Group LLC9,821$2.65M0.02%+4,930+100.8%Added
Swiss Life Asset Management Ltd9,810$2.65M0.02%−3,004−23.4%Reduced
Mackenzie Financial Corp9,485$2.56M0.00%+626+7.1%Added
Federation des caisses Desjardins du Quebec9,422$2.55M0.01%+341+3.8%Added
Suvretta Capital Management, LLC9,370$2.53M0.10%+9,370New
TB Alternative Assets Ltd.9,168$2.48M0.58%+9,168New
JustInvest LLC9,088$2.45M0.04%+514+6.0%Added
LMR Partners LLP9,000$2.43M0.05%−2,901−24.4%Reduced
Acadian Asset Management LLC8,977$2.42M0.01%−7,699−46.2%Reduced
Amalgamated Bank8,853$2.39M0.02%+369+4.3%Added
Profund Advisors LLC8,826$2.38M0.10%−869−9.0%Reduced
Kentucky Retirement Systems8,794$2.37M0.07%+8,794New
ASR Vermogensbeheer N.V.8,763$2.37M0.04%+8,763New
Wealthfront Advisers LLC8,721$2.35M0.01%−3,899−30.9%Reduced
FORA Capital, LLC8,624$2.33M0.24%−4,074−32.1%Reduced
Commonwealth Equity Services, LLC8,471$2.29M0.00%+1,934+29.6%Added
Hussman Strategic Advisors, Inc.8,400$2.27M0.55%+8,400New
Nisa Investment Advisors, LLC8,155$2.20M0.01%−5,162−38.8%Reduced
Values First Advisors, Inc.8,113$2.19M1.28%−879−9.8%Reduced
Cetera Investment Advisers8,017$2.16M0.00%+3,247+68.1%Added
SIH Partners, LLLP7,959$2.15M0.19%+7,959New
M&T Bank Corp7,868$2.12M0.01%−740−8.6%Reduced
Clearbridge Investments, LLC7,777$2.10M0.00%+7,777New
Gulf International Bank (UK) Ltd7,364$1.99M0.07%−2,390−24.5%Reduced
MetLife Investment Management7,295$1.97M0.01%−9−0.1%Reduced
Twin Tree Management, LP7,074$1.91M0.04%+7,074New
Stifel Financial Corp7,073$1.91M0.00%−2,944−29.4%Reduced
Man Group plc7,071$1.91M0.01%−9,311−56.8%Reduced
Simplex Trading, LLC6,704$1.81M0.06%+1,875+38.8%Added
Pallas Capital Advisors LLC6,635$1.79M0.07%+3,227+94.7%Added
AG2R la Mondiale Gestion D'Actifs5,825$1.77M0.10%+5,825New
Gateway Investment Advisers LLC6,540$1.77M0.02%−843−11.4%Reduced
Mirae Asset Global Investments Co., Ltd.6,534$1.76M0.01%−2,596−28.4%Reduced
NEOS Investment Management LLC6,475$1.75M0.03%−9,848−60.3%Reduced
Tema ETFs LLC6,475$1.75M0.52%−9,848−60.3%Reduced
Quantinno Capital Management LP6,432$1.74M0.01%+1,876+41.2%Added
Assenagon Asset Management S.A.6,405$1.73M0.00%−13,513−67.8%Reduced
Captrust Financial Advisors6,381$1.72M0.00%−33−0.5%Reduced
SummitTX Capital, L.P.6,326$1.71M0.08%+6,326New
Pathstone Holdings, LLC6,298$1.70M0.01%+115+1.9%Added
Squarepoint Ops LLC6,268$1.69M0.00%−121,429−95.1%Reduced
Jain Global LLC6,221$1.68M0.03%+6,221New
Burney Co6,202$1.67M0.06%−19,536−75.9%Reduced
Group One Trading, L.P.6,202$1.67M0.07%+6,202New
Genus Capital Management Inc.6,130$1.66M0.24%+6,130New
Toroso Investments, LLC6,127$1.65M0.01%−7,061−53.5%Reduced
Motley Fool Asset Management LLC6,029$1.63M0.09%+4,130+217.5%Added
Maryland State Retirement & Pension System6,021$1.63M0.04%−969−13.9%Reduced
Empowered Funds, LLC5,901$1.59M0.02%−1,729−22.7%Reduced
Intech Investment Management LLC5,898$1.59M0.02%−1,675−22.1%Reduced
CIBC World Markets Corp5,868$1.58M0.01%+58+1.0%Added
Advisors Asset Management, Inc.5,851$1.58M0.03%+204+3.6%Added
ProShare Advisors LLC5,840$1.58M0.00%−270−4.4%Reduced
E. Ohman J:or Asset Management AB5,800$1.57M0.04%−300−4.9%Reduced