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Alnylam Pharmaceuticals, Inc.

ALNY
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001178670

No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.

13F holders, Q4 2022

Institutional positions in Alnylam Pharmaceuticals, Inc. as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
489
+1 vs. Q3 2022
Shares held
119.5M
−13.5M (−10.2%) vs. Q3 2022
Total value
$28.4B
+$1.76B (+6.6%) vs. Q3 2022
New holders
85
178 more added
Sold out
84
149 more reduced

9 institutions that held it in Q3 2022 haven't filed for Q4 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2022: 489 institutions
Q1 2021: 391 institutionsQ2 2021: 401 institutionsQ3 2021: 407 institutionsQ4 2021: 435 institutionsQ1 2022: 443 institutionsQ2 2022: 424 institutionsQ3 2022: 497 institutionsQ4 2022: 489 institutionsQ1 2023: 478 institutionsQ2 2023: 477 institutionsQ3 2023: 454 institutionsQ4 2023: 501 institutionsQ1 2024: 499 institutionsQ2 2024: 525 institutionsQ3 2024: 569 institutionsQ4 2024: 594 institutionsQ1 2025: 625 institutionsQ2 2025: 653 institutionsQ3 2025: 823 institutionsQ4 2025: 852 institutionsQ1 2026: 793 institutionsQ2 2026: 794 institutions
Value heldQ4 2022: $28.4B
Q1 2021: $15.4BQ2 2021: $19.0BQ3 2021: $21.1BQ4 2021: $19.0BQ1 2022: $18.6BQ2 2022: $16.6BQ3 2022: $26.7BQ4 2022: $28.4BQ1 2023: $24.0BQ2 2023: $22.5BQ3 2023: $20.9BQ4 2023: $22.4BQ1 2024: $17.2BQ2 2024: $29.1BQ3 2024: $34.1BQ4 2024: $30.1BQ1 2025: $34.8BQ2 2025: $43.1BQ3 2025: $59.2BQ4 2025: $52.7BQ1 2026: $43.4BQ2 2026: $40.1B
Institutions holding ALNY and their total value by quarter
QuarterHoldersValue
Q2 2026794$40.1B
Q1 2026793$43.4B
Q4 2025852$52.7B
Q3 2025823$59.2B
Q2 2025653$43.1B
Q1 2025625$34.8B
Q4 2024594$30.1B
Q3 2024569$34.1B
Q2 2024525$29.1B
Q1 2024499$17.2B
Q4 2023501$22.4B
Q3 2023454$20.9B
Q2 2023477$22.5B
Q1 2023478$24.0B
Q4 2022489$28.4B
Q3 2022497$26.7B
Q2 2022424$16.6B
Q1 2022443$18.6B
Q4 2021435$19.0B
Q3 2021407$21.1B
Q2 2021401$19.0B
Q1 2021391$15.4B

Institutions, Q4 2022

Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q3 2022.

Institutions holding ALNY in Q4 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Raymond James & Associates11,117$2.64M0.00%+500+4.7%Added
ETF Managers Group, LLC11,124$2.64M0.12%−90−0.8%Reduced
Gateway Investment Advisers LLC11,201$2.66M0.03%+260+2.4%Added
Westpac Banking Corp11,262$2.68M0.04%+861+8.3%Added
Comerica Bank11,761$2.75M0.02%+34+0.3%Added
Bamco Inc11,650$2.77M0.01%+1,250+12.0%Added
Weiss Multi-Strategy Advisers LLC11,695$2.78M0.08%+3,734+46.9%Added
ProShare Advisors LLC12,041$2.86M0.01%+33+0.3%Added
Zeke Capital Advisors, LLC12,770$3.03M0.20%−1,524−10.7%Reduced
Standard Life Aberdeen plc13,124$3.12M0.01%+915+7.5%Added
Teacher Retirement System of Texas13,365$3.18M0.02%−4,009−23.1%Reduced
Cubist Systematic Strategies, LLC13,472$3.20M0.03%−89,342−86.9%Reduced
China Universal Asset Management Co., Ltd.13,604$3.23M1.30%+12,480+1,110.3%Added
Silvant Capital Management LLC13,661$3.25M0.23%+3,522+34.7%Added
Profund Advisors LLC13,724$3.26M0.21%+636+4.9%Added
LPL Financial LLC13,785$3.28M0.00%+547+4.1%Added
Amalgamated Bank13,867$3.29M0.03%+387+2.9%Added
Envestnet Asset Management Inc14,086$3.35M0.00%−3,000−17.6%Reduced
Nissay Asset Management Corp14,710$3.50M0.03%−48−0.3%Reduced
CWM Advisors, LLC14,824$3.52M0.45%+1,352+10.0%Added
Caisse de Depot Et Placement du Quebec14,900$3.54M0.01%+14,900New
Sabadell Asset Management, S.A S.G.I.I.C16,205$3.65M0.76%−22,977−58.6%Reduced
EFG Asset Management (Americas) Corp.15,417$3.66M0.91%+275+1.8%Added
The PNC Financial Services Group, Inc.15,583$3.70M0.00%−214−1.4%Reduced
Karani Asset Management LLC15,628$3.71M4.33%−4,538−22.5%Reduced
Public Employees Retirement Association of Colorado15,690$3.73M0.02%00.0%Unchanged
Artia Global Partners LP15,971$3.80M1.46%+15,971New
Xponance, Inc.16,677$3.96M0.06%+2,352+16.4%Added
Allianz Asset Management GmbH18,353$4.36M0.01%−3,390−15.6%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)18,914$4.49M0.02%−27,346−59.1%Reduced
Gulf International Bank (UK) Ltd19,986$4.75M0.08%+75+0.4%Added
Oregon Public Employees Retirement Fund20,020$4.76M0.06%+20,020New
Guggenheim Capital LLC20,817$4.95M0.04%+1,560+8.1%Added
Utah Retirement Systems21,771$5.17M0.08%+199+0.9%Added
Capital Group Investment Management Pte. Ltd.22,050$5.24M0.20%+22,050New
DnB Asset Management AS22,197$5.28M0.04%+1,214+5.8%Added
Sectoral Asset Management Inc22,810$5.42M1.05%+130+0.6%Added
IFM Investors Pty Ltd23,421$5.57M0.09%+3,357+16.7%Added
Principal Financial Group Inc23,963$5.69M0.00%−2,482−9.4%Reduced
Bank of Montreal24,068$5.73M0.00%−34,081−58.6%Reduced
Tredje AP-fonden24,264$5.77M0.10%+422+1.8%Added
Mackenzie Financial Corp25,217$5.99M0.01%+1,703+7.2%Added
Mariner, LLC25,664$6.10M0.02%−780−2.9%Reduced
Intech Investment Management LLC26,072$6.20M0.05%+10,149+63.7%Added
SEI Investments Co27,632$6.57M0.01%−737−2.6%Reduced
BNP Paribas Arbitrage, SA28,111$6.68M0.02%−61,239−68.5%Reduced
Erste Asset Management GmbH28,510$6.79M0.14%−2,420−7.8%Reduced
Forsta Ap-Fonden28,600$6.80M0.08%+5,500+23.8%Added
EFG Asset Management (North America) Corp.28,584$6.80M1.53%−170−0.6%Reduced
Fjarde Ap-Fonden /Fourth Swedish National Pension Fund28,915$6.87M0.10%−1,800−5.9%Reduced
Susquehanna International Group, LLP30,665$7.29M0.01%−11,752−27.7%Reduced
USS Investment Management Ltd31,234$7.42M0.11%−45,569−59.3%Reduced
Brown Advisory Inc31,815$7.56M0.01%−1,327−4.0%Reduced
Wealthfront Advisers LLC32,586$7.74M0.04%+14,210+77.3%Added
HSBC Holdings PLC32,734$7.78M0.01%−2,659−7.5%Reduced
Federation des caisses Desjardins du Quebec33,699$8.01M0.09%00.0%Unchanged
Nekton Capital Ltd.33,890$8.05M1.82%00.0%Unchanged
Arizona State Retirement System33,974$8.07M0.08%+803+2.4%Added
Integral Health Asset Management, LLC35,000$8.32M1.88%−35,000−50.0%Reduced
DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main35,375$8.41M0.01%00.0%Unchanged
Russell Investments Group, Ltd.36,099$8.59M0.02%−2,003−5.3%Reduced
Korea Investment CORP36,143$8.59M0.03%−20,987−36.7%Reduced
Rafferty Asset Management, LLC36,303$8.63M0.07%+3,411+10.4%Added
Toronto Dominion Bank36,670$8.71M0.01%+9,911+37.0%Added
Ensign Peak Advisors, Inc37,093$8.82M0.02%+1,563+4.4%Added
Allspring Global Investments Holdings, LLC37,268$8.86M0.02%−246−0.7%Reduced
Silverarc Capital Management, LLC37,652$8.95M3.08%+5,107+15.7%Added
International Biotechnology Trust PLC38,000$9.02M2.79%00.0%Unchanged
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.40,469$9.45M0.03%+3,269+8.8%Added
Rosenblum Silverman Sutton S F Inc39,883$9.48M3.45%−246−0.6%Reduced
Royal London Asset Management Ltd42,078$9.99M0.04%+1,436+3.5%Added
Storebrand Asset Management AS42,452$10.1M0.06%+1,253+3.0%Added
Great West Life Assurance Co42,309$10.1M0.03%−308−0.7%Reduced
Trexquant Investment LP43,673$10.4M0.29%+561+1.3%Added
Macquarie Group Ltd45,218$10.7M0.01%+934+2.1%Added
Federated Hermes, Inc.47,109$11.2M0.03%+47,109New
Capital International Inc47,210$11.2M0.24%+8,148+20.9%Added
UBS Group AG47,351$11.3M0.01%+1,655+3.6%Added
Ameriprise Financial Inc47,375$11.3M0.00%+37,804+395.0%Added
Asset Management One Co.,Ltd.47,832$11.4M0.06%−1,025−2.1%Reduced
Robeco Institutional Asset Management B.V.51,987$12.4M0.04%+12,628+32.1%Added
Nicholas Investment Partners, LP52,884$12.6M1.10%+4,582+9.5%Added
Andra AP-fonden55,600$13.2M0.40%+7,000+14.4%Added
Sofinnova Investments, Inc.56,448$13.4M0.82%+56,448New
Clearbridge Investments, LLC56,660$13.5M0.01%+56,660New
Lombard Odier Asset Management (Switzerland) SA56,738$13.5M1.08%+21,125+59.3%Added
Nomura Asset Management Co Ltd57,500$13.7M0.08%−1,308−2.2%Reduced
Mirae Asset Global Investments Co., Ltd.58,330$13.9M0.04%−14,361−19.8%Reduced
Victory Capital Management Inc60,132$14.3M0.02%+1,045+1.8%Added
Neuberger Berman Group LLC60,770$14.4M0.01%+55,952+1,161.3%Added
Teachers Retirement System of the State of Kentucky61,053$14.5M0.15%+1,596+2.7%Added
Canada Pension Plan Investment Board62,123$14.8M0.03%−9,060−12.7%Reduced
Capital International Sarl66,876$15.9M1.12%+22,551+50.9%Added
Public Employees Retirement System of Ohio68,099$16.2M0.07%+6,707+10.9%Added
Driehaus Capital Management LLC69,251$16.5M0.25%+1,169+1.7%Added
Alliancebernstein L.P.71,184$16.9M0.01%−3,784−5.0%Reduced
State of New Jersey Common Pension Fund D72,232$17.2M0.06%00.0%Unchanged
Rhenman & Partners Asset Management AB73,000$17.3M1.81%−2,000−2.7%Reduced
State of Wisconsin Investment Board85,434$20.3M0.07%−4,935−5.5%Reduced
Treasurer of the State of North Carolina86,367$20.5M0.12%+1,880+2.2%Added