Ionis Pharmaceuticals Inc
IONS- 交易所
- Nasdaq
- 產業
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
近 90 天，Ionis Pharmaceuticals Inc 內部人申報 1 筆公開市場買進、4 筆賣出；2026 年第 2 季末有 515 家機構在 13F 申報持有，市值合計 $142.6 億；大師中只有方舟投資持有。
2025 年第 3 季 13F 持有人
Ionis Pharmaceuticals Inc 在 2025/9/30 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 437
- 較 2025 年第 2 季 +78 家
- 持有股數
- 1.68 億
- 較 2025 年第 2 季 −22.1 萬 (−0.1%)
- 總市值
- $110.1 億
- 較 2025 年第 2 季 +$43.6 億 (+65.5%)
- 新進機構
- 115
- 另有 136 家加碼
- 清倉機構
- 37
- 另有 116 家減碼
另有 4 家機構在 2025 年第 2 季持有、還沒有申報 2025 年第 3 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 IONS 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 515 | $142.6 億 |
| 2026 年第 1 季 | 497 | $129.7 億 |
| 2025 年第 4 季 | 494 | $134.6 億 |
| 2025 年第 3 季 | 437 | $110.1 億 |
| 2025 年第 2 季 | 363 | $66.7 億 |
| 2025 年第 1 季 | 344 | $50.3 億 |
| 2024 年第 4 季 | 356 | $56.1 億 |
| 2024 年第 3 季 | 354 | $63.1 億 |
| 2024 年第 2 季 | 357 | $68.3 億 |
| 2024 年第 1 季 | 361 | $61.7 億 |
| 2023 年第 4 季 | 365 | $72.1 億 |
| 2023 年第 3 季 | 312 | $63.5 億 |
| 2023 年第 2 季 | 305 | $56.0 億 |
| 2023 年第 1 季 | 315 | $46.9 億 |
| 2022 年第 4 季 | 339 | $49.3 億 |
| 2022 年第 3 季 | 350 | $55.9 億 |
| 2022 年第 2 季 | 351 | $46.1 億 |
| 2022 年第 1 季 | 333 | $46.3 億 |
| 2021 年第 4 季 | 341 | $37.5 億 |
| 2021 年第 3 季 | 326 | $40.8 億 |
| 2021 年第 2 季 | 338 | $49.6 億 |
| 2021 年第 1 季 | 365 | $55.5 億 |
2025 年第 3 季持有機構
每家機構持有 Ionis Pharmaceuticals Inc 的股數、市值與佔組合比重；股數變化跟 2025 年第 2 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| Treasurer of the State of North Carolina | 69,862 | $457.0 萬 | 0.01% | −2,725−3.8% | 減碼 |
| Erste Asset Management GmbH | 71,800 | $460.6 萬 | 0.04% | +20,500+40.0% | 加碼 |
| Hillsdale Investment Management Inc. | 70,900 | $463.8 萬 | 0.14% | +70,900 | 新進 |
| First Trust Advisors LP | 75,224 | $492.1 萬 | 0.00% | +18,705+33.1% | 加碼 |
| Russell Investments Group, Ltd. | 77,293 | $505.7 萬 | 0.01% | +68,028+734.2% | 加碼 |
| Great Point Partners LLC | 80,000 | $523.4 萬 | 2.19% | −420,000−84.0% | 減碼 |
| Nicola Wealth Management Ltd. | 87,000 | $569.1 萬 | 0.51% | 00.0% | 不變 |
| Standard Life Aberdeen plc | 87,924 | $575.2 萬 | 0.01% | −318,770−78.4% | 減碼 |
| Deutsche Bank AG | 88,803 | $580.9 萬 | 0.00% | +3,525+4.1% | 加碼 |
| DekaBank Deutsche Girozentrale | 93,807 | $598.7 萬 | 0.01% | 00.0% | 不變 |
| Lisanti Capital Growth, LLC | 92,124 | $602.7 萬 | 1.47% | +92,124 | 新進 |
| Susquehanna Portfolio Strategies, LLC | 95,960 | $627.8 萬 | 0.10% | +3,060+3.3% | 加碼 |
| J. Goldman & Co LP | 96,198 | $629.3 萬 | 0.24% | −51,484−34.9% | 減碼 |
| State of Wisconsin Investment Board | 96,837 | $633.5 萬 | 0.01% | +143+0.1% | 加碼 |
| Manufacturers Life Insurance Company, The | 98,023 | $641.3 萬 | 0.01% | +14,637+17.6% | 加碼 |
| Simplex Trading, LLC | 100,206 | $655.5 萬 | 0.14% | +60,568+152.8% | 加碼 |
| Amundi | 101,531 | $700.8 萬 | 0.00% | +101,531 | 新進 |
| DCF Advisers, LLC | 108,413 | $709.2 萬 | 2.69% | +16,663+18.2% | 加碼 |
| Acadian Asset Management LLC | 110,444 | $721.4 萬 | 0.01% | +110,444 | 新進 |
| Voya Investment Management LLC | 111,589 | $730.0 萬 | 0.01% | +47,072+73.0% | 加碼 |
| Van Eck Associates Corp | 111,819 | $731.6 萬 | 0.01% | +38,202+51.9% | 加碼 |
| Nikko Asset Management Americas, Inc. | 114,592 | $749.4 萬 | 0.07% | −25,147−18.0% | 減碼 |
| Neuberger Berman Group LLC | 114,743 | $750.6 萬 | 0.01% | +120+0.1% | 加碼 |
| Sumitomo Mitsui Trust Holdings, Inc. | 114,772 | $750.8 萬 | 0.00% | −24,967−17.9% | 減碼 |
| Healthcare of Ontario Pension Plan Trust Fund | 116,000 | $758.9 萬 | 0.01% | 00.0% | 不變 |
| BLB&B Advisors, LLC | 118,600 | $775.9 萬 | 0.33% | −32,950−21.7% | 減碼 |
| SEI Investments Co | 119,028 | $778.7 萬 | 0.01% | +20,680+21.0% | 加碼 |
| Kennedy Capital Management, Inc. | 122,766 | $803.1 萬 | 0.18% | −9,279−7.0% | 減碼 |
| Rafferty Asset Management, LLC | 125,773 | $822.8 萬 | 0.03% | −18,997−13.1% | 減碼 |
| Exome Asset Management LLC | 131,016 | $857.1 萬 | 5.66% | +9,900+8.2% | 加碼 |
| ADAR1 Capital Management, LLC | 133,818 | $875.4 萬 | 0.87% | −14,643−9.9% | 減碼 |
| Lombard Odier Asset Management (Europe) Ltd | – | $895.8 萬 | 0.46% | – | 新進 |
| State Board of Administration of Florida Retirement System | 143,534 | $939.0 萬 | 0.02% | −10,361−6.7% | 減碼 |
| California State Teachers Retirement System | 145,112 | $949.3 萬 | 0.01% | +80.0% | 加碼 |
| Natixis | 145,286 | $950.5 萬 | 0.05% | +145,286 | 新進 |
| ExodusPoint Capital Management, LP | 152,125 | $995.2 萬 | 0.14% | +152,125 | 新進 |
| Skandinaviska Enskilda Banken AB (publ) | 155,790 | $1,019 萬 | 0.04% | +96,164+161.3% | 加碼 |
| Citigroup Inc | 155,853 | $1,020 萬 | 0.01% | −185,124−54.3% | 減碼 |
| Edmond de Rothschild Holding S.A. | 156,690 | $1,025 萬 | 0.16% | −40,910−20.7% | 減碼 |
| Aquatic Capital Management LLC | 159,045 | $1,040 萬 | 0.19% | +959+0.6% | 加碼 |
| Capricorn Fund Managers Ltd | 162,800 | $1,065 萬 | 3.58% | +162,800 | 新進 |
| Boothbay Fund Management, LLC | 163,462 | $1,069 萬 | 0.28% | +163,462 | 新進 |
| Sicart Associates LLC | 164,318 | $1,075 萬 | 2.91% | −20,978−11.3% | 減碼 |
| New York State Common Retirement Fund | 168,222 | $1,101 萬 | 0.01% | +81,250+93.4% | 加碼 |
| Sonora Investment Management Group, LLC | 169,808 | $1,111 萬 | 0.79% | +6,636+4.1% | 加碼 |
| Sovran Advisors, LLC | 150,856 | $1,119 萬 | 0.99% | −171,057−53.1% | 減碼 |
| Cinctive Capital Management LP | 173,819 | $1,137 萬 | 0.57% | +173,819 | 新進 |
| Rhumbline Advisers | 182,061 | $1,191 萬 | 0.01% | +462+0.3% | 加碼 |
| Great Lakes Advisors, LLC | 186,950 | $1,223 萬 | 0.10% | −212,696−53.2% | 減碼 |
| Tocqueville Asset Management L.P. | 193,045 | $1,263 萬 | 0.18% | +5,700+3.0% | 加碼 |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 197,434 | $1,292 萬 | 0.02% | +47,595+31.8% | 加碼 |
| Schonfeld Strategic Advisors LLC | 200,839 | $1,314 萬 | 0.09% | −248,367−55.3% | 減碼 |
| Stifel Financial Corp | 202,628 | $1,326 萬 | 0.01% | +6,271+3.2% | 加碼 |
| Trexquant Investment LP | 215,121 | $1,407 萬 | 0.15% | +86,252+66.9% | 加碼 |
| California Public Employees Retirement System | 215,845 | $1,412 萬 | 0.01% | +13,852+6.9% | 加碼 |
| Orion Investment Co | 224,705 | $1,470 萬 | 4.70% | +7,335+3.4% | 加碼 |
| Jain Global LLC | 225,739 | $1,477 萬 | 0.19% | +218,544+3,037.4% | 加碼 |
| Raymond James Financial Inc | 240,424 | $1,573 萬 | 0.01% | +29,832+14.2% | 加碼 |
| Privium Fund Management B.V. | 248,894 | $1,628 萬 | 2.93% | −18,700−7.0% | 減碼 |
| Algert Global LLC | 252,281 | $1,650 萬 | 0.28% | +214,191+562.3% | 加碼 |
| GW&K Investment Management, LLC | 264,007 | $1,727 萬 | 0.15% | −184,823−41.2% | 減碼 |
| Sector Gamma AS | 270,963 | $1,773 萬 | 4.40% | −14,879−5.2% | 減碼 |
| Wells Fargo & Company | 285,293 | $1,866 萬 | 0.00% | +75,436+35.9% | 加碼 |
| Swiss National Bank | 293,100 | $1,917 萬 | 0.01% | +4,500+1.6% | 加碼 |
| Rhenman & Partners Asset Management AB | 310,000 | $2,028 萬 | 2.24% | +128,000+70.3% | 加碼 |
| Alyeska Investment Group, L.P. | 311,258 | $2,036 萬 | 0.06% | +152,250+95.7% | 加碼 |
| Assenagon Asset Management S.A. | 312,297 | $2,043 萬 | 0.03% | +294,643+1,669.0% | 加碼 |
| Legal & General Group Plc | 319,565 | $2,091 萬 | 0.00% | −84,801−21.0% | 減碼 |
| Man Group plc | 333,820 | $2,184 萬 | 0.04% | +324,851+3,621.9% | 加碼 |
| Jane Street Group, LLC | 365,070 | $2,388 萬 | 0.03% | +365,070 | 新進 |
| BNP Paribas Arbitrage, SA | 383,226 | $2,507 萬 | 0.02% | +205,464+115.6% | 加碼 |
| Squarepoint Ops LLC | 383,792 | $2,511 萬 | 0.05% | +249,397+185.6% | 加碼 |
| AXA Investment Managers S.A. | 406,451 | $2,659 萬 | 0.07% | +406,451 | 新進 |
| Ikarian Capital, LLC | 415,163 | $2,716 萬 | 6.15% | +415,163 | 新進 |
| Nuveen, LLC | 415,618 | $2,719 萬 | 0.01% | +170,533+69.6% | 加碼 |
| Boone Capital Management LLC | 417,833 | $2,733 萬 | 8.96% | +417,833 | 新進 |
| Susquehanna International Group, LLP | 420,950 | $2,754 萬 | 0.04% | +420,950 | 新進 |
| C WorldWide Group Holding A/S | 426,000 | $2,787 萬 | 0.43% | −24,000−5.3% | 減碼 |
| Teacher Retirement System of Texas | 473,945 | $3,101 萬 | 0.12% | −194,328−29.1% | 減碼 |
| Pinnacle Associates Ltd | 481,751 | $3,152 萬 | 0.42% | −12,788−2.6% | 減碼 |
| Renaissance Technologies LLC | 486,714 | $3,184 萬 | 0.04% | +216,000+79.8% | 加碼 |
| Hudson Bay Capital Management LP | 515,000 | $3,369 萬 | 0.20% | −235,000−31.3% | 減碼 |
| Invesco Ltd. | 519,070 | $3,396 萬 | 0.01% | +262,835+102.6% | 加碼 |
| Bank of New York Mellon Corp | 532,114 | $3,481 萬 | 0.01% | +4,926+0.9% | 加碼 |
| Eversept Partners, LP | 538,661 | $3,524 萬 | 2.70% | −50,239−8.5% | 減碼 |
| JPMorgan Chase & Co | 544,468 | $3,562 萬 | 0.00% | +149,490+37.8% | 加碼 |
| Tang Capital Management LLC | 550,000 | $3,598 萬 | 1.39% | +400,000+266.7% | 加碼 |
| Baker Bros. Advisors LP | 566,798 | $3,708 萬 | 0.27% | +566,798 | 新進 |
| Groupama Asset Managment | 561,777 | $3,744 萬 | 0.55% | −99,180−15.0% | 減碼 |
| Candriam Luxembourg S.C.A. | 611,237 | $3,999 萬 | 0.21% | −113,503−15.7% | 減碼 |
| Arrowstreet Capital, Limited Partnership | 630,136 | $4,122 萬 | 0.03% | +630,136 | 新進 |
| D. E. Shaw & Co., Inc. | 630,938 | $4,128 萬 | 0.03% | +630,938 | 新進 |
| ARK Investment Management LLC大師方舟投資 | 631,215 | $4,129 萬 | 0.25% | −269,103−29.9% | 減碼 |
| Barclays PLC | 714,048 | $4,671 萬 | 0.02% | +130,782+22.4% | 加碼 |
| Nomura Holdings Inc | 733,398 | $4,798 萬 | 0.22% | +701,237+2,180.4% | 加碼 |
| Bank of Montreal | 747,402 | $4,890 萬 | 0.02% | +264,113+54.6% | 加碼 |
| Summit Partners Public Asset Management, LLC | 750,000 | $4,907 萬 | 1.60% | +750,000 | 新進 |
| Balyasny Asset Management LLC | 760,111 | $4,973 萬 | 0.10% | −8,537−1.1% | 減碼 |
| Ameriprise Financial Inc | 765,822 | $5,010 萬 | 0.01% | +397,703+108.0% | 加碼 |
| Goldman Sachs Group Inc | 777,570 | $5,087 萬 | 0.01% | −3700.0% | 減碼 |