Xeris Biopharma Holdings, Inc.
XERS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001867096
In the last 90 days, Xeris Biopharma Holdings, Inc. insiders filed 0 open-market purchases and 8 sales; 242 institutions reported holding it in 13F filings for Q2 2026, worth $857.1M in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Xeris Biopharma Holdings, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 227
- −3 vs. Q3 2025
- Shares held
- 100.9M
- +3.95M (+4.1%) vs. Q3 2025
- Total value
- $792.0M
- +$2.83M (+0.4%) vs. Q3 2025
- New holders
- 35
- 79 more added
- Sold out
- 38
- 78 more reduced
1 institution that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting XERS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 242 | $857.1M |
| Q1 2026 | 239 | $610.3M |
| Q4 2025 | 227 | $792.0M |
| Q3 2025 | 231 | $789.3M |
| Q2 2025 | 201 | $422.9M |
| Q1 2025 | 199 | $480.9M |
| Q4 2024 | 162 | $222.2M |
| Q3 2024 | 144 | $182.2M |
| Q2 2024 | 135 | $136.6M |
| Q1 2024 | 142 | $133.7M |
| Q4 2023 | 120 | $140.8M |
| Q3 2023 | 111 | $102.3M |
| Q2 2023 | 105 | $146.7M |
| Q1 2023 | 92 | $80.6M |
| Q4 2022 | 97 | $71.6M |
| Q3 2022 | 101 | $89.3M |
| Q2 2022 | 103 | $91.3M |
| Q1 2022 | 103 | $129.2M |
| Q4 2021 | 92 | $120.2M |
| Q3 2021 | 71 | $42.9M |
| Q2 2021 | 94 | $114.9M |
| Q1 2021 | 103 | $149.7M |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Xeris Biopharma Holdings, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Police & Firemen's Retirement System of New Jersey | 40,738 | $319.8K | 0.00% | −624−1.5% | Reduced |
| LJI Wealth Management, LLC | 42,350 | $332.4K | 0.05% | 00.0% | Unchanged |
| State of Wyoming | 42,458 | $333.3K | 0.04% | +29,558+229.1% | Added |
| AlphaCentric Advisors LLC | 43,392 | $340.6K | 0.34% | +43,392 | New |
| New York State Common Retirement Fund | 43,422 | $340.9K | 0.00% | 00.0% | Unchanged |
| Arizona State Retirement System | 45,269 | $355.4K | 0.00% | −2,093−4.4% | Reduced |
| Persistent Asset Partners Ltd | 45,609 | $358.0K | 0.17% | +28,407+165.1% | Added |
| Manufacturers Life Insurance Company, The | 45,801 | $359.5K | 0.00% | −4,343−8.7% | Reduced |
| Axq Capital, LP | 46,454 | $364.7K | 0.08% | +20,098+76.3% | Added |
| Campbell & CO Investment Adviser LLC | 47,454 | $372.5K | 0.02% | −56,162−54.2% | Reduced |
| Man Group plc | 47,775 | $375.0K | 0.00% | +47,775 | New |
| Penn Capital Management Co Inc | 48,064 | $377.3K | 0.03% | +48,064 | New |
| Weiss Asset Management LP | 50,001 | $392.5K | 0.01% | 00.0% | Unchanged |
| Dark Forest Capital Management LP | 52,043 | $408.5K | 0.02% | −84,688−61.9% | Reduced |
| Deerfield Management Company, L.P. (Series C) | 52,230 | $410.0K | 0.01% | −68,670−56.8% | Reduced |
| Advisor Group Holdings, Inc. | 52,285 | $410.4K | 0.00% | +11,934+29.6% | Added |
| CWM, LLC | 55,356 | $435.0K | 0.00% | −83−0.1% | Reduced |
| Winton Group Ltd | 64,597 | $507.1K | 0.02% | −26,196−28.9% | Reduced |
| Intech Investment Management LLC | 65,090 | $511.0K | 0.00% | +9,754+17.6% | Added |
| STRS Ohio | 65,500 | $514.2K | 0.00% | 00.0% | Unchanged |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 65,767 | $516.3K | 0.00% | +33,115+101.4% | Added |
| Integrated Quantitative Investments LLC | 66,170 | $519.4K | 0.11% | +66,170 | New |
| EntryPoint Capital, LLC | 68,083 | $534.5K | 0.21% | +15,068+28.4% | Added |
| Janus Henderson Group PLC | 69,887 | $548.3K | 0.00% | 00.0% | Unchanged |
| Mirae Asset Global ETFs Holdings Ltd. | 71,311 | $559.8K | 0.00% | −200.0% | Reduced |
| Teachers Retirement System of the State of Kentucky | 72,907 | $572.0K | 0.00% | +72,907 | New |
| Western Wealth Management, LLC | 75,675 | $594.0K | 0.03% | +75,675 | New |
| Quantbot Technologies LP | 77,648 | $609.5K | 0.02% | +8,283+11.9% | Added |
| Quarry LP | 80,000 | $628.0K | 0.10% | −2,500−3.0% | Reduced |
| EAM Investors, LLC | 80,154 | $629.2K | 0.07% | −522,947−86.7% | Reduced |
| MetLife Investment Management | 81,594 | $640.5K | 0.00% | −5,724−6.6% | Reduced |
| LPL Financial LLC | 84,861 | $666.2K | 0.00% | +51,559+154.8% | Added |
| Ieq Capital, LLC | 86,520 | $679.2K | 0.00% | −21,433−19.9% | Reduced |
| Jefferies Financial Group Inc. | 87,800 | $689.2K | 0.01% | +87,800 | New |
| Engineers Gate Manager LP | 89,404 | $701.8K | 0.01% | −20,590−18.7% | Reduced |
| Y-Intercept (Hong Kong) Ltd | 90,645 | $711.6K | 0.02% | +8,464+10.3% | Added |
| Brevan Howard Capital Management LP | 92,416 | $725.5K | 0.01% | −39,744−30.1% | Reduced |
| Round Rock Advisors, LLC | 96,816 | $760.0K | 0.11% | +33,044+51.8% | Added |
| Citigroup Inc | 98,746 | $775.2K | 0.00% | +28,491+40.6% | Added |
| Calamos Advisors LLC | 99,117 | $778.1K | 0.00% | −37,980−27.7% | Reduced |
| Resolute Capital Asset Partners LLC | 100,000 | $785.0K | 0.38% | +100,000 | New |
| Thompson Siegel & Walmsley LLC | 100,884 | $792.0K | 0.01% | 00.0% | Unchanged |
| Ambassador Advisors, LLC | 106,730 | $837.8K | 0.12% | +106,730 | New |
| SG Americas Securities, LLC | 110,180 | $865.0K | 0.00% | +26,966+32.4% | Added |
| Invesco Ltd. | 112,130 | $880.2K | 0.00% | −470,978−80.8% | Reduced |
| Creative Planning | 116,538 | $914.8K | 0.00% | −10,442−8.2% | Reduced |
| Susquehanna International Group, LLP | 117,355 | $921.2K | 0.00% | +35,884+44.0% | Added |
| Franklin Resources Inc | 121,428 | $953.2K | 0.00% | +12,286+11.3% | Added |
| Globeflex Capital L P | 123,184 | $967.0K | 0.15% | 00.0% | Unchanged |
| Group One Trading, L.P. | 123,561 | $970.0K | 0.03% | +117,537+1,951.1% | Added |
| Polen Capital Management LLC | 133,416 | $1.05M | 0.00% | +225+0.2% | Added |
| Ameriprise Financial Inc | 143,463 | $1.13M | 0.00% | −10,705−6.9% | Reduced |
| Alliancebernstein L.P. | 144,830 | $1.14M | 0.00% | 00.0% | Unchanged |
| Principal Financial Group Inc | 150,559 | $1.18M | 0.00% | +45,066+42.7% | Added |
| California State Teachers Retirement System | 151,171 | $1.19M | 0.00% | −715−0.5% | Reduced |
| Diadema Partners LP | 170,568 | $1.34M | 0.80% | +95,815+128.2% | Added |
| Wells Fargo & Company | 170,796 | $1.34M | 0.00% | +73,600+75.7% | Added |
| Price T Rowe Associates Inc | 173,463 | $1.36M | 0.00% | +6,675+4.0% | Added |
| Caxton Associates LLP | 174,102 | $1.37M | 0.03% | −107,235−38.1% | Reduced |
| Jane Street Group, LLC | 177,822 | $1.40M | 0.00% | −735,936−80.5% | Reduced |
| Rhumbline Advisers | 189,567 | $1.49M | 0.00% | −24,177−11.3% | Reduced |
| Commonwealth Equity Services, LLC | 197,815 | $1.55M | 0.00% | +720.0% | Added |
| Raymond James Financial Inc | 211,419 | $1.66M | 0.00% | +6,206+3.0% | Added |
| Trexquant Investment LP | 213,581 | $1.68M | 0.01% | −15,839−6.9% | Reduced |
| Arrowstreet Capital, Limited Partnership | 214,786 | $1.69M | 0.00% | +214,786 | New |
| Schonfeld Strategic Advisors LLC | 234,723 | $1.84M | 0.01% | −69,781−22.9% | Reduced |
| Legato Capital Management LLC | 237,431 | $1.86M | 0.16% | +20,626+9.5% | Added |
| Apella Capital, LLC | 245,897 | $1.93M | 0.04% | +235,897+2,359.0% | Added |
| BNP Paribas Arbitrage, SA | 258,368 | $2.03M | 0.00% | −323,351−55.6% | Reduced |
| IHT Wealth Management, LLC | 263,531 | $2.07M | 0.05% | +5,356+2.1% | Added |
| Harvest Investment Services, LLC | 292,677 | $2.30M | 0.43% | −32,878−10.1% | Reduced |
| Swiss National Bank | 318,400 | $2.50M | 0.00% | +8,000+2.6% | Added |
| HRT Financial LP | 332,326 | $2.61M | 0.01% | +259,783+358.1% | Added |
| Jump Financial, LLC | 341,068 | $2.68M | 0.03% | −262,176−43.5% | Reduced |
| State of Wisconsin Investment Board | 357,453 | $2.81M | 0.01% | +6,924+2.0% | Added |
| Barclays PLC | 362,751 | $2.85M | 0.00% | +16,112+4.6% | Added |
| Russell Investments Group, Ltd. | 364,786 | $2.86M | 0.00% | +113,408+45.1% | Added |
| Voss Capital, LLC | 371,709 | $2.92M | 0.16% | +371,709 | New |
| Canada Pension Plan Investment Board | 390,600 | $3.07M | 0.00% | +14,900+4.0% | Added |
| SEI Investments Co | 399,347 | $3.13M | 0.00% | +278,171+229.6% | Added |
| Citadel Advisors LLC | 409,820 | $3.22M | 0.00% | −27,792−6.4% | Reduced |
| Bank of New York Mellon Corp | 434,262 | $3.41M | 0.00% | −5,576−1.3% | Reduced |
| FMR LLC | 439,705 | $3.45M | 0.00% | +79,527+22.1% | Added |
| Castleark Management LLC | 445,950 | $3.50M | 0.10% | +445,950 | New |
| Voya Investment Management LLC | 458,329 | $3.60M | 0.00% | +58,250+14.6% | Added |
| Squarepoint Ops LLC | 482,832 | $3.79M | 0.01% | −196,249−28.9% | Reduced |
| Healthcare of Ontario Pension Plan Trust Fund | 537,483 | $4.22M | 0.01% | +283,483+111.6% | Added |
| UBS Group AG | 601,834 | $4.72M | 0.00% | −1,180,900−66.2% | Reduced |
| Point72 Asset Management, L.P. | 608,080 | $4.77M | 0.01% | +608,080 | New |
| Prudential Financial Inc | 618,949 | $4.86M | 0.01% | −815,255−56.8% | Reduced |
| Renaissance Technologies LLC | 619,660 | $4.86M | 0.01% | −1,003,180−61.8% | Reduced |
| UBS Asset Management Americas Inc | 651,445 | $5.11M | 0.00% | +467,986+255.1% | Added |
| Bank of America Corp | 717,914 | $5.64M | 0.00% | −876,952−55.0% | Reduced |
| Algert Global LLC | 718,844 | $5.64M | 0.09% | +560,884+355.1% | Added |
| Essex Investment Management Co LLC | 734,532 | $5.77M | 0.88% | −15,502−2.1% | Reduced |
| Ishara Investments LP | 800,000 | $6.28M | 7.31% | +800,000 | New |
| Norges Bank | 800,700 | $6.29M | 0.00% | +800,700 | New |
| Voloridge Investment Management, LLC | 811,129 | $6.37M | 0.02% | −223,424−21.6% | Reduced |
| Two Sigma Advisers, LP | 849,334 | $6.67M | 0.01% | −43,908−4.9% | Reduced |
| Federated Hermes, Inc. | 854,888 | $6.71M | 0.01% | +150,505+21.4% | Added |