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Xeris Biopharma Holdings, Inc.

XERS
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001867096

In the last 90 days, Xeris Biopharma Holdings, Inc. insiders filed 0 open-market purchases and 9 sales; 242 institutions reported holding it in 13F filings for Q2 2026, worth $857.1M in total; no superinvestor holds it.

13F holders, Q4 2021

Institutional positions in Xeris Biopharma Holdings, Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
92
+22 vs. Q3 2021
Shares held
41.0M
+23.5M (+134.4%) vs. Q3 2021
Total value
$120.2M
+$77.3M (+180.1%) vs. Q3 2021
New holders
33
33 more added
Sold out
11
15 more reduced

1 institution that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting XERS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 92 institutions
Q1 2021: 103 institutionsQ2 2021: 94 institutionsQ3 2021: 71 institutionsQ4 2021: 92 institutionsQ1 2022: 103 institutionsQ2 2022: 103 institutionsQ3 2022: 101 institutionsQ4 2022: 97 institutionsQ1 2023: 92 institutionsQ2 2023: 105 institutionsQ3 2023: 111 institutionsQ4 2023: 120 institutionsQ1 2024: 142 institutionsQ2 2024: 135 institutionsQ3 2024: 144 institutionsQ4 2024: 162 institutionsQ1 2025: 199 institutionsQ2 2025: 201 institutionsQ3 2025: 231 institutionsQ4 2025: 227 institutionsQ1 2026: 239 institutionsQ2 2026: 242 institutions
Value heldQ4 2021: $120.2M
Q1 2021: $149.7MQ2 2021: $114.9MQ3 2021: $42.9MQ4 2021: $120.2MQ1 2022: $129.2MQ2 2022: $91.3MQ3 2022: $89.3MQ4 2022: $71.6MQ1 2023: $80.6MQ2 2023: $146.7MQ3 2023: $102.3MQ4 2023: $140.8MQ1 2024: $133.7MQ2 2024: $136.6MQ3 2024: $182.2MQ4 2024: $222.2MQ1 2025: $480.9MQ2 2025: $422.9MQ3 2025: $789.3MQ4 2025: $792.0MQ1 2026: $610.3MQ2 2026: $857.1M
Institutions holding XERS and their total value by quarter
QuarterHoldersValue
Q2 2026242$857.1M
Q1 2026239$610.3M
Q4 2025227$792.0M
Q3 2025231$789.3M
Q2 2025201$422.9M
Q1 2025199$480.9M
Q4 2024162$222.2M
Q3 2024144$182.2M
Q2 2024135$136.6M
Q1 2024142$133.7M
Q4 2023120$140.8M
Q3 2023111$102.3M
Q2 2023105$146.7M
Q1 202392$80.6M
Q4 202297$71.6M
Q3 2022101$89.3M
Q2 2022103$91.3M
Q1 2022103$129.2M
Q4 202192$120.2M
Q3 202171$42.9M
Q2 202194$114.9M
Q1 2021103$149.7M

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Xeris Biopharma Holdings, Inc.; share changes are against Q3 2021.

Institutions holding XERS in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Caxton Corp6,310,546$18.5M15.11%+6,310,546New
Stonepine Capital Management, LLC5,656,373$16.6M7.61%+5,656,373New
Vanguard Group Inc5,115,623$15.0M0.00%+2,139,443+71.9%Added
NEA Management Company, LLC3,250,000$9.52M0.19%+3,250,000New
Lazard Asset Management LLC2,480,675$7.27M0.01%+2,330,568+1,552.6%Added
Invesco Ltd.2,036,126$5.97M0.00%−6880.0%Reduced
BlackRock Inc.1,795,513$5.26M0.00%+269,705+17.7%Added
Man Group plc1,658,440$4.86M0.02%+1,622,040+4,456.2%Added
Morgan Stanley1,350,787$3.96M0.00%+1,104,830+449.2%Added
Redmile Group, LLC1,046,587$3.07M0.07%−312,238−23.0%Reduced
Geode Capital Management, LLC1,005,000$2.94M0.00%+300,830+42.7%Added
Tudor Investment Corp Et Al960,111$2.81M0.05%+960,111New
Renaissance Technologies LLC880,194$2.58M0.00%+738,182+519.8%Added
Susquehanna International Group, LLP834,536$2.44M0.00%+225,009+36.9%Added
Granahan Investment Management Inc524,612$1.54M0.03%+59,563+12.8%Added
Deltec Asset Management LLC411,000$1.20M0.20%−49,500−10.7%Reduced
State Street Corp366,509$1.07M0.00%+149,627+69.0%Added
IHT Wealth Management, LLC342,897$1.00M0.07%+8,530+2.6%Added
Simplex Trading, LLC321,395$941.0K0.03%+308,466+2,385.8%Added
Cubist Systematic Strategies, LLC311,797$914.0K0.01%+294,251+1,677.0%Added
Brown Advisory Inc299,754$878.0K0.00%+299,754New
Alpine Global Management, LLC295,000$864.0K0.13%−75,000−20.3%Reduced
Bridgeway Capital Management, LLC242,151$710.0K0.01%−160,149−39.8%Reduced
Goldman Sachs Group Inc227,691$667.0K0.00%+103,507+83.3%Added
Millennium Management LLC221,596$649.0K0.00%−4,643−2.1%Reduced
Commonwealth Equity Services, LLC197,234$577.0K0.00%+99,650+102.1%Added
Northern Trust Corp190,022$557.0K0.00%+67,263+54.8%Added
Susquehanna Fundamental Investments, LLC186,657$547.0K0.01%−87,816−32.0%Reduced
Diversified Trust Co155,650$456.0K0.02%+155,650New
Fairfax Financial Holdings LtdSuperinvestorFairfax Financial151,395$441.0K0.01%+151,395New
683 Capital Management, LLC121,367$356.0K0.02%+91,367+304.6%Added
Qube Research & Technologies Ltd121,627$356.0K0.00%+121,627New
Citadel Advisors LLC114,347$335.0K0.00%+38,513+50.8%Added
Jane Street Group, LLC113,410$332.0K0.00%+97,476+611.7%Added
Gsa Capital Partners LLP111,272$326.0K0.04%+111,272New
Aristides Capital LLC100,080$293.0K0.17%+100,080New
Bank of New York Mellon Corp95,870$281.0K0.00%+40,725+73.9%Added
Cetera Advisor Networks LLC85,375$250.0K0.00%+85,375New
CSS LLC69,834$205.0K0.01%+69,834New
Dimensional Fund Advisors LP69,872$204.0K0.00%+21,402+44.2%Added
Charles Schwab Investment Management Inc67,010$197.0K0.00%+44,532+198.1%Added
Parametric Portfolio Associates LLC65,090$191.0K0.00%+65,090New
Kamunting Street Capital Management, L.P.64,539$189.0K0.17%+64,539New
AE Wealth Management LLC59,666$175.0K0.00%+13,588+29.5%Added
GPS Wealth Strategies Group, LLC59,025$173.0K0.04%+1,000+1.7%Added
Ameriprise Financial Inc50,601$168.0K0.00%+2,401+5.0%Added
Chevy Chase Trust Holdings, Inc.51,243$150.0K0.00%00.0%Unchanged
Ieq Capital, LLC50,169$147.0K0.00%+50,169New
FNY Investment Advisers, LLC49,088$143.0K0.08%+49,088New
Caption Management, LLC47,600$140.0K0.01%+47,600New
Rafferty Asset Management, LLC43,341$127.0K0.00%+14,174+48.6%Added
ExodusPoint Capital Management, LP40,394$118.0K0.00%+40,394New
Evercore Wealth Management, LLC38,801$114.0K0.00%+38,801New
Advisor Group Holdings, Inc.38,773$113.0K0.00%+10,697+38.1%Added
Gladstone Institutional Advisory LLC35,500$104.0K0.01%−18,000−33.6%Reduced
Belvedere Trading LLC47,282$103.0K0.02%+47,282New
Boothbay Fund Management, LLC30,430$89.0K0.00%+30,430New
Bank of America Corp29,708$87.0K0.00%+15,284+106.0%Added
Leonteq Securities AG21,000$61.5K0.00%+21,000New
Royal Bank of Canada20,100$59.0K0.00%−2,400−10.7%Reduced
Searle & Co.20,000$59.0K0.02%00.0%Unchanged
Apollon Wealth Management, LLC20,160$59.0K0.00%00.0%Unchanged
Balyasny Asset Management LLC19,428$57.0K0.00%+19,428New
ProShare Advisors LLC17,561$51.0K0.00%+3,356+23.6%Added
Victory Capital Management Inc15,965$47.0K0.00%+15,965New
HSBC Holdings PLC14,392$42.0K0.00%−827−5.4%Reduced
Squarepoint Ops LLC13,883$41.0K0.00%+1,288+10.2%Added
JPMorgan Chase & Co13,257$39.0K0.00%+8,629+186.5%Added
RTD Financial Advisors, Inc.12,957$38.0K0.00%+12,957New
Price T Rowe Associates Inc12,700$37.0K0.00%−51,700−80.3%Reduced
UBS Group AG12,632$37.0K0.00%−13,900−52.4%Reduced
Avenue 1 Advisors, LLC12,544$37.0K0.02%+12,544New
Whitener Capital Management, Inc.12,000$35.0K0.01%+12,000New
TownSquare Capital, LLC11,506$34.0K0.00%−5,455−32.2%Reduced
Kestra Private Wealth Services, LLC11,550$34.0K0.00%−1,000−8.0%Reduced
Wells Fargo & Company11,679$34.0K0.00%+9,113+355.1%Added
Raymond James & Associates11,300$33.0K0.00%+11,300New
Aigen Investment Management, LP10,586$31.0K0.00%+10,586New
Paloma Partners Management Co10,066$29.0K0.00%+10,066New
Tower Research Capital LLC (TRC)9,400$28.0K0.00%+3,465+58.4%Added
State of Wyoming7,711$23.0K0.01%+7,711New
Parallel Advisors, LLC7,200$21.0K0.00%00.0%Unchanged
TSFG, LLC5,488$16.0K0.01%+5,488New
Citigroup Inc3,721$11.0K0.00%−2,023−35.2%Reduced
Benjamin F. Edwards & Company, Inc.3,000$9.00K0.00%00.0%Unchanged
Sphinx Trading, LP1,404$4.00K0.00%+1,404New
Investment Research & Advisory Group, Inc.803$2.00K0.00%00.0%Unchanged
Allworth Financial LP500$1.00K0.00%00.0%Unchanged
IFP Advisors, Inc200$1.00K0.00%00.0%Unchanged
Northwestern Mutual Wealth Management Co100$00.00%00.0%Unchanged
Daiwa Securities Group Inc.102$00.00%00.0%Unchanged
Lloyd Advisory Services, LLC.71$00.00%00.0%Unchanged
Sessa Capital IM, L.P.0$00.00%−3,661,237−100.0%Sold out
Miracle Mile Advisors, LLC0$00.00%−30,300−100.0%Sold out
Barclays PLC0$00.00%−29,541−100.0%Sold out
GM Advisory Group, Inc.0$00.00%−20,000−100.0%Sold out
Principal Financial Group Inc0$00.00%−11,801−100.0%Sold out
HRT Financial LP0$00.00%−10,435−100.0%Sold out
Captrust Financial Advisors0$00.00%−2,783−100.0%Sold out
Cutler Group LP0$00.00%−1,700−100.0%Sold out