Xeris Biopharma Holdings, Inc.
XERS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001867096
In the last 90 days, Xeris Biopharma Holdings, Inc. insiders filed 0 open-market purchases and 9 sales; 242 institutions reported holding it in 13F filings for Q2 2026, worth $857.1M in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Xeris Biopharma Holdings, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 231
- +32 vs. Q2 2025
- Shares held
- 97.0M
- +6.99M (+7.8%) vs. Q2 2025
- Total value
- $789.3M
- +$369.1M (+87.8%) vs. Q2 2025
- New holders
- 59
- 77 more added
- Sold out
- 27
- 61 more reduced
2 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting XERS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 242 | $857.1M |
| Q1 2026 | 239 | $610.3M |
| Q4 2025 | 227 | $792.0M |
| Q3 2025 | 231 | $789.3M |
| Q2 2025 | 201 | $422.9M |
| Q1 2025 | 199 | $480.9M |
| Q4 2024 | 162 | $222.2M |
| Q3 2024 | 144 | $182.2M |
| Q2 2024 | 135 | $136.6M |
| Q1 2024 | 142 | $133.7M |
| Q4 2023 | 120 | $140.8M |
| Q3 2023 | 111 | $102.3M |
| Q2 2023 | 105 | $146.7M |
| Q1 2023 | 92 | $80.6M |
| Q4 2022 | 97 | $71.6M |
| Q3 2022 | 101 | $89.3M |
| Q2 2022 | 103 | $91.3M |
| Q1 2022 | 103 | $129.2M |
| Q4 2021 | 92 | $120.2M |
| Q3 2021 | 71 | $42.9M |
| Q2 2021 | 94 | $114.9M |
| Q1 2021 | 103 | $149.7M |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Xeris Biopharma Holdings, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| BlackRock, Inc. | 11,927,699 | $97.1M | 0.00% | +391,378+3.4% | Added |
| Vanguard Group Inc | 9,827,917 | $80.0M | 0.00% | +10,980+0.1% | Added |
| D. E. Shaw & Co., Inc. | 5,839,886 | $47.5M | 0.04% | +2,004,479+52.3% | Added |
| Geode Capital Management, LLC | 4,140,174 | $33.7M | 0.00% | +489,486+13.4% | Added |
| State Street Corp | 3,738,329 | $30.4M | 0.00% | −44,871−1.2% | Reduced |
| Qube Research & Technologies Ltd | 3,274,834 | $26.7M | 0.04% | +185,063+6.0% | Added |
| Morgan Stanley | 3,219,701 | $26.2M | 0.00% | −422,883−11.6% | Reduced |
| Nuveen, LLC | 2,827,874 | $23.0M | 0.01% | +227,432+8.7% | Added |
| Driehaus Capital Management LLC | 2,619,129 | $21.3M | 0.15% | +548,054+26.5% | Added |
| Rosalind Advisors, Inc. | 1,795,766 | $14.6M | 5.31% | −359,828−16.7% | Reduced |
| Goldman Sachs Group Inc | 1,795,455 | $14.6M | 0.00% | −476,031−21.0% | Reduced |
| Parkman Healthcare Partners LLC | 1,791,674 | $14.6M | 1.60% | −315,809−15.0% | Reduced |
| UBS Group AG | 1,782,734 | $14.5M | 0.00% | +1,554,869+682.4% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 1,698,757 | $13.8M | 0.04% | +470,798+38.3% | Added |
| Renaissance Technologies LLC | 1,622,840 | $13.2M | 0.02% | −432,500−21.0% | Reduced |
| Two Sigma Investments, LP | 1,614,579 | $13.1M | 0.02% | +399,880+32.9% | Added |
| Bank of America Corp | 1,594,866 | $13.0M | 0.00% | −68,624−4.1% | Reduced |
| Deutsche Bank AG | 1,567,645 | $12.8M | 0.00% | +830,718+112.7% | Added |
| Charles Schwab Investment Management Inc | 1,446,619 | $11.8M | 0.00% | +879,081+154.9% | Added |
| Prudential Financial Inc | 1,434,204 | $11.7M | 0.01% | −122,425−7.9% | Reduced |
| Northern Trust Corp | 1,363,129 | $11.1M | 0.00% | +69,599+5.4% | Added |
| Legal & General Group Plc | 1,357,427 | $11.0M | 0.00% | −446,776−24.8% | Reduced |
| Kennedy Capital Management, Inc. | 1,211,583 | $9.86M | 0.22% | +395,436+48.5% | Added |
| Voloridge Investment Management, LLC | 1,034,553 | $8.42M | 0.03% | +40,172+4.0% | Added |
| Knott David M Jr | 1,015,000 | $8.26M | 3.46% | −45,000−4.2% | Reduced |
| AQR Capital Management LLC | 983,600 | $8.01M | 0.01% | −65,393−6.2% | Reduced |
| Acadian Asset Management LLC | 921,103 | $7.50M | 0.01% | +537,866+140.3% | Added |
| Jane Street Group, LLC | 913,758 | $7.44M | 0.01% | +882,593+2,832.0% | Added |
| JPMorgan Chase & Co | 905,076 | $7.37M | 0.00% | −127,186−12.3% | Reduced |
| Two Sigma Advisers, LP | 893,242 | $7.27M | 0.01% | −163,537−15.5% | Reduced |
| Essex Investment Management Co LLC | 750,034 | $6.11M | 0.93% | +24,260+3.3% | Added |
| Federated Hermes, Inc. | 704,383 | $5.73M | 0.01% | +13,002+1.9% | Added |
| CenterBook Partners LP | 698,204 | $5.68M | 0.28% | −896,025−56.2% | Reduced |
| Squarepoint Ops LLC | 679,081 | $5.53M | 0.01% | +394,514+138.6% | Added |
| Walleye Capital LLC | 623,962 | $5.08M | 0.04% | +380,687+156.5% | Added |
| Jump Financial, LLC | 603,244 | $4.91M | 0.06% | −153,159−20.2% | Reduced |
| EAM Investors, LLC | 603,101 | $4.85M | 0.56% | +16,236+2.8% | Added |
| Invesco Ltd. | 583,108 | $4.75M | 0.00% | +496,914+576.5% | Added |
| BNP Paribas Arbitrage, SA | 581,719 | $4.74M | 0.00% | +565,409+3,466.6% | Added |
| Wellington Management Group LLP | 580,962 | $4.73M | 0.00% | +181,671+45.5% | Added |
| Millennium Management LLC | 524,749 | $4.27M | 0.00% | −2,408,871−82.1% | Reduced |
| Redmile Group, LLC | 451,099 | $3.67M | 0.36% | 00.0% | Unchanged |
| Bank of New York Mellon Corp | 439,838 | $3.58M | 0.00% | +62,711+16.6% | Added |
| Citadel Advisors LLC | 437,612 | $3.56M | 0.00% | +437,612 | New |
| Divisadero Street Capital Management, LP | 406,334 | $3.31M | 0.15% | +406,334 | New |
| Voya Investment Management LLC | 400,079 | $3.26M | 0.00% | +358,689+866.6% | Added |
| Canada Pension Plan Investment Board | 375,700 | $3.06M | 0.00% | +375,700 | New |
| FMR LLC | 360,178 | $2.93M | 0.00% | +33,758+10.3% | Added |
| State of Wisconsin Investment Board | 350,529 | $2.85M | 0.01% | +72,509+26.1% | Added |
| Granahan Investment Management Inc | 350,168 | $2.85M | 0.12% | +350,168 | New |
| Barclays PLC | 346,639 | $2.82M | 0.00% | −77,609−18.3% | Reduced |
| Harvest Investment Services, LLC | 325,555 | $2.65M | 0.53% | +213,585+190.8% | Added |
| Swiss National Bank | 310,400 | $2.53M | 0.00% | +310,400 | New |
| Schonfeld Strategic Advisors LLC | 304,504 | $2.48M | 0.02% | −84,562−21.7% | Reduced |
| Caxton Associates LLP | 281,337 | $2.29M | 0.06% | +281,337 | New |
| IHT Wealth Management, LLC | 258,175 | $2.10M | 0.05% | −5,630−2.1% | Reduced |
| Healthcare of Ontario Pension Plan Trust Fund | 254,000 | $2.07M | 0.00% | +2,000+0.8% | Added |
| Russell Investments Group, Ltd. | 251,378 | $2.05M | 0.00% | +128,189+104.1% | Added |
| Trexquant Investment LP | 229,420 | $1.87M | 0.02% | +229,420 | New |
| Legato Capital Management LLC | 216,805 | $1.76M | 0.19% | 00.0% | Unchanged |
| Rhumbline Advisers | 213,744 | $1.74M | 0.00% | −1,947−0.9% | Reduced |
| Raymond James Financial Inc | 205,213 | $1.67M | 0.00% | −3,933−1.9% | Reduced |
| Commonwealth Equity Services, LLC | 197,743 | $1.61M | 0.00% | 00.0% | Unchanged |
| UBS Asset Management Americas Inc | 183,459 | $1.49M | 0.00% | +145,840+387.7% | Added |
| Price T Rowe Associates Inc | 166,788 | $1.36M | 0.00% | +13,517+8.8% | Added |
| Algert Global LLC | 157,960 | $1.29M | 0.02% | +157,960 | New |
| Ameriprise Financial Inc | 154,168 | $1.25M | 0.00% | +5,140+3.4% | Added |
| Mackenzie Financial Corp | 152,161 | $1.24M | 0.00% | +14,069+10.2% | Added |
| California State Teachers Retirement System | 151,886 | $1.24M | 0.00% | +141,725+1,394.8% | Added |
| Alliancebernstein L.P. | 144,830 | $1.18M | 0.00% | 00.0% | Unchanged |
| Calamos Advisors LLC | 137,097 | $1.12M | 0.00% | +137,097 | New |
| Dark Forest Capital Management LP | 136,731 | $1.11M | 0.04% | +136,731 | New |
| Polen Capital Management LLC | 133,191 | $1.08M | 0.00% | +197+0.1% | Added |
| Brevan Howard Capital Management LP | 132,160 | $1.08M | 0.02% | −72,864−35.5% | Reduced |
| CWM Advisors, LLC | 128,494 | $1.05M | 0.10% | +128,494 | New |
| Creative Planning | 126,980 | $1.03M | 0.00% | +9,225+7.8% | Added |
| Globeflex Capital L P | 123,184 | $1.00M | 0.15% | +42,753+53.2% | Added |
| SEI Investments Co | 121,176 | $986.4K | 0.00% | +4,642+4.0% | Added |
| Deerfield Management Company, L.P. (Series C) | 120,900 | $984.1K | 0.02% | +98,326+435.6% | Added |
| Roundview Capital LLC | 120,000 | $976.8K | 0.06% | 00.0% | Unchanged |
| Engineers Gate Manager LP | 109,994 | $895.4K | 0.01% | +71,954+189.2% | Added |
| Franklin Resources Inc | 109,142 | $888.4K | 0.00% | +5,864+5.7% | Added |
| Fred Alger Management, LLC | 108,936 | $886.7K | 0.00% | +108,936 | New |
| Ieq Capital, LLC | 107,953 | $878.7K | 0.00% | −542−0.5% | Reduced |
| Principal Financial Group Inc | 105,493 | $858.7K | 0.00% | −48,444−31.5% | Reduced |
| Campbell & CO Investment Adviser LLC | 103,616 | $843.4K | 0.06% | −28,766−21.7% | Reduced |
| Thompson Siegel & Walmsley LLC | 100,884 | $821.0K | 0.01% | −165,503−62.1% | Reduced |
| Wells Fargo & Company | 97,196 | $791.2K | 0.00% | +16,830+20.9% | Added |
| Winton Group Ltd | 90,793 | $739.1K | 0.03% | +90,793 | New |
| MetLife Investment Management | 87,318 | $710.8K | 0.00% | 00.0% | Unchanged |
| ExodusPoint Capital Management, LP | 86,920 | $707.5K | 0.01% | +86,920 | New |
| SG Americas Securities, LLC | 83,214 | $677.0K | 0.00% | +63,921+331.3% | Added |
| Aquatic Capital Management LLC | 83,000 | $675.6K | 0.01% | +83,000 | New |
| Quarry LP | 82,500 | $671.5K | 0.16% | −80,000−49.2% | Reduced |
| Y-Intercept (Hong Kong) Ltd | 82,181 | $669.0K | 0.02% | −254,033−75.6% | Reduced |
| Susquehanna International Group, LLP | 81,471 | $663.2K | 0.00% | −324,731−79.9% | Reduced |
| OrbiMed Advisors LLC | 80,420 | $654.6K | 0.02% | 00.0% | Unchanged |
| Diadema Partners LP | 74,753 | $608.5K | 0.42% | +74,753 | New |
| HRT Financial LP | 72,543 | $590.0K | 0.00% | +72,543 | New |
| Round Rock Advisors, LLC | 63,772 | $582.2K | 0.09% | +63,772 | New |