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Xeris Biopharma Holdings, Inc.

XERS
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001867096

In the last 90 days, Xeris Biopharma Holdings, Inc. insiders filed 0 open-market purchases and 10 sales; 242 institutions reported holding it in 13F filings for Q2 2026, worth $857.1M in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Xeris Biopharma Holdings, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
231
+32 vs. Q2 2025
Shares held
97.0M
+6.99M (+7.8%) vs. Q2 2025
Total value
$789.3M
+$369.1M (+87.8%) vs. Q2 2025
New holders
59
77 more added
Sold out
27
61 more reduced

2 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting XERS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 231 institutions
Q1 2021: 103 institutionsQ2 2021: 94 institutionsQ3 2021: 71 institutionsQ4 2021: 92 institutionsQ1 2022: 103 institutionsQ2 2022: 103 institutionsQ3 2022: 101 institutionsQ4 2022: 97 institutionsQ1 2023: 92 institutionsQ2 2023: 105 institutionsQ3 2023: 111 institutionsQ4 2023: 120 institutionsQ1 2024: 142 institutionsQ2 2024: 135 institutionsQ3 2024: 144 institutionsQ4 2024: 162 institutionsQ1 2025: 199 institutionsQ2 2025: 201 institutionsQ3 2025: 231 institutionsQ4 2025: 227 institutionsQ1 2026: 239 institutionsQ2 2026: 242 institutions
Value heldQ3 2025: $789.3M
Q1 2021: $149.7MQ2 2021: $114.9MQ3 2021: $42.9MQ4 2021: $120.2MQ1 2022: $129.2MQ2 2022: $91.3MQ3 2022: $89.3MQ4 2022: $71.6MQ1 2023: $80.6MQ2 2023: $146.7MQ3 2023: $102.3MQ4 2023: $140.8MQ1 2024: $133.7MQ2 2024: $136.6MQ3 2024: $182.2MQ4 2024: $222.2MQ1 2025: $480.9MQ2 2025: $422.9MQ3 2025: $789.3MQ4 2025: $792.0MQ1 2026: $610.3MQ2 2026: $857.1M
Institutions holding XERS and their total value by quarter
QuarterHoldersValue
Q2 2026242$857.1M
Q1 2026239$610.3M
Q4 2025227$792.0M
Q3 2025231$789.3M
Q2 2025201$422.9M
Q1 2025199$480.9M
Q4 2024162$222.2M
Q3 2024144$182.2M
Q2 2024135$136.6M
Q1 2024142$133.7M
Q4 2023120$140.8M
Q3 2023111$102.3M
Q2 2023105$146.7M
Q1 202392$80.6M
Q4 202297$71.6M
Q3 2022101$89.3M
Q2 2022103$91.3M
Q1 2022103$129.2M
Q4 202192$120.2M
Q3 202171$42.9M
Q2 202194$114.9M
Q1 2021103$149.7M

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Xeris Biopharma Holdings, Inc.; share changes are against Q2 2025.

Institutions holding XERS in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
IFP Advisors, Inc20$1630.00%−60−75.0%Reduced
GAMMA Investing LLC24$1950.00%+24New
Steigerwald, Gordon & Koch Inc.37$3010.00%+37New
Caitong International Asset Management Co., Ltd80$6510.00%−1,256−94.0%Reduced
Sunbelt Securities, Inc.81$6590.00%+81New
Bessemer Group Inc68$1.00K0.00%+68New
Parkside Financial Bank & Trust155$1.26K0.00%00.0%Unchanged
Spurstone Advisory Services, LLC200$1.63K0.02%00.0%Unchanged
Global Retirement Partners, LLC300$2.44K0.00%−400−57.1%Reduced
Comerica Bank308$2.51K0.00%+308New
Optiver Holding B.V.336$2.73K0.00%+336New
Wealthspire Advisors, LLC354$2.88K0.00%+354New
Daiwa Securities Group Inc.404$3.00K0.00%00.0%Unchanged
Covestor Ltd321$3.00K0.00%+28+9.6%Added
Sterling Capital Management LLC372$3.03K0.00%+10+2.8%Added
Larson Financial Group LLC400$3.26K0.00%+400New
Rothschild Investment LLC420$3.42K0.00%00.0%Unchanged
Clearstead Advisors, LLC581$4.73K0.00%+17+3.0%Added
The PNC Financial Services Group, Inc.621$5.05K0.00%+27+4.5%Added
Signaturefd, LLC631$5.14K0.00%00.0%Unchanged
Massmutual Trust Co FSB894$7.28K0.00%+340+61.4%Added
Hillsdale Investment Management Inc.1,000$8.14K0.00%−300−23.1%Reduced
Activest Wealth Management1,000$8.14K0.00%00.0%Unchanged
Advisory Services Network, LLC1,000$8.14K0.00%+1,000New
True Wealth Design, LLC1,011$8.23K0.00%+44+4.6%Added
TSFG, LLC1,058$9.00K0.00%00.0%Unchanged
Essential Partners LLC1,427$11.6K0.00%+362+34.0%Added
Fortitude Family Office, LLC1,553$12.6K0.00%00.0%Unchanged
Allworth Financial LP1,765$14.4K0.00%−311−15.0%Reduced
EverSource Wealth Advisors, LLC1,877$15.3K0.00%−314−14.3%Reduced
SBI Securities Co., Ltd.1,913$15.6K0.00%+6+0.3%Added
Creative Financial Designs Inc2,200$17.9K0.00%+300+15.8%Added
Nisa Investment Advisors, LLC2,204$17.9K0.00%00.0%Unchanged
Farther Finance Advisors, LLC2,381$19.4K0.00%+2,200+1,215.5%Added
Jones Financial Companies LLLP2,781$22.7K0.00%+1,303+88.2%Added
GF Fund Management Co. Ltd.3,474$28.3K0.00%−343−9.0%Reduced
Webster Bank, N. A.4,000$32.6K0.00%+1,000+33.3%Added
Truvestments Capital LLC4,139$33.7K0.01%+566+15.8%Added
Quest Partners LLC4,300$35.0K0.00%+4,300New
Tower Research Capital LLC (TRC)4,454$36.3K0.00%−12,941−74.4%Reduced
Amalgamated Bank4,834$39.0K0.00%00.0%Unchanged
Group One Trading, L.P.6,024$49.0K0.00%+6,024New
Mirae Asset Global Investments Co., Ltd.6,243$50.8K0.00%+56+0.9%Added
CIBC Private Wealth Group, LLC6,664$54.2K0.00%00.0%Unchanged
Northwestern Mutual Wealth Management Co7,789$63.4K0.00%+5,000+179.3%Added
State of Alaska, Department of Revenue8,457$68.0K0.00%+8,457New
O'Shaughnessy Asset Management, LLC10,160$82.7K0.00%+10,160New
Mariner, LLC10,404$84.7K0.00%−1,333−11.4%Reduced
Mercer Global Advisors Inc10,466$85.2K0.00%+10,466New
Pallas Capital Advisors LLC11,027$89.8K0.00%+22+0.2%Added
Apella Capital, LLC10,000$91.4K0.00%00.0%Unchanged
Captrust Financial Advisors11,904$96.9K0.00%+1,098+10.2%Added
Xponance, Inc.11,985$97.6K0.00%+525+4.6%Added
Verition Fund Management LLC12,229$99.5K0.00%+12,229New
R Squared Ltd12,709$103.5K0.04%+12,709New
Ameritas Investment Partners, Inc.12,827$104.4K0.00%−1,378−9.7%Reduced
State of Wyoming12,900$105.0K0.01%−22,306−63.4%Reduced
Universal- Beteiligungs- und Servicegesellschaft mbH13,155$107.1K0.00%+13,155New
Empirical Financial Services, LLC d.b.a. Empirical Wealth Management13,650$111.1K0.00%00.0%Unchanged
Avenue 1 Advisors, LLC14,163$115.3K0.04%00.0%Unchanged
Atom Investors LP14,968$121.8K0.01%−3,187−17.6%Reduced
Prelude Capital Management, LLC15,500$126.2K0.01%00.0%Unchanged
JustInvest LLC15,561$126.7K0.00%+15,561New
Landscape Capital Management, L.L.C.15,709$127.9K0.01%00.0%Unchanged
SRS Capital Advisors, Inc.15,859$129.1K0.00%+15,859New
CIBC Bancorp USA Inc.16,367$133.2K0.00%+16,367New
Jacksonville Wealth Management, LLC17,000$138.4K0.10%+17,000New
Susquehanna Fundamental Investments, LLC17,087$139.1K0.01%00.0%Unchanged
Capstone Investment Advisors, LLC17,130$139.4K0.00%+17,130New
Persistent Asset Partners Ltd17,202$140.0K0.10%+17,202New
Victory Capital Management Inc17,255$140.5K0.00%−353−2.0%Reduced
Quadrature Capital Ltd17,289$140.8K0.00%−29,467−63.0%Reduced
Rafferty Asset Management, LLC17,411$141.7K0.00%−8,492−32.8%Reduced
Quantinno Capital Management LP17,694$144.0K0.00%+5,123+40.8%Added
Modern Wealth Management, LLC17,704$144.1K0.00%00.0%Unchanged
Los Angeles Capital Management LLC17,901$145.7K0.00%−2,481−12.2%Reduced
Numerai GP LLC18,507$150.6K0.02%+18,507New
Aigen Investment Management, LP19,129$155.7K0.02%+19,129New
Toroso Investments, LLC19,485$158.6K0.00%+19,485New
Aspiriant, LLC20,000$162.8K0.00%+20,000New
Verdence Capital Advisors LLC17,549$163.4K0.01%+17,549New
Sunpointe, LLC21,000$170.9K0.06%00.0%Unchanged
Van Hulzen Asset Management, LLC22,182$180.6K0.01%+5,058+29.5%Added
Pictet Asset Management Holding SA23,196$188.8K0.00%+23,196New
Petrus Trust Company, LTA24,351$198.2K0.02%+24,351New
Omers Administration Corp24,600$200.2K0.00%+24,600New
Skandinaviska Enskilda Banken AB (publ)25,000$203.5K0.00%+25,000New
Virtus Investment Advisers, Inc.25,744$209.6K0.06%+4,470+21.0%Added
Janney Montgomery Scott LLC26,200$213.0K0.00%+1,000+4.0%Added
Axq Capital, LP26,356$214.5K0.08%+26,356New
Asset Management Group, Inc.26,480$215.5K0.04%00.0%Unchanged
Profund Advisors LLC26,564$216.2K0.01%−15,516−36.9%Reduced
Baader Bank INC28,312$230.1K0.02%+28,312New
China Universal Asset Management Co., Ltd.28,305$230.4K0.02%−3,862−12.0%Reduced
Cerity Partners LLC31,033$252.6K0.00%+2,905+10.3%Added
Wealth Enhancement Advisory Services, LLC31,107$257.6K0.00%+4,349+16.3%Added
ProShare Advisors LLC32,007$260.5K0.00%−4,716−12.8%Reduced
Diversified Trust Co32,062$261.0K0.01%−138,173−81.2%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)32,652$265.8K0.00%+29,353+889.8%Added
Semanteon Capital Management, LP32,925$268.0K0.34%+32,925New