Xeris Biopharma Holdings, Inc.
XERS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001867096
In the last 90 days, Xeris Biopharma Holdings, Inc. insiders filed 0 open-market purchases and 9 sales; 242 institutions reported holding it in 13F filings for Q2 2026, worth $857.1M in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Xeris Biopharma Holdings, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 239
- +17 vs. Q4 2025
- Shares held
- 105.2M
- +16.3M (+18.4%) vs. Q4 2025
- Total value
- $610.3M
- −$87.5M (−12.5%) vs. Q4 2025
- New holders
- 47
- 100 more added
- Sold out
- 30
- 57 more reduced
5 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting XERS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 242 | $857.1M |
| Q1 2026 | 239 | $610.3M |
| Q4 2025 | 227 | $792.0M |
| Q3 2025 | 231 | $789.3M |
| Q2 2025 | 201 | $422.9M |
| Q1 2025 | 199 | $480.9M |
| Q4 2024 | 162 | $222.2M |
| Q3 2024 | 144 | $182.2M |
| Q2 2024 | 135 | $136.6M |
| Q1 2024 | 142 | $133.7M |
| Q4 2023 | 120 | $140.8M |
| Q3 2023 | 111 | $102.3M |
| Q2 2023 | 105 | $146.7M |
| Q1 2023 | 92 | $80.6M |
| Q4 2022 | 97 | $71.6M |
| Q3 2022 | 101 | $89.3M |
| Q2 2022 | 103 | $91.3M |
| Q1 2022 | 103 | $129.2M |
| Q4 2021 | 92 | $120.2M |
| Q3 2021 | 71 | $42.9M |
| Q2 2021 | 94 | $114.9M |
| Q1 2021 | 103 | $149.7M |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Xeris Biopharma Holdings, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| BlackRock, Inc. | 12,945,785 | $75.1M | 0.00% | +306,467+2.4% | Added |
| D. E. Shaw & Co., Inc. | 7,788,811 | $45.2M | 0.04% | +213,961+2.8% | Added |
| Vanguard Capital Management LLC | 6,980,882 | $40.5M | 0.00% | +6,980,882 | New |
| State Street Corp | 4,658,174 | $27.0M | 0.00% | +541,250+13.1% | Added |
| Geode Capital Management, LLC | 4,290,629 | $24.9M | 0.00% | +14,640+0.3% | Added |
| Qube Research & Technologies Ltd | 4,114,425 | $23.9M | 0.03% | +616,228+17.6% | Added |
| Rosalind Advisors, Inc. | 3,231,700 | $18.7M | 7.68% | +1,120,000+53.0% | Added |
| Nuveen, LLC | 2,916,598 | $16.9M | 0.00% | +109,792+3.9% | Added |
| Vanguard Portfolio Management LLC | 2,665,608 | $15.5M | 0.00% | +2,665,608 | New |
| Morgan Stanley | 2,572,654 | $14.9M | 0.00% | −135,129−5.0% | Reduced |
| Millennium Management LLC | 2,265,974 | $13.1M | 0.01% | +1,406,923+163.8% | Added |
| Wellington Management Group LLP | 2,171,354 | $12.6M | 0.00% | −115,244−5.0% | Reduced |
| Two Sigma Investments, LP | 1,924,202 | $11.2M | 0.01% | +191,535+11.1% | Added |
| Armistice Capital, LLC | 1,909,838 | $11.1M | 0.37% | +1,909,838 | New |
| Legal & General Group Plc | 1,908,289 | $11.1M | 0.00% | +512,024+36.7% | Added |
| Parkman Healthcare Partners LLC | 1,721,264 | $9.98M | 1.04% | +29,679+1.8% | Added |
| UBS Group AG | 1,646,378 | $9.55M | 0.00% | +1,044,544+173.6% | Added |
| Goldman Sachs Group Inc | 1,613,650 | $9.36M | 0.00% | +45,229+2.9% | Added |
| Northern Trust Corp | 1,444,617 | $8.38M | 0.00% | +57,788+4.2% | Added |
| AQR Capital Management LLC | 1,394,376 | $8.09M | 0.00% | +436,797+45.6% | Added |
| Voss Capital, LLC | 1,386,927 | $8.04M | 0.46% | +1,015,218+273.1% | Added |
| Charles Schwab Investment Management Inc | 1,359,657 | $7.89M | 0.00% | −44,167−3.1% | Reduced |
| CenterBook Partners LP | 1,248,621 | $7.24M | 0.39% | −142,969−10.3% | Reduced |
| Kennedy Capital Management, Inc. | 1,240,692 | $7.20M | 0.15% | +26,723+2.2% | Added |
| Algert Global LLC | 1,156,958 | $6.71M | 0.10% | +438,114+60.9% | Added |
| Vanguard Fiduciary Trust Co | 1,133,902 | $6.58M | 0.00% | +1,133,902 | New |
| Knott David M Jr | 1,060,000 | $6.15M | 3.66% | +90,000+9.3% | Added |
| Ishara Investments LP | 1,025,000 | $5.95M | 6.00% | +225,000+28.1% | Added |
| Granahan Investment Management Inc | 921,854 | $5.35M | 0.26% | −301,550−24.6% | Reduced |
| Driehaus Capital Management LLC | 902,740 | $5.24M | 0.04% | −2,077,827−69.7% | Reduced |
| Bank of America Corp | 874,397 | $5.07M | 0.00% | +156,483+21.8% | Added |
| Federated Hermes, Inc. | 856,813 | $4.97M | 0.01% | +1,925+0.2% | Added |
| Trexquant Investment LP | 833,217 | $4.83M | 0.03% | +619,636+290.1% | Added |
| Essex Investment Management Co LLC | 747,769 | $4.34M | 0.69% | +13,237+1.8% | Added |
| Jane Street Group, LLC | 725,616 | $4.21M | 0.00% | +547,794+308.1% | Added |
| Citadel Advisors LLC | 681,634 | $3.95M | 0.00% | +271,814+66.3% | Added |
| UBS Asset Management Americas Inc | 668,074 | $3.87M | 0.00% | +16,629+2.6% | Added |
| Voya Investment Management LLC | 625,310 | $3.63M | 0.00% | +166,981+36.4% | Added |
| Deutsche Bank AG | 623,012 | $3.61M | 0.00% | −317,580−33.8% | Reduced |
| Squarepoint Ops LLC | 614,550 | $3.56M | 0.01% | +131,718+27.3% | Added |
| JPMorgan Chase & Co | 612,479 | $3.43M | 0.00% | −282,580−31.6% | Reduced |
| SEI Investments Co | 579,210 | $3.36M | 0.00% | +179,863+45.0% | Added |
| FMR LLC | 513,076 | $2.98M | 0.00% | +73,371+16.7% | Added |
| Healthcare of Ontario Pension Plan Trust Fund | 464,084 | $2.69M | 0.00% | −73,399−13.7% | Reduced |
| Renaissance Technologies LLC | 452,860 | $2.63M | 0.00% | −166,800−26.9% | Reduced |
| Bank of New York Mellon Corp | 426,285 | $2.47M | 0.00% | −7,977−1.8% | Reduced |
| Connor, Clark & Lunn Investment Management Ltd. | 407,625 | $2.36M | 0.01% | −651,067−61.5% | Reduced |
| Russell Investments Group, Ltd. | 384,195 | $2.23M | 0.00% | +19,409+5.3% | Added |
| IHT Wealth Management, LLC | 376,476 | $2.18M | 0.05% | +112,945+42.9% | Added |
| Canada Pension Plan Investment Board | 374,800 | $2.17M | 0.00% | −15,800−4.0% | Reduced |
| Voloridge Investment Management, LLC | 370,116 | $2.15M | 0.01% | −441,013−54.4% | Reduced |
| Swiss National Bank | 328,300 | $1.90M | 0.00% | +9,900+3.1% | Added |
| State of Wisconsin Investment Board | 308,546 | $1.79M | 0.00% | −48,907−13.7% | Reduced |
| Schonfeld Strategic Advisors LLC | 296,431 | $1.72M | 0.01% | +61,708+26.3% | Added |
| Janus Henderson Group PLC | 295,489 | $1.71M | 0.00% | +225,602+322.8% | Added |
| Susquehanna International Group, LLP | 286,071 | $1.66M | 0.00% | +168,716+143.8% | Added |
| Man Group plc | 276,422 | $1.60M | 0.00% | +228,647+478.6% | Added |
| BNP Paribas Arbitrage, SA | 262,787 | $1.52M | 0.00% | +4,419+1.7% | Added |
| Apella Capital, LLC | 235,897 | $1.50M | 0.02% | −10,000−4.1% | Reduced |
| Royce & Associates LP | 256,087 | $1.49M | 0.01% | +256,087 | New |
| Rice Hall James & Associates, LLC | 251,066 | $1.46M | 0.08% | +251,066 | New |
| Legato Capital Management LLC | 234,144 | $1.36M | 0.12% | −3,287−1.4% | Reduced |
| Group One Trading, L.P. | 218,145 | $1.27M | 0.04% | +94,584+76.5% | Added |
| Price T Rowe Associates Inc | 209,034 | $1.21M | 0.00% | +35,571+20.5% | Added |
| Principal Financial Group Inc | 208,507 | $1.21M | 0.00% | +57,948+38.5% | Added |
| Raymond James Financial Inc | 208,273 | $1.21M | 0.00% | −3,146−1.5% | Reduced |
| Emerald Mutual Fund Advisers Trust | 207,543 | $1.20M | 0.06% | +207,543 | New |
| F/M Investments LLC | 207,543 | $1.20M | 0.08% | +207,543 | New |
| Caption Management, LLC | 205,000 | $1.19M | 0.06% | +205,000 | New |
| Commonwealth Equity Services, LLC | 203,116 | $1.18M | 0.00% | +5,301+2.7% | Added |
| Alliancebernstein L.P. | 145,336 | $1.14M | 0.00% | +506+0.3% | Added |
| Rhumbline Advisers | 191,067 | $1.11M | 0.00% | +1,500+0.8% | Added |
| Engineers Gate Manager LP | 185,911 | $1.08M | 0.01% | +96,507+107.9% | Added |
| California State Teachers Retirement System | 180,339 | $1.05M | 0.00% | +29,168+19.3% | Added |
| HRT Financial LP | 171,102 | $992.0K | 0.00% | −161,224−48.5% | Reduced |
| Y-Intercept (Hong Kong) Ltd | 161,793 | $938.4K | 0.02% | +71,148+78.5% | Added |
| Ameriprise Financial Inc | 142,148 | $824.5K | 0.00% | −1,315−0.9% | Reduced |
| Barclays PLC | 138,553 | $803.6K | 0.00% | −224,198−61.8% | Reduced |
| Arrowstreet Capital, Limited Partnership | 133,760 | $775.8K | 0.00% | −81,026−37.7% | Reduced |
| Creative Planning | 133,285 | $773.1K | 0.00% | +16,747+14.4% | Added |
| Diadema Partners LP | 132,746 | $769.9K | 0.32% | −37,822−22.2% | Reduced |
| Quarry LP | 125,000 | $725.0K | 0.15% | +45,000+56.3% | Added |
| Globeflex Capital L P | 123,184 | $714.5K | 0.11% | 00.0% | Unchanged |
| SG Americas Securities, LLC | 121,911 | $707.0K | 0.00% | +11,731+10.6% | Added |
| Tudor Investment Corp Et Al | 107,414 | $623.0K | 0.00% | +85,228+384.2% | Added |
| Panagora Asset Management Inc | 104,744 | $607.5K | 0.00% | +104,744 | New |
| Palo Alto Investors LP | 104,410 | $605.6K | 0.09% | +104,410 | New |
| Winton Group Ltd | 104,240 | $604.6K | 0.02% | +39,643+61.4% | Added |
| Vanguard Asset Management, Ltd | 103,555 | $600.6K | 0.00% | +103,555 | New |
| Invesco Ltd. | 103,294 | $599.1K | 0.00% | −8,836−7.9% | Reduced |
| Gsa Capital Partners LLP | 101,438 | $588.0K | 0.04% | +66,773+192.6% | Added |
| Twinbeech Capital LP | 97,200 | $563.8K | 0.06% | +97,200 | New |
| Round Rock Advisors, LLC | 96,816 | $561.5K | 0.09% | 00.0% | Unchanged |
| EntryPoint Capital, LLC | 96,210 | $558.0K | 0.16% | +28,127+41.3% | Added |
| LPL Financial LLC | 93,861 | $544.4K | 0.00% | +9,000+10.6% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 93,302 | $541.2K | 0.00% | +27,535+41.9% | Added |
| Jefferies Financial Group Inc. | 87,800 | $509.2K | 0.01% | 00.0% | Unchanged |
| Citigroup Inc | 87,325 | $506.5K | 0.00% | −11,421−11.6% | Reduced |
| Thompson Siegel & Walmsley LLC | 86,320 | $501.0K | 0.01% | −14,564−14.4% | Reduced |
| Ieq Capital, LLC | 81,630 | $473.5K | 0.00% | −4,890−5.7% | Reduced |