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Xeris Biopharma Holdings, Inc.

XERS
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001867096

In the last 90 days, Xeris Biopharma Holdings, Inc. insiders filed 0 open-market purchases and 8 sales; 242 institutions reported holding it in 13F filings for Q2 2026, worth $857.1M in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Xeris Biopharma Holdings, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
239
+17 vs. Q4 2025
Shares held
105.2M
+16.3M (+18.4%) vs. Q4 2025
Total value
$610.3M
−$87.5M (−12.5%) vs. Q4 2025
New holders
47
100 more added
Sold out
30
57 more reduced

5 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting XERS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 239 institutions
Q1 2021: 103 institutionsQ2 2021: 94 institutionsQ3 2021: 71 institutionsQ4 2021: 92 institutionsQ1 2022: 103 institutionsQ2 2022: 103 institutionsQ3 2022: 101 institutionsQ4 2022: 97 institutionsQ1 2023: 92 institutionsQ2 2023: 105 institutionsQ3 2023: 111 institutionsQ4 2023: 120 institutionsQ1 2024: 142 institutionsQ2 2024: 135 institutionsQ3 2024: 144 institutionsQ4 2024: 162 institutionsQ1 2025: 199 institutionsQ2 2025: 201 institutionsQ3 2025: 231 institutionsQ4 2025: 227 institutionsQ1 2026: 239 institutionsQ2 2026: 242 institutions
Value heldQ1 2026: $610.3M
Q1 2021: $149.7MQ2 2021: $114.9MQ3 2021: $42.9MQ4 2021: $120.2MQ1 2022: $129.2MQ2 2022: $91.3MQ3 2022: $89.3MQ4 2022: $71.6MQ1 2023: $80.6MQ2 2023: $146.7MQ3 2023: $102.3MQ4 2023: $140.8MQ1 2024: $133.7MQ2 2024: $136.6MQ3 2024: $182.2MQ4 2024: $222.2MQ1 2025: $480.9MQ2 2025: $422.9MQ3 2025: $789.3MQ4 2025: $792.0MQ1 2026: $610.3MQ2 2026: $857.1M
Institutions holding XERS and their total value by quarter
QuarterHoldersValue
Q2 2026242$857.1M
Q1 2026239$610.3M
Q4 2025227$792.0M
Q3 2025231$789.3M
Q2 2025201$422.9M
Q1 2025199$480.9M
Q4 2024162$222.2M
Q3 2024144$182.2M
Q2 2024135$136.6M
Q1 2024142$133.7M
Q4 2023120$140.8M
Q3 2023111$102.3M
Q2 2023105$146.7M
Q1 202392$80.6M
Q4 202297$71.6M
Q3 2022101$89.3M
Q2 2022103$91.3M
Q1 2022103$129.2M
Q4 202192$120.2M
Q3 202171$42.9M
Q2 202194$114.9M
Q1 2021103$149.7M

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Xeris Biopharma Holdings, Inc.; share changes are against Q4 2025.

Institutions holding XERS in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Franklin Resources Inc80,217$465.3K0.00%−41,211−33.9%Reduced
Magnetar Financial LLC79,302$460.0K0.00%+79,302New
MetLife Investment Management76,763$445.2K0.00%−4,831−5.9%Reduced
Vanguard Global Advisers, LLC76,511$443.8K0.00%+76,511New
Western Wealth Management, LLC75,675$438.9K0.02%00.0%Unchanged
Mirae Asset Global ETFs Holdings Ltd.73,870$428.4K0.00%+2,559+3.6%Added
Teachers Retirement System of the State of Kentucky72,907$423.0K0.00%00.0%Unchanged
Manufacturers Life Insurance Company, The72,804$422.3K0.00%+27,003+59.0%Added
Penn Capital Management Co Inc68,896$399.6K0.03%+20,832+43.3%Added
Integrated Quantitative Investments LLC66,170$383.8K0.07%00.0%Unchanged
CWM, LLC64,180$372.2K0.00%+8,824+15.9%Added
Wells Fargo & Company58,307$338.2K0.00%−112,489−65.9%Reduced
Prudential Financial Inc57,139$331.4K0.00%−561,810−90.8%Reduced
State of New Jersey Common Pension Fund D56,706$328.9K0.00%+56,706New
Advisor Group Holdings, Inc.54,756$317.6K0.00%+2,471+4.7%Added
Weiss Asset Management LP50,001$290.0K0.01%00.0%Unchanged
Palogic Value Management, L.P.50,000$290.0K0.13%+50,000New
Voleon Capital Management LP46,508$269.7K0.01%+46,508New
AlphaCentric Advisors LLC45,886$266.1K0.27%+2,494+5.7%Added
Arizona State Retirement System45,575$264.3K0.00%+306+0.7%Added
Cetera Investment Advisers44,397$257.5K0.00%+5,750+14.9%Added
Royal Bank of Canada43,610$253.0K0.00%+4,974+12.9%Added
New York State Common Retirement Fund43,422$251.8K0.00%00.0%Unchanged
Gotham Asset Management, LLC43,257$250.9K0.00%+7,845+22.2%Added
China Universal Asset Management Co., Ltd.42,245$245.0K0.02%+15,208+56.2%Added
Savvy Advisors, Inc.41,468$240.5K0.01%+1,003+2.5%Added
Profund Advisors LLC41,133$238.6K0.01%+2,186+5.6%Added
Police & Firemen's Retirement System of New Jersey40,738$236.3K0.00%00.0%Unchanged
Vanguard Investments Australia, Ltd.40,202$233.2K0.00%+40,202New
Stonepine Capital Management, LLC40,030$232.2K0.20%+40,030New
Wealth Enhancement Advisory Services, LLC37,180$224.6K0.00%+6,075+19.5%Added
Virtus Investment Advisers, Inc.38,030$220.6K0.06%+928+2.5%Added
State Board of Administration of Florida Retirement System37,970$220.2K0.00%00.0%Unchanged
DRW Securities, LLC36,807$213.5K0.01%+36,807New
KLP Kapitalforvaltning AS36,800$213.4K0.00%+3,400+10.2%Added
Intech Investment Management LLC36,241$210.2K0.00%−28,849−44.3%Reduced
Persistent Asset Partners Ltd35,661$206.8K0.08%−9,948−21.8%Reduced
Cambridge Investment Research Advisors, Inc.34,674$201.0K0.00%+32+0.1%Added
Aigen Investment Management, LP32,521$188.6K0.05%+20,259+165.2%Added
Diversified Trust Co32,062$186.0K0.00%00.0%Unchanged
HSBC Holdings PLC31,175$182.7K0.00%+31,175New
Quantinno Capital Management LP30,971$179.6K0.00%+6,275+25.4%Added
Fox Run Management, L.L.C.31,721$177.6K0.03%+5,547+21.2%Added
Cerity Partners LLC30,583$177.4K0.00%+1,005+3.4%Added
ProShare Advisors LLC30,480$176.8K0.00%−4,910−13.9%Reduced
Pictet Asset Management Holding SA29,999$174.0K0.00%+6,803+29.3%Added
Quantbot Technologies LP28,064$162.8K0.01%−49,584−63.9%Reduced
Graham Capital Management, L.P.27,162$157.5K0.01%+27,162New
Asset Management Group, Inc.26,480$153.6K0.02%00.0%Unchanged
ExodusPoint Capital Management, LP25,685$149.0K0.00%+25,685New
Janney Montgomery Scott LLC25,200$146.0K0.00%+750+3.1%Added
Rafferty Asset Management, LLC24,247$140.6K0.00%−9,442−28.0%Reduced
Mariner, LLC23,081$133.9K0.00%+23,081New
Mirabella Financial Services LLP22,483$130.4K0.01%+22,483New
Teacher Retirement System of Texas21,122$122.5K0.00%−2,814−11.8%Reduced
Dark Forest Capital Management LP21,070$122.2K0.01%−30,973−59.5%Reduced
Entropy Technologies, LP20,432$118.5K0.01%+20,432New
XTX Topco Ltd20,272$117.6K0.00%+20,272New
Campbell & CO Investment Adviser LLC20,027$116.2K0.01%−27,427−57.8%Reduced
Aspiriant, LLC20,000$116.0K0.00%00.0%Unchanged
Van Hulzen Asset Management, LLC19,382$112.4K0.01%−1,000−4.9%Reduced
Kemnay Advisory Services Inc.18,359$106.5K0.02%+9,879+116.5%Added
Victory Capital Management Inc18,331$106.3K0.00%+491+2.8%Added
Toroso Investments, LLC18,159$105.3K0.00%+18,159New
Palumbo Wealth Management LLC17,788$103.2K0.03%−6,561−26.9%Reduced
STRS Ohio17,600$102.1K0.00%−47,900−73.1%Reduced
Jacksonville Wealth Management, LLC17,000$98.6K0.07%00.0%Unchanged
Mercer Global Advisors Inc16,988$98.5K0.00%+16,988New
Neuberger Berman Group LLC16,725$97.0K0.00%+16,725New
Brevan Howard Capital Management LP15,753$91.4K0.00%−76,663−83.0%Reduced
Landscape Capital Management, L.L.C.15,709$91.1K0.01%00.0%Unchanged
Captrust Financial Advisors14,815$85.9K0.00%+2,999+25.4%Added
CIBC Bancorp USA Inc.14,673$85.1K0.00%+14,673New
Xponance, Inc.14,325$83.1K0.00%+2,213+18.3%Added
Universal- Beteiligungs- und Servicegesellschaft mbH14,192$82.3K0.00%00.0%Unchanged
Chicago Partners Investment Group LLC13,493$81.5K0.00%+13,493New
R Squared Ltd13,802$80.1K0.04%+13,802New
Empirical Financial Services, LLC d.b.a. Empirical Wealth Management13,650$79.2K0.00%−2,420−15.1%Reduced
Ameritas Investment Partners, Inc.12,827$74.4K0.00%00.0%Unchanged
Pallas Capital Advisors LLC11,121$64.5K0.00%+118+1.1%Added
IMC-Chicago, LLC10,881$63.1K0.00%+10,881New
Skopos Labs, Inc.10,534$61.1K0.00%−1,661−13.6%Reduced
State of Wyoming10,420$60.4K0.01%−32,038−75.5%Reduced
Scientech Research LLC10,414$60.4K0.05%+10,414New
Kingsview Wealth Management, LLC10,000$58.0K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)9,742$56.5K0.00%−998−9.3%Reduced
Mirae Asset Global Investments Co., Ltd.8,655$50.2K0.00%+592+7.3%Added
State of Alaska, Department of Revenue8,457$49.0K0.00%00.0%Unchanged
Truvestments Capital LLC8,118$47.1K0.01%00.0%Unchanged
Jones Financial Companies LLLP6,207$33.5K0.00%+500+8.8%Added
KBC Group NV4,573$27.0K0.00%+4,573New
GF Fund Management Co. Ltd.3,710$21.5K0.00%+450+13.8%Added
BNP PARIBAS ASSET MANAGEMENT Holding S.A.3,105$18.0K0.00%+752+32.0%Added
Rockefeller Capital Management L.P.2,964$17.2K0.00%+2,370+399.0%Added
Northwestern Mutual Wealth Management Co2,789$16.2K0.00%−32−1.1%Reduced
Farther Finance Advisors, LLC2,469$14.9K0.00%−102−4.0%Reduced
Allworth Financial LP2,315$13.4K0.00%+629+37.3%Added
Nisa Investment Advisors, LLC2,204$12.8K0.00%00.0%Unchanged
Creative Financial Designs Inc2,200$12.8K0.00%00.0%Unchanged
SRS Capital Advisors, Inc.2,017$11.9K0.00%+385+23.6%Added