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Xeris Biopharma Holdings, Inc.

XERS
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001867096

In the last 90 days, Xeris Biopharma Holdings, Inc. insiders filed 0 open-market purchases and 8 sales; 242 institutions reported holding it in 13F filings for Q2 2026, worth $857.1M in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Xeris Biopharma Holdings, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
239
+17 vs. Q4 2025
Shares held
105.2M
+16.3M (+18.4%) vs. Q4 2025
Total value
$610.3M
−$87.5M (−12.5%) vs. Q4 2025
New holders
47
100 more added
Sold out
30
57 more reduced

5 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting XERS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 239 institutions
Q1 2021: 103 institutionsQ2 2021: 94 institutionsQ3 2021: 71 institutionsQ4 2021: 92 institutionsQ1 2022: 103 institutionsQ2 2022: 103 institutionsQ3 2022: 101 institutionsQ4 2022: 97 institutionsQ1 2023: 92 institutionsQ2 2023: 105 institutionsQ3 2023: 111 institutionsQ4 2023: 120 institutionsQ1 2024: 142 institutionsQ2 2024: 135 institutionsQ3 2024: 144 institutionsQ4 2024: 162 institutionsQ1 2025: 199 institutionsQ2 2025: 201 institutionsQ3 2025: 231 institutionsQ4 2025: 227 institutionsQ1 2026: 239 institutionsQ2 2026: 242 institutions
Value heldQ1 2026: $610.3M
Q1 2021: $149.7MQ2 2021: $114.9MQ3 2021: $42.9MQ4 2021: $120.2MQ1 2022: $129.2MQ2 2022: $91.3MQ3 2022: $89.3MQ4 2022: $71.6MQ1 2023: $80.6MQ2 2023: $146.7MQ3 2023: $102.3MQ4 2023: $140.8MQ1 2024: $133.7MQ2 2024: $136.6MQ3 2024: $182.2MQ4 2024: $222.2MQ1 2025: $480.9MQ2 2025: $422.9MQ3 2025: $789.3MQ4 2025: $792.0MQ1 2026: $610.3MQ2 2026: $857.1M
Institutions holding XERS and their total value by quarter
QuarterHoldersValue
Q2 2026242$857.1M
Q1 2026239$610.3M
Q4 2025227$792.0M
Q3 2025231$789.3M
Q2 2025201$422.9M
Q1 2025199$480.9M
Q4 2024162$222.2M
Q3 2024144$182.2M
Q2 2024135$136.6M
Q1 2024142$133.7M
Q4 2023120$140.8M
Q3 2023111$102.3M
Q2 2023105$146.7M
Q1 202392$80.6M
Q4 202297$71.6M
Q3 2022101$89.3M
Q2 2022103$91.3M
Q1 2022103$129.2M
Q4 202192$120.2M
Q3 202171$42.9M
Q2 202194$114.9M
Q1 2021103$149.7M

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Xeris Biopharma Holdings, Inc.; share changes are against Q4 2025.

Institutions holding XERS in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
MAI Capital Management1,995$11.6K0.00%+1,968+7,288.9%Added
SBI Securities Co., Ltd.1,907$11.1K0.00%00.0%Unchanged
Webster Bank, N. A.1,900$11.0K0.00%−1,100−36.7%Reduced
EverSource Wealth Advisors, LLC1,620$9.39K0.00%−1,198−42.5%Reduced
Fortitude Family Office, LLC1,553$9.01K0.00%00.0%Unchanged
Federation des caisses Desjardins du Quebec1,500$8.70K0.00%+1,500New
Owl Creek Wealth Partners LLC1,435$8.32K0.00%+1,435New
Sound Income Strategies, LLC1,247$7.53K0.00%+98+8.5%Added
Essential Partners LLC1,288$7.47K0.00%00.0%Unchanged
Massmutual Trust Co FSB1,134$6.58K0.00%+456+67.3%Added
The PNC Financial Services Group, Inc.1,053$6.11K0.00%+654+163.9%Added
Sterling Capital Management LLC1,020$5.92K0.00%00.0%Unchanged
True Wealth Design, LLC1,011$5.86K0.00%00.0%Unchanged
Activest Wealth Management1,000$5.80K0.00%00.0%Unchanged
Advisory Services Network, LLC1,000$5.80K0.00%+1,000New
Los Angeles Capital Management LLC791$4.59K0.00%−17,110−95.6%Reduced
Rothschild Investment LLC759$4.40K0.00%+310+69.0%Added
TSFG, LLC708$4.00K0.00%00.0%Unchanged
Aster Capital Management (DIFC) Ltd687$3.77K0.00%+687New
Signaturefd, LLC631$3.66K0.00%−89−12.4%Reduced
Fifth Third Bancorp280$1.62K0.00%+280New
Basecamp Wealth Advisors LLC259$1.50K0.00%+259New
Smartleaf Asset Management LLC225$1.26K0.00%00.0%Unchanged
Spurstone Advisory Services, LLC200$1.16K0.02%00.0%Unchanged
Parkside Financial Bank & Trust155$8990.00%00.0%Unchanged
Larson Financial Group LLC104$6030.00%+104New
GAMMA Investing LLC100$5800.00%+77+334.8%Added
Sunbelt Securities, Inc.81$4700.00%00.0%Unchanged
SJS Investment Consulting Inc.63$3660.00%+44+231.6%Added
Versant Capital Management, Inc49$2840.00%+49New
Steigerwald, Gordon & Koch Inc.37$2150.00%00.0%Unchanged
Atlantic Private Wealth, LLC30$1740.00%00.0%Unchanged
Caitong International Asset Management Co., Ltd25$1450.00%−1,689−98.5%Reduced
IFP Advisors, Inc6$350.00%−134−95.7%Reduced
JPL Wealth Management, LLC6$350.00%+6New
Hughes Financial Services, LLC4$230.00%+4New
Bessemer Group Inc6$00.00%−62−91.2%Reduced
Covestor Ltd20$00.00%−155−88.6%Reduced
Swiss Life Asset Management Ltd33,232––+7,173+27.5%Added
Acadian Asset Management LLC0$00.00%−971,598−100.0%Sold out
Two Sigma Advisers, LP0$00.00%−849,334−100.0%Sold out
Point72 Asset Management, L.P.0$00.00%−608,080−100.0%Sold out
Castleark Management LLC0$00.00%−445,950−100.0%Sold out
Jump Financial, LLC0$00.00%−341,068−100.0%Sold out
Harvest Investment Services, LLC0$00.00%−292,677−100.0%Sold out
Caxton Associates LLP0$00.00%−174,102−100.0%Sold out
Polen Capital Management LLC0$00.00%−133,416−100.0%Sold out
Ambassador Advisors, LLC0$00.00%−106,730−100.0%Sold out
Resolute Capital Asset Partners LLC0$00.00%−100,000−100.0%Sold out
Calamos Advisors LLC0$00.00%−99,117−100.0%Sold out
EAM Investors, LLC0$00.00%−80,154−100.0%Sold out
Deerfield Management Company, L.P. (Series C)0$00.00%−52,230−100.0%Sold out
Axq Capital, LP0$00.00%−46,454−100.0%Sold out
LJI Wealth Management, LLC0$00.00%−42,350−100.0%Sold out
Ausbil Investment Management Ltd0$00.00%−37,000−100.0%Sold out
VARCOV Co.0$00.00%−31,005−100.0%Sold out
9823 Capital, L.P.0$00.00%−24,917−100.0%Sold out
Modern Wealth Management, LLC0$00.00%−17,712−100.0%Sold out
Dynamic Technology Lab Private Ltd0$00.00%−17,200−100.0%Sold out
Numerai GP LLC0$00.00%−17,148−100.0%Sold out
Bailard, Inc.0$00.00%−15,300−100.0%Sold out
O'Shaughnessy Asset Management, LLC0$00.00%−11,423−100.0%Sold out
Jain Global LLC0$00.00%−11,114−100.0%Sold out
Amalgamated Bank0$00.00%−4,824−100.0%Sold out
Kestra Advisory Services, LLC0$00.00%−3,192−100.0%Sold out
Quest Partners LLC0$00.00%−1,204−100.0%Sold out
Hillsdale Investment Management Inc.0$00.00%−1,000−100.0%Sold out
Daiwa Securities Group Inc.0$00.00%−404−100.0%Sold out
Clearstead Advisors, LLC0$00.00%−2−100.0%Sold out
Vanguard Group Inc––––Not filed
Norges Bank––––Not filed
CIBC World Markets Corp––––Not filed
CIBC Private Wealth Group, LLC––––Not filed
Global Retirement Partners, LLC––––Not filed