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Xeris Biopharma Holdings, Inc.

XERS
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001867096

In the last 90 days, Xeris Biopharma Holdings, Inc. insiders filed 0 open-market purchases and 9 sales; 242 institutions reported holding it in 13F filings for Q2 2026, worth $857.8M in total; no superinvestor holds it.

13F holders, Q2 2026

Institutional positions in Xeris Biopharma Holdings, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
242
+7 vs. Q1 2026
Shares held
108.2M
+3.41M (+3.3%) vs. Q1 2026
Total value
$857.1M
+$248.1M (+40.7%) vs. Q1 2026
New holders
34
108 more added
Sold out
27
65 more reduced

4 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting XERS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 242 institutions
Q1 2021: 103 institutionsQ2 2021: 94 institutionsQ3 2021: 71 institutionsQ4 2021: 92 institutionsQ1 2022: 103 institutionsQ2 2022: 103 institutionsQ3 2022: 101 institutionsQ4 2022: 97 institutionsQ1 2023: 92 institutionsQ2 2023: 105 institutionsQ3 2023: 111 institutionsQ4 2023: 120 institutionsQ1 2024: 142 institutionsQ2 2024: 135 institutionsQ3 2024: 144 institutionsQ4 2024: 162 institutionsQ1 2025: 199 institutionsQ2 2025: 201 institutionsQ3 2025: 231 institutionsQ4 2025: 228 institutionsQ1 2026: 239 institutionsQ2 2026: 242 institutions
Value heldQ2 2026: $857.8M
Q1 2021: $149.7MQ2 2021: $114.9MQ3 2021: $42.9MQ4 2021: $122.7MQ1 2022: $130.0MQ2 2022: $91.3MQ3 2022: $89.3MQ4 2022: $71.6MQ1 2023: $80.6MQ2 2023: $147.3MQ3 2023: $102.9MQ4 2023: $145.1MQ1 2024: $140.9MQ2 2024: $137.4MQ3 2024: $183.3MQ4 2024: $223.4MQ1 2025: $481.1MQ2 2025: $423.1MQ3 2025: $796.7MQ4 2025: $792.1MQ1 2026: $611.1MQ2 2026: $857.8M
Institutions holding XERS and their total value by quarter
QuarterHoldersValue
Q2 2026242$857.8M
Q1 2026239$611.1M
Q4 2025228$792.1M
Q3 2025231$796.7M
Q2 2025201$423.1M
Q1 2025199$481.1M
Q4 2024162$223.4M
Q3 2024144$183.3M
Q2 2024135$137.4M
Q1 2024142$140.9M
Q4 2023120$145.1M
Q3 2023111$102.9M
Q2 2023105$147.3M
Q1 202392$80.6M
Q4 202297$71.6M
Q3 2022101$89.3M
Q2 2022103$91.3M
Q1 2022103$130.0M
Q4 202192$122.7M
Q3 202171$42.9M
Q2 202194$114.9M
Q1 2021103$149.7M

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Xeris Biopharma Holdings, Inc.; share changes are against Q1 2026.

Institutions holding XERS in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
BlackRock, Inc.14,525,539$115.0M0.00%+1,579,754+12.2%Added
D. E. Shaw & Co., Inc.7,804,758$61.8M0.04%+15,947+0.2%Added
Vanguard Capital Management LLC7,340,229$58.1M0.00%+359,347+5.1%Added
State Street Corp4,821,566$38.2M0.00%+163,392+3.5%Added
Geode Capital Management, LLC4,718,183$37.4M0.00%+427,554+10.0%Added
Nuveen, LLC4,385,141$34.7M0.01%+1,468,543+50.4%Added
Rosalind Advisors, Inc.2,908,981$23.0M8.65%−322,719−10.0%Reduced
Qube Research & Technologies Ltd2,893,749$22.9M0.03%−1,220,676−29.7%Reduced
Vanguard Portfolio Management LLC2,626,208$20.8M0.00%−39,400−1.5%Reduced
Wellington Management Group LLP2,365,103$18.7M0.00%+193,749+8.9%Added
Morgan Stanley2,337,096$18.5M0.00%−235,558−9.2%Reduced
Legal & General Group Plc2,012,792$15.9M0.00%+104,503+5.5%Added
Armistice Capital, LLC1,958,702$15.5M0.43%+48,864+2.6%Added
Two Sigma Investments, LP1,885,503$14.9M0.01%−38,699−2.0%Reduced
Parkman Healthcare Partners LLC1,807,621$14.3M1.47%+86,357+5.0%Added
Algert Global LLC1,742,942$13.8M0.16%+585,984+50.6%Added
Northern Trust Corp1,597,749$12.7M0.00%+153,132+10.6%Added
Goldman Sachs Group Inc1,594,072$12.6M0.00%−19,578−1.2%Reduced
AQR Capital Management LLC1,540,985$12.2M0.00%+146,609+10.5%Added
Charles Schwab Investment Management Inc1,492,367$11.8M0.00%+132,710+9.8%Added
Federated Hermes, Inc.1,434,433$11.4M0.02%+577,620+67.4%Added
Bank of America Corp1,397,050$11.1M0.00%+522,653+59.8%Added
UBS Group AG1,300,913$10.3M0.00%−345,465−21.0%Reduced
Ishara Investments LP1,230,000$9.74M7.16%+205,000+20.0%Added
Vanguard Fiduciary Trust Co1,224,398$9.70M0.00%+90,496+8.0%Added
Kennedy Capital Management, Inc.1,209,068$9.58M0.17%−31,624−2.5%Reduced
Dimensional Fund Advisors LP1,073,639$8.50M0.00%+1,073,639New
Knott David M Jr1,060,000$8.40M4.44%00.0%Unchanged
JPMorgan Chase & Co1,058,067$8.19M0.00%+445,588+72.8%Added
Arrowstreet Capital, Limited Partnership972,880$7.71M0.00%+839,120+627.3%Added
Granahan Investment Management Inc898,753$7.12M0.25%−23,101−2.5%Reduced
Norges Bank797,200$6.31M0.00%+797,200New
Essex Investment Management Co LLC715,608$5.67M0.74%−32,161−4.3%Reduced
UBS Asset Management Americas Inc687,632$5.45M0.00%+19,558+2.9%Added
Voya Investment Management LLC685,570$5.43M0.00%+60,260+9.6%Added
Citadel Advisors LLC664,564$5.26M0.00%−17,070−2.5%Reduced
FMR LLC644,057$5.10M0.00%+130,981+25.5%Added
Walleye Capital LLC611,296$4.84M0.02%+611,296New
Deutsche Bank AG529,443$4.19M0.00%−93,569−15.0%Reduced
Bank of New York Mellon Corp488,441$3.87M0.00%+62,156+14.6%Added
First Trust Advisors LP484,978$3.84M0.00%+484,978New
IHT Wealth Management, LLC481,871$3.82M0.08%+105,395+28.0%Added
Perceptive Advisors LLC467,013$3.70M0.06%+467,013New
Royce & Associates LP461,153$3.65M0.03%+205,066+80.1%Added
Man Group plc455,380$3.61M0.01%+178,958+64.7%Added
Russell Investments Group, Ltd.440,731$3.49M0.00%+56,536+14.7%Added
BNP Paribas Arbitrage, SA430,488$3.41M0.00%+167,701+63.8%Added
State of Wisconsin Investment Board427,513$3.39M0.01%+118,967+38.6%Added
Jupiter Topco LLC414,959$3.29M0.00%+414,959New
Y-Intercept (Hong Kong) Ltd411,346$3.26M0.06%+249,553+154.2%Added
Squarepoint Ops LLC365,731$2.90M0.01%−248,819−40.5%Reduced
HRT Financial LP365,659$2.90M0.01%+194,557+113.7%Added
SEI Investments Co339,509$2.69M0.00%−239,701−41.4%Reduced
Trexquant Investment LP339,113$2.69M0.02%−494,104−59.3%Reduced
Swiss National Bank337,500$2.67M0.00%+9,200+2.8%Added
Schonfeld Strategic Advisors LLC318,177$2.52M0.01%+21,746+7.3%Added
Rice Hall James & Associates, LLC300,791$2.38M0.12%+49,725+19.8%Added
Jefferies Financial Group Inc.293,670$2.33M0.02%+205,870+234.5%Added
CenterBook Partners LP280,565$2.22M0.11%−968,056−77.5%Reduced
Price T Rowe Associates Inc266,877$2.11M0.00%+57,843+27.7%Added
Healthcare of Ontario Pension Plan Trust Fund263,537$2.09M0.00%−200,547−43.2%Reduced
Cliffwater LLC263,158$2.08M0.52%+263,158New
Apella Capital, LLC215,897$1.93M0.03%−20,000−8.5%Reduced
Legato Capital Management LLC241,341$1.91M0.16%+7,197+3.1%Added
Panagora Asset Management Inc227,579$1.80M0.01%+122,835+117.3%Added
Principal Financial Group Inc227,418$1.80M0.00%+18,911+9.1%Added
Group One Trading, L.P.226,607$1.79M0.05%+8,462+3.9%Added
Canada Pension Plan Investment Board219,200$1.74M0.00%−155,600−41.5%Reduced
Rhumbline Advisers214,205$1.70M0.00%+23,138+12.1%Added
Commonwealth Equity Services, LLC205,855$1.63M0.00%+2,739+1.3%Added
Voleon Capital Management LP204,732$1.62M0.03%+158,224+340.2%Added
Raymond James Financial Inc202,911$1.61M0.00%−5,362−2.6%Reduced
Aquatic Capital Management LLC199,983$1.58M0.05%+199,983New
Caption Management, LLC197,863$1.57M0.06%−7,137−3.5%Reduced
California State Teachers Retirement System186,800$1.48M0.00%+6,461+3.6%Added
CI Private Wealth, LLC184,126$1.46M0.00%+184,126New
Virtus Investment Advisers, Inc.171,264$1.36M0.32%+133,234+350.3%Added
Barclays PLC166,566$1.32M0.00%+28,013+20.2%Added
Wells Fargo & Company157,487$1.25M0.00%+99,180+170.1%Added
Creative Planning154,059$1.22M0.00%+20,774+15.6%Added
Quarry LP150,057$1.19M0.19%+25,057+20.0%Added
Globeflex Capital L P145,917$1.16M0.15%+22,733+18.5%Added
Ameriprise Financial Inc143,285$1.13M0.00%+1,137+0.8%Added
Susquehanna International Group, LLP139,918$1.11M0.00%−146,153−51.1%Reduced
Citigroup Inc134,298$1.06M0.00%+46,973+53.8%Added
Vanguard Asset Management, Ltd133,417$1.06M0.00%+29,862+28.8%Added
Diadema Partners LP132,746$1.05M0.37%00.0%Unchanged
Millennium Management LLC131,664$1.04M0.00%−2,134,310−94.2%Reduced
LPL Financial LLC128,941$1.02M0.00%+35,080+37.4%Added
Connor, Clark & Lunn Investment Management Ltd.127,107$1.01M0.00%−280,518−68.8%Reduced
Gotham Asset Management, LLC123,914$981.4K0.00%+80,657+186.5%Added
Quantbot Technologies LP111,102$879.9K0.03%+83,038+295.9%Added
Invesco Ltd.109,875$870.2K0.00%+6,581+6.4%Added
Alliancebernstein L.P.145,336$842.9K0.00%00.0%Unchanged
Palo Alto Investors LP104,410$826.9K0.11%00.0%Unchanged
MetLife Investment Management100,167$793.3K0.00%+23,404+30.5%Added
Ieq Capital, LLC98,429$779.6K0.00%+16,799+20.6%Added
American Century Companies Inc93,345$739.3K0.00%+93,345New
Franklin Resources Inc88,885$704.0K0.00%+8,668+10.8%Added
Gsa Capital Partners LLP82,830$656.0K0.04%−18,608−18.3%Reduced