Xeris Biopharma Holdings, Inc.
XERS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001867096
In the last 90 days, Xeris Biopharma Holdings, Inc. insiders filed 0 open-market purchases and 9 sales; 242 institutions reported holding it in 13F filings for Q2 2026, worth $857.1M in total; no superinvestor holds it.
13F holders, Q1 2025
Institutional positions in Xeris Biopharma Holdings, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 199
- +39 vs. Q4 2024
- Shares held
- 87.6M
- +23.9M (+37.6%) vs. Q4 2024
- Total value
- $480.9M
- +$265.1M (+122.9%) vs. Q4 2024
- New holders
- 57
- 72 more added
- Sold out
- 18
- 39 more reduced
2 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting XERS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 242 | $857.1M |
| Q1 2026 | 239 | $610.3M |
| Q4 2025 | 227 | $792.0M |
| Q3 2025 | 231 | $789.3M |
| Q2 2025 | 201 | $422.9M |
| Q1 2025 | 199 | $480.9M |
| Q4 2024 | 162 | $222.2M |
| Q3 2024 | 144 | $182.2M |
| Q2 2024 | 135 | $136.6M |
| Q1 2024 | 142 | $133.7M |
| Q4 2023 | 120 | $140.8M |
| Q3 2023 | 111 | $102.3M |
| Q2 2023 | 105 | $146.7M |
| Q1 2023 | 92 | $80.6M |
| Q4 2022 | 97 | $71.6M |
| Q3 2022 | 101 | $89.3M |
| Q2 2022 | 103 | $91.3M |
| Q1 2022 | 103 | $129.2M |
| Q4 2021 | 92 | $120.2M |
| Q3 2021 | 71 | $42.9M |
| Q2 2021 | 94 | $114.9M |
| Q1 2021 | 103 | $149.7M |
Institutions, Q1 2025
Shares, value and share of portfolio for each institution holding Xeris Biopharma Holdings, Inc.; share changes are against Q4 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| BlackRock, Inc. | 10,794,601 | $59.3M | 0.00% | −26,527−0.2% | Reduced |
| Vanguard Group Inc | 8,109,644 | $44.5M | 0.00% | +210,581+2.7% | Added |
| Morgan Stanley | 4,288,281 | $23.5M | 0.00% | +1,410,765+49.0% | Added |
| Geode Capital Management, LLC | 3,405,826 | $18.7M | 0.00% | +54,400+1.6% | Added |
| State Street Corp | 3,325,255 | $18.3M | 0.00% | −16,619−0.5% | Reduced |
| D. E. Shaw & Co., Inc. | 3,052,372 | $16.8M | 0.02% | +1,688,920+123.9% | Added |
| Goldman Sachs Group Inc | 2,790,014 | $15.3M | 0.00% | +1,199,435+75.4% | Added |
| Rosalind Advisors, Inc. | 2,495,986 | $13.7M | 6.68% | −609,009−19.6% | Reduced |
| Millennium Management LLC | 2,317,972 | $12.7M | 0.01% | +369,420+19.0% | Added |
| Nuveen, LLC | 2,229,507 | $12.2M | 0.00% | +2,229,507 | New |
| Renaissance Technologies LLC | 2,162,640 | $11.9M | 0.02% | +63,800+3.0% | Added |
| JPMorgan Chase & Co | 2,114,709 | $11.6M | 0.00% | +1,071,268+102.7% | Added |
| Qube Research & Technologies Ltd | 1,844,583 | $10.1M | 0.02% | +1,384,975+301.3% | Added |
| Parkman Healthcare Partners LLC | 1,780,454 | $9.77M | 1.16% | +1,201,943+207.8% | Added |
| Bank of America Corp | 1,709,409 | $9.38M | 0.00% | +717,752+72.4% | Added |
| Legal & General Group Plc | 1,411,614 | $7.75M | 0.00% | +1,181,147+512.5% | Added |
| Driehaus Capital Management LLC | 1,411,540 | $7.75M | 0.07% | +817,525+137.6% | Added |
| Voloridge Investment Management, LLC | 1,351,114 | $7.42M | 0.03% | +1,351,114 | New |
| Citadel Advisors LLC | 1,347,859 | $7.40M | 0.01% | +514,531+61.7% | Added |
| Northern Trust Corp | 1,201,200 | $6.59M | 0.00% | +4,819+0.4% | Added |
| Knott David M Jr | 1,110,000 | $6.09M | 2.88% | +110,000+11.0% | Added |
| Prudential Financial Inc | 1,098,845 | $6.03M | 0.01% | +1,061,900+2,874.3% | Added |
| Invesco Ltd. | 1,026,838 | $5.64M | 0.00% | +957,822+1,387.8% | Added |
| AQR Capital Management LLC | 946,766 | $5.20M | 0.01% | +111,826+13.4% | Added |
| EAM Investors, LLC | 934,646 | $5.13M | 0.89% | +712,269+320.3% | Added |
| Two Sigma Advisers, LP | 925,615 | $5.08M | 0.01% | +911,874+6,636.2% | Added |
| Two Sigma Investments, LP | 890,337 | $4.89M | 0.01% | +890,337 | New |
| UBS Group AG | 863,776 | $4.74M | 0.00% | −870,715−50.2% | Reduced |
| Norges Bank | 823,800 | $4.52M | 0.00% | +823,800 | New |
| Jane Street Group, LLC | 820,222 | $4.50M | 0.01% | +513,977+167.8% | Added |
| Cubist Systematic Strategies, LLC | 811,607 | $4.46M | 0.06% | +811,607 | New |
| Deutsche Bank AG | 756,407 | $4.15M | 0.00% | +628,807+492.8% | Added |
| Kennedy Capital Management, Inc. | 735,087 | $4.04M | 0.10% | +68,992+10.4% | Added |
| Essex Investment Management Co LLC | 730,444 | $4.01M | 0.84% | +255,489+53.8% | Added |
| Walleye Capital LLC | 691,719 | $3.80M | 0.04% | +691,719 | New |
| Federated Hermes, Inc. | 687,783 | $3.78M | 0.01% | +685,906+36,542.7% | Added |
| Susquehanna International Group, LLP | 637,782 | $3.50M | 0.01% | +530,438+494.1% | Added |
| Schonfeld Strategic Advisors LLC | 600,167 | $3.29M | 0.02% | +497,167+482.7% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 589,471 | $3.24M | 0.01% | +418,139+244.1% | Added |
| CenterBook Partners LP | 472,075 | $2.59M | 0.17% | −218,002−31.6% | Reduced |
| Redmile Group, LLC | 451,099 | $2.48M | 0.23% | 00.0% | Unchanged |
| Charles Schwab Investment Management Inc | 423,775 | $2.33M | 0.00% | +20,903+5.2% | Added |
| Jump Financial, LLC | 423,523 | $2.33M | 0.03% | +394,739+1,371.4% | Added |
| Wellington Management Group LLP | 392,099 | $2.15M | 0.00% | −73,013−15.7% | Reduced |
| Bank of New York Mellon Corp | 360,324 | $1.98M | 0.00% | +37,949+11.8% | Added |
| BNP Paribas Arbitrage, SA | 344,888 | $1.89M | 0.00% | +244,876+244.8% | Added |
| FMR LLC | 311,472 | $1.71M | 0.00% | +263,698+552.0% | Added |
| Barclays PLC | 280,635 | $1.54M | 0.00% | −67,007−19.3% | Reduced |
| Voss Capital, LLC | 275,000 | $1.51M | 0.12% | +275,000 | New |
| IHT Wealth Management, LLC | 262,805 | $1.44M | 0.05% | −7,355−2.7% | Reduced |
| Jacobs Levy Equity Management, Inc | 255,560 | $1.40M | 0.01% | +255,560 | New |
| Healthcare of Ontario Pension Plan Trust Fund | 252,000 | $1.38M | 0.00% | +252,000 | New |
| PDT Partners, LLC | 239,600 | $1.32M | 0.09% | +239,600 | New |
| Tudor Investment Corp Et Al | 225,186 | $1.24M | 0.01% | −80,000−26.2% | Reduced |
| Legato Capital Management LLC | 217,318 | $1.19M | 0.16% | +75,154+52.9% | Added |
| XTX Topco Ltd | 216,228 | $1.19M | 0.06% | +216,228 | New |
| Royal Bank of Canada | 213,084 | $1.17M | 0.00% | +198,984+1,411.2% | Added |
| Commonwealth Equity Services, LLC | 197,443 | $1.08M | 0.00% | +10,000+5.3% | Added |
| Rhumbline Advisers | 192,281 | $1.06M | 0.00% | +11,317+6.3% | Added |
| Brevan Howard Capital Management LP | 192,276 | $1.06M | 0.03% | +192,276 | New |
| Raymond James Financial Inc | 180,316 | $989.9K | 0.00% | +167,166+1,271.2% | Added |
| Price T Rowe Associates Inc | 176,393 | $969.0K | 0.00% | +5,911+3.5% | Added |
| Diversified Trust Co | 175,739 | $964.8K | 0.02% | 00.0% | Unchanged |
| Man Group plc | 175,247 | $962.1K | 0.00% | +175,247 | New |
| Thompson Siegel & Walmsley LLC | 172,784 | $949.0K | 0.02% | +20,000+13.1% | Added |
| Ameriprise Financial Inc | 168,102 | $922.9K | 0.00% | −41,821−19.9% | Reduced |
| Semanteon Capital Management, LP | 156,191 | $857.5K | 0.47% | +156,191 | New |
| Ieq Capital, LLC | 155,184 | $852.0K | 0.01% | +87,469+129.2% | Added |
| Panagora Asset Management Inc | 145,526 | $798.9K | 0.00% | +145,526 | New |
| Alliancebernstein L.P. | 144,830 | $795.1K | 0.00% | +13,260+10.1% | Added |
| Mackenzie Financial Corp | 142,104 | $780.2K | 0.00% | +12,152+9.4% | Added |
| Gsa Capital Partners LLP | 138,735 | $762.0K | 0.07% | +88,892+178.3% | Added |
| Fred Alger Management, LLC | 134,016 | $735.7K | 0.00% | +134,016 | New |
| Graham Capital Management, L.P. | 133,668 | $733.8K | 0.02% | +63,006+89.2% | Added |
| Russell Investments Group, Ltd. | 131,687 | $723.0K | 0.00% | +113,713+632.7% | Added |
| Globeflex Capital L P | 125,210 | $687.4K | 0.06% | 00.0% | Unchanged |
| Occudo Quantitative Strategies LP | 120,424 | $672.0K | 0.09% | +68,687+132.8% | Added |
| Roundview Capital LLC | 120,000 | $658.8K | 0.05% | 00.0% | Unchanged |
| Citigroup Inc | 118,208 | $649.0K | 0.00% | −14,238−10.8% | Reduced |
| Brown Advisory Inc | 114,698 | $629.7K | 0.00% | −75,557−39.7% | Reduced |
| Principal Financial Group Inc | 113,746 | $624.5K | 0.00% | +529+0.5% | Added |
| Franklin Resources Inc | 107,936 | $592.6K | 0.00% | +88,375+451.8% | Added |
| Creative Planning | 106,732 | $586.0K | 0.00% | +15,465+16.9% | Added |
| Stonepine Capital Management, LLC | 102,265 | $561.4K | 0.65% | −80,052−43.9% | Reduced |
| Alpine Global Management, LLC | 100,000 | $549.0K | 0.15% | −60,000−37.5% | Reduced |
| SEI Investments Co | 97,491 | $535.2K | 0.00% | +97,491 | New |
| Point72 Asset Management, L.P. | 88,373 | $485.2K | 0.00% | +88,373 | New |
| Options Solutions, LLC | 85,111 | $467.3K | 0.22% | +85,111 | New |
| Mirae Asset Global ETFs Holdings Ltd. | 83,982 | $461.1K | 0.00% | +3,594+4.5% | Added |
| MetLife Investment Management | 81,769 | $448.9K | 0.00% | −5,663−6.5% | Reduced |
| HRT Financial LP | 81,112 | $445.0K | 0.00% | +60,440+292.4% | Added |
| OrbiMed Advisors LLC | 80,420 | $441.5K | 0.01% | 00.0% | Unchanged |
| EntryPoint Capital, LLC | 75,706 | $415.6K | 0.19% | +22,946+43.5% | Added |
| Sigma Planning Corp | 73,950 | $406.0K | 0.01% | −3,000−3.9% | Reduced |
| Quarry LP | 70,751 | $388.4K | 0.10% | +70,751 | New |
| SG Americas Securities, LLC | 70,499 | $387.0K | 0.00% | −24,172−25.5% | Reduced |
| Wells Fargo & Company | 69,881 | $383.6K | 0.00% | −9,155−11.6% | Reduced |
| Corebridge Financial, Inc. | 68,698 | $377.2K | 0.00% | −1,018−1.5% | Reduced |
| CWM, LLC | 66,972 | $368.0K | 0.00% | +29,614+79.3% | Added |
| GPS Wealth Strategies Group, LLC | 66,925 | $367.4K | 0.05% | 00.0% | Unchanged |