Xeris Biopharma Holdings, Inc.

XERS

Exchange: Nasdaq
Industry: Pharmaceutical Preparations
SEC CIK: 0001867096

SEC filings (opens in a new tab)

In the last 90 days, Xeris Biopharma Holdings, Inc. insiders filed 0 open-market purchases and 10 sales; 242 institutions reported holding it in 13F filings for Q2 2026, worth $857.1M in total; no superinvestor holds it.

Q4 2025 vs. Q3 2025

How the institutions holding Xeris Biopharma Holdings, Inc. changed between Q3 2025 and Q4 2025.

All holders in Q4 2025 All holders in Q3 2025

13F holders of XERS: Q3 2025 compared with Q4 2025
Measure	Q3 2025	Of which not filed for Q4 2025	Q4 2025	Change
Holders	231	1	227	−3
Shares	97.0M	16.4K	100.9M	+3.95M (+4.1%)
Value	$789.3M	$133.2K	$792.0M	+$2.83M (+0.4%)

1 institution that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so the changes leave them out.

New holders (35)

Institutions that held Xeris Biopharma Holdings, Inc. at the end of Q4 2025 but not at the end of Q3 2025.

Institutions new to XERS in Q4 2025
Institution	Shares	Value	% of portfolio
Norges Bank	800,700	$6.29M	0.00%
Ishara Investments LP	800,000	$6.28M	7.31%
Point72 Asset Management, L.P.	608,080	$4.77M	0.01%
Castleark Management LLC	445,950	$3.50M	0.10%
Voss Capital, LLC	371,709	$2.92M	0.16%
Arrowstreet Capital, Limited Partnership	214,786	$1.69M	0.00%
Ambassador Advisors, LLC	106,730	$837.8K	0.12%
Resolute Capital Asset Partners LLC	100,000	$785.0K	0.38%
Jefferies Financial Group Inc.	87,800	$689.2K	0.01%
Western Wealth Management, LLC	75,675	$594.0K	0.03%
Teachers Retirement System of the State of Kentucky	72,907	$572.0K	0.00%
Integrated Quantitative Investments LLC	66,170	$519.4K	0.11%
Penn Capital Management Co Inc	48,064	$377.3K	0.03%
Man Group plc	47,775	$375.0K	0.00%
AlphaCentric Advisors LLC	43,392	$340.6K	0.34%
Ausbil Investment Management Ltd	37,000	$290.4K	0.17%
VARCOV Co.	31,005	$243.4K	0.10%
Fox Run Management, L.L.C.	26,174	$205.5K	0.03%
Swiss Life Asset Management Ltd	26,059	$204.6K	0.00%
9823 Capital, L.P.	24,917	$195.6K	0.13%
Dynamic Technology Lab Private Ltd	17,200	$135.0K	0.03%
Bailard, Inc.	15,300	$120.1K	0.00%
Skopos Labs, Inc.	12,195	$90.6K	0.00%
Jain Global LLC	11,114	$87.2K	0.00%
CIBC World Markets Corp	10,158	$79.7K	0.00%
Kingsview Wealth Management, LLC	10,000	$78.5K	0.00%
Kemnay Advisory Services Inc.	8,480	$66.6K	0.01%
Kestra Advisory Services, LLC	3,192	$25.1K	0.00%
BNP PARIBAS ASSET MANAGEMENT Holding S.A.	2,353	$18.0K	0.00%
Sound Income Strategies, LLC	1,149	$8.64K	0.00%
Rockefeller Capital Management L.P.	594	$4.66K	0.00%
Smartleaf Asset Management LLC	225	$1.65K	0.00%
Atlantic Private Wealth, LLC	30	$236	0.00%
MAI Capital Management	27	$212	0.00%
SJS Investment Consulting Inc.	19	$150	0.00%

Sold out (38)

Institutions that held Xeris Biopharma Holdings, Inc. at the end of Q3 2025 and filed for Q4 2025 without it.

Institutions that sold out of XERS in Q4 2025
Institution	Shares, Q3 2025	Value, Q3 2025
Walleye Capital LLC	623,962	$5.08M
Redmile Group, LLC	451,099	$3.67M
Divisadero Street Capital Management, LP	406,334	$3.31M
Mackenzie Financial Corp	152,161	$1.24M
CWM Advisors, LLC	128,494	$1.05M
Roundview Capital LLC	120,000	$976.8K
Fred Alger Management, LLC	108,936	$886.7K
ExodusPoint Capital Management, LP	86,920	$707.5K
Aquatic Capital Management LLC	83,000	$675.6K
OrbiMed Advisors LLC	80,420	$654.6K
Bayesian Capital Management, LP	70,800	$576.3K
GPS Wealth Strategies Group, LLC	65,089	$529.8K
Occudo Quantitative Strategies LP	47,674	$388.1K
Simplex Trading, LLC	45,931	$373.0K
Semanteon Capital Management, LP	32,925	$268.0K
Baader Bank INC	28,312	$230.1K
Skandinaviska Enskilda Banken AB (publ)	25,000	$203.5K
Omers Administration Corp	24,600	$200.2K
Petrus Trust Company, LTA	24,351	$198.2K
Sunpointe, LLC	21,000	$170.9K
Verdence Capital Advisors LLC	17,549	$163.4K
Toroso Investments, LLC	19,485	$158.6K
Quadrature Capital Ltd	17,289	$140.8K
Capstone Investment Advisors, LLC	17,130	$139.4K
Susquehanna Fundamental Investments, LLC	17,087	$139.1K
JustInvest LLC	15,561	$126.7K
Prelude Capital Management, LLC	15,500	$126.2K
Atom Investors LP	14,968	$121.8K
Avenue 1 Advisors, LLC	14,163	$115.3K
R Squared Ltd	12,709	$103.5K
Verition Fund Management LLC	12,229	$99.5K
Mercer Global Advisors Inc	10,466	$85.2K
Mariner, LLC	10,404	$84.7K
Advisory Services Network, LLC	1,000	$8.14K
Larson Financial Group LLC	400	$3.26K
Wealthspire Advisors, LLC	354	$2.88K
Optiver Holding B.V.	336	$2.73K
Comerica Bank	308	$2.51K

Not filed for Q4 2025 yet (1)

Institutions that held Xeris Biopharma Holdings, Inc. at the end of Q3 2025 and haven't filed a 13F for Q4 2025. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding XERS in Q3 2025 that haven't filed for Q4 2025
Institution	Shares, Q3 2025	Value, Q3 2025
CIBC Bancorp USA Inc.	16,367	$133.2K