Wave Life Sciences, Inc.
WVE- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001631574
In the last 90 days, Wave Life Sciences, Inc. insiders filed 0 open-market purchases and 4 sales; 239 institutions reported holding it in 13F filings for Q2 2026, worth $1.06B in total; superinvestors Maverick Capital and Duquesne Family Office hold it.
13F holders, Q4 2025
Institutional positions in Wave Life Sciences, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 219
- +35 vs. Q3 2025
- Shares held
- 182.7M
- +39.1M (+27.3%) vs. Q3 2025
- Total value
- $3.11B
- +$2.06B (+195.7%) vs. Q3 2025
- New holders
- 73
- 79 more added
- Sold out
- 38
- 47 more reduced
5 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting WVE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 239 | $1.06B |
| Q1 2026 | 232 | $1.25B |
| Q4 2025 | 219 | $3.11B |
| Q3 2025 | 189 | $1.05B |
| Q2 2025 | 177 | $903.1M |
| Q1 2025 | 197 | $1.06B |
| Q4 2024 | 184 | $1.59B |
| Q3 2024 | 162 | $986.1M |
| Q2 2024 | 144 | $474.4M |
| Q1 2024 | 132 | $572.3M |
| Q4 2023 | 115 | $468.0M |
| Q3 2023 | 85 | $417.4M |
| Q2 2023 | 81 | $262.7M |
| Q1 2023 | 73 | $303.5M |
| Q4 2022 | 75 | $476.9M |
| Q3 2022 | 61 | $242.8M |
| Q2 2022 | 60 | $220.3M |
| Q1 2022 | 82 | $95.4M |
| Q4 2021 | 90 | $148.5M |
| Q3 2021 | 88 | $183.5M |
| Q2 2021 | 87 | $246.7M |
| Q1 2021 | 102 | $214.8M |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Wave Life Sciences, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Sig Brokerage, LP | 48,384 | $822.5K | 0.28% | +30,413+169.2% | Added |
| Russell Investments Group, Ltd. | 49,903 | $848.4K | 0.00% | +39,975+402.6% | Added |
| Janus Henderson Group PLC | 51,700 | $877.6K | 0.00% | 00.0% | Unchanged |
| J. Goldman & Co LP | 53,762 | $914.0K | 0.04% | +53,762 | New |
| SEI Investments Co | 54,457 | $925.8K | 0.00% | −17,798−24.6% | Reduced |
| Handelsbanken Fonder AB | 54,700 | $930.0K | 0.00% | +3,900+7.7% | Added |
| Cinctive Capital Management LP | 61,831 | $1.05M | 0.06% | −48,706−44.1% | Reduced |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 62,729 | $1.07M | 0.00% | +10,683+20.5% | Added |
| MetLife Investment Management | 64,763 | $1.10M | 0.01% | +5,557+9.4% | Added |
| SG Americas Securities, LLC | 67,031 | $1.14M | 0.00% | +67,031 | New |
| Group One Trading, L.P. | 67,969 | $1.16M | 0.03% | +24,590+56.7% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 69,078 | $1.17M | 0.00% | +69,078 | New |
| a16z Perennial Management, L.P. | 77,619 | $1.32M | 0.10% | 00.0% | Unchanged |
| BNP Paribas Arbitrage, SA | 82,022 | $1.39M | 0.00% | +58,400+247.2% | Added |
| Ikarian Capital, LLC | 85,285 | $1.45M | 0.19% | −10,670−11.1% | Reduced |
| State of Wisconsin Investment Board | 87,141 | $1.48M | 0.00% | +28,010+47.4% | Added |
| Knott David M Jr | 90,000 | $1.53M | 0.71% | 00.0% | Unchanged |
| Prescott Group Capital Management, L.L.C. | 90,000 | $1.53M | 0.14% | +90,000 | New |
| Prelude Capital Management, LLC | 93,202 | $1.58M | 0.12% | +93,202 | New |
| Legal & General Group Plc | 93,985 | $1.60M | 0.00% | −7,931−7.8% | Reduced |
| Dark Forest Capital Management LP | 95,068 | $1.62M | 0.07% | −167,509−63.8% | Reduced |
| Deutsche Bank AG | 95,706 | $1.63M | 0.00% | +1,441+1.5% | Added |
| LMR Partners LLP | 100,000 | $1.70M | 0.02% | +100,000 | New |
| Seven Grand Managers, LLC | 100,000 | $1.70M | 0.13% | +100,000 | New |
| Itau Unibanco Holding S.A. | 102,000 | $1.75M | 0.04% | +102,000 | New |
| James J. Burns & Company, LLC | 105,802 | $1.80M | 0.25% | 00.0% | Unchanged |
| California State Teachers Retirement System | 107,680 | $1.83M | 0.00% | +9,185+9.3% | Added |
| Jane Street Group, LLC | 110,924 | $1.89M | 0.00% | −508,717−82.1% | Reduced |
| Raymond James Financial Inc | 111,170 | $1.89M | 0.00% | +95,483+608.7% | Added |
| Alliancebernstein L.P. | 112,030 | $1.90M | 0.00% | +19,200+20.7% | Added |
| Voya Investment Management LLC | 112,875 | $1.92M | 0.00% | −145,136−56.3% | Reduced |
| Algert Global LLC | 122,470 | $2.08M | 0.03% | +122,470 | New |
| Mirae Asset Global ETFs Holdings Ltd. | 134,558 | $2.29M | 0.00% | +282+0.2% | Added |
| Rhumbline Advisers | 141,895 | $2.41M | 0.00% | −17,278−10.9% | Reduced |
| Burkehill Global Management, LP | 150,000 | $2.55M | 0.17% | +150,000 | New |
| Sofinnova Investments, Inc. | 158,182 | $2.69M | 0.12% | −12,761−7.5% | Reduced |
| UBS Asset Management Americas Inc | 164,985 | $2.80M | 0.00% | +164,985 | New |
| Principal Financial Group Inc | 170,170 | $2.89M | 0.00% | +170,170 | New |
| Duquesne Family Office LLCSuperinvestorDuquesne Family Office | 173,000 | $2.94M | 0.07% | +173,000 | New |
| Squadron Capital Management LLC | 175,000 | $2.98M | 1.33% | +175,000 | New |
| Invesco Ltd. | 179,932 | $3.06M | 0.00% | +38,806+27.5% | Added |
| Bank of America Corp | 182,855 | $3.11M | 0.00% | −482,295−72.5% | Reduced |
| Manufacturers Life Insurance Company, The | 182,728 | $3.13M | 0.00% | +57,369+45.8% | Added |
| Privium Fund Management B.V. | 193,010 | $3.28M | 0.60% | +23,010+13.5% | Added |
| Wells Fargo & Company | 200,890 | $3.42M | 0.00% | +127,079+172.2% | Added |
| AQR Capital Management LLC | 202,721 | $3.45M | 0.00% | +192,023+1,794.9% | Added |
| Nomura Asset Management International Inc. | 203,744 | $3.46M | 0.01% | +203,744 | New |
| Swiss National Bank | 219,700 | $3.73M | 0.00% | +8,700+4.1% | Added |
| Susquehanna Portfolio Strategies, LLC | 230,512 | $3.92M | 0.06% | −74,862−24.5% | Reduced |
| Platinum Investment Management Ltd | 230,687 | $3.92M | 0.91% | −37,107−13.9% | Reduced |
| Boothbay Fund Management, LLC | 234,799 | $3.99M | 0.10% | +113,637+93.8% | Added |
| Renaissance Technologies LLC | 236,420 | $4.02M | 0.01% | +236,420 | New |
| EAM Investors, LLC | 248,815 | $4.23M | 0.47% | +248,815 | New |
| TD Asset Management Inc | 252,160 | $4.29M | 0.00% | +109,752+77.1% | Added |
| D. E. Shaw & Co., Inc. | 266,132 | $4.52M | 0.00% | +266,132 | New |
| UBS Group AG | 268,723 | $4.57M | 0.00% | −436,885−61.9% | Reduced |
| Moody Aldrich Partners LLC | 274,425 | $4.67M | 0.87% | −76,123−21.7% | Reduced |
| Barclays PLC | 276,781 | $4.71M | 0.00% | +3,907+1.4% | Added |
| HRT Financial LP | 299,718 | $5.09M | 0.02% | +299,718 | New |
| Newtyn Management, LLC | 300,000 | $5.10M | 0.54% | 00.0% | Unchanged |
| Jump Financial, LLC | 313,509 | $5.33M | 0.07% | +313,509 | New |
| Bank of New York Mellon Corp | 321,445 | $5.46M | 0.00% | +23,589+7.9% | Added |
| Jain Global LLC | 328,145 | $5.58M | 0.05% | +328,145 | New |
| Nuveen, LLC | 332,735 | $5.66M | 0.00% | +83,266+33.4% | Added |
| Jacobs Levy Equity Management, Inc | 338,546 | $5.76M | 0.02% | +338,546 | New |
| Baker Bros. Advisors LP | 344,063 | $5.85M | 0.03% | 00.0% | Unchanged |
| Woodline Partners LP | 350,531 | $5.96M | 0.02% | +350,531 | New |
| Boone Capital Management LLC | 352,144 | $5.99M | 1.88% | +352,144 | New |
| Wellington Management Group LLP | 365,235 | $6.21M | 0.00% | −64,384−15.0% | Reduced |
| Walleye Capital LLC | 378,823 | $6.44M | 0.04% | −351,816−48.2% | Reduced |
| Susquehanna International Group, LLP | 378,987 | $6.44M | 0.01% | +182,707+93.1% | Added |
| Trexquant Investment LP | 391,111 | $6.65M | 0.06% | +391,111 | New |
| F/M Investments LLC | 395,894 | $6.73M | 0.26% | +77,807+24.5% | Added |
| Ameriprise Financial Inc | 398,416 | $6.77M | 0.00% | +290,551+269.4% | Added |
| Sphera Funds Management Ltd. | 408,166 | $6.94M | 1.45% | +358,166+716.3% | Added |
| Morgan Stanley | 409,663 | $6.96M | 0.00% | −97,627−19.2% | Reduced |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 411,494 | $7.00M | 0.01% | +42,789+11.6% | Added |
| Exome Asset Management LLC | 421,488 | $7.17M | 3.54% | +421,488 | New |
| Elmind Capital, LP | 447,846 | $7.61M | 2.25% | +447,846 | New |
| Kennedy Capital Management, Inc. | 492,437 | $8.37M | 0.18% | −48,000−8.9% | Reduced |
| Eventide Asset Management, LLC | 500,000 | $8.50M | 0.13% | +500,000 | New |
| Millennium Management LLC | 584,633 | $9.94M | 0.01% | +193,884+49.6% | Added |
| Tang Capital Management LLC | 600,000 | $10.2M | 0.50% | +600,000 | New |
| Voloridge Investment Management, LLC | 722,237 | $12.3M | 0.04% | +722,237 | New |
| Two Sigma Investments, LP | 749,448 | $12.7M | 0.02% | +186,444+33.1% | Added |
| Citadel Advisors LLC | 789,964 | $13.4M | 0.01% | +789,964 | New |
| Pictet Asset Management Holding SA | 805,901 | $13.8M | 0.01% | +790,175+5,024.6% | Added |
| Squarepoint Ops LLC | 883,586 | $15.0M | 0.03% | +609,995+223.0% | Added |
| JPMorgan Chase & Co | 892,886 | $15.2M | 0.00% | +32,745+3.8% | Added |
| Schroder Investment Management Group | 1,005,984 | $17.3M | 0.01% | +450,440+81.1% | Added |
| Northern Trust Corp | 1,033,068 | $17.6M | 0.00% | +21,318+2.1% | Added |
| Charles Schwab Investment Management Inc | 1,191,361 | $20.3M | 0.00% | +192,989+19.3% | Added |
| RTW Investments, LP | 1,350,000 | $22.9M | 0.23% | +450,000+50.0% | Added |
| Emerald Mutual Fund Advisers Trust | 1,414,665 | $24.0M | 1.17% | −351,397−19.9% | Reduced |
| Bellevue Group AG | 1,490,518 | $25.3M | 0.48% | −2,603,940−63.6% | Reduced |
| First Light Asset Management, LLC | 1,853,851 | $31.5M | 2.41% | +1,853,851 | New |
| Pfizer Inc | 1,875,000 | $31.9M | 13.48% | 00.0% | Unchanged |
| Loomis Sayles & Co L P | 2,040,223 | $34.7M | 0.04% | −865,243−29.8% | Reduced |
| Kynam Capital Management, LP | 2,169,105 | $36.9M | 2.40% | −2,390,948−52.4% | Reduced |
| Siren, L.L.C. | 2,450,000 | $41.6M | 1.24% | −1,246,322−33.7% | Reduced |