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Syros Pharmaceuticals, Inc.

SYRSDelisted Mar 10, 2025
Industry
Pharmaceutical Preparations
SEC CIK
0001556263

Syros Pharmaceuticals, Inc. was delisted on Mar 10, 2025; its insiders filed their last Form 4 on Dec 4, 2024; 44 institutions reported holding it in 13F filings for Q4 2024, worth $1.20M in total; no superinvestor held it.

13F holders, Q2 2021

Institutional positions in Syros Pharmaceuticals, Inc. as of Jun 30, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
100
−6 vs. Q1 2021
Shares held
50.9M
−12.9M (−20.3%) vs. Q1 2021
Total value
$276.0M
−$199.8M (−42.0%) vs. Q1 2021
New holders
19
48 more added
Sold out
25
20 more reduced

Compare with Q1 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting SYRS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2021: 100 institutions
Q1 2021: 106 institutionsQ2 2021: 100 institutionsQ3 2021: 100 institutionsQ4 2021: 90 institutionsQ1 2022: 94 institutionsQ2 2022: 69 institutionsQ3 2022: 53 institutionsQ4 2022: 57 institutionsQ1 2023: 59 institutionsQ2 2023: 53 institutionsQ3 2023: 48 institutionsQ4 2023: 58 institutionsQ1 2024: 75 institutionsQ2 2024: 70 institutionsQ3 2024: 65 institutionsQ4 2024: 44 institutionsQ1 2025: 7 institutionsQ2 2025: 0 institutionsQ3 2025: 0 institutionsQ4 2025: 0 institutionsQ1 2026: 0 institutionsQ2 2026: 0 institutions
Value heldQ2 2021: $276.0M
Q1 2021: $475.8MQ2 2021: $276.0MQ3 2021: $223.1MQ4 2021: $166.0MQ1 2022: $53.1MQ2 2022: $34.2MQ3 2022: $59.9MQ4 2022: $37.9MQ1 2023: $27.5MQ2 2023: $33.5MQ3 2023: $47.9MQ4 2023: $146.8MQ1 2024: $111.9MQ2 2024: $105.2MQ3 2024: $40.8MQ4 2024: $1.20MQ1 2025: $12.4KQ2 2025: $0Q3 2025: $0Q4 2025: $0Q1 2026: $0Q2 2026: $0
Institutions holding SYRS and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20260$0
Q4 20250$0
Q3 20250$0
Q2 20250$0
Q1 20257$12.4K
Q4 202444$1.20M
Q3 202465$40.8M
Q2 202470$105.2M
Q1 202475$111.9M
Q4 202358$146.8M
Q3 202348$47.9M
Q2 202353$33.5M
Q1 202359$27.5M
Q4 202257$37.9M
Q3 202253$59.9M
Q2 202269$34.2M
Q1 202294$53.1M
Q4 202190$166.0M
Q3 2021100$223.1M
Q2 2021100$276.0M
Q1 2021106$475.8M

Institutions, Q2 2021

Shares, value and share of portfolio for each institution holding Syros Pharmaceuticals, Inc.; share changes are against Q1 2021.

Institutions holding SYRS in Q2 2021
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC9,047,965$49.3M0.00%+32,853+0.4%Added
Bain Capital Life Sciences Investors, LLC5,785,036$31.5M2.07%00.0%Unchanged
BlackRock Inc.4,463,356$24.3M0.00%+295,392+7.1%Added
Ally Bridge Group (NY) LLC3,439,895$18.7M5.26%+300,000+9.6%Added
Flagship Pioneering Inc.2,938,494$16.0M0.20%00.0%Unchanged
Vanguard Group Inc2,775,576$15.1M0.00%+43,152+1.6%Added
Omega Fund Management, LLC2,274,831$12.4M1.40%+712,331+45.6%Added
Samsara BioCapital, LLC2,189,199$10.6M1.39%00.0%Unchanged
OrbiMed Advisors LLC1,837,500$10.0M0.10%00.0%Unchanged
Artal Group S.A.1,700,000$9.27M0.21%+675,000+65.9%Added
Altium Capital Management LP1,076,942$5.87M1.36%+950,240+750.0%Added
EcoR1 Capital, LLC1,000,000$5.45M0.20%00.0%Unchanged
State Street Corp999,254$5.45M0.00%+203,909+25.6%Added
Geode Capital Management, LLC966,448$5.27M0.00%+133,440+16.0%Added
Ra Capital Management, L.P.900,000$4.91M0.08%00.0%Unchanged
Adage Capital Partners GP, L.L.C.852,300$4.64M0.01%+852,300New
Sio Capital Management, LLC800,000$4.36M1.18%+800,000New
Candriam Luxembourg S.C.A.584,272$3.18M0.02%+584,272New
Millennium Management LLC557,713$3.04M0.00%+388,920+230.4%Added
Northern Trust Corp554,422$3.02M0.00%+34,517+6.6%Added
Goldman Sachs Group Inc501,221$2.73M0.00%−135,699−21.3%Reduced
Morgan Stanley403,339$2.20M0.00%+29,208+7.8%Added
Charles Schwab Investment Management Inc391,798$2.14M0.00%+28,631+7.9%Added
Acadian Asset Management LLC354,453$1.93M0.01%+354,453New
Dimensional Fund Advisors LP308,651$1.68M0.00%−42,518−12.1%Reduced
Marshall Wace, LLP296,405$1.61M0.01%+296,405New
Los Angeles Capital Management LLC271,508$1.48M0.01%+181,127+200.4%Added
Cubist Systematic Strategies, LLC257,997$1.41M0.02%+231,972+891.3%Added
Two Sigma Advisers, LP256,100$1.40M0.00%−39,700−13.4%Reduced
Bank of New York Mellon Corp186,846$1.02M0.00%+39,489+26.8%Added
JPMorgan Chase & Co183,553$1.00M0.00%−480,352−72.4%Reduced
Nuveen Asset Management, LLC180,514$984.0K0.00%+33,901+23.1%Added
Susquehanna International Group, LLP146,511$798.0K0.00%+56,072+62.0%Added
Gsa Capital Partners LLP140,991$768.0K0.09%+76,161+117.5%Added
Two Sigma Investments, LP120,354$656.0K0.00%−90,021−42.8%Reduced
PDT Partners, LLC116,801$637.0K0.04%−30,641−20.8%Reduced
Assenagon Asset Management S.A.115,785$631.0K0.00%+115,785New
Ensign Peak Advisors, Inc100,000$545.0K0.00%00.0%Unchanged
Engineers Gate Manager LP82,200$448.0K0.03%+82,200New
Alps Advisors Inc81,474$444.0K0.00%−30,036−26.9%Reduced
Citadel Advisors LLC81,248$443.0K0.00%−617,034−88.4%Reduced
Palo Alto Investors LP80,600$439.0K0.02%00.0%Unchanged
California State Teachers Retirement System79,478$433.0K0.00%+8,303+11.7%Added
Qube Research & Technologies Ltd78,774$429.0K0.01%+42,284+115.9%Added
Connor, Clark & Lunn Investment Management Ltd.76,052$414.0K0.00%+76,052New
Baker Bros. Advisors LP65,497$357.0K0.00%−624,670−90.5%Reduced
Rhumbline Advisers64,715$353.0K0.00%+18,017+38.6%Added
QS Investors, LLC64,000$349.0K0.00%00.0%Unchanged
State of Wisconsin Investment Board59,747$326.0K0.00%−23,700−28.4%Reduced
Barclays PLC58,761$320.0K0.00%−18,283−23.7%Reduced
Alliancebernstein L.P.55,900$305.0K0.00%+19,800+54.8%Added
Jane Street Group, LLC53,035$289.0K0.00%+15,237+40.3%Added
ACT Capital Management, LLC52,500$287.0K0.15%+52,500New
Simplex Trading, LLC45,358$247.0K0.01%+22,304+96.7%Added
Jacobs Levy Equity Management, Inc42,555$232.0K0.00%−20,553−32.6%Reduced
Redmile Group, LLC38,912$212.0K0.00%−173,379−81.7%Reduced
LPL Financial LLC38,090$208.0K0.00%+18,762+97.1%Added
Virtus ETF Advisers LLC37,977$207.0K0.09%+12,204+47.4%Added
Manufacturers Life Insurance Company, The36,533$199.0K0.00%+8,128+28.6%Added
Deutsche Bank AG36,158$196.0K0.00%−20,029−35.6%Reduced
New York State Common Retirement Fund34,009$185.0K0.00%+409+1.2%Added
Trexquant Investment LP33,676$184.0K0.02%+16,650+97.8%Added
Bank of America Corp33,014$180.0K0.00%−8,272−20.0%Reduced
American International Group, Inc.32,258$176.0K0.00%+4,756+17.3%Added
Hancock Whitney Corp27,860$152.0K0.00%+16,592+147.2%Added
ProShare Advisors LLC26,050$142.0K0.00%+4,931+23.3%Added
XTX Topco Ltd26,018$142.0K0.05%+14,849+132.9%Added
Tower Research Capital LLC (TRC)25,046$136.0K0.00%−9,454−27.4%Reduced
State Board of Administration of Florida Retirement System23,585$129.0K0.00%+2,190+10.2%Added
Group One Trading, L.P.23,348$127.0K0.00%+23,348New
Voya Investment Management LLC22,675$124.0K0.00%+2,542+12.6%Added
Russell Investments Group, Ltd.20,344$109.0K0.00%−24,064−54.2%Reduced
Parametric Portfolio Associates LLC19,110$104.0K0.00%+19,110New
Invesco Ltd.18,214$99.0K0.00%+7,036+62.9%Added
Raymond James & Associates15,500$84.0K0.00%+15,500New
Principal Financial Group Inc14,226$78.0K0.00%+4,163+41.4%Added
Prelude Capital Management, LLC14,200$77.0K0.00%−400−2.7%Reduced
Caas Capital Management LP13,905$76.0K0.00%+13,905New
UBS Group AG13,417$73.0K0.00%+10,054+299.0%Added
Dynamic Technology Lab Private Ltd13,049$71.0K0.01%+13,049New
Fox Run Management, L.L.C.12,826$70.0K0.06%+12,826New
Citigroup Inc6,489$35.0K0.00%+2,188+50.9%Added
Legal & General Group Plc5,328$29.0K0.00%+180+3.5%Added
Royal Bank of Canada3,941$21.0K0.00%+1,988+101.8%Added
Ameritas Investment Partners, Inc.3,667$20.0K0.00%00.0%Unchanged
Point72 Hong Kong Ltd2,627$14.0K0.00%+225+9.4%Added
BNP Paribas Arbitrage, SA2,149$11.7K0.00%−4,006−65.1%Reduced
Penserra Capital Management LLC1,410$7.00K0.00%+15+1.1%Added
Jacobi Capital Management LLC1,200$7.00K0.00%00.0%Unchanged
US Bancorp1,206$7.00K0.00%+478+65.7%Added
Quantbot Technologies LP1,300$7.00K0.00%+900+225.0%Added
Capital Advisory Group Advisory Services, LLC700$4.00K0.00%+700New
Advisor Group Holdings, Inc.440$3.00K0.00%+40+10.0%Added
Panagora Asset Management Inc428$2.00K0.00%00.0%Unchanged
Wells Fargo & Company147$1.00K0.00%−8,814−98.4%Reduced
Daiwa Securities Group Inc.101$1.00K0.00%00.0%Unchanged
West Oak Capital, LLC100$1.00K0.00%+100New
Signaturefd, LLC171$1.00K0.00%+171New
State of Wyoming216$1.00K0.00%+216New
Ellevest, Inc.20$00.00%+12+150.0%Added