Skip to main content
Livermore
Livermore
ZHEN

Syros Pharmaceuticals, Inc.

SYRSDelisted Mar 10, 2025
Industry
Pharmaceutical Preparations
SEC CIK
0001556263

Syros Pharmaceuticals, Inc. was delisted on Mar 10, 2025; its insiders filed their last Form 4 on Dec 4, 2024; 44 institutions reported holding it in 13F filings for Q4 2024, worth $1.20M in total; no superinvestor held it.

13F holders, Q4 2022

Institutional positions in Syros Pharmaceuticals, Inc. as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
57
+5 vs. Q3 2022
Shares held
10.6M
+1.26M (+13.5%) vs. Q3 2022
Total value
$37.9M
−$22.0M (−36.7%) vs. Q3 2022
New holders
14
12 more added
Sold out
9
14 more reduced

1 institution that held it in Q3 2022 haven't filed for Q4 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting SYRS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2022: 57 institutions
Q1 2021: 106 institutionsQ2 2021: 100 institutionsQ3 2021: 100 institutionsQ4 2021: 90 institutionsQ1 2022: 94 institutionsQ2 2022: 69 institutionsQ3 2022: 53 institutionsQ4 2022: 57 institutionsQ1 2023: 59 institutionsQ2 2023: 53 institutionsQ3 2023: 48 institutionsQ4 2023: 58 institutionsQ1 2024: 75 institutionsQ2 2024: 70 institutionsQ3 2024: 65 institutionsQ4 2024: 44 institutionsQ1 2025: 7 institutionsQ2 2025: 0 institutionsQ3 2025: 0 institutionsQ4 2025: 0 institutionsQ1 2026: 0 institutionsQ2 2026: 0 institutions
Value heldQ4 2022: $37.9M
Q1 2021: $475.8MQ2 2021: $276.0MQ3 2021: $223.1MQ4 2021: $166.0MQ1 2022: $53.1MQ2 2022: $34.2MQ3 2022: $59.9MQ4 2022: $37.9MQ1 2023: $27.5MQ2 2023: $33.5MQ3 2023: $47.9MQ4 2023: $146.8MQ1 2024: $111.9MQ2 2024: $105.2MQ3 2024: $40.8MQ4 2024: $1.20MQ1 2025: $12.4KQ2 2025: $0Q3 2025: $0Q4 2025: $0Q1 2026: $0Q2 2026: $0
Institutions holding SYRS and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20260$0
Q4 20250$0
Q3 20250$0
Q2 20250$0
Q1 20257$12.4K
Q4 202444$1.20M
Q3 202465$40.8M
Q2 202470$105.2M
Q1 202475$111.9M
Q4 202358$146.8M
Q3 202348$47.9M
Q2 202353$33.5M
Q1 202359$27.5M
Q4 202257$37.9M
Q3 202253$59.9M
Q2 202269$34.2M
Q1 202294$53.1M
Q4 202190$166.0M
Q3 2021100$223.1M
Q2 2021100$276.0M
Q1 2021106$475.8M

Institutions, Q4 2022

Shares, value and share of portfolio for each institution holding Syros Pharmaceuticals, Inc.; share changes are against Q3 2022.

Institutions holding SYRS in Q4 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Bain Capital Life Sciences Investors, LLC2,124,694$7.63M0.85%+1,042,290+96.3%Added
Artal Group S.A.1,463,829$5.25M0.30%00.0%Unchanged
Flagship Pioneering Inc.993,848$3.57M0.11%00.0%Unchanged
Avidity Partners Management LP900,000$3.23M0.08%00.0%Unchanged
Samsara BioCapital, LLC881,450$3.16M0.68%00.0%Unchanged
Ally Bridge Group (NY) LLC868,403$3.12M3.03%00.0%Unchanged
Adage Capital Partners GP, L.L.C.721,914$2.59M0.01%00.0%Unchanged
Vanguard Group Inc472,730$1.70M0.00%−14,803−3.0%Reduced
CVI Holdings, LLC425,500$1.53M0.19%00.0%Unchanged
Altium Capital Management LP315,070$1.13M0.58%+315,070New
DAFNA Capital Management LLC265,878$954.5K0.27%00.0%Unchanged
Omega Fund Management, LLC251,270$902.1K0.30%00.0%Unchanged
BlackRock Inc.207,719$745.7K0.00%−37,514−15.3%Reduced
Millennium Management LLC91,473$328.0K0.00%+21,839+31.4%Added
Geode Capital Management, LLC70,516$253.0K0.00%+101+0.1%Added
LGT Capital Partners Ltd.55,000$197.4K0.01%00.0%Unchanged
Renaissance Technologies LLC47,235$170.0K0.00%+3,500+8.0%Added
Susquehanna International Group, LLP43,247$155.3K0.00%+33,042+323.8%Added
LPL Financial LLC40,980$147.1K0.00%+29,145+246.3%Added
ExodusPoint Capital Management, LP34,165$123.0K0.00%+34,165New
State Street Corp33,130$118.9K0.00%−20.0%Reduced
Dimensional Fund Advisors LP30,226$109.0K0.00%+702+2.4%Added
1492 Capital Management LLC21,744$78.1K0.05%+21,744New
Clarius Group, LLC18,620$67.0K0.01%−727−3.8%Reduced
Ergoteles LLC18,181$65.3K0.00%+18,181New
Acadian Asset Management LLC17,742$62.0K0.00%−6,823−27.8%Reduced
Jane Street Group, LLC16,319$58.6K0.00%+16,319New
Northern Trust Corp15,203$54.6K0.00%−30.0%Reduced
HighTower Advisors, LLC15,004$53.0K0.00%+15,004New
Prelude Capital Management, LLC14,399$51.7K0.00%+14,399New
Virtu Financial LLC12,428$45.0K0.01%+12,428New
Goldman Sachs Group Inc12,408$44.5K0.00%+12,408New
Price T Rowe Associates Inc12,150$44.0K0.00%+12,150New
Tower Research Capital LLC (TRC)12,062$43.0K0.00%+9,410+354.8%Added
Two Sigma Investments, LP10,461$37.6K0.00%+10,461New
Denali Advisors LLC7,700$27.6K0.01%+7,700New
Morgan Stanley6,842$24.6K0.00%−2,827−29.2%Reduced
Edmond de Rothschild Holding S.A.4,382$15.7K0.00%00.0%Unchanged
IFP Advisors, Inc793$6.00K0.00%+743+1,486.0%Added
Group One Trading, L.P.1,376$4.94K0.00%+310+29.1%Added
Federated Hermes, Inc.1,217$4.37K0.00%−22,669−94.9%Reduced
Bank of America Corp1,149$4.13K0.00%−7−0.6%Reduced
Simplex Trading, LLC1,289$4.00K0.00%+1,289New
The PNC Financial Services Group, Inc.1,095$3.93K0.00%00.0%Unchanged
Russell Investments Group, Ltd.750$2.69K0.00%00.0%Unchanged
Wells Fargo & Company700$2.51K0.00%+1+0.1%Added
JPMorgan Chase & Co596$2.00K0.00%−116−16.3%Reduced
Advisor Group Holdings, Inc.223$1.00K0.00%−510−69.6%Reduced
Ten Capital Wealth Advisors, LLC219$7860.00%00.0%Unchanged
Fifth Third Bancorp129$4630.00%00.0%Unchanged
Signaturefd, LLC87$3120.00%00.0%Unchanged
US Bancorp40$1440.00%00.0%Unchanged
Heritage Wealth Management, LLC36$1290.00%+18+100.0%Added
FMR LLC12$430.00%−252,017−100.0%Reduced
CarsonAllaria Wealth Management, Ltd.104$00.00%−58−35.8%Reduced
Royal Bank of Canada7$00.00%−29−80.6%Reduced
GWM Advisors LLC15$00.00%+15New
Pathstone Family Office, LLC0$00.00%−21,913−100.0%Sold out
Walleye Capital LLC0$00.00%−12,800−100.0%Sold out
Aquatic Capital Management LLC0$00.00%−800−100.0%Sold out
BNP Paribas Arbitrage, SA0$00.00%−502−100.0%Sold out
Citigroup Inc0$00.00%−111−100.0%Sold out
Daiwa Securities Group Inc.0$00.00%−10−100.0%Sold out
UBS Group AG0$00.00%−50−100.0%Sold out
Bogart Wealth, LLC0$00.00%−15−100.0%Sold out
China Universal Asset Management Co., Ltd.0$00.00%−59−100.0%Sold out
ACT Capital Management, LLC––––Not filed