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Syros Pharmaceuticals, Inc.

SYRSDelisted Mar 10, 2025
Industry
Pharmaceutical Preparations
SEC CIK
0001556263

Syros Pharmaceuticals, Inc. was delisted on Mar 10, 2025; its insiders filed their last Form 4 on Dec 4, 2024; 44 institutions reported holding it in 13F filings for Q4 2024, worth $1.20M in total; no superinvestor held it.

13F holders, Q4 2021

Institutional positions in Syros Pharmaceuticals, Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
90
−10 vs. Q3 2021
Shares held
51.2M
+1.05M (+2.1%) vs. Q3 2021
Total value
$166.0M
−$57.1M (−25.6%) vs. Q3 2021
New holders
12
31 more added
Sold out
22
32 more reduced

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting SYRS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 90 institutions
Q1 2021: 106 institutionsQ2 2021: 100 institutionsQ3 2021: 100 institutionsQ4 2021: 90 institutionsQ1 2022: 94 institutionsQ2 2022: 69 institutionsQ3 2022: 53 institutionsQ4 2022: 57 institutionsQ1 2023: 59 institutionsQ2 2023: 53 institutionsQ3 2023: 48 institutionsQ4 2023: 58 institutionsQ1 2024: 75 institutionsQ2 2024: 70 institutionsQ3 2024: 65 institutionsQ4 2024: 44 institutionsQ1 2025: 7 institutionsQ2 2025: 0 institutionsQ3 2025: 0 institutionsQ4 2025: 0 institutionsQ1 2026: 0 institutionsQ2 2026: 0 institutions
Value heldQ4 2021: $166.0M
Q1 2021: $475.8MQ2 2021: $276.0MQ3 2021: $223.1MQ4 2021: $166.0MQ1 2022: $53.1MQ2 2022: $34.2MQ3 2022: $59.9MQ4 2022: $37.9MQ1 2023: $27.5MQ2 2023: $33.5MQ3 2023: $47.9MQ4 2023: $146.8MQ1 2024: $111.9MQ2 2024: $105.2MQ3 2024: $40.8MQ4 2024: $1.20MQ1 2025: $12.4KQ2 2025: $0Q3 2025: $0Q4 2025: $0Q1 2026: $0Q2 2026: $0
Institutions holding SYRS and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20260$0
Q4 20250$0
Q3 20250$0
Q2 20250$0
Q1 20257$12.4K
Q4 202444$1.20M
Q3 202465$40.8M
Q2 202470$105.2M
Q1 202475$111.9M
Q4 202358$146.8M
Q3 202348$47.9M
Q2 202353$33.5M
Q1 202359$27.5M
Q4 202257$37.9M
Q3 202253$59.9M
Q2 202269$34.2M
Q1 202294$53.1M
Q4 202190$166.0M
Q3 2021100$223.1M
Q2 2021100$276.0M
Q1 2021106$475.8M

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Syros Pharmaceuticals, Inc.; share changes are against Q3 2021.

Institutions holding SYRS in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC9,061,297$29.5M0.00%+2,4520.0%Added
Bain Capital Life Sciences Investors, LLC6,264,420$20.4M1.62%+479,384+8.3%Added
BlackRock Inc.4,232,268$13.8M0.00%−121,404−2.8%Reduced
Ally Bridge Group (NY) LLC3,539,895$11.5M4.03%+100,000+2.9%Added
Artal Group S.A.3,000,000$9.78M0.29%+1,000,000+50.0%Added
Flagship Pioneering Inc.2,938,494$9.58M0.15%00.0%Unchanged
Vanguard Group Inc2,790,373$9.10M0.00%−195,605−6.6%Reduced
Omega Fund Management, LLC2,512,705$8.19M1.16%00.0%Unchanged
Samsara BioCapital, LLC2,189,199$6.24M1.24%00.0%Unchanged
Adage Capital Partners GP, L.L.C.1,900,000$6.19M0.01%+100,000+5.6%Added
OrbiMed Advisors LLC1,837,500$5.99M0.08%00.0%Unchanged
Altium Capital Management LP1,160,000$3.78M1.06%−112,412−8.8%Reduced
State Street Corp1,148,939$3.75M0.00%+33,367+3.0%Added
Geode Capital Management, LLC953,200$3.11M0.00%+95,554+11.1%Added
Sio Capital Management, LLC900,677$2.94M0.89%00.0%Unchanged
Ra Capital Management, L.P.900,000$2.93M0.05%00.0%Unchanged
Candriam Luxembourg S.C.A.584,272$1.91M0.01%00.0%Unchanged
Northern Trust Corp524,880$1.71M0.00%+2010.0%Added
LGT Capital Partners Ltd.500,000$1.63M0.04%+456,612+1,052.4%Added
Goldman Sachs Group Inc494,894$1.61M0.00%+4,393+0.9%Added
Dimensional Fund Advisors LP315,195$1.03M0.00%+109,892+53.5%Added
Los Angeles Capital Management LLC257,690$840.0K0.00%−1,248−0.5%Reduced
Gsa Capital Partners LLP242,132$789.0K0.10%+131,795+119.4%Added
Bank of New York Mellon Corp194,045$633.0K0.00%−2,100−1.1%Reduced
Nuveen Asset Management, LLC180,588$611.0K0.00%−17,990−9.1%Reduced
Bridgeway Capital Management, LLC170,000$554.0K0.01%+170,000New
Susquehanna International Group, LLP166,021$541.0K0.00%−47,232−22.1%Reduced
Federated Hermes, Inc.164,924$538.0K0.00%+164,924New
Charles Schwab Investment Management Inc142,734$466.0K0.00%−560.0%Reduced
Connor, Clark & Lunn Investment Management Ltd.118,632$387.0K0.00%+15,325+14.8%Added
Jacobs Levy Equity Management, Inc103,310$337.0K0.00%+1,664+1.6%Added
Price T Rowe Associates Inc101,284$330.0K0.00%+52,200+106.3%Added
Millennium Management LLC92,300$301.0K0.00%−224,075−70.8%Reduced
Two Sigma Advisers, LP90,600$295.0K0.00%−82,100−47.5%Reduced
State Board of Administration of Florida Retirement System78,535$256.0K0.00%00.0%Unchanged
LPL Financial LLC70,060$228.0K0.00%+22,945+48.7%Added
Barclays PLC69,877$228.0K0.00%+25,014+55.8%Added
Morgan Stanley69,839$227.0K0.00%−159,586−69.6%Reduced
Caxton Associates LP66,827$218.0K0.03%+66,827New
Rhumbline Advisers66,658$217.0K0.00%−113−0.2%Reduced
Citadel Advisors LLC63,345$206.0K0.00%−6,183−8.9%Reduced
Franklin Resources Inc63,000$205.0K0.00%−1,000−1.6%Reduced
Alliancebernstein L.P.52,600$171.0K0.00%−3,300−5.9%Reduced
Two Sigma Investments, LP48,674$159.0K0.00%−42,604−46.7%Reduced
Ensign Peak Advisors, Inc45,000$147.0K0.00%−55,000−55.0%Reduced
Nomura Holdings Inc43,452$142.0K0.00%+43,452New
Bank of America Corp42,497$139.0K0.00%+11,353+36.5%Added
Deutsche Bank AG36,882$120.0K0.00%−23,091−38.5%Reduced
Manufacturers Life Insurance Company, The35,790$117.0K0.00%+1,545+4.5%Added
New York State Common Retirement Fund34,077$111.0K0.00%−203−0.6%Reduced
California State Teachers Retirement System31,093$101.0K0.00%00.0%Unchanged
American International Group, Inc.30,594$100.0K0.00%−915−2.9%Reduced
Ieq Capital, LLC27,800$91.0K0.00%00.0%Unchanged
JPMorgan Chase & Co27,768$91.0K0.00%+1,110+4.2%Added
Wells Fargo & Company27,009$88.0K0.00%+26,862+18,273.5%Added
Jane Street Group, LLC26,603$87.0K0.00%−52,007−66.2%Reduced
UBS Group AG26,659$87.0K0.00%+21,859+455.4%Added
Jump Financial, LLC26,100$85.0K0.01%+26,100New
Tower Research Capital LLC (TRC)25,773$84.0K0.00%+13,600+111.7%Added
Cubist Systematic Strategies, LLC25,316$83.0K0.00%−61,674−70.9%Reduced
Voya Investment Management LLC25,386$83.0K0.00%+2,711+12.0%Added
ACT Capital Management, LLC21,500$70.0K0.05%−31,000−59.0%Reduced
ProShare Advisors LLC21,303$69.0K0.00%+696+3.4%Added
Occudo Quantitative Strategies LP20,038$65.0K0.01%+3,715+22.8%Added
Parametric Portfolio Associates LLC19,556$64.0K0.00%−4,331−18.1%Reduced
Invesco Ltd.19,016$62.0K0.00%−2,827−12.9%Reduced
Citigroup Inc16,526$54.0K0.00%+6,824+70.3%Added
BNP Paribas Arbitrage, SA12,754$41.6K0.00%+2,055+19.2%Added
Royal Bank of Canada12,499$40.0K0.00%+7,617+156.0%Added
SG Americas Securities, LLC12,012$39.0K0.00%−19,084−61.4%Reduced
XTX Topco Ltd11,524$38.0K0.02%+11,524New
Walleye Capital LLC11,000$36.0K0.00%−22,227−66.9%Reduced
Russell Investments Group, Ltd.9,550$30.0K0.00%−739−7.2%Reduced
Legal & General Group Plc5,328$17.0K0.00%00.0%Unchanged
Nisa Investment Advisors, LLC7,260$14.0K0.00%+7,260New
Point72 Hong Kong Ltd3,706$12.0K0.00%−3,356−47.5%Reduced
Ameritas Investment Partners, Inc.3,667$12.0K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.2,440$8.00K0.00%+2,000+454.5%Added
Aquatic Capital Management LLC1,900$6.00K0.01%+1,900New
CarsonAllaria Wealth Management, Ltd.1,626$5.00K0.00%+1,626New
Quantbot Technologies LP1,300$4.00K0.00%+1,300New
State of Wyoming1,022$3.00K0.00%−2−0.2%Reduced
Simplex Trading, LLC385$1.00K0.00%−44,732−99.1%Reduced
US Bancorp400$1.00K0.00%−245−38.0%Reduced
Allspring Global Investments Holdings, LLC361$1.00K0.00%+361New
American Portfolios Advisors259$8440.00%+259New
West Oak Capital, LLC150$00.00%+50+50.0%Added
Daiwa Securities Group Inc.101$00.00%00.0%Unchanged
Bogart Wealth, LLC15$00.00%00.0%Unchanged
IFP Advisors, Inc50––00.0%Unchanged
Marshall Wace, LLP0$00.00%−183,451−100.0%Sold out
PDT Partners, LLC0$00.00%−96,084−100.0%Sold out
Assenagon Asset Management S.A.0$00.00%−87,073−100.0%Sold out
Palo Alto Investors LP0$00.00%−80,600−100.0%Sold out
Alps Advisors Inc0$00.00%−75,904−100.0%Sold out
State of Wisconsin Investment Board0$00.00%−59,747−100.0%Sold out
Redmile Group, LLC0$00.00%−38,912−100.0%Sold out
Virtus ETF Advisers LLC0$00.00%−36,093−100.0%Sold out
Summit Global Investments0$00.00%−31,800−100.0%Sold out
ExodusPoint Capital Management, LP0$00.00%−30,675−100.0%Sold out