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Syros Pharmaceuticals, Inc.

SYRSDelisted Mar 10, 2025
Industry
Pharmaceutical Preparations
SEC CIK
0001556263

Syros Pharmaceuticals, Inc. was delisted on Mar 10, 2025; its insiders filed their last Form 4 on Dec 4, 2024; 44 institutions reported holding it in 13F filings for Q4 2024, worth $1.20M in total; no superinvestor held it.

13F holders, Q3 2021

Institutional positions in Syros Pharmaceuticals, Inc. as of Sep 30, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
100
+1 vs. Q2 2021
Shares held
50.1M
−690.6K (−1.4%) vs. Q2 2021
Total value
$223.1M
−$52.5M (−19.1%) vs. Q2 2021
New holders
16
29 more added
Sold out
15
34 more reduced

1 institution that held it in Q2 2021 haven't filed for Q3 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting SYRS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2021: 100 institutions
Q1 2021: 106 institutionsQ2 2021: 100 institutionsQ3 2021: 100 institutionsQ4 2021: 90 institutionsQ1 2022: 94 institutionsQ2 2022: 69 institutionsQ3 2022: 53 institutionsQ4 2022: 57 institutionsQ1 2023: 59 institutionsQ2 2023: 53 institutionsQ3 2023: 48 institutionsQ4 2023: 58 institutionsQ1 2024: 75 institutionsQ2 2024: 70 institutionsQ3 2024: 65 institutionsQ4 2024: 44 institutionsQ1 2025: 7 institutionsQ2 2025: 0 institutionsQ3 2025: 0 institutionsQ4 2025: 0 institutionsQ1 2026: 0 institutionsQ2 2026: 0 institutions
Value heldQ3 2021: $223.1M
Q1 2021: $475.8MQ2 2021: $276.0MQ3 2021: $223.1MQ4 2021: $166.0MQ1 2022: $53.1MQ2 2022: $34.2MQ3 2022: $59.9MQ4 2022: $37.9MQ1 2023: $27.5MQ2 2023: $33.5MQ3 2023: $47.9MQ4 2023: $146.8MQ1 2024: $111.9MQ2 2024: $105.2MQ3 2024: $40.8MQ4 2024: $1.20MQ1 2025: $12.4KQ2 2025: $0Q3 2025: $0Q4 2025: $0Q1 2026: $0Q2 2026: $0
Institutions holding SYRS and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20260$0
Q4 20250$0
Q3 20250$0
Q2 20250$0
Q1 20257$12.4K
Q4 202444$1.20M
Q3 202465$40.8M
Q2 202470$105.2M
Q1 202475$111.9M
Q4 202358$146.8M
Q3 202348$47.9M
Q2 202353$33.5M
Q1 202359$27.5M
Q4 202257$37.9M
Q3 202253$59.9M
Q2 202269$34.2M
Q1 202294$53.1M
Q4 202190$166.0M
Q3 2021100$223.1M
Q2 2021100$276.0M
Q1 2021106$475.8M

Institutions, Q3 2021

Shares, value and share of portfolio for each institution holding Syros Pharmaceuticals, Inc.; share changes are against Q2 2021.

Institutions holding SYRS in Q3 2021
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC9,058,845$40.5M0.00%+10,880+0.1%Added
Bain Capital Life Sciences Investors, LLC5,785,036$25.9M1.60%00.0%Unchanged
BlackRock Inc.4,353,672$19.5M0.00%−109,684−2.5%Reduced
Ally Bridge Group (NY) LLC3,439,895$15.4M5.04%00.0%Unchanged
Vanguard Group Inc2,985,978$13.3M0.00%+210,402+7.6%Added
Flagship Pioneering Inc.2,938,494$13.1M0.14%00.0%Unchanged
Omega Fund Management, LLC2,512,705$11.2M1.26%+237,874+10.5%Added
Artal Group S.A.2,000,000$8.94M0.22%+300,000+17.6%Added
Samsara BioCapital, LLC2,189,199$8.62M1.43%00.0%Unchanged
OrbiMed Advisors LLC1,837,500$8.21M0.09%00.0%Unchanged
Adage Capital Partners GP, L.L.C.1,800,000$8.05M0.02%+947,700+111.2%Added
Altium Capital Management LP1,272,412$5.69M1.52%+195,470+18.2%Added
State Street Corp1,115,572$4.99M0.00%+116,318+11.6%Added
Sio Capital Management, LLC900,677$4.03M1.30%+100,677+12.6%Added
Ra Capital Management, L.P.900,000$4.02M0.06%00.0%Unchanged
Geode Capital Management, LLC857,646$3.83M0.00%−108,802−11.3%Reduced
Candriam Luxembourg S.C.A.584,272$2.61M0.02%00.0%Unchanged
Northern Trust Corp524,679$2.35M0.00%−29,743−5.4%Reduced
Goldman Sachs Group Inc490,501$2.19M0.00%−10,720−2.1%Reduced
Millennium Management LLC316,375$1.41M0.00%−241,338−43.3%Reduced
Los Angeles Capital Management LLC258,938$1.16M0.01%−12,570−4.6%Reduced
Morgan Stanley229,425$1.02M0.00%−173,914−43.1%Reduced
Nuveen Asset Management, LLC198,578$1.01M0.00%+18,064+10.0%Added
Susquehanna International Group, LLP213,253$953.0K0.00%+66,742+45.6%Added
Dimensional Fund Advisors LP205,303$918.0K0.00%−103,348−33.5%Reduced
Bank of New York Mellon Corp196,145$876.0K0.00%+9,299+5.0%Added
Marshall Wace, LLP183,451$820.0K0.00%−112,954−38.1%Reduced
Two Sigma Advisers, LP172,700$772.0K0.00%−83,400−32.6%Reduced
Charles Schwab Investment Management Inc142,790$639.0K0.00%−249,008−63.6%Reduced
Gsa Capital Partners LLP110,337$493.0K0.05%−30,654−21.7%Reduced
Connor, Clark & Lunn Investment Management Ltd.103,307$462.0K0.00%+27,255+35.8%Added
Jacobs Levy Equity Management, Inc101,646$454.0K0.00%+59,091+138.9%Added
Ensign Peak Advisors, Inc100,000$447.0K0.00%00.0%Unchanged
PDT Partners, LLC96,084$429.0K0.03%−20,717−17.7%Reduced
Two Sigma Investments, LP91,278$408.0K0.00%−29,076−24.2%Reduced
Cubist Systematic Strategies, LLC86,990$389.0K0.00%−171,007−66.3%Reduced
Assenagon Asset Management S.A.87,073$389.0K0.00%−28,712−24.8%Reduced
Palo Alto Investors LP80,600$360.0K0.02%00.0%Unchanged
Jane Street Group, LLC78,610$352.0K0.00%+25,575+48.2%Added
State Board of Administration of Florida Retirement System78,535$351.0K0.00%+54,950+233.0%Added
Alps Advisors Inc75,904$339.0K0.00%−5,570−6.8%Reduced
Citadel Advisors LLC69,528$311.0K0.00%−11,720−14.4%Reduced
Rhumbline Advisers66,771$298.0K0.00%+2,056+3.2%Added
Franklin Resources Inc64,000$286.0K0.00%+64,000New
Deutsche Bank AG59,973$268.0K0.00%+23,815+65.9%Added
State of Wisconsin Investment Board59,747$267.0K0.00%00.0%Unchanged
Simplex Trading, LLC45,117$255.0K0.01%−241−0.5%Reduced
Alliancebernstein L.P.55,900$250.0K0.00%00.0%Unchanged
ACT Capital Management, LLC52,500$235.0K0.12%00.0%Unchanged
Price T Rowe Associates Inc49,084$219.0K0.00%+49,084New
LPL Financial LLC47,115$211.0K0.00%+9,025+23.7%Added
Barclays PLC44,863$200.0K0.00%−13,898−23.7%Reduced
LGT Capital Partners Ltd.43,388$194.0K0.01%+43,388New
Redmile Group, LLC38,912$174.0K0.00%00.0%Unchanged
Virtus ETF Advisers LLC36,093$161.0K0.07%−1,884−5.0%Reduced
Manufacturers Life Insurance Company, The34,245$153.0K0.00%−2,288−6.3%Reduced
New York State Common Retirement Fund34,280$153.0K0.00%+271+0.8%Added
Walleye Capital LLC33,227$149.0K0.00%+33,227New
Summit Global Investments31,800$142.0K0.01%+31,800New
American International Group, Inc.31,509$141.0K0.00%−749−2.3%Reduced
California State Teachers Retirement System31,093$139.0K0.00%−48,385−60.9%Reduced
Bank of America Corp31,144$139.0K0.00%−1,870−5.7%Reduced
SG Americas Securities, LLC31,096$139.0K0.00%+31,096New
ExodusPoint Capital Management, LP30,675$137.0K0.00%+30,675New
Trexquant Investment LP30,162$135.0K0.01%−3,514−10.4%Reduced
Ieq Capital, LLC27,800$124.0K0.00%+27,800New
JPMorgan Chase & Co26,658$120.0K0.00%−156,895−85.5%Reduced
Parametric Portfolio Associates LLC23,887$107.0K0.00%+4,777+25.0%Added
Voya Investment Management LLC22,675$101.0K0.00%00.0%Unchanged
Invesco Ltd.21,843$97.0K0.00%+3,629+19.9%Added
MetLife Investment Management21,697$97.0K0.00%+21,697New
Virtu Financial LLC20,940$94.0K0.01%+20,940New
ProShare Advisors LLC20,607$92.0K0.00%−5,443−20.9%Reduced
Metropolitan Life Insurance Co16,415$73.4K0.00%+16,415New
Occudo Quantitative Strategies LP16,323$73.0K0.01%+16,323New
Dynamic Technology Lab Private Ltd12,690$57.0K0.01%−359−2.8%Reduced
Principal Financial Group Inc12,239$55.0K0.00%−1,987−14.0%Reduced
Tower Research Capital LLC (TRC)12,173$54.0K0.00%−12,873−51.4%Reduced
BNP Paribas Arbitrage, SA10,699$47.8K0.00%+8,550+397.9%Added
Russell Investments Group, Ltd.10,289$45.0K0.00%−10,055−49.4%Reduced
Citigroup Inc9,702$43.0K0.00%+3,213+49.5%Added
Point72 Hong Kong Ltd7,062$32.0K0.00%+4,435+168.8%Added
Legal & General Group Plc5,328$24.0K0.00%00.0%Unchanged
Royal Bank of Canada4,882$22.0K0.00%+941+23.9%Added
UBS Group AG4,800$21.0K0.00%−8,617−64.2%Reduced
Ameritas Investment Partners, Inc.3,667$16.0K0.00%00.0%Unchanged
Penserra Capital Management LLC1,415$6.00K0.00%+5+0.4%Added
Jacobi Capital Management LLC1,200$5.00K0.00%00.0%Unchanged
State of Wyoming1,024$5.00K0.00%+808+374.1%Added
US Bancorp645$3.00K0.00%−561−46.5%Reduced
Lindbrook Capital, LLC514$2.00K0.00%+514New
Advisor Group Holdings, Inc.440$1.00K0.00%00.0%Unchanged
Wells Fargo & Company147$1.00K0.00%00.0%Unchanged
Signaturefd, LLC200$1.00K0.00%+29+17.0%Added
Quadrant Capital Group LLC114$1.00K0.00%+114New
West Oak Capital, LLC100$00.00%00.0%Unchanged
Daiwa Securities Group Inc.101$00.00%00.0%Unchanged
Ellevest, Inc.30$00.00%+10+50.0%Added
Bogart Wealth, LLC15$00.00%+15New
IFP Advisors, Inc50––+50New