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Syros Pharmaceuticals, Inc.

SYRSDelisted Mar 10, 2025
Industry
Pharmaceutical Preparations
SEC CIK
0001556263

Syros Pharmaceuticals, Inc. was delisted on Mar 10, 2025; its insiders filed their last Form 4 on Dec 4, 2024; 44 institutions reported holding it in 13F filings for Q4 2024, worth $1.20M in total; no superinvestor held it.

13F holders, Q1 2024

Institutional positions in Syros Pharmaceuticals, Inc. as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
75
+17 vs. Q4 2023
Shares held
20.9M
+1.67M (+8.7%) vs. Q4 2023
Total value
$111.9M
−$34.9M (−23.8%) vs. Q4 2023
New holders
22
21 more added
Sold out
5
7 more reduced

Compare with Q4 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting SYRS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2024: 75 institutions
Q1 2021: 106 institutionsQ2 2021: 100 institutionsQ3 2021: 100 institutionsQ4 2021: 90 institutionsQ1 2022: 94 institutionsQ2 2022: 69 institutionsQ3 2022: 53 institutionsQ4 2022: 57 institutionsQ1 2023: 59 institutionsQ2 2023: 53 institutionsQ3 2023: 48 institutionsQ4 2023: 58 institutionsQ1 2024: 75 institutionsQ2 2024: 70 institutionsQ3 2024: 65 institutionsQ4 2024: 44 institutionsQ1 2025: 7 institutionsQ2 2025: 0 institutionsQ3 2025: 0 institutionsQ4 2025: 0 institutionsQ1 2026: 0 institutionsQ2 2026: 0 institutions
Value heldQ1 2024: $111.9M
Q1 2021: $475.8MQ2 2021: $276.0MQ3 2021: $223.1MQ4 2021: $166.0MQ1 2022: $53.1MQ2 2022: $34.2MQ3 2022: $59.9MQ4 2022: $37.9MQ1 2023: $27.5MQ2 2023: $33.5MQ3 2023: $47.9MQ4 2023: $146.8MQ1 2024: $111.9MQ2 2024: $105.2MQ3 2024: $40.8MQ4 2024: $1.20MQ1 2025: $12.4KQ2 2025: $0Q3 2025: $0Q4 2025: $0Q1 2026: $0Q2 2026: $0
Institutions holding SYRS and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20260$0
Q4 20250$0
Q3 20250$0
Q2 20250$0
Q1 20257$12.4K
Q4 202444$1.20M
Q3 202465$40.8M
Q2 202470$105.2M
Q1 202475$111.9M
Q4 202358$146.8M
Q3 202348$47.9M
Q2 202353$33.5M
Q1 202359$27.5M
Q4 202257$37.9M
Q3 202253$59.9M
Q2 202269$34.2M
Q1 202294$53.1M
Q4 202190$166.0M
Q3 2021100$223.1M
Q2 2021100$276.0M
Q1 2021106$475.8M

Institutions, Q1 2024

Shares, value and share of portfolio for each institution holding Syros Pharmaceuticals, Inc.; share changes are against Q4 2023.

Institutions holding SYRS in Q1 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Bain Capital Life Sciences Investors, LLC2,749,808$14.7M1.18%00.0%Unchanged
Artal Group S.A.2,505,013$13.4M0.35%00.0%Unchanged
Adage Capital Partners GP, L.L.C.2,071,914$11.1M0.02%00.0%Unchanged
Samsara BioCapital, LLC1,786,427$9.56M1.48%00.0%Unchanged
Avidity Partners Management LP1,673,538$8.95M0.32%00.0%Unchanged
Point72 Asset Management, L.P.1,471,771$7.87M0.02%00.0%Unchanged
Flagship Pioneering Inc.1,293,849$6.92M0.45%+10.0%Added
Vanguard Group Inc928,046$4.97M0.00%+163,234+21.3%Added
Deep Track Capital, LP828,485$4.43M0.13%00.0%Unchanged
Opaleye Management Inc.787,545$4.21M0.92%+428,175+119.1%Added
Goldman Sachs Group Inc446,591$2.39M0.00%+206,910+86.3%Added
Kennedy Capital Management, Inc.404,914$2.17M0.04%+404,914New
Blue Owl Capital Holdings LP340,855$1.82M0.36%−1,152,397−77.2%Reduced
Walleye Capital LLC284,936$1.52M0.02%+284,936New
Millennium Management LLC261,083$1.40M0.00%+261,083New
BlackRock Inc.257,041$1.38M0.00%+10,097+4.1%Added
Omega Fund Management, LLC251,270$1.34M0.87%00.0%Unchanged
Knott David M Jr233,000$1.25M0.44%+153,073+191.5%Added
Geode Capital Management, LLC220,245$1.18M0.00%+58,682+36.3%Added
UBS Oconnor LLC175,000$936.3K0.03%+45,000+34.6%Added
Jane Street Group, LLC172,517$923.0K0.00%+151,382+716.3%Added
Assenagon Asset Management S.A.169,999$909.5K0.00%+144,869+576.5%Added
Marshall Wace, LLP159,584$853.8K0.00%+134,766+543.0%Added
ExodusPoint Capital Management, LP154,989$829.0K0.01%+51,467+49.7%Added
Qube Research & Technologies Ltd137,881$737.7K0.00%+137,881New
DAFNA Capital Management LLC135,850$726.8K0.17%−79,035−36.8%Reduced
Renaissance Technologies LLC119,835$641.0K0.00%+61,200+104.4%Added
Perceptive Advisors LLC116,754$624.6K0.01%+116,754New
LPL Financial LLC76,125$407.3K0.00%−5,400−6.6%Reduced
Two Sigma Investments, LP68,283$365.3K0.00%+13,629+24.9%Added
State Street Corp58,430$312.6K0.00%+9,000+18.2%Added
LGT Capital Partners Ltd.55,000$294.3K0.01%00.0%Unchanged
Bridgeway Capital Management, LLC51,500$275.5K0.01%+12,000+30.4%Added
Man Group plc45,294$242.3K0.00%+45,294New
Northern Trust Corp36,897$197.4K0.00%−3,073−7.7%Reduced
Bank of America Corp33,742$180.5K0.00%+23,721+236.7%Added
Citigroup Inc33,624$179.9K0.00%+33,624New
Balyasny Asset Management LLC23,106$123.6K0.00%+23,106New
Price T Rowe Associates Inc22,550$121.0K0.00%00.0%Unchanged
1492 Capital Management LLC21,744$116.3K0.06%00.0%Unchanged
HRT Financial LP19,591$104.0K0.00%+19,591New
Clarius Group, LLC18,620$99.6K0.01%00.0%Unchanged
Y-Intercept (Hong Kong) Ltd18,463$98.8K0.01%+7,951+75.6%Added
Morgan Stanley17,461$93.4K0.00%+15,842+978.5%Added
Acadian Asset Management LLC17,162$91.0K0.00%+17,162New
Brevan Howard Capital Management LP16,036$85.8K0.01%+16,036New
CIBC Asset Management Inc15,398$82.4K0.00%00.0%Unchanged
HighTower Advisors, LLC14,917$80.0K0.00%−87−0.6%Reduced
Squarepoint Ops LLC14,890$79.7K0.00%+14,890New
American Century Companies Inc13,624$72.9K0.00%+13,624New
CI Private Wealth, LLC12,000$64.2K0.00%00.0%Unchanged
Virtu Financial LLC12,030$64.0K0.00%+12,030New
Omers Administration Corp11,800$63.1K0.00%+11,800New
Two Sigma Advisers, LP11,550$61.8K0.00%+11,550New
XTX Topco Ltd10,949$58.6K0.01%−57−0.5%Reduced
Integrated Wealth Concepts LLC10,000$53.5K0.00%00.0%Unchanged
Federation des caisses Desjardins du Quebec4,500$24.1K0.00%+4,500New
Edmond de Rothschild Holding S.A.4,382$23.4K0.00%00.0%Unchanged
Royal Bank of Canada1,318$7.00K0.00%−1,682−56.1%Reduced
The PNC Financial Services Group, Inc.1,095$5.86K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.1,085$5.80K0.00%+2+0.2%Added
Russell Investments Group, Ltd.750$4.01K0.00%00.0%Unchanged
Rhumbline Advisers659$3.52K0.00%00.0%Unchanged
Wells Fargo & Company617$3.30K0.00%+77+14.3%Added
JPMorgan Chase & Co549$2.94K0.00%00.0%Unchanged
IFP Advisors, Inc438$2.34K0.00%00.0%Unchanged
Simplex Trading, LLC232$1.00K0.00%+232New
Fifth Third Bancorp129$6900.00%00.0%Unchanged
Tower Research Capital LLC (TRC)95$5080.00%+95New
Sound Income Strategies, LLC76$4070.00%00.0%Unchanged
FMR LLC71$3800.00%+71New
UBS Group AG21$1120.00%+21New
PSI Advisors, LLC13$700.00%00.0%Unchanged
Steward Partners Investment Advisory, LLC8$430.00%00.0%Unchanged
Macquarie Group Ltd613$30.00%+613New
Tang Capital Management LLC0$00.00%−85,031−100.0%Sold out
EAM Investors, LLC0$00.00%−84,002−100.0%Sold out
683 Capital Management, LLC0$00.00%−36,444−100.0%Sold out
Citadel Advisors LLC0$00.00%−6,180−100.0%Sold out
Group One Trading, L.P.0$00.00%−1,279−100.0%Sold out