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Syros Pharmaceuticals, Inc.

SYRSDelisted Mar 10, 2025
Industry
Pharmaceutical Preparations
SEC CIK
0001556263

Syros Pharmaceuticals, Inc. was delisted on Mar 10, 2025; its insiders filed their last Form 4 on Dec 4, 2024; 44 institutions reported holding it in 13F filings for Q4 2024, worth $1.20M in total; no superinvestor held it.

13F holders, Q1 2022

Institutional positions in Syros Pharmaceuticals, Inc. as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
94
+4 vs. Q4 2021
Shares held
44.6M
−6.57M (−12.8%) vs. Q4 2021
Total value
$53.1M
−$112.9M (−68.0%) vs. Q4 2021
New holders
15
27 more added
Sold out
11
31 more reduced

Compare with Q4 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting SYRS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2022: 94 institutions
Q1 2021: 106 institutionsQ2 2021: 100 institutionsQ3 2021: 100 institutionsQ4 2021: 90 institutionsQ1 2022: 94 institutionsQ2 2022: 69 institutionsQ3 2022: 53 institutionsQ4 2022: 57 institutionsQ1 2023: 59 institutionsQ2 2023: 53 institutionsQ3 2023: 48 institutionsQ4 2023: 58 institutionsQ1 2024: 75 institutionsQ2 2024: 70 institutionsQ3 2024: 65 institutionsQ4 2024: 44 institutionsQ1 2025: 7 institutionsQ2 2025: 0 institutionsQ3 2025: 0 institutionsQ4 2025: 0 institutionsQ1 2026: 0 institutionsQ2 2026: 0 institutions
Value heldQ1 2022: $53.1M
Q1 2021: $475.8MQ2 2021: $276.0MQ3 2021: $223.1MQ4 2021: $166.0MQ1 2022: $53.1MQ2 2022: $34.2MQ3 2022: $59.9MQ4 2022: $37.9MQ1 2023: $27.5MQ2 2023: $33.5MQ3 2023: $47.9MQ4 2023: $146.8MQ1 2024: $111.9MQ2 2024: $105.2MQ3 2024: $40.8MQ4 2024: $1.20MQ1 2025: $12.4KQ2 2025: $0Q3 2025: $0Q4 2025: $0Q1 2026: $0Q2 2026: $0
Institutions holding SYRS and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20260$0
Q4 20250$0
Q3 20250$0
Q2 20250$0
Q1 20257$12.4K
Q4 202444$1.20M
Q3 202465$40.8M
Q2 202470$105.2M
Q1 202475$111.9M
Q4 202358$146.8M
Q3 202348$47.9M
Q2 202353$33.5M
Q1 202359$27.5M
Q4 202257$37.9M
Q3 202253$59.9M
Q2 202269$34.2M
Q1 202294$53.1M
Q4 202190$166.0M
Q3 2021100$223.1M
Q2 2021100$276.0M
Q1 2021106$475.8M

Institutions, Q1 2022

Shares, value and share of portfolio for each institution holding Syros Pharmaceuticals, Inc.; share changes are against Q4 2021.

Institutions holding SYRS in Q1 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Bain Capital Life Sciences Investors, LLC6,264,420$7.46M0.72%00.0%Unchanged
FMR LLC5,526,376$6.58M0.00%−3,534,921−39.0%Reduced
BlackRock Inc.4,170,141$4.96M0.00%−62,127−1.5%Reduced
Artal Group S.A.3,500,000$4.17M0.18%+500,000+16.7%Added
Ally Bridge Group (NY) LLC3,364,895$4.00M2.97%−175,000−4.9%Reduced
Flagship Pioneering Inc.2,938,494$3.50M0.08%00.0%Unchanged
Omega Fund Management, LLC2,512,705$2.99M0.61%00.0%Unchanged
Vanguard Group Inc2,255,530$2.69M0.00%−534,843−19.2%Reduced
Samsara BioCapital, LLC1,899,616$2.26M0.57%−289,583−13.2%Reduced
Adage Capital Partners GP, L.L.C.1,900,000$2.26M0.00%00.0%Unchanged
State Street Corp1,139,351$1.36M0.00%−9,588−0.8%Reduced
Geode Capital Management, LLC985,231$1.17M0.00%+32,031+3.4%Added
Sio Capital Management, LLC902,907$1.07M0.43%+2,230+0.2%Added
Renaissance Technologies LLC818,962$975.0K0.00%+818,962New
Candriam Luxembourg S.C.A.584,272$695.0K0.00%00.0%Unchanged
Millennium Management LLC511,824$609.0K0.00%+419,524+454.5%Added
LGT Capital Partners Ltd.500,000$595.0K0.02%00.0%Unchanged
Northern Trust Corp487,083$579.0K0.00%−37,797−7.2%Reduced
Gsa Capital Partners LLP372,208$443.0K0.06%+130,076+53.7%Added
Los Angeles Capital Management LLC249,473$297.0K0.00%−8,217−3.2%Reduced
Federated Hermes, Inc.240,239$286.0K0.00%+75,315+45.7%Added
Dimensional Fund Advisors LP221,071$263.0K0.00%−94,124−29.9%Reduced
Goldman Sachs Group Inc216,602$257.0K0.00%−278,292−56.2%Reduced
Bank of New York Mellon Corp190,319$227.0K0.00%−3,726−1.9%Reduced
Two Sigma Investments, LP186,366$222.0K0.00%+137,692+282.9%Added
Nuveen Asset Management, LLC183,253$202.0K0.00%+2,665+1.5%Added
Bridgeway Capital Management, LLC170,000$202.0K0.00%00.0%Unchanged
Connor, Clark & Lunn Investment Management Ltd.137,156$163.0K0.00%+18,524+15.6%Added
Charles Schwab Investment Management Inc126,988$152.0K0.00%−15,746−11.0%Reduced
Citadel Advisors LLC128,102$152.0K0.00%+64,757+102.2%Added
D. E. Shaw & Co., Inc.121,809$145.0K0.00%+121,809New
LPL Financial LLC121,135$144.0K0.00%+51,075+72.9%Added
Two Sigma Advisers, LP106,700$127.0K0.00%+16,100+17.8%Added
Jacobs Levy Equity Management, Inc88,811$106.0K0.00%−14,499−14.0%Reduced
Mirabella Financial Services LLP85,900$102.0K0.01%+85,900New
Acadian Asset Management LLC82,354$97.0K0.00%+82,354New
Marshall Wace, LLP81,891$97.0K0.00%+81,891New
Price T Rowe Associates Inc80,884$96.0K0.00%−20,400−20.1%Reduced
Morgan Stanley80,577$95.0K0.00%+10,738+15.4%Added
State Board of Administration of Florida Retirement System78,535$93.0K0.00%00.0%Unchanged
Rhumbline Advisers63,865$76.0K0.00%−2,793−4.2%Reduced
Franklin Resources Inc63,000$75.0K0.00%00.0%Unchanged
Walleye Capital LLC56,088$67.0K0.00%+45,088+409.9%Added
Alliancebernstein L.P.52,800$63.0K0.00%+200+0.4%Added
Ensign Peak Advisors, Inc45,000$54.0K0.00%00.0%Unchanged
XTX Topco Ltd44,555$53.0K0.02%+33,031+286.6%Added
Voya Investment Management LLC39,743$47.0K0.00%+14,357+56.6%Added
ACT Capital Management, LLC35,000$42.0K0.04%+13,500+62.8%Added
New York State Common Retirement Fund34,216$41.0K0.00%+139+0.4%Added
JPMorgan Chase & Co34,537$41.0K0.00%+6,769+24.4%Added
Deutsche Bank AG33,164$39.0K0.00%−3,718−10.1%Reduced
Tower Research Capital LLC (TRC)32,765$39.0K0.00%+6,992+27.1%Added
Walleye Trading LLC30,000$36.0K0.00%+30,000New
Bank of America Corp28,057$34.0K0.00%−14,440−34.0%Reduced
American International Group, Inc.28,582$34.0K0.00%−2,012−6.6%Reduced
Ieq Capital, LLC27,800$33.0K0.00%00.0%Unchanged
Susquehanna International Group, LLP26,328$31.0K0.00%−139,693−84.1%Reduced
California State Teachers Retirement System24,772$29.0K0.00%−6,321−20.3%Reduced
Sawtooth Solutions, LLC23,955$29.0K0.00%+23,955New
Private Advisor Group, LLC24,157$29.0K0.00%+24,157New
Cubist Systematic Strategies, LLC20,554$24.0K0.00%−4,762−18.8%Reduced
Occudo Quantitative Strategies LP20,038$24.0K0.00%00.0%Unchanged
Invesco Ltd.19,109$23.0K0.00%+93+0.5%Added
AQR Capital Management LLC18,636$22.0K0.00%+18,636New
ProShare Advisors LLC17,205$21.0K0.00%−4,098−19.2%Reduced
Schonfeld Strategic Advisors LLC15,100$18.0K0.00%+15,100New
Group One Trading, L.P.14,229$17.0K0.00%+14,229New
Jane Street Group, LLC13,804$16.0K0.00%−12,799−48.1%Reduced
Virtu Financial LLC12,523$15.0K0.00%+12,523New
Parametric Portfolio Associates LLC11,874$14.0K0.00%−7,682−39.3%Reduced
Barclays PLC9,347$11.0K0.00%−60,530−86.6%Reduced
Amalgamated Bank8,113$10.0K0.00%+8,113New
Amalgamated Financial Corp.8,113$10.0K0.00%+8,113New
Russell Investments Group, Ltd.9,041$9.00K0.00%−509−5.3%Reduced
Wells Fargo & Company6,621$8.00K0.00%−20,388−75.5%Reduced
BNP Paribas Arbitrage, SA5,404$6.43K0.00%−7,350−57.6%Reduced
Legal & General Group Plc5,328$6.00K0.00%00.0%Unchanged
Point72 Hong Kong Ltd4,732$6.00K0.00%+1,026+27.7%Added
Aquatic Capital Management LLC5,400$6.00K0.01%+3,500+184.2%Added
Citigroup Inc3,616$4.00K0.00%−12,910−78.1%Reduced
Royal Bank of Canada3,537$4.00K0.00%−8,962−71.7%Reduced
Ameritas Investment Partners, Inc.3,667$4.00K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.3,300$3.00K0.00%+860+35.2%Added
CarsonAllaria Wealth Management, Ltd.1,626$2.00K0.00%00.0%Unchanged
UBS Group AG500$1.00K0.00%−26,159−98.1%Reduced
Quantbot Technologies LP1,300$1.00K0.00%00.0%Unchanged
Allspring Global Investments Holdings, LLC867$1.00K0.00%+506+140.2%Added
American Portfolios Advisors259$3080.00%00.0%Unchanged
US Bancorp400$00.00%00.0%Unchanged
West Oak Capital, LLC150$00.00%00.0%Unchanged
Daiwa Securities Group Inc.101$00.00%00.0%Unchanged
Bogart Wealth, LLC15$00.00%00.0%Unchanged
Captrust Financial Advisors75$00.00%+75New
IFP Advisors, Inc100––+50+100.0%Added
OrbiMed Advisors LLC0$00.00%−1,837,500−100.0%Sold out
Altium Capital Management LP0$00.00%−1,160,000−100.0%Sold out
Ra Capital Management, L.P.0$00.00%−900,000−100.0%Sold out
Caxton Associates LP0$00.00%−66,827−100.0%Sold out
Nomura Holdings Inc0$00.00%−43,452−100.0%Sold out
Manufacturers Life Insurance Company, The0$00.00%−35,790−100.0%Sold out