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Syros Pharmaceuticals, Inc.

SYRSDelisted Mar 10, 2025
Industry
Pharmaceutical Preparations
SEC CIK
0001556263

Syros Pharmaceuticals, Inc. was delisted on Mar 10, 2025; its insiders filed their last Form 4 on Dec 4, 2024; 44 institutions reported holding it in 13F filings for Q4 2024, worth $1.20M in total; no superinvestor held it.

13F holders, Q4 2023

Institutional positions in Syros Pharmaceuticals, Inc. as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
58
+11 vs. Q3 2023
Shares held
19.2M
+8.41M (+77.6%) vs. Q3 2023
Total value
$146.8M
+$104.0M (+242.9%) vs. Q3 2023
New holders
16
16 more added
Sold out
5
8 more reduced

1 institution that held it in Q3 2023 haven't filed for Q4 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting SYRS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2023: 58 institutions
Q1 2021: 106 institutionsQ2 2021: 100 institutionsQ3 2021: 100 institutionsQ4 2021: 90 institutionsQ1 2022: 94 institutionsQ2 2022: 69 institutionsQ3 2022: 53 institutionsQ4 2022: 57 institutionsQ1 2023: 59 institutionsQ2 2023: 53 institutionsQ3 2023: 48 institutionsQ4 2023: 58 institutionsQ1 2024: 75 institutionsQ2 2024: 70 institutionsQ3 2024: 65 institutionsQ4 2024: 44 institutionsQ1 2025: 7 institutionsQ2 2025: 0 institutionsQ3 2025: 0 institutionsQ4 2025: 0 institutionsQ1 2026: 0 institutionsQ2 2026: 0 institutions
Value heldQ4 2023: $146.8M
Q1 2021: $475.8MQ2 2021: $276.0MQ3 2021: $223.1MQ4 2021: $166.0MQ1 2022: $53.1MQ2 2022: $34.2MQ3 2022: $59.9MQ4 2022: $37.9MQ1 2023: $27.5MQ2 2023: $33.5MQ3 2023: $47.9MQ4 2023: $146.8MQ1 2024: $111.9MQ2 2024: $105.2MQ3 2024: $40.8MQ4 2024: $1.20MQ1 2025: $12.4KQ2 2025: $0Q3 2025: $0Q4 2025: $0Q1 2026: $0Q2 2026: $0
Institutions holding SYRS and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20260$0
Q4 20250$0
Q3 20250$0
Q2 20250$0
Q1 20257$12.4K
Q4 202444$1.20M
Q3 202465$40.8M
Q2 202470$105.2M
Q1 202475$111.9M
Q4 202358$146.8M
Q3 202348$47.9M
Q2 202353$33.5M
Q1 202359$27.5M
Q4 202257$37.9M
Q3 202253$59.9M
Q2 202269$34.2M
Q1 202294$53.1M
Q4 202190$166.0M
Q3 2021100$223.1M
Q2 2021100$276.0M
Q1 2021106$475.8M

Institutions, Q4 2023

Shares, value and share of portfolio for each institution holding Syros Pharmaceuticals, Inc.; share changes are against Q3 2023.

Institutions holding SYRS in Q4 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Bain Capital Life Sciences Investors, LLC2,749,808$21.4M2.05%+625,114+29.4%Added
Artal Group S.A.2,505,013$19.5M0.67%+1,029,269+69.7%Added
Adage Capital Partners GP, L.L.C.2,071,914$16.1M0.03%+1,350,000+187.0%Added
Samsara BioCapital, LLC1,786,427$13.9M2.16%+904,977+102.7%Added
Avidity Partners Management LP1,673,538$13.0M0.50%+92,396+5.8%Added
Point72 Asset Management, L.P.1,471,771$11.5M0.03%+1,471,771New
Flagship Pioneering Inc.1,293,848$10.1M0.76%+300,000+30.2%Added
Blue Owl Capital Holdings LP1,493,252$8.46M2.02%+1,493,252New
Deep Track Capital, LP828,485$6.45M0.23%00.0%Unchanged
Vanguard Group Inc764,812$5.96M0.00%+236,620+44.8%Added
Opaleye Management Inc.359,370$2.80M0.75%+359,370New
Omega Fund Management, LLC251,270$1.96M1.59%00.0%Unchanged
BlackRock Inc.246,944$1.92M0.00%+1,199+0.5%Added
Goldman Sachs Group Inc239,681$1.87M0.00%+133,149+125.0%Added
DAFNA Capital Management LLC214,885$1.67M0.40%−50,993−19.2%Reduced
Geode Capital Management, LLC161,563$1.26M0.00%+23,698+17.2%Added
UBS Oconnor LLC130,000$1.01M0.03%+130,000New
ExodusPoint Capital Management, LP103,522$806.0K0.01%−4,615−4.3%Reduced
Tang Capital Management LLC85,031$662.4K0.06%+85,031New
EAM Investors, LLC84,002$654.4K0.12%+84,002New
LPL Financial LLC81,525$635.1K0.00%−8,650−9.6%Reduced
Knott David M Jr79,927$623.0K0.24%−26,048−24.6%Reduced
Renaissance Technologies LLC58,635$457.0K0.00%+9,400+19.1%Added
LGT Capital Partners Ltd.55,000$428.4K0.01%00.0%Unchanged
Two Sigma Investments, LP54,654$425.8K0.00%+54,654New
State Street Corp49,430$385.1K0.00%+16,300+49.2%Added
Northern Trust Corp39,970$311.4K0.00%+13,576+51.4%Added
Bridgeway Capital Management, LLC39,500$307.7K0.01%00.0%Unchanged
683 Capital Management, LLC36,444$283.9K0.03%+36,444New
Assenagon Asset Management S.A.25,130$195.8K0.00%00.0%Unchanged
Marshall Wace, LLP24,818$193.3K0.00%+24,818New
Price T Rowe Associates Inc22,550$176.0K0.00%00.0%Unchanged
1492 Capital Management LLC21,744$169.4K0.10%00.0%Unchanged
Jane Street Group, LLC21,135$164.6K0.00%+21,135New
Clarius Group, LLC18,620$145.1K0.01%00.0%Unchanged
CIBC Asset Management Inc15,398$120.0K0.00%00.0%Unchanged
HighTower Advisors, LLC15,004$117.0K0.00%00.0%Unchanged
CI Private Wealth, LLC12,000$93.5K0.00%−14,666−55.0%Reduced
XTX Topco Ltd11,006$85.7K0.02%+11,006New
Y-Intercept (Hong Kong) Ltd10,512$81.9K0.01%+10,512New
Bank of America Corp10,021$78.1K0.00%+9,953+14,636.8%Added
Integrated Wealth Concepts LLC10,000$77.9K0.00%+10,000New
Citadel Advisors LLC6,180$48.1K0.00%+6,180New
Edmond de Rothschild Holding S.A.4,382$34.1K0.00%00.0%Unchanged
Royal Bank of Canada3,000$23.0K0.00%+2,058+218.5%Added
Morgan Stanley1,619$12.6K0.00%−3,079−65.5%Reduced
Group One Trading, L.P.1,279$9.96K0.00%00.0%Unchanged
The PNC Financial Services Group, Inc.1,095$8.53K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.1,083$8.44K0.00%+787+265.9%Added
Russell Investments Group, Ltd.750$5.84K0.00%00.0%Unchanged
Rhumbline Advisers659$5.13K0.00%00.0%Unchanged
JPMorgan Chase & Co549$4.28K0.00%−528−49.0%Reduced
Wells Fargo & Company540$4.20K0.00%−101−15.8%Reduced
IFP Advisors, Inc438$3.41K0.00%00.0%Unchanged
Fifth Third Bancorp129$1.00K0.00%00.0%Unchanged
Sound Income Strategies, LLC76$5920.00%00.0%Unchanged
PSI Advisors, LLC13$1010.00%+13New
Steward Partners Investment Advisory, LLC8$620.00%+8New
Shay Capital LLC0$00.00%−23,776−100.0%Sold out
UBS Group AG0$00.00%−1,093−100.0%Sold out
FMR LLC0$00.00%−346−100.0%Sold out
Farther Finance Advisors, LLC0$00.00%−20−100.0%Sold out
CWM, LLC0$00.00%−18−100.0%Sold out
CHI Advisors LLC––––Not filed