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CHI Advisors LLC

SEC CIK
0001791468
Latest filing
Nov 13, 2023

The latest 13F from CHI Advisors LLC covers Q3 2023 (filed Nov 13, 2023): 26 long positions worth $252.1M. The top 10 holdings make up 81.4% of the portfolio, and the largest is Pliant Therapeutics, Inc. (PLRX) at 20.7%. Livermore has 12 filings on Form 13F from this institution, going back to Q1 2021.

What changed in Q3 2023

Share counts compared with Q2 2023: how many positions were new, added to, reduced or sold out, and the biggest buys and sells. Dollar amounts are estimated at the quarter-end prices implied by the filing.

Full comparison
New
4
Est. +$16.6M
Added
8
Est. +$21.5M
Reduced
8
Est. −$13.9M
Sold out
3
Est. −$48.1M

Top 5 holdings

Share of this quarter's portfolio value

  1. PLRXPliant Therapeutics, Inc.
    20.7%$52.3MHistory
  2. RPTXRepare Therapeutics Inc.
    14.2%$35.8MHistory
  3. CGEMCullinan Therapeutics, Inc.
    12.3%$30.9MHistory
  4. SLRNACELYRIN, Inc.
    9.1%$23.0MHistory
  5. ORTXOrchard Therapeutics plc
    5.6%$14.0MHistory

Biggest buys

New and added positions, by estimated amount bought

  1. ORTXOrchard Therapeutics plc
    +$13.2MAddedHistory
  2. MLYSMineralys Therapeutics, Inc.
    +$5.41MNewHistory
  3. BPMCBlueprint Medicines Corp
    +$4.66MNewHistory
  4. RAREUltragenyx Pharmaceutical Inc.
    +$4.63MAddedHistory
  5. MLTXMoonLake Immunotherapeutics
    +$3.42MNewHistory

Largest weight increases

New and added positions, by percentage points of the portfolio gained

  1. ORTXOrchard Therapeutics plc
    +4.37 pp1.2% → 5.6%History
  2. MLYSMineralys Therapeutics, Inc.
    +2.14 pp0.0% → 2.1%History
  3. BPMCBlueprint Medicines Corp
    +1.85 pp0.0% → 1.9%History
  4. RAREUltragenyx Pharmaceutical Inc.
    +1.85 pp1.2% → 3.0%History
  5. MLTXMoonLake Immunotherapeutics
    +1.36 pp0.0% → 1.4%History

Biggest sells

Reduced and sold-out positions, by estimated amount sold

  1. Vectivbio Hldg AGH9060V101
    −$46.9MSold out
  2. IRONDisc Medicine, Inc.
    −$4.70MReducedHistory
  3. SLRNACELYRIN, Inc.
    −$4.08MReducedHistory
  4. Direxion Shs ETF Tr25460G716
    −$2.06MReduced
  5. PLRXPliant Therapeutics, Inc.
    −$1.78MReducedHistory

Largest weight decreases

Reduced and sold-out positions, by percentage points of the portfolio lost

  1. Vectivbio Hldg AGH9060V101
    −14.25 pp14.3% → 0.0%
  2. SLRNACELYRIN, Inc.
    −7.77 pp16.9% → 9.1%History
  3. IRONDisc Medicine, Inc.
    −1.22 pp1.7% → 0.5%History
  4. RLYBRallybio Corp
    −0.41 pp0.9% → 0.5%History
  5. BDTXBlack Diamond Therapeutics, Inc.
    −0.33 pp1.1% → 0.8%History

Metrics

13F metrics for Q3 2023, computed only from the numbers in the filings. Definitions below.

Portfolio value
$252.1M
−$77.3M (−23.5%) vs. prior quarter
Positions
26
+1 vs. prior quarter
Top 10 concentration
81.4%
Top 10 as share of value
Turnover
13.1%
Q3 2023, one quarter
Average holding period
8.1 quarters
Weighted by value

How these are calculated

  • Portfolio value: the market value of all long positions in the 13F, as reported at quarter end, excluding options.
  • Top 10 concentration: the combined value of the 10 largest positions as a share of portfolio value.
  • Turnover: the smaller of this quarter's estimated purchases and estimated sales, divided by the average of this and last quarter's portfolio value. Estimates multiply the change in shares by the quarter-end price implied by the filing (market value divided by shares); new positions use this quarter's value and sold-out positions last quarter's. Only positions reported in shares count, and it is not calculated when the previous quarter was not filed.
  • Average holding period: how many consecutive quarters each current position has been held (including this one; a quarter without the position or without a filing starts the count over), weighted by this quarter's value. Counting starts with the first 13F in Livermore (Q1 2021), so positions held before then are understated.

13F filings by quarter

11 quarters, going back to Q1 2021. Bars show each quarter's 13F portfolio value; quarters without a filing are left blank.

Peak $499.5M (Q1 2021)

Q1 2021: $499.5MQ2 2021: $429.9MQ3 2021: $342.6MQ4 2021: $301.3MQ1 2022: $235.0MQ2 2022: $261.5MQ3 2022: $371.9MQ4 2022: $375.4MQ1 2023: $376.6MQ2 2023: $329.4MQ3 2023: $252.1M
Q1 2021Q3 2023
13F filings of CHI Advisors LLC by quarter
QuarterFiledPositionsValueTop 3 holdingsChangesFiling
Q3 2023Nov 13, 202326$252.1MPLRXRPTXCGEMvs. Q2 2023SEC
Q2 2023Aug 22, 2023Amended25$329.4MPLRXSLRNVectivbio Hldg AGvs. Q1 2023SEC
Q1 2023May 11, 202323$376.6MRXDXPLRXVectivbio Hldg AGvs. Q4 2022SEC
Q4 2022Feb 13, 202322$375.4MRXDXPLRXVectivbio Hldg AGvs. Q3 2022SEC
Q3 2022Nov 9, 202225$371.9MRXDXPLRXCGEMvs. Q2 2022SEC
Q2 2022Aug 12, 202225$261.5MRXDXCGEMRPTXvs. Q1 2022SEC
Q1 2022May 16, 202221$235.0MRXDXRPTXCGEMvs. Q4 2021SEC
Q4 2021Feb 11, 202220$301.3MRXDXRPTXCGEMvs. Q3 2021SEC
Q3 2021Nov 15, 202119$342.6MRXDXRPTXCGEMvs. Q2 2021SEC
Q2 2021Aug 11, 202118$429.9MRPTXRXDXPLRXvs. Q1 2021SEC
Q1 2021May 14, 202121$499.5MCGEMPLRXRPTX–SEC

13D and 13G filings

Companies where CHI Advisors LLC reports owning 5% or more on Schedule 13D or 13G, and its latest filings.

Current stakes of 5% or more

CHI Advisors LLC does not currently report owning 5% or more of any company.

Latest filings

22 filings on file made by CHI Advisors LLC or listing it as a reporting person; the latest 20 are shown.

Schedule 13D and 13G filings by CHI Advisors LLC
CompanyFiled (ET)FormStakeChangeEvent dateFiling
INZYInozyme Pharma, Inc.Feb 13, 202313GOld format–New–SEC
VectivBio Holding AGFeb 13, 202313G/AOld format–––SEC
RPTXRepare Therapeutics Inc.Feb 13, 202313G/AOld format–––SEC
PLRXPliant Therapeutics, Inc.Feb 13, 202313G/AOld format–––SEC
ORTXOrchard Therapeutics plcFeb 13, 202313G/AOld format–––SEC
ONCROncorus, Inc.Feb 13, 202313G/AOld format–––SEC
LRMRLarimar Therapeutics, Inc.Feb 13, 202313G/AOld format–––SEC
CRVSCorvus Pharmaceuticals, Inc.Feb 13, 202313GOld format–New–SEC
Freeline Therapeutics Holdings plcFeb 13, 202313G/AOld format–––SEC
CGEMCullinan Therapeutics, Inc.Feb 13, 202313G/AOld format–––SEC
ORTXOrchard Therapeutics plcFeb 11, 202213GOld format–New–SEC
Freeline Therapeutics Holdings plcFeb 11, 202213GOld format–New–SEC
VectivBio Holding AGFeb 11, 202213GOld format–New–SEC
RPTXRepare Therapeutics Inc.Feb 11, 202213G/AOld format–––SEC
PLRXPliant Therapeutics, Inc.Feb 11, 202213G/AOld format–––SEC
ONCROncorus, Inc.Feb 11, 202213G/AOld format–––SEC
LRMRLarimar Therapeutics, Inc.Feb 11, 202213G/AOld format–––SEC
CGEMCullinan Therapeutics, Inc.Feb 11, 202213GOld format–New–SEC
PLRXPliant Therapeutics, Inc.Mar 2, 202113GOld format–New–SEC
RPTXRepare Therapeutics Inc.Mar 2, 202113GOld format–New–SEC