Septerna, Inc.
SEPN- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001984086
In the last 90 days, Septerna, Inc. insiders filed 0 open-market purchases and 7 sales; 153 institutions reported holding it in 13F filings for Q2 2026, worth $1.58B in total; no superinvestor holds it.
13F holders, Q4 2024
Institutional positions in Septerna, Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 71
- +71 vs. Q3 2024
- Shares held
- 44.1M
- +44.1M vs. Q3 2024
- Total value
- $1.01B
- +$1.01B vs. Q3 2024
- New holders
- 71
- 0 more added
- Sold out
- 0
- 0 more reduced
Compare with Q3 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting SEPN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 153 | $1.58B |
| Q1 2026 | 124 | $1.10B |
| Q4 2025 | 122 | $1.27B |
| Q3 2025 | 82 | $838.0M |
| Q2 2025 | 89 | $469.6M |
| Q1 2025 | 71 | $262.2M |
| Q4 2024 | 71 | $1.01B |
| Q3 2024 | 0 | $0 |
| Q2 2024 | 0 | $0 |
| Q1 2024 | 0 | $0 |
| Q4 2023 | 0 | $0 |
| Q3 2023 | 0 | $0 |
| Q2 2023 | 0 | $0 |
| Q1 2023 | 0 | $0 |
| Q4 2022 | 0 | $0 |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q4 2024
Shares, value and share of portfolio for each institution holding Septerna, Inc.; share changes are against Q3 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| GAMMA Investing LLC | 15 | $344 | 0.00% | +15 | New |
| Sterling Capital Management LLC | 266 | $6.09K | 0.00% | +266 | New |
| Amalgamated Bank | 634 | $15.0K | 0.00% | +634 | New |
| Tower Research Capital LLC (TRC) | 1,093 | $25.0K | 0.00% | +1,093 | New |
| California State Teachers Retirement System | 1,370 | $31.4K | 0.00% | +1,370 | New |
| Royal Bank of Canada | 1,398 | $32.0K | 0.00% | +1,398 | New |
| New York State Common Retirement Fund | 1,400 | $32.1K | 0.00% | +1,400 | New |
| Legal & General Group Plc | 1,840 | $42.1K | 0.00% | +1,840 | New |
| Ameritas Investment Partners, Inc. | 1,944 | $44.5K | 0.00% | +1,944 | New |
| BNP Paribas Arbitrage, SA | 2,251 | $51.5K | 0.00% | +2,251 | New |
| The PNC Financial Services Group, Inc. | 2,680 | $61.4K | 0.00% | +2,680 | New |
| STRS Ohio | 3,400 | $77.9K | 0.00% | +3,400 | New |
| SG Americas Securities, LLC | 8,095 | $185.0K | 0.00% | +8,095 | New |
| Corebridge Financial, Inc. | 9,236 | $211.5K | 0.00% | +9,236 | New |
| Soros Fund Management LLCSuperinvestorSoros Fund Management | 10,000 | $229.0K | 0.00% | +10,000 | New |
| Zimmer Partners, LP | 10,000 | $229.0K | 0.00% | +10,000 | New |
| Deutsche Bank AG | 10,419 | $238.6K | 0.00% | +10,419 | New |
| Mirae Asset Global ETFs Holdings Ltd. | 10,519 | $240.9K | 0.00% | +10,519 | New |
| Wells Fargo & Company | 10,651 | $243.9K | 0.00% | +10,651 | New |
| MetLife Investment Management | 11,555 | $264.6K | 0.00% | +11,555 | New |
| UBS Oconnor LLC | 12,118 | $277.5K | 0.01% | +12,118 | New |
| Invesco Ltd. | 12,154 | $278.3K | 0.00% | +12,154 | New |
| Citigroup Inc | 14,633 | $335.1K | 0.00% | +14,633 | New |
| M&T Bank Corp | 16,394 | $375.7K | 0.00% | +16,394 | New |
| Rhumbline Advisers | 19,995 | $457.9K | 0.00% | +19,995 | New |
| Walleye Capital LLC | 20,204 | $462.7K | 0.00% | +20,204 | New |
| Lindbrook Capital, LLC | 21,000 | $480.9K | 0.04% | +21,000 | New |
| Manufacturers Life Insurance Company, The | 22,095 | $506.0K | 0.00% | +22,095 | New |
| Verition Fund Management LLC | 22,695 | $519.7K | 0.00% | +22,695 | New |
| Nuveen Asset Management, LLC | 23,961 | $548.7K | 0.00% | +23,961 | New |
| Jane Street Group, LLC | 26,208 | $600.2K | 0.00% | +26,208 | New |
| Barclays PLC | 28,785 | $659.2K | 0.00% | +28,785 | New |
| Alyeska Investment Group, L.P. | 35,000 | $801.5K | 0.00% | +35,000 | New |
| JPMorgan Chase & Co | 38,015 | $870.5K | 0.00% | +38,015 | New |
| Bank of New York Mellon Corp | 38,093 | $872.3K | 0.00% | +38,093 | New |
| Morgan Stanley | 41,911 | $959.8K | 0.00% | +41,911 | New |
| TD Asset Management Inc | 69,460 | $1.59M | 0.00% | +69,460 | New |
| Bank of America Corp | 78,744 | $1.80M | 0.00% | +78,744 | New |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 102,749 | $2.35M | 0.00% | +102,749 | New |
| UBS Group AG | 108,453 | $2.48M | 0.00% | +108,453 | New |
| Logos Global Management LP | 134,202 | $3.07M | 0.36% | +134,202 | New |
| Charles Schwab Investment Management Inc | 139,616 | $3.20M | 0.00% | +139,616 | New |
| Northern Trust Corp | 147,776 | $3.38M | 0.00% | +147,776 | New |
| ArrowMark Colorado Holdings LLC | 147,886 | $3.39M | 0.05% | +147,886 | New |
| Sio Capital Management, LLC | 271,687 | $6.22M | 1.75% | +271,687 | New |
| State Street Corp | 272,776 | $6.25M | 0.00% | +272,776 | New |
| Adage Capital Partners GP, L.L.C. | 300,000 | $6.87M | 0.01% | +300,000 | New |
| Woodline Partners LP | 300,000 | $6.87M | 0.05% | +300,000 | New |
| Geode Capital Management, LLC | 380,577 | $8.72M | 0.00% | +380,577 | New |
| Citadel Advisors LLC | 404,882 | $9.27M | 0.01% | +404,882 | New |
| Price T Rowe Associates Inc | 518,588 | $11.9M | 0.00% | +518,588 | New |
| Casdin Capital, LLC | 553,268 | $12.7M | 0.85% | +553,268 | New |
| Cormorant Asset Management, LP | 560,000 | $12.8M | 0.70% | +560,000 | New |
| Soleus Capital Management, L.P. | 675,409 | $15.5M | 1.17% | +675,409 | New |
| Perceptive Advisors LLC | 750,000 | $17.2M | 0.48% | +750,000 | New |
| Deerfield Management Company, L.P. (Series C) | 861,814 | $19.7M | 0.38% | +861,814 | New |
| Vanguard Group Inc | 985,032 | $22.6M | 0.00% | +985,032 | New |
| FMR LLC | 1,002,958 | $23.0M | 0.00% | +1,002,958 | New |
| Catalio Capital Management, LP | 1,024,245 | $23.5M | 5.13% | +1,024,245 | New |
| Janus Henderson Group PLC | 1,096,302 | $25.1M | 0.01% | +1,096,302 | New |
| Avoro Capital Advisors LLC | 1,110,000 | $25.4M | 0.36% | +1,110,000 | New |
| Goldman Sachs Group Inc | 1,674,357 | $38.3M | 0.01% | +1,674,357 | New |
| BlackRock, Inc. | 1,677,135 | $38.4M | 0.00% | +1,677,135 | New |
| Deep Track Capital, LP | 1,912,929 | $43.8M | 1.64% | +1,912,929 | New |
| Siren, L.L.C. | 2,202,514 | $50.4M | 2.23% | +2,202,514 | New |
| BVF Inc | 2,452,024 | $56.2M | 1.90% | +2,452,024 | New |
| Driehaus Capital Management LLC | 2,589,553 | $59.3M | 0.49% | +2,589,553 | New |
| Samsara BioCapital, LLC | 2,768,520 | $63.4M | 8.70% | +2,768,520 | New |
| TRV GP VI, LLC | 3,152,456 | $72.2M | 61.75% | +3,152,456 | New |
| TRV GP V, LLC | 6,215,591 | $142.3M | 48.42% | +6,215,591 | New |
| Ra Capital Management, L.P. | 6,995,858 | $160.2M | 2.13% | +6,995,858 | New |