Pyxis Oncology, Inc.
PYXS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001782223
In the last 90 days, Pyxis Oncology, Inc. insiders filed 0 open-market purchases and 1 sale; 76 institutions reported holding it in 13F filings for Q2 2026, worth $101.1M in total; no superinvestor holds it.
13F holders, Q2 2025
Institutional positions in Pyxis Oncology, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 74
- −15 vs. Q1 2025
- Shares held
- 27.5M
- −2.79M (−9.2%) vs. Q1 2025
- Total value
- $30.2M
- +$554.7K (+1.9%) vs. Q1 2025
- New holders
- 15
- 20 more added
- Sold out
- 30
- 24 more reduced
Compare with Q1 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PYXS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 76 | $101.1M |
| Q1 2026 | 78 | $40.5M |
| Q4 2025 | 79 | $34.7M |
| Q3 2025 | 73 | $59.7M |
| Q2 2025 | 74 | $30.2M |
| Q1 2025 | 89 | $29.6M |
| Q4 2024 | 99 | $49.2M |
| Q3 2024 | 92 | $102.3M |
| Q2 2024 | 80 | $93.1M |
| Q1 2024 | 71 | $97.7M |
| Q4 2023 | 51 | $15.8M |
| Q3 2023 | 54 | $15.4M |
| Q2 2023 | 48 | $24.6M |
| Q1 2023 | 47 | $41.5M |
| Q4 2022 | 31 | $26.5M |
| Q3 2022 | 38 | $38.3M |
| Q2 2022 | 39 | $47.7M |
| Q1 2022 | 45 | $76.1M |
| Q4 2021 | 51 | $199.9M |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q2 2025
Shares, value and share of portfolio for each institution holding Pyxis Oncology, Inc.; share changes are against Q1 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Pfizer Inc | 7,032,770 | $7.74M | 1.34% | 00.0% | Unchanged |
| Laurion Capital Management LP | 3,625,974 | $3.99M | 0.46% | 00.0% | Unchanged |
| Millennium Management LLC | 3,539,860 | $3.89M | 0.00% | +1,054,584+42.4% | Added |
| Tang Capital Management LLC | 2,500,000 | $2.75M | 0.14% | +1,400,000+127.3% | Added |
| Vanguard Group Inc | 2,149,396 | $2.36M | 0.00% | −287,332−11.8% | Reduced |
| Palo Alto Investors LP | 1,037,421 | $1.14M | 0.24% | 00.0% | Unchanged |
| BlackRock, Inc. | 926,805 | $1.02M | 0.00% | −2,345,169−71.7% | Reduced |
| Standard Life Aberdeen plc | 913,045 | $1.00M | 0.00% | 00.0% | Unchanged |
| 683 Capital Management, LLC | 545,000 | $599.5K | 0.06% | −5,000−0.9% | Reduced |
| Geode Capital Management, LLC | 510,963 | $562.3K | 0.00% | −598,135−53.9% | Reduced |
| Renaissance Technologies LLC | 417,822 | $459.6K | 0.00% | −164,314−28.2% | Reduced |
| UBS Group AG | 396,096 | $435.7K | 0.00% | −748−0.2% | Reduced |
| Pier 88 Investment Partners LLC | 367,170 | $403.9K | 0.08% | −23,790−6.1% | Reduced |
| Jane Street Group, LLC | 336,084 | $369.7K | 0.00% | +336,084 | New |
| Decheng Capital LLC | 326,810 | $359.5K | 0.09% | 00.0% | Unchanged |
| Schulhoff & Co Inc | 275,000 | $302.5K | 0.13% | +153,000+125.4% | Added |
| Goldman Sachs Group Inc | 224,274 | $246.7K | 0.00% | +63,444+39.4% | Added |
| State Street Corp | 186,055 | $204.7K | 0.00% | −746,143−80.0% | Reduced |
| Bank of New York Mellon Corp | 165,044 | $181.5K | 0.00% | −107,725−39.5% | Reduced |
| Morgan Stanley | 160,174 | $176.2K | 0.00% | −286,308−64.1% | Reduced |
| Marshall Wace, LLP | 147,771 | $162.5K | 0.00% | +147,771 | New |
| Bridgeway Capital Management, LLC | 142,295 | $156.5K | 0.00% | +61,500+76.1% | Added |
| Y-Intercept (Hong Kong) Ltd | 133,047 | $146.4K | 0.00% | +133,047 | New |
| Susquehanna International Group, LLP | 114,359 | $125.8K | 0.00% | +49,471+76.2% | Added |
| NewEdge Wealth, LLC | 116,006 | $124.1K | 0.00% | 00.0% | Unchanged |
| Qube Research & Technologies Ltd | 103,063 | $113.4K | 0.00% | +57,935+128.4% | Added |
| Northern Trust Corp | 102,216 | $112.4K | 0.00% | −271,500−72.6% | Reduced |
| FMR LLC | 94,846 | $104.3K | 0.00% | +8,191+9.5% | Added |
| AQR Capital Management LLC | 86,763 | $95.4K | 0.00% | +46,493+115.5% | Added |
| Royal Bank of Canada | 86,365 | $95.0K | 0.00% | −10,294−10.6% | Reduced |
| Cable Car Capital LLC | 61,606 | $67.8K | 0.03% | 00.0% | Unchanged |
| Commonwealth Equity Services, LLC | 61,155 | $67.0K | 0.00% | +17,905+41.4% | Added |
| HRT Financial LP | 50,668 | $55.0K | 0.00% | +50,668 | New |
| University of Chicago | 48,731 | $53.6K | 0.05% | 00.0% | Unchanged |
| Jain Global LLC | 48,649 | $53.5K | 0.00% | +48,649 | New |
| Velan Capital Investment Management LP | 40,000 | $44.0K | 0.04% | +40,000 | New |
| Dimensional Fund Advisors LP | 36,516 | $40.2K | 0.00% | 00.0% | Unchanged |
| XTX Topco Ltd | 36,380 | $40.0K | 0.00% | +36,380 | New |
| Squarepoint Ops LLC | 35,428 | $39.0K | 0.00% | +20,514+137.5% | Added |
| Cetera Investment Advisers | 28,760 | $31.6K | 0.00% | +900+3.2% | Added |
| Catalyst Funds Management Pty Ltd | 23,200 | $25.5K | 0.01% | +23,200 | New |
| Bank of America Corp | 22,069 | $24.3K | 0.00% | −18,254−45.3% | Reduced |
| Point72 Asia (Singapore) Pte. Ltd. | 19,228 | $21.2K | 0.00% | +19,228 | New |
| Acadian Asset Management LLC | 18,942 | $20.0K | 0.00% | −65,180−77.5% | Reduced |
| Advisor Group Holdings, Inc. | 17,721 | $19.5K | 0.00% | −4,658−20.8% | Reduced |
| Tower Research Capital LLC (TRC) | 14,657 | $16.1K | 0.00% | +3,499+31.4% | Added |
| LPL Financial LLC | 14,199 | $15.6K | 0.00% | −1,900−11.8% | Reduced |
| Hudson Bay Capital Management LP | 13,790 | $15.2K | 0.00% | +13,790 | New |
| DRW Securities, LLC | 13,042 | $14.3K | 0.00% | +13,042 | New |
| China Universal Asset Management Co., Ltd. | 12,442 | $13.7K | 0.00% | +514+4.3% | Added |
| Quadrature Capital Ltd | 12,334 | $13.6K | 0.00% | +12,334 | New |
| Simplex Trading, LLC | 12,615 | $13.0K | 0.00% | +3,810+43.3% | Added |
| Mercer Global Advisors Inc | 10,004 | $11.0K | 0.00% | +10,004 | New |
| Citigroup Inc | 8,927 | $9.82K | 0.00% | −26,113−74.5% | Reduced |
| Winthrop Capital Management, LLC | 6,000 | $7.00K | 0.00% | 00.0% | Unchanged |
| CWM, LLC | 6,536 | $7.00K | 0.00% | +3,150+93.0% | Added |
| Barclays PLC | 4,854 | $5.34K | 0.00% | −49,255−91.0% | Reduced |
| Raymond James Financial Inc | 3,231 | $3.55K | 0.00% | +3,231 | New |
| Mirae Asset Global Investments Co., Ltd. | 2,393 | $2.63K | 0.00% | +403+20.3% | Added |
| JPMorgan Chase & Co | 2,068 | $2.27K | 0.00% | −26,067−92.6% | Reduced |
| BNP Paribas Arbitrage, SA | 1,833 | $2.02K | 0.00% | −1,834−50.0% | Reduced |
| Jones Financial Companies LLLP | 1,500 | $1.65K | 0.00% | 00.0% | Unchanged |
| GF Fund Management Co. Ltd. | 1,429 | $1.57K | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 961 | $1.06K | 0.00% | +661+220.3% | Added |
| UMA Financial Services, Inc. | 943 | $1.04K | 0.00% | +943 | New |
| Wells Fargo & Company | 699 | $769 | 0.00% | −29,191−97.7% | Reduced |
| Group One Trading, L.P. | 602 | $662 | 0.00% | −2,408−80.0% | Reduced |
| EverSource Wealth Advisors, LLC | 591 | $650 | 0.00% | +107+22.1% | Added |
| True Wealth Design, LLC | 276 | $304 | 0.00% | +269+3,842.9% | Added |
| GWM Advisors LLC | 250 | $275 | 0.00% | 00.0% | Unchanged |
| Russell Investments Group, Ltd. | 64 | $70 | 0.00% | 00.0% | Unchanged |
| Northwestern Mutual Wealth Management Co | 12 | $13 | 0.00% | 00.0% | Unchanged |
| Caitong International Asset Management Co., Ltd | 1 | $1 | 0.00% | −2−66.7% | Reduced |
| SBI Securities Co., Ltd. | 1 | $1 | 0.00% | −1−50.0% | Reduced |
| Ikarian Capital, LLC | 0 | $0 | 0.00% | −613,253−100.0% | Sold out |
| Boothbay Fund Management, LLC | 0 | $0 | 0.00% | −181,042−100.0% | Sold out |
| Nuveen, LLC | 0 | $0 | 0.00% | −127,304−100.0% | Sold out |
| Charles Schwab Investment Management Inc | 0 | $0 | 0.00% | −115,237−100.0% | Sold out |
| Fan Yu | 0 | $0 | 0.00% | −69,303−100.0% | Sold out |
| Rhumbline Advisers | 0 | $0 | 0.00% | −68,156−100.0% | Sold out |
| SEI Investments Co | 0 | $0 | 0.00% | −61,140−100.0% | Sold out |
| Verition Fund Management LLC | 0 | $0 | 0.00% | −38,260−100.0% | Sold out |
| Intech Investment Management LLC | 0 | $0 | 0.00% | −32,173−100.0% | Sold out |
| Mirae Asset Global ETFs Holdings Ltd. | 0 | $0 | 0.00% | −29,259−100.0% | Sold out |
| Deutsche Bank AG | 0 | $0 | 0.00% | −28,390−100.0% | Sold out |
| American Century Companies Inc | 0 | $0 | 0.00% | −26,353−100.0% | Sold out |
| Invesco Ltd. | 0 | $0 | 0.00% | −24,805−100.0% | Sold out |
| Corebridge Financial, Inc. | 0 | $0 | 0.00% | −24,165−100.0% | Sold out |
| Price T Rowe Associates Inc | 0 | $0 | 0.00% | −22,220−100.0% | Sold out |
| Voya Investment Management LLC | 0 | $0 | 0.00% | −15,897−100.0% | Sold out |
| Alliancebernstein L.P. | 0 | $0 | 0.00% | −13,470−100.0% | Sold out |
| ProShare Advisors LLC | 0 | $0 | 0.00% | −13,361−100.0% | Sold out |
| JustInvest LLC | 0 | $0 | 0.00% | −12,987−100.0% | Sold out |
| CIBC World Markets Corp | 0 | $0 | 0.00% | −10,945−100.0% | Sold out |
| Police & Firemen's Retirement System of New Jersey | 0 | $0 | 0.00% | −9,818−100.0% | Sold out |
| Ameritas Investment Partners, Inc. | 0 | $0 | 0.00% | −4,784−100.0% | Sold out |
| Legal & General Group Plc | 0 | $0 | 0.00% | −4,219−100.0% | Sold out |
| California State Teachers Retirement System | 0 | $0 | 0.00% | −3,539−100.0% | Sold out |
| Federated Hermes, Inc. | 0 | $0 | 0.00% | −2,074−100.0% | Sold out |
| Amalgamated Bank | 0 | $0 | 0.00% | −1,690−100.0% | Sold out |