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Pyxis Oncology, Inc.

PYXS
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001782223

In the last 90 days, Pyxis Oncology, Inc. insiders filed 0 open-market purchases and 1 sale; 76 institutions reported holding it in 13F filings for Q2 2026, worth $101.1M in total; no superinvestor holds it.

13F holders, Q4 2023

Institutional positions in Pyxis Oncology, Inc. as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
51
−2 vs. Q3 2023
Shares held
8.80M
+1.31M (+17.5%) vs. Q3 2023
Total value
$15.8M
+$1.04M (+7.1%) vs. Q3 2023
New holders
9
9 more added
Sold out
11
12 more reduced

1 institution that held it in Q3 2023 haven't filed for Q4 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PYXS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2023: 51 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 51 institutionsQ1 2022: 45 institutionsQ2 2022: 39 institutionsQ3 2022: 38 institutionsQ4 2022: 31 institutionsQ1 2023: 47 institutionsQ2 2023: 48 institutionsQ3 2023: 54 institutionsQ4 2023: 51 institutionsQ1 2024: 71 institutionsQ2 2024: 80 institutionsQ3 2024: 92 institutionsQ4 2024: 99 institutionsQ1 2025: 89 institutionsQ2 2025: 74 institutionsQ3 2025: 73 institutionsQ4 2025: 79 institutionsQ1 2026: 78 institutionsQ2 2026: 76 institutions
Value heldQ4 2023: $15.8M
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $199.9MQ1 2022: $76.1MQ2 2022: $47.7MQ3 2022: $38.3MQ4 2022: $26.5MQ1 2023: $41.5MQ2 2023: $24.6MQ3 2023: $15.4MQ4 2023: $15.8MQ1 2024: $97.7MQ2 2024: $93.1MQ3 2024: $102.3MQ4 2024: $49.2MQ1 2025: $29.6MQ2 2025: $30.2MQ3 2025: $59.7MQ4 2025: $34.7MQ1 2026: $40.5MQ2 2026: $101.1M
Institutions holding PYXS and their total value by quarter
QuarterHoldersValue
Q2 202676$101.1M
Q1 202678$40.5M
Q4 202579$34.7M
Q3 202573$59.7M
Q2 202574$30.2M
Q1 202589$29.6M
Q4 202499$49.2M
Q3 202492$102.3M
Q2 202480$93.1M
Q1 202471$97.7M
Q4 202351$15.8M
Q3 202354$15.4M
Q2 202348$24.6M
Q1 202347$41.5M
Q4 202231$26.5M
Q3 202238$38.3M
Q2 202239$47.7M
Q1 202245$76.1M
Q4 202151$199.9M
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q4 2023

Shares, value and share of portfolio for each institution holding Pyxis Oncology, Inc.; share changes are against Q3 2023.

Institutions holding PYXS in Q4 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Laurion Capital Management LP3,170,803$5.71M0.20%00.0%Unchanged
Vanguard Group Inc1,306,685$2.35M0.00%+166,442+14.6%Added
Standard Life Aberdeen plc708,303$1.27M0.00%+708,303New
Vestal Point Capital, LP440,000$792.0K0.08%+440,000New
HHLR Advisors, Ltd.SuperinvestorHHLR Advisors (Hillhouse)382,606$688.7K0.01%00.0%Unchanged
Renaissance Technologies LLC364,150$655.0K0.00%+147,899+68.4%Added
Decheng Capital LLC326,810$588.3K0.16%+326,810New
BlackRock Inc.310,598$559.1K0.00%+9,084+3.0%Added
Geode Capital Management, LLC308,241$555.0K0.00%+19,942+6.9%Added
Bridgeway Capital Management, LLC236,195$425.2K0.01%00.0%Unchanged
Deutsche Bank AG125,000$225.0K0.00%00.0%Unchanged
Harvest Investment Services, LLC111,937$201.5K0.09%−1,957−1.7%Reduced
Citadel Advisors LLC106,835$192.3K0.00%+106,835New
Dimensional Fund Advisors LP101,810$183.3K0.00%−51,961−33.8%Reduced
Two Sigma Investments, LP91,563$164.8K0.00%−28,250−23.6%Reduced
State Street Corp83,055$149.5K0.00%00.0%Unchanged
Cornercap Investment Counsel Inc74,903$134.8K0.02%00.0%Unchanged
Fan Yu69,303$124.7K0.63%00.0%Unchanged
Two Sigma Advisers, LP64,200$115.6K0.00%−16,300−20.2%Reduced
Cable Car Capital LLC61,606$110.9K0.12%+61,606New
Northern Trust Corp60,283$108.5K0.00%+7,537+14.3%Added
University of Chicago48,731$87.7K0.12%00.0%Unchanged
Schulhoff & Co Inc22,000$39.6K0.02%00.0%Unchanged
XTX Topco Ltd20,559$37.0K0.01%+20,559New
Cetera Investment Advisers20,362$36.7K0.00%+1,102+5.7%Added
Bank of America Corp19,844$35.7K0.00%−81,010−80.3%Reduced
Bank of New York Mellon Corp16,134$29.0K0.00%+20.0%Added
Jane Street Group, LLC15,016$27.0K0.00%+15,016New
American Century Companies Inc13,771$24.8K0.00%00.0%Unchanged
Millennium Management LLC13,272$23.9K0.00%+13,272New
Commonwealth Equity Services, LLC12,950$23.0K0.00%00.0%Unchanged
Susquehanna International Group, LLP11,823$21.3K0.00%−20,730−63.7%Reduced
LPL Financial LLC11,429$20.6K0.00%+11,429New
Sawtooth Solutions, LLC11,234$20.2K0.00%00.0%Unchanged
Bleakley Financial Group, LLC11,234$20.2K0.00%00.0%Unchanged
Acadian Asset Management LLC11,278$20.0K0.00%−1,955−14.8%Reduced
Kingsview Wealth Management, LLC10,707$19.3K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)5,639$10.2K0.00%+3,656+184.4%Added
Morgan Stanley3,200$5.76K0.00%00.0%Unchanged
UBS Group AG2,955$5.32K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.2,636$4.74K0.00%−5,150−66.1%Reduced
Wells Fargo & Company2,531$4.56K0.00%+23+0.9%Added
Group One Trading, L.P.1,773$3.19K0.00%−1,297−42.2%Reduced
Royal Bank of Canada953$2.00K0.00%−2,320−70.9%Reduced
JPMorgan Chase & Co500$9000.00%00.0%Unchanged
GWM Advisors LLC250$4500.00%−1,542−86.0%Reduced
Allworth Financial LP200$3600.00%00.0%Unchanged
West Branch Capital LLC25$450.00%00.0%Unchanged
Qube Research & Technologies Ltd2$40.00%00.0%Unchanged
Gradient Investments LLC1$20.00%00.0%Unchanged
Coston, McIsaac & Partners30$00.00%−114−79.2%Reduced
ExodusPoint Capital Management, LP0$00.00%−415,072−100.0%Sold out
Squarepoint Ops LLC0$00.00%−22,556−100.0%Sold out
SG Americas Securities, LLC0$00.00%−19,996−100.0%Sold out
Cubist Systematic Strategies, LLC0$00.00%−13,312−100.0%Sold out
Prelude Capital Management, LLC0$00.00%−10,352−100.0%Sold out
Simplex Trading, LLC0$00.00%−1,402−100.0%Sold out
FMR LLC0$00.00%−346−100.0%Sold out
Authentikos Wealth Advisory, LLC0$00.00%−21−100.0%Sold out
Radcliffe Capital Management, L.P.0$00.00%−53,288−100.0%Sold out
Cutler Group LP0$00.00%−51−100.0%Sold out
CWM, LLC0$00.00%−92−100.0%Sold out
Decheng Capital Management III (Cayman), LLC––––Not filed