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Pyxis Oncology, Inc.

PYXS
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001782223

In the last 90 days, Pyxis Oncology, Inc. insiders filed 0 open-market purchases and 1 sale; 76 institutions reported holding it in 13F filings for Q2 2026, worth $101.1M in total; no superinvestor holds it.

13F holders, Q4 2024

Institutional positions in Pyxis Oncology, Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
99
+7 vs. Q3 2024
Shares held
31.6M
+3.67M (+13.2%) vs. Q3 2024
Total value
$49.2M
−$53.1M (−51.9%) vs. Q3 2024
New holders
25
33 more added
Sold out
18
19 more reduced

Compare with Q3 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PYXS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2024: 99 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 51 institutionsQ1 2022: 45 institutionsQ2 2022: 39 institutionsQ3 2022: 38 institutionsQ4 2022: 31 institutionsQ1 2023: 47 institutionsQ2 2023: 48 institutionsQ3 2023: 54 institutionsQ4 2023: 51 institutionsQ1 2024: 71 institutionsQ2 2024: 80 institutionsQ3 2024: 92 institutionsQ4 2024: 99 institutionsQ1 2025: 89 institutionsQ2 2025: 74 institutionsQ3 2025: 73 institutionsQ4 2025: 79 institutionsQ1 2026: 78 institutionsQ2 2026: 76 institutions
Value heldQ4 2024: $49.2M
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $199.9MQ1 2022: $76.1MQ2 2022: $47.7MQ3 2022: $38.3MQ4 2022: $26.5MQ1 2023: $41.5MQ2 2023: $24.6MQ3 2023: $15.4MQ4 2023: $15.8MQ1 2024: $97.7MQ2 2024: $93.1MQ3 2024: $102.3MQ4 2024: $49.2MQ1 2025: $29.6MQ2 2025: $30.2MQ3 2025: $59.7MQ4 2025: $34.7MQ1 2026: $40.5MQ2 2026: $101.1M
Institutions holding PYXS and their total value by quarter
QuarterHoldersValue
Q2 202676$101.1M
Q1 202678$40.5M
Q4 202579$34.7M
Q3 202573$59.7M
Q2 202574$30.2M
Q1 202589$29.6M
Q4 202499$49.2M
Q3 202492$102.3M
Q2 202480$93.1M
Q1 202471$97.7M
Q4 202351$15.8M
Q3 202354$15.4M
Q2 202348$24.6M
Q1 202347$41.5M
Q4 202231$26.5M
Q3 202238$38.3M
Q2 202239$47.7M
Q1 202245$76.1M
Q4 202151$199.9M
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q4 2024

Shares, value and share of portfolio for each institution holding Pyxis Oncology, Inc.; share changes are against Q3 2024.

Institutions holding PYXS in Q4 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Pfizer Inc7,032,770$11.0M0.42%+7,032,770New
Laurion Capital Management LP3,625,974$5.66M0.35%00.0%Unchanged
BlackRock, Inc.3,344,141$5.22M0.00%+379,981+12.8%Added
Millennium Management LLC2,980,906$4.65M0.00%+1,073,928+56.3%Added
Vanguard Group Inc2,441,153$3.81M0.00%+8,200+0.3%Added
Geode Capital Management, LLC1,082,449$1.69M0.00%−2,278−0.2%Reduced
Palo Alto Investors LP1,037,421$1.62M0.25%+867,421+510.2%Added
State Street Corp944,168$1.47M0.00%−7,083−0.7%Reduced
Standard Life Aberdeen plc913,045$1.42M0.00%00.0%Unchanged
Ikarian Capital, LLC613,253$956.7K0.27%−344,155−35.9%Reduced
Jacobs Levy Equity Management, Inc601,940$939.0K0.00%+219,100+57.2%Added
UBS Group AG446,699$696.9K0.00%+418,597+1,489.6%Added
683 Capital Management, LLC415,000$647.4K0.06%+344+0.1%Added
HHLR Advisors, Ltd.SuperinvestorHHLR Advisors (Hillhouse)382,606$596.9K0.02%00.0%Unchanged
Northern Trust Corp378,586$590.6K0.00%−15,449−3.9%Reduced
Ridgeback Capital Investments L.P.359,231$560.4K100.00%+359,231New
Decheng Capital LLC326,810$509.8K0.11%00.0%Unchanged
American Century Companies Inc299,937$467.9K0.00%+140,498+88.1%Added
Renaissance Technologies LLC293,354$457.6K0.00%+133,018+83.0%Added
Bank of New York Mellon Corp272,769$425.5K0.00%00.0%Unchanged
Bridgeway Capital Management, LLC269,995$421.2K0.01%+4,700+1.8%Added
Morgan Stanley242,731$378.7K0.00%+89,483+58.4%Added
Perceptive Advisors LLC188,462$294.0K0.01%−320,000−62.9%Reduced
Goldman Sachs Group Inc184,702$288.1K0.00%+45,570+32.8%Added
Boothbay Fund Management, LLC181,042$282.4K0.01%−102,574−36.2%Reduced
Marshall Wace, LLP157,953$246.4K0.00%+41,594+35.7%Added
UBS Oconnor LLC146,400$228.4K0.01%+146,400New
Charles Schwab Investment Management Inc129,761$202.4K0.00%00.0%Unchanged
Nuveen Asset Management, LLC127,304$198.6K0.00%−21,720−14.6%Reduced
Aristides Capital LLC124,000$193.4K0.06%+124,000New
Schulhoff & Co Inc122,000$190.3K0.08%00.0%Unchanged
NewEdge Wealth, LLC116,009$181.0K0.00%+30.0%Added
Dimensional Fund Advisors LP111,051$173.2K0.00%+29,105+35.5%Added
Pier 88 Investment Partners LLC98,590$153.8K0.03%−23,020−18.9%Reduced
State of Wisconsin Investment Board85,600$133.5K0.00%+85,600New
FMR LLC84,888$132.4K0.00%+80,916+2,037.2%Added
LMR Partners LLP77,300$120.6K0.00%−2,700−3.4%Reduced
Barclays PLC77,013$120.1K0.00%+12,924+20.2%Added
Fan Yu69,303$108.1K0.20%00.0%Unchanged
Susquehanna International Group, LLP67,975$106.0K0.00%−17,843−20.8%Reduced
Rhumbline Advisers67,851$105.8K0.00%+3,423+5.3%Added
Jane Street Group, LLC67,686$105.6K0.00%+18,128+36.6%Added
Cable Car Capital LLC61,606$96.1K0.01%00.0%Unchanged
SEI Investments Co61,140$95.4K0.00%+61,140New
Bank of America Corp53,745$83.8K0.00%+9,062+20.3%Added
AQR Capital Management LLC50,080$78.1K0.00%+50,080New
University of Chicago48,731$76.0K0.07%00.0%Unchanged
Citigroup Inc42,088$65.7K0.00%+6,513+18.3%Added
Deutsche Bank AG30,300$47.3K0.00%−208,090−87.3%Reduced
Graham Capital Management, L.P.30,287$47.2K0.00%+30,287New
Public Employees Retirement System of Ohio29,100$45.4K0.00%00.0%Unchanged
Wells Fargo & Company28,949$45.2K0.00%+4,724+19.5%Added
Royal Bank of Canada27,653$44.0K0.00%−7,673−21.7%Reduced
Mirae Asset Global ETFs Holdings Ltd.28,011$43.7K0.00%+1,216+4.5%Added
JPMorgan Chase & Co27,076$42.2K0.00%+5,099+23.2%Added
Cetera Investment Advisers26,860$41.9K0.00%+1,000+3.9%Added
Commonwealth Equity Services, LLC26,250$41.0K0.00%+10,000+61.5%Added
Invesco Ltd.25,366$39.6K0.00%+4,191+19.8%Added
Qube Research & Technologies Ltd24,524$38.3K0.00%−48,363−66.4%Reduced
Corebridge Financial, Inc.24,279$37.9K0.00%−1,833−7.0%Reduced
LPL Financial LLC22,599$35.3K0.00%+7,800+52.7%Added
XTX Topco Ltd22,492$35.1K0.00%−62,279−73.5%Reduced
Intech Investment Management LLC22,491$35.1K0.00%+7,594+51.0%Added
Advisor Group Holdings, Inc.22,379$34.9K0.00%+16,558+284.5%Added
Caption Management, LLC22,306$34.8K0.00%+22,306New
Ameriprise Financial Inc22,251$34.7K0.00%+22,251New
Two Sigma Investments, LP17,067$26.6K0.00%−7,515−30.6%Reduced
ProShare Advisors LLC16,568$25.8K0.00%+16,568New
Price T Rowe Associates Inc15,720$25.0K0.00%00.0%Unchanged
Voya Investment Management LLC15,897$24.8K0.00%−1,302−7.6%Reduced
Oxford Asset Management LLP14,438$22.5K0.01%+14,438New
Alliancebernstein L.P.13,470$21.0K0.00%00.0%Unchanged
Mariner, LLC12,863$20.1K0.00%+12,863New
China Universal Asset Management Co., Ltd.12,609$19.7K0.00%+12,609New
ADAR1 Capital Management, LLC10,000$15.6K0.00%00.0%Unchanged
Police & Firemen's Retirement System of New Jersey9,818$15.3K0.00%+9,818New
Tower Research Capital LLC (TRC)7,438$11.6K0.00%+3,283+79.0%Added
BNP Paribas Arbitrage, SA5,910$9.22K0.00%+5,910New
Winthrop Capital Management, LLC6,000$9.00K0.00%+6,000New
Ameritas Investment Partners, Inc.4,784$7.46K0.00%00.0%Unchanged
Legal & General Group Plc4,219$6.58K0.00%00.0%Unchanged
California State Teachers Retirement System3,539$5.52K0.00%00.0%Unchanged
Simplex Trading, LLC3,346$5.00K0.00%−25,124−88.2%Reduced
Mirae Asset Global Investments Co., Ltd.1,982$3.15K0.00%+1,982New
Amalgamated Bank1,690$3.00K0.00%00.0%Unchanged
Sterling Capital Management LLC1,659$2.59K0.00%+1,504+970.3%Added
Jones Financial Companies LLLP1,500$2.34K0.00%+1,000+200.0%Added
GF Fund Management Co. Ltd.1,249$1.95K0.00%+1,249New
R Squared Ltd880$1.37K0.00%+880New
New York State Common Retirement Fund600$9360.00%00.0%Unchanged
Caitong International Asset Management Co., Ltd327$5100.00%+327New
GWM Advisors LLC250$3900.00%00.0%Unchanged
Mainstream Capital Management LLC200$3120.00%+200New
Russell Investments Group, Ltd.64$1000.00%00.0%Unchanged
IFP Advisors, Inc17$270.00%+17New
Northwestern Mutual Wealth Management Co12$190.00%+12New
SBI Securities Co., Ltd.2$30.00%+2New
CWM, LLC246$00.00%−98−28.5%Reduced
Coston, McIsaac & Partners30$00.00%00.0%Unchanged
Deep Track Capital, LP0$00.00%−4,184,100−100.0%Sold out