Pyxis Oncology, Inc.
PYXS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001782223
In the last 90 days, Pyxis Oncology, Inc. insiders filed 0 open-market purchases and 1 sale; 76 institutions reported holding it in 13F filings for Q2 2026, worth $101.1M in total; no superinvestor holds it.
13F holders, Q2 2026
Institutional positions in Pyxis Oncology, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 76
- −1 vs. Q1 2026
- Shares held
- 34.2M
- +6.58M (+23.9%) vs. Q1 2026
- Total value
- $101.1M
- +$60.6M (+149.5%) vs. Q1 2026
- New holders
- 9
- 24 more added
- Sold out
- 10
- 24 more reduced
1 institution that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2026: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PYXS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 76 | $101.1M |
| Q1 2026 | 78 | $40.5M |
| Q4 2025 | 79 | $34.7M |
| Q3 2025 | 73 | $59.7M |
| Q2 2025 | 74 | $30.2M |
| Q1 2025 | 89 | $29.6M |
| Q4 2024 | 99 | $49.2M |
| Q3 2024 | 92 | $102.3M |
| Q2 2024 | 80 | $93.1M |
| Q1 2024 | 71 | $97.7M |
| Q4 2023 | 51 | $15.8M |
| Q3 2023 | 54 | $15.4M |
| Q2 2023 | 48 | $24.6M |
| Q1 2023 | 47 | $41.5M |
| Q4 2022 | 31 | $26.5M |
| Q3 2022 | 38 | $38.3M |
| Q2 2022 | 39 | $47.7M |
| Q1 2022 | 45 | $76.1M |
| Q4 2021 | 51 | $199.9M |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q2 2026
Shares, value and share of portfolio for each institution holding Pyxis Oncology, Inc.; share changes are against Q1 2026.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| GordonMD Global Investments LP | 10,024,909 | $30.2M | 16.57% | +5,903,039+143.2% | Added |
| Pfizer Inc | 7,032,770 | $19.5M | 11.43% | 00.0% | Unchanged |
| Laurion Capital Management LP | 4,900,888 | $14.8M | 1.07% | −96,445−1.9% | Reduced |
| Vanguard Capital Management LLC | 2,075,997 | $6.25M | 0.00% | +42,487+2.1% | Added |
| HealthInvest Partners AB | 966,459 | $2.91M | 0.78% | +769,423+390.5% | Added |
| BlackRock, Inc. | 867,934 | $2.61M | 0.00% | +79,095+10.0% | Added |
| Palo Alto Investors LP | 864,277 | $2.60M | 0.36% | −146,233−14.5% | Reduced |
| Marshall Wace, LLP | 830,544 | $2.50M | 0.00% | +476,127+134.3% | Added |
| Renaissance Technologies LLC | 772,232 | $2.32M | 0.00% | −116,448−13.1% | Reduced |
| Geode Capital Management, LLC | 591,849 | $1.78M | 0.00% | −6,272−1.0% | Reduced |
| Woodline Partners LP | 523,999 | $1.58M | 0.00% | +523,999 | New |
| 683 Capital Management, LLC | 459,367 | $1.38M | 0.13% | −436,896−48.7% | Reduced |
| Jacobs Levy Equity Management, Inc | 428,606 | $1.29M | 0.00% | −32,391−7.0% | Reduced |
| Longaeva Partners L.P. | 353,582 | $1.06M | 0.03% | −149,632−29.7% | Reduced |
| Decheng Capital LLC | 326,810 | $983.7K | 0.13% | 00.0% | Unchanged |
| Vanguard Fiduciary Trust Co | 302,986 | $912.0K | 0.00% | +2,089+0.7% | Added |
| Jane Street Group, LLC | 290,090 | $873.2K | 0.00% | −14,369−4.7% | Reduced |
| State Street Corp | 248,837 | $749.0K | 0.00% | 00.0% | Unchanged |
| Millennium Management LLC | 233,004 | $701.3K | 0.00% | −164,621−41.4% | Reduced |
| UBS Group AG | 155,217 | $467.2K | 0.00% | −98,907−38.9% | Reduced |
| Bank of New York Mellon Corp | 133,996 | $403.3K | 0.00% | 00.0% | Unchanged |
| Acadian Asset Management LLC | 126,793 | $380.0K | 0.00% | −17,463−12.1% | Reduced |
| Northern Trust Corp | 123,959 | $373.1K | 0.00% | +22,011+21.6% | Added |
| NewEdge Wealth, LLC | 116,006 | $349.2K | 0.00% | 00.0% | Unchanged |
| XTX Topco Ltd | 110,939 | $333.9K | 0.00% | −89,157−44.6% | Reduced |
| Two Sigma Investments, LP | 83,961 | $252.7K | 0.00% | +10,661+14.5% | Added |
| Bridgeway Capital Management, LLC | 81,260 | $244.6K | 0.00% | 00.0% | Unchanged |
| Bank of America Corp | 80,464 | $242.2K | 0.00% | +63,657+378.8% | Added |
| Stifel Financial Corp | 70,437 | $212.0K | 0.00% | +19,900+39.4% | Added |
| Cable Car Capital LLC | 61,606 | $185.4K | 0.00% | 00.0% | Unchanged |
| MYDA Advisors LLC | 50,000 | $150.5K | 0.04% | +50,000 | New |
| Qube Research & Technologies Ltd | 49,932 | $150.3K | 0.00% | +38,646+342.4% | Added |
| University of Chicago | 48,731 | $146.7K | 0.03% | 00.0% | Unchanged |
| Citadel Advisors LLC | 47,317 | $142.4K | 0.00% | −13,932−22.7% | Reduced |
| Quadrature Capital Ltd | 47,067 | $141.7K | 0.00% | +47,067 | New |
| Goldman Sachs Group Inc | 45,900 | $138.2K | 0.00% | −1,020−2.2% | Reduced |
| Verdad Advisers, LP | 44,899 | $135.1K | 0.13% | +44,899 | New |
| LPL Financial LLC | 43,554 | $131.1K | 0.00% | +10,000+29.8% | Added |
| Commonwealth Equity Services, LLC | 42,455 | $127.8K | 0.00% | +7,700+22.2% | Added |
| J. Derek Lewis & Associates Inc. | 42,000 | $126.4K | 0.02% | −1,000−2.3% | Reduced |
| Citigroup Inc | 38,205 | $115.0K | 0.00% | +36,465+2,095.7% | Added |
| Simplex Trading, LLC | 37,902 | $114.1K | 0.00% | +37,649+14,881.0% | Added |
| Point72 Asset Management, L.P. | 37,092 | $111.6K | 0.00% | +5,086+15.9% | Added |
| Walleye Capital LLC | 36,778 | $110.7K | 0.00% | +36,778 | New |
| Dimensional Fund Advisors LP | 36,175 | $108.9K | 0.00% | +10,263+39.6% | Added |
| Morgan Stanley | 33,448 | $100.7K | 0.00% | −36,240−52.0% | Reduced |
| Mackenzie Financial Corp | 26,343 | $79.3K | 0.00% | +26,343 | New |
| Cetera Investment Advisers | 25,000 | $75.3K | 0.00% | −2,260−8.3% | Reduced |
| Graham Capital Management, L.P. | 22,708 | $68.4K | 0.00% | −40−0.2% | Reduced |
| Vanguard Global Advisers, LLC | 21,242 | $63.9K | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 17,721 | $53.3K | 0.00% | +4,000+29.2% | Added |
| Group One Trading, L.P. | 16,480 | $49.6K | 0.00% | +16,480 | New |
| FMR LLC | 12,383 | $37.3K | 0.00% | +471+4.0% | Added |
| Paces Ferry Wealth Advisors, LLC | 11,440 | $34.4K | 0.01% | 00.0% | Unchanged |
| GWM Advisors LLC | 10,250 | $30.9K | 0.00% | 00.0% | Unchanged |
| China Universal Asset Management Co., Ltd. | 10,083 | $30.4K | 0.00% | −966−8.7% | Reduced |
| Tower Research Capital LLC (TRC) | 9,398 | $28.3K | 0.00% | −934−9.0% | Reduced |
| The PNC Financial Services Group, Inc. | 6,500 | $19.6K | 0.00% | 00.0% | Unchanged |
| Winthrop Capital Management, LLC | 6,000 | $18.0K | 0.00% | 00.0% | Unchanged |
| JPMorgan Chase & Co | 5,545 | $15.9K | 0.00% | +372+7.2% | Added |
| Hager Investment Management Services, LLC | 5,000 | $15.1K | 0.01% | 00.0% | Unchanged |
| Barclays PLC | 4,669 | $14.1K | 0.00% | −45,156−90.6% | Reduced |
| Federation des caisses Desjardins du Quebec | 4,500 | $13.5K | 0.00% | +4,500 | New |
| Federated Hermes, Inc. | 2,962 | $8.92K | 0.00% | −219−6.9% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 2,833 | $8.53K | 0.00% | −415−12.8% | Reduced |
| BNP Paribas Arbitrage, SA | 2,689 | $8.09K | 0.00% | +1,035+62.6% | Added |
| First United Bank Trust | 2,500 | $7.38K | 0.00% | +2,500 | New |
| GF Fund Management Co. Ltd. | 1,226 | $3.69K | 0.00% | −90−6.8% | Reduced |
| Nisa Investment Advisors, LLC | 961 | $2.89K | 0.00% | 00.0% | Unchanged |
| UMA Financial Services, Inc. | 943 | $2.84K | 0.00% | 00.0% | Unchanged |
| SBI Securities Co., Ltd. | 509 | $1.53K | 0.00% | +508+50,800.0% | Added |
| Jones Financial Companies LLLP | 500 | $1.39K | 0.00% | 00.0% | Unchanged |
| Wells Fargo & Company | 285 | $858 | 0.00% | 00.0% | Unchanged |
| Cornerstone Financial Management LLC | 172 | $518 | 0.00% | 00.0% | Unchanged |
| Caitong International Asset Management Co., Ltd | 35 | $105 | 0.00% | +31+775.0% | Added |
| SRS Capital Advisors, Inc. | 14 | $42 | 0.00% | +13+1,300.0% | Added |
| Panagora Asset Management Inc | 0 | $0 | 0.00% | −69,424−100.0% | Sold out |
| Toronto Dominion Bank | 0 | $0 | 0.00% | −50,000−100.0% | Sold out |
| Susquehanna International Group, LLP | 0 | $0 | 0.00% | −41,201−100.0% | Sold out |
| Maia Wealth LLC | 0 | $0 | 0.00% | −21,277−100.0% | Sold out |
| Catalyst Funds Management Pty Ltd | 0 | $0 | 0.00% | −20,400−100.0% | Sold out |
| Squarepoint Ops LLC | 0 | $0 | 0.00% | −17,537−100.0% | Sold out |
| Two Sigma Securities, LLC | 0 | $0 | 0.00% | −13,474−100.0% | Sold out |
| Royal Bank of Canada | 0 | $0 | 0.00% | −5,839−100.0% | Sold out |
| Balyasny Asset Management LLC | 0 | $0 | 0.00% | −743−100.0% | Sold out |
| Golden State Equity Partners | 0 | $0 | 0.00% | −10−100.0% | Sold out |
| CWM, LLC | – | – | – | – | Not filed |