Pyxis Oncology, Inc.
PYXS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001782223
In the last 90 days, Pyxis Oncology, Inc. insiders filed 0 open-market purchases and 1 sale; 76 institutions reported holding it in 13F filings for Q2 2026, worth $101.1M in total; no superinvestor holds it.
13F holders, Q2 2026
Institutional positions in Pyxis Oncology, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 76
- −1 vs. Q1 2026
- Shares held
- 34.2M
- +6.58M (+23.9%) vs. Q1 2026
- Total value
- $101.1M
- +$60.6M (+149.5%) vs. Q1 2026
- New holders
- 9
- 24 more added
- Sold out
- 10
- 24 more reduced
1 institution that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2026: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PYXS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 76 | $101.1M |
| Q1 2026 | 78 | $40.5M |
| Q4 2025 | 79 | $34.7M |
| Q3 2025 | 73 | $59.7M |
| Q2 2025 | 74 | $30.2M |
| Q1 2025 | 89 | $29.6M |
| Q4 2024 | 99 | $49.2M |
| Q3 2024 | 92 | $102.3M |
| Q2 2024 | 80 | $93.1M |
| Q1 2024 | 71 | $97.7M |
| Q4 2023 | 51 | $15.8M |
| Q3 2023 | 54 | $15.4M |
| Q2 2023 | 48 | $24.6M |
| Q1 2023 | 47 | $41.5M |
| Q4 2022 | 31 | $26.5M |
| Q3 2022 | 38 | $38.3M |
| Q2 2022 | 39 | $47.7M |
| Q1 2022 | 45 | $76.1M |
| Q4 2021 | 51 | $199.9M |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q2 2026
Shares, value and share of portfolio for each institution holding Pyxis Oncology, Inc.; share changes are against Q1 2026.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| SRS Capital Advisors, Inc. | 14 | $42 | 0.00% | +13+1,300.0% | Added |
| Caitong International Asset Management Co., Ltd | 35 | $105 | 0.00% | +31+775.0% | Added |
| Cornerstone Financial Management LLC | 172 | $518 | 0.00% | 00.0% | Unchanged |
| Wells Fargo & Company | 285 | $858 | 0.00% | 00.0% | Unchanged |
| Jones Financial Companies LLLP | 500 | $1.39K | 0.00% | 00.0% | Unchanged |
| SBI Securities Co., Ltd. | 509 | $1.53K | 0.00% | +508+50,800.0% | Added |
| UMA Financial Services, Inc. | 943 | $2.84K | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 961 | $2.89K | 0.00% | 00.0% | Unchanged |
| GF Fund Management Co. Ltd. | 1,226 | $3.69K | 0.00% | −90−6.8% | Reduced |
| First United Bank Trust | 2,500 | $7.38K | 0.00% | +2,500 | New |
| BNP Paribas Arbitrage, SA | 2,689 | $8.09K | 0.00% | +1,035+62.6% | Added |
| Mirae Asset Global Investments Co., Ltd. | 2,833 | $8.53K | 0.00% | −415−12.8% | Reduced |
| Federated Hermes, Inc. | 2,962 | $8.92K | 0.00% | −219−6.9% | Reduced |
| Federation des caisses Desjardins du Quebec | 4,500 | $13.5K | 0.00% | +4,500 | New |
| Barclays PLC | 4,669 | $14.1K | 0.00% | −45,156−90.6% | Reduced |
| Hager Investment Management Services, LLC | 5,000 | $15.1K | 0.01% | 00.0% | Unchanged |
| JPMorgan Chase & Co | 5,545 | $15.9K | 0.00% | +372+7.2% | Added |
| Winthrop Capital Management, LLC | 6,000 | $18.0K | 0.00% | 00.0% | Unchanged |
| The PNC Financial Services Group, Inc. | 6,500 | $19.6K | 0.00% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 9,398 | $28.3K | 0.00% | −934−9.0% | Reduced |
| China Universal Asset Management Co., Ltd. | 10,083 | $30.4K | 0.00% | −966−8.7% | Reduced |
| GWM Advisors LLC | 10,250 | $30.9K | 0.00% | 00.0% | Unchanged |
| Paces Ferry Wealth Advisors, LLC | 11,440 | $34.4K | 0.01% | 00.0% | Unchanged |
| FMR LLC | 12,383 | $37.3K | 0.00% | +471+4.0% | Added |
| Group One Trading, L.P. | 16,480 | $49.6K | 0.00% | +16,480 | New |
| Advisor Group Holdings, Inc. | 17,721 | $53.3K | 0.00% | +4,000+29.2% | Added |
| Vanguard Global Advisers, LLC | 21,242 | $63.9K | 0.00% | 00.0% | Unchanged |
| Graham Capital Management, L.P. | 22,708 | $68.4K | 0.00% | −40−0.2% | Reduced |
| Cetera Investment Advisers | 25,000 | $75.3K | 0.00% | −2,260−8.3% | Reduced |
| Mackenzie Financial Corp | 26,343 | $79.3K | 0.00% | +26,343 | New |
| Morgan Stanley | 33,448 | $100.7K | 0.00% | −36,240−52.0% | Reduced |
| Dimensional Fund Advisors LP | 36,175 | $108.9K | 0.00% | +10,263+39.6% | Added |
| Walleye Capital LLC | 36,778 | $110.7K | 0.00% | +36,778 | New |
| Point72 Asset Management, L.P. | 37,092 | $111.6K | 0.00% | +5,086+15.9% | Added |
| Simplex Trading, LLC | 37,902 | $114.1K | 0.00% | +37,649+14,881.0% | Added |
| Citigroup Inc | 38,205 | $115.0K | 0.00% | +36,465+2,095.7% | Added |
| J. Derek Lewis & Associates Inc. | 42,000 | $126.4K | 0.02% | −1,000−2.3% | Reduced |
| Commonwealth Equity Services, LLC | 42,455 | $127.8K | 0.00% | +7,700+22.2% | Added |
| LPL Financial LLC | 43,554 | $131.1K | 0.00% | +10,000+29.8% | Added |
| Verdad Advisers, LP | 44,899 | $135.1K | 0.13% | +44,899 | New |
| Goldman Sachs Group Inc | 45,900 | $138.2K | 0.00% | −1,020−2.2% | Reduced |
| Quadrature Capital Ltd | 47,067 | $141.7K | 0.00% | +47,067 | New |
| Citadel Advisors LLC | 47,317 | $142.4K | 0.00% | −13,932−22.7% | Reduced |
| University of Chicago | 48,731 | $146.7K | 0.03% | 00.0% | Unchanged |
| Qube Research & Technologies Ltd | 49,932 | $150.3K | 0.00% | +38,646+342.4% | Added |
| MYDA Advisors LLC | 50,000 | $150.5K | 0.04% | +50,000 | New |
| Cable Car Capital LLC | 61,606 | $185.4K | 0.00% | 00.0% | Unchanged |
| Stifel Financial Corp | 70,437 | $212.0K | 0.00% | +19,900+39.4% | Added |
| Bank of America Corp | 80,464 | $242.2K | 0.00% | +63,657+378.8% | Added |
| Bridgeway Capital Management, LLC | 81,260 | $244.6K | 0.00% | 00.0% | Unchanged |
| Two Sigma Investments, LP | 83,961 | $252.7K | 0.00% | +10,661+14.5% | Added |
| XTX Topco Ltd | 110,939 | $333.9K | 0.00% | −89,157−44.6% | Reduced |
| NewEdge Wealth, LLC | 116,006 | $349.2K | 0.00% | 00.0% | Unchanged |
| Northern Trust Corp | 123,959 | $373.1K | 0.00% | +22,011+21.6% | Added |
| Acadian Asset Management LLC | 126,793 | $380.0K | 0.00% | −17,463−12.1% | Reduced |
| Bank of New York Mellon Corp | 133,996 | $403.3K | 0.00% | 00.0% | Unchanged |
| UBS Group AG | 155,217 | $467.2K | 0.00% | −98,907−38.9% | Reduced |
| Millennium Management LLC | 233,004 | $701.3K | 0.00% | −164,621−41.4% | Reduced |
| State Street Corp | 248,837 | $749.0K | 0.00% | 00.0% | Unchanged |
| Jane Street Group, LLC | 290,090 | $873.2K | 0.00% | −14,369−4.7% | Reduced |
| Vanguard Fiduciary Trust Co | 302,986 | $912.0K | 0.00% | +2,089+0.7% | Added |
| Decheng Capital LLC | 326,810 | $983.7K | 0.13% | 00.0% | Unchanged |
| Longaeva Partners L.P. | 353,582 | $1.06M | 0.03% | −149,632−29.7% | Reduced |
| Jacobs Levy Equity Management, Inc | 428,606 | $1.29M | 0.00% | −32,391−7.0% | Reduced |
| 683 Capital Management, LLC | 459,367 | $1.38M | 0.13% | −436,896−48.7% | Reduced |
| Woodline Partners LP | 523,999 | $1.58M | 0.00% | +523,999 | New |
| Geode Capital Management, LLC | 591,849 | $1.78M | 0.00% | −6,272−1.0% | Reduced |
| Renaissance Technologies LLC | 772,232 | $2.32M | 0.00% | −116,448−13.1% | Reduced |
| Marshall Wace, LLP | 830,544 | $2.50M | 0.00% | +476,127+134.3% | Added |
| Palo Alto Investors LP | 864,277 | $2.60M | 0.36% | −146,233−14.5% | Reduced |
| BlackRock, Inc. | 867,934 | $2.61M | 0.00% | +79,095+10.0% | Added |
| HealthInvest Partners AB | 966,459 | $2.91M | 0.78% | +769,423+390.5% | Added |
| Vanguard Capital Management LLC | 2,075,997 | $6.25M | 0.00% | +42,487+2.1% | Added |
| Laurion Capital Management LP | 4,900,888 | $14.8M | 1.07% | −96,445−1.9% | Reduced |
| Pfizer Inc | 7,032,770 | $19.5M | 11.43% | 00.0% | Unchanged |
| GordonMD Global Investments LP | 10,024,909 | $30.2M | 16.57% | +5,903,039+143.2% | Added |
| Panagora Asset Management Inc | 0 | $0 | 0.00% | −69,424−100.0% | Sold out |
| Toronto Dominion Bank | 0 | $0 | 0.00% | −50,000−100.0% | Sold out |
| Susquehanna International Group, LLP | 0 | $0 | 0.00% | −41,201−100.0% | Sold out |
| Maia Wealth LLC | 0 | $0 | 0.00% | −21,277−100.0% | Sold out |
| Catalyst Funds Management Pty Ltd | 0 | $0 | 0.00% | −20,400−100.0% | Sold out |
| Squarepoint Ops LLC | 0 | $0 | 0.00% | −17,537−100.0% | Sold out |
| Two Sigma Securities, LLC | 0 | $0 | 0.00% | −13,474−100.0% | Sold out |
| Royal Bank of Canada | 0 | $0 | 0.00% | −5,839−100.0% | Sold out |
| Balyasny Asset Management LLC | 0 | $0 | 0.00% | −743−100.0% | Sold out |
| Golden State Equity Partners | 0 | $0 | 0.00% | −10−100.0% | Sold out |
| CWM, LLC | – | – | – | – | Not filed |