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Pyxis Oncology, Inc.

PYXS
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001782223

In the last 90 days, Pyxis Oncology, Inc. insiders filed 0 open-market purchases and 1 sale; 76 institutions reported holding it in 13F filings for Q2 2026, worth $101.1M in total; no superinvestor holds it.

13F holders, Q1 2025

Institutional positions in Pyxis Oncology, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
89
−9 vs. Q4 2024
Shares held
30.3M
−1.18M (−3.7%) vs. Q4 2024
Total value
$29.6M
−$19.4M (−39.5%) vs. Q4 2024
New holders
13
21 more added
Sold out
22
26 more reduced

1 institution that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PYXS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 89 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 51 institutionsQ1 2022: 45 institutionsQ2 2022: 39 institutionsQ3 2022: 38 institutionsQ4 2022: 31 institutionsQ1 2023: 47 institutionsQ2 2023: 48 institutionsQ3 2023: 54 institutionsQ4 2023: 51 institutionsQ1 2024: 71 institutionsQ2 2024: 80 institutionsQ3 2024: 92 institutionsQ4 2024: 99 institutionsQ1 2025: 89 institutionsQ2 2025: 74 institutionsQ3 2025: 73 institutionsQ4 2025: 79 institutionsQ1 2026: 78 institutionsQ2 2026: 76 institutions
Value heldQ1 2025: $29.6M
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $199.9MQ1 2022: $76.1MQ2 2022: $47.7MQ3 2022: $38.3MQ4 2022: $26.5MQ1 2023: $41.5MQ2 2023: $24.6MQ3 2023: $15.4MQ4 2023: $15.8MQ1 2024: $97.7MQ2 2024: $93.1MQ3 2024: $102.3MQ4 2024: $49.2MQ1 2025: $29.6MQ2 2025: $30.2MQ3 2025: $59.7MQ4 2025: $34.7MQ1 2026: $40.5MQ2 2026: $101.1M
Institutions holding PYXS and their total value by quarter
QuarterHoldersValue
Q2 202676$101.1M
Q1 202678$40.5M
Q4 202579$34.7M
Q3 202573$59.7M
Q2 202574$30.2M
Q1 202589$29.6M
Q4 202499$49.2M
Q3 202492$102.3M
Q2 202480$93.1M
Q1 202471$97.7M
Q4 202351$15.8M
Q3 202354$15.4M
Q2 202348$24.6M
Q1 202347$41.5M
Q4 202231$26.5M
Q3 202238$38.3M
Q2 202239$47.7M
Q1 202245$76.1M
Q4 202151$199.9M
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding Pyxis Oncology, Inc.; share changes are against Q4 2024.

Institutions holding PYXS in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Pfizer Inc7,032,770$6.89M1.38%00.0%Unchanged
Laurion Capital Management LP3,625,974$3.55M0.27%00.0%Unchanged
BlackRock, Inc.3,271,974$3.21M0.00%−72,167−2.2%Reduced
Millennium Management LLC2,485,276$2.44M0.00%−495,630−16.6%Reduced
Vanguard Group Inc2,436,728$2.39M0.00%−4,425−0.2%Reduced
Geode Capital Management, LLC1,109,098$1.09M0.00%+26,649+2.5%Added
Tang Capital Management LLC1,100,000$1.08M0.06%+1,100,000New
Palo Alto Investors LP1,037,421$1.02M0.19%00.0%Unchanged
State Street Corp932,198$913.5K0.00%−11,970−1.3%Reduced
Standard Life Aberdeen plc913,045$894.7K0.00%00.0%Unchanged
Ikarian Capital, LLC613,253$600.9K0.20%00.0%Unchanged
Renaissance Technologies LLC582,136$570.4K0.00%+288,782+98.4%Added
683 Capital Management, LLC550,000$538.9K0.05%+135,000+32.5%Added
Morgan Stanley446,482$437.5K0.00%+203,751+83.9%Added
UBS Group AG396,844$388.9K0.00%−49,855−11.2%Reduced
Pier 88 Investment Partners LLC390,960$383.1K0.07%+292,370+296.6%Added
Northern Trust Corp373,716$366.2K0.00%−4,870−1.3%Reduced
Decheng Capital LLC326,810$320.2K0.09%00.0%Unchanged
Bank of New York Mellon Corp272,769$267.3K0.00%00.0%Unchanged
Boothbay Fund Management, LLC181,042$177.4K0.01%00.0%Unchanged
Goldman Sachs Group Inc160,830$157.6K0.00%−23,872−12.9%Reduced
Nuveen, LLC127,304$124.7K0.00%+127,304New
Schulhoff & Co Inc122,000$119.5K0.05%00.0%Unchanged
NewEdge Wealth, LLC116,006$113.7K0.00%−30.0%Reduced
Charles Schwab Investment Management Inc115,237$112.9K0.00%−14,524−11.2%Reduced
Royal Bank of Canada96,659$95.0K0.00%+69,006+249.5%Added
FMR LLC86,655$84.9K0.00%+1,767+2.1%Added
Acadian Asset Management LLC84,122$81.0K0.00%+84,122New
Bridgeway Capital Management, LLC80,795$79.2K0.00%−189,200−70.1%Reduced
Fan Yu69,303$67.9K0.07%00.0%Unchanged
Rhumbline Advisers68,156$66.8K0.00%+305+0.4%Added
Susquehanna International Group, LLP64,888$63.6K0.00%−3,087−4.5%Reduced
Cable Car Capital LLC61,606$60.4K0.07%00.0%Unchanged
SEI Investments Co61,140$59.9K0.00%00.0%Unchanged
Barclays PLC54,109$53.0K0.00%−22,904−29.7%Reduced
University of Chicago48,731$47.8K0.07%00.0%Unchanged
Qube Research & Technologies Ltd45,128$44.2K0.00%+20,604+84.0%Added
Commonwealth Equity Services, LLC43,250$42.0K0.00%+17,000+64.8%Added
Bank of America Corp40,323$39.5K0.00%−13,422−25.0%Reduced
AQR Capital Management LLC40,270$39.5K0.00%−9,810−19.6%Reduced
Verition Fund Management LLC38,260$37.5K0.00%+38,260New
Dimensional Fund Advisors LP36,516$35.8K0.00%−74,535−67.1%Reduced
Citigroup Inc35,040$34.3K0.00%−7,048−16.7%Reduced
Intech Investment Management LLC32,173$31.5K0.00%+9,682+43.0%Added
Wells Fargo & Company29,890$29.3K0.00%+941+3.3%Added
Mirae Asset Global ETFs Holdings Ltd.29,259$28.7K0.00%+1,248+4.5%Added
Deutsche Bank AG28,390$27.8K0.00%−1,910−6.3%Reduced
JPMorgan Chase & Co28,135$27.6K0.00%+1,059+3.9%Added
Cetera Investment Advisers27,860$27.3K0.00%+1,000+3.7%Added
American Century Companies Inc26,353$25.8K0.00%−273,584−91.2%Reduced
Invesco Ltd.24,805$24.3K0.00%−561−2.2%Reduced
Corebridge Financial, Inc.24,165$23.7K0.00%−114−0.5%Reduced
Price T Rowe Associates Inc22,220$23.0K0.00%+6,500+41.3%Added
Advisor Group Holdings, Inc.22,379$21.9K0.00%00.0%Unchanged
LPL Financial LLC16,099$15.8K0.00%−6,500−28.8%Reduced
Voya Investment Management LLC15,897$15.6K0.00%00.0%Unchanged
Squarepoint Ops LLC14,914$14.6K0.00%+14,914New
Alliancebernstein L.P.13,470$13.2K0.00%00.0%Unchanged
ProShare Advisors LLC13,361$13.1K0.00%−3,207−19.4%Reduced
JustInvest LLC12,987$12.7K0.00%+12,987New
China Universal Asset Management Co., Ltd.11,928$11.7K0.00%−681−5.4%Reduced
Tower Research Capital LLC (TRC)11,158$10.9K0.00%+3,720+50.0%Added
CIBC World Markets Corp10,945$10.7K0.00%+10,945New
Police & Firemen's Retirement System of New Jersey9,818$9.62K0.00%00.0%Unchanged
Simplex Trading, LLC8,805$8.00K0.00%+5,459+163.2%Added
Winthrop Capital Management, LLC6,000$6.00K0.00%00.0%Unchanged
Ameritas Investment Partners, Inc.4,784$4.69K0.00%00.0%Unchanged
Legal & General Group Plc4,219$4.13K0.00%00.0%Unchanged
BNP Paribas Arbitrage, SA3,667$3.59K0.00%−2,243−38.0%Reduced
California State Teachers Retirement System3,539$3.47K0.00%00.0%Unchanged
CWM, LLC3,386$3.00K0.00%+3,140+1,276.4%Added
Group One Trading, L.P.3,010$2.95K0.00%+3,010New
Mirae Asset Global Investments Co., Ltd.1,990$2.11K0.00%+8+0.4%Added
Federated Hermes, Inc.2,074$2.03K0.00%+2,074New
Amalgamated Bank1,690$2.00K0.00%00.0%Unchanged
Jones Financial Companies LLLP1,500$1.59K0.00%00.0%Unchanged
GF Fund Management Co. Ltd.1,429$1.40K0.00%+180+14.4%Added
Affinity Wealth LLC1,400$1.37K0.00%+1,400New
Sterling Capital Management LLC877$8590.00%−782−47.1%Reduced
New York State Common Retirement Fund600$5880.00%00.0%Unchanged
EverSource Wealth Advisors, LLC484$4740.00%+484New
Nisa Investment Advisors, LLC300$2940.00%+300New
GWM Advisors LLC250$2450.00%00.0%Unchanged
Russell Investments Group, Ltd.64$630.00%00.0%Unchanged
IFP Advisors, Inc17$170.00%00.0%Unchanged
Northwestern Mutual Wealth Management Co12$120.00%00.0%Unchanged
True Wealth Design, LLC7$70.00%+7New
Caitong International Asset Management Co., Ltd3$30.00%−324−99.1%Reduced
SBI Securities Co., Ltd.2$20.00%00.0%Unchanged
Jacobs Levy Equity Management, Inc0$00.00%−601,940−100.0%Sold out
HHLR Advisors, Ltd.SuperinvestorHHLR Advisors (Hillhouse)0$00.00%−382,606−100.0%Sold out
Ridgeback Capital Investments L.P.0$00.00%−359,231−100.0%Sold out
Perceptive Advisors LLC0$00.00%−188,462−100.0%Sold out
Marshall Wace, LLP0$00.00%−157,953−100.0%Sold out
UBS Oconnor LLC0$00.00%−146,400−100.0%Sold out
Aristides Capital LLC0$00.00%−124,000−100.0%Sold out
State of Wisconsin Investment Board0$00.00%−85,600−100.0%Sold out
LMR Partners LLP0$00.00%−77,300−100.0%Sold out
Jane Street Group, LLC0$00.00%−67,686−100.0%Sold out
Graham Capital Management, L.P.0$00.00%−30,287−100.0%Sold out