Pyxis Oncology, Inc.
PYXS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001782223
In the last 90 days, Pyxis Oncology, Inc. insiders filed 0 open-market purchases and 1 sale; 76 institutions reported holding it in 13F filings for Q2 2026, worth $101.1M in total; no superinvestor holds it.
13F holders, Q2 2025
Institutional positions in Pyxis Oncology, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 74
- −15 vs. Q1 2025
- Shares held
- 27.5M
- −2.79M (−9.2%) vs. Q1 2025
- Total value
- $30.2M
- +$554.7K (+1.9%) vs. Q1 2025
- New holders
- 15
- 20 more added
- Sold out
- 30
- 24 more reduced
Compare with Q1 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PYXS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 76 | $101.1M |
| Q1 2026 | 78 | $40.5M |
| Q4 2025 | 79 | $34.7M |
| Q3 2025 | 73 | $59.7M |
| Q2 2025 | 74 | $30.2M |
| Q1 2025 | 89 | $29.6M |
| Q4 2024 | 99 | $49.2M |
| Q3 2024 | 92 | $102.3M |
| Q2 2024 | 80 | $93.1M |
| Q1 2024 | 71 | $97.7M |
| Q4 2023 | 51 | $15.8M |
| Q3 2023 | 54 | $15.4M |
| Q2 2023 | 48 | $24.6M |
| Q1 2023 | 47 | $41.5M |
| Q4 2022 | 31 | $26.5M |
| Q3 2022 | 38 | $38.3M |
| Q2 2022 | 39 | $47.7M |
| Q1 2022 | 45 | $76.1M |
| Q4 2021 | 51 | $199.9M |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q2 2025
Shares, value and share of portfolio for each institution holding Pyxis Oncology, Inc.; share changes are against Q1 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Caitong International Asset Management Co., Ltd | 1 | $1 | 0.00% | −2−66.7% | Reduced |
| SBI Securities Co., Ltd. | 1 | $1 | 0.00% | −1−50.0% | Reduced |
| Northwestern Mutual Wealth Management Co | 12 | $13 | 0.00% | 00.0% | Unchanged |
| Russell Investments Group, Ltd. | 64 | $70 | 0.00% | 00.0% | Unchanged |
| GWM Advisors LLC | 250 | $275 | 0.00% | 00.0% | Unchanged |
| True Wealth Design, LLC | 276 | $304 | 0.00% | +269+3,842.9% | Added |
| EverSource Wealth Advisors, LLC | 591 | $650 | 0.00% | +107+22.1% | Added |
| Group One Trading, L.P. | 602 | $662 | 0.00% | −2,408−80.0% | Reduced |
| Wells Fargo & Company | 699 | $769 | 0.00% | −29,191−97.7% | Reduced |
| UMA Financial Services, Inc. | 943 | $1.04K | 0.00% | +943 | New |
| Nisa Investment Advisors, LLC | 961 | $1.06K | 0.00% | +661+220.3% | Added |
| GF Fund Management Co. Ltd. | 1,429 | $1.57K | 0.00% | 00.0% | Unchanged |
| Jones Financial Companies LLLP | 1,500 | $1.65K | 0.00% | 00.0% | Unchanged |
| BNP Paribas Arbitrage, SA | 1,833 | $2.02K | 0.00% | −1,834−50.0% | Reduced |
| JPMorgan Chase & Co | 2,068 | $2.27K | 0.00% | −26,067−92.6% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 2,393 | $2.63K | 0.00% | +403+20.3% | Added |
| Raymond James Financial Inc | 3,231 | $3.55K | 0.00% | +3,231 | New |
| Barclays PLC | 4,854 | $5.34K | 0.00% | −49,255−91.0% | Reduced |
| Winthrop Capital Management, LLC | 6,000 | $7.00K | 0.00% | 00.0% | Unchanged |
| CWM, LLC | 6,536 | $7.00K | 0.00% | +3,150+93.0% | Added |
| Citigroup Inc | 8,927 | $9.82K | 0.00% | −26,113−74.5% | Reduced |
| Mercer Global Advisors Inc | 10,004 | $11.0K | 0.00% | +10,004 | New |
| Simplex Trading, LLC | 12,615 | $13.0K | 0.00% | +3,810+43.3% | Added |
| Quadrature Capital Ltd | 12,334 | $13.6K | 0.00% | +12,334 | New |
| China Universal Asset Management Co., Ltd. | 12,442 | $13.7K | 0.00% | +514+4.3% | Added |
| DRW Securities, LLC | 13,042 | $14.3K | 0.00% | +13,042 | New |
| Hudson Bay Capital Management LP | 13,790 | $15.2K | 0.00% | +13,790 | New |
| LPL Financial LLC | 14,199 | $15.6K | 0.00% | −1,900−11.8% | Reduced |
| Tower Research Capital LLC (TRC) | 14,657 | $16.1K | 0.00% | +3,499+31.4% | Added |
| Advisor Group Holdings, Inc. | 17,721 | $19.5K | 0.00% | −4,658−20.8% | Reduced |
| Acadian Asset Management LLC | 18,942 | $20.0K | 0.00% | −65,180−77.5% | Reduced |
| Point72 Asia (Singapore) Pte. Ltd. | 19,228 | $21.2K | 0.00% | +19,228 | New |
| Bank of America Corp | 22,069 | $24.3K | 0.00% | −18,254−45.3% | Reduced |
| Catalyst Funds Management Pty Ltd | 23,200 | $25.5K | 0.01% | +23,200 | New |
| Cetera Investment Advisers | 28,760 | $31.6K | 0.00% | +900+3.2% | Added |
| Squarepoint Ops LLC | 35,428 | $39.0K | 0.00% | +20,514+137.5% | Added |
| XTX Topco Ltd | 36,380 | $40.0K | 0.00% | +36,380 | New |
| Dimensional Fund Advisors LP | 36,516 | $40.2K | 0.00% | 00.0% | Unchanged |
| Velan Capital Investment Management LP | 40,000 | $44.0K | 0.04% | +40,000 | New |
| Jain Global LLC | 48,649 | $53.5K | 0.00% | +48,649 | New |
| University of Chicago | 48,731 | $53.6K | 0.05% | 00.0% | Unchanged |
| HRT Financial LP | 50,668 | $55.0K | 0.00% | +50,668 | New |
| Commonwealth Equity Services, LLC | 61,155 | $67.0K | 0.00% | +17,905+41.4% | Added |
| Cable Car Capital LLC | 61,606 | $67.8K | 0.03% | 00.0% | Unchanged |
| Royal Bank of Canada | 86,365 | $95.0K | 0.00% | −10,294−10.6% | Reduced |
| AQR Capital Management LLC | 86,763 | $95.4K | 0.00% | +46,493+115.5% | Added |
| FMR LLC | 94,846 | $104.3K | 0.00% | +8,191+9.5% | Added |
| Northern Trust Corp | 102,216 | $112.4K | 0.00% | −271,500−72.6% | Reduced |
| Qube Research & Technologies Ltd | 103,063 | $113.4K | 0.00% | +57,935+128.4% | Added |
| NewEdge Wealth, LLC | 116,006 | $124.1K | 0.00% | 00.0% | Unchanged |
| Susquehanna International Group, LLP | 114,359 | $125.8K | 0.00% | +49,471+76.2% | Added |
| Y-Intercept (Hong Kong) Ltd | 133,047 | $146.4K | 0.00% | +133,047 | New |
| Bridgeway Capital Management, LLC | 142,295 | $156.5K | 0.00% | +61,500+76.1% | Added |
| Marshall Wace, LLP | 147,771 | $162.5K | 0.00% | +147,771 | New |
| Morgan Stanley | 160,174 | $176.2K | 0.00% | −286,308−64.1% | Reduced |
| Bank of New York Mellon Corp | 165,044 | $181.5K | 0.00% | −107,725−39.5% | Reduced |
| State Street Corp | 186,055 | $204.7K | 0.00% | −746,143−80.0% | Reduced |
| Goldman Sachs Group Inc | 224,274 | $246.7K | 0.00% | +63,444+39.4% | Added |
| Schulhoff & Co Inc | 275,000 | $302.5K | 0.13% | +153,000+125.4% | Added |
| Decheng Capital LLC | 326,810 | $359.5K | 0.09% | 00.0% | Unchanged |
| Jane Street Group, LLC | 336,084 | $369.7K | 0.00% | +336,084 | New |
| Pier 88 Investment Partners LLC | 367,170 | $403.9K | 0.08% | −23,790−6.1% | Reduced |
| UBS Group AG | 396,096 | $435.7K | 0.00% | −748−0.2% | Reduced |
| Renaissance Technologies LLC | 417,822 | $459.6K | 0.00% | −164,314−28.2% | Reduced |
| Geode Capital Management, LLC | 510,963 | $562.3K | 0.00% | −598,135−53.9% | Reduced |
| 683 Capital Management, LLC | 545,000 | $599.5K | 0.06% | −5,000−0.9% | Reduced |
| Standard Life Aberdeen plc | 913,045 | $1.00M | 0.00% | 00.0% | Unchanged |
| BlackRock, Inc. | 926,805 | $1.02M | 0.00% | −2,345,169−71.7% | Reduced |
| Palo Alto Investors LP | 1,037,421 | $1.14M | 0.24% | 00.0% | Unchanged |
| Vanguard Group Inc | 2,149,396 | $2.36M | 0.00% | −287,332−11.8% | Reduced |
| Tang Capital Management LLC | 2,500,000 | $2.75M | 0.14% | +1,400,000+127.3% | Added |
| Millennium Management LLC | 3,539,860 | $3.89M | 0.00% | +1,054,584+42.4% | Added |
| Laurion Capital Management LP | 3,625,974 | $3.99M | 0.46% | 00.0% | Unchanged |
| Pfizer Inc | 7,032,770 | $7.74M | 1.34% | 00.0% | Unchanged |
| Ikarian Capital, LLC | 0 | $0 | 0.00% | −613,253−100.0% | Sold out |
| Boothbay Fund Management, LLC | 0 | $0 | 0.00% | −181,042−100.0% | Sold out |
| Nuveen, LLC | 0 | $0 | 0.00% | −127,304−100.0% | Sold out |
| Charles Schwab Investment Management Inc | 0 | $0 | 0.00% | −115,237−100.0% | Sold out |
| Fan Yu | 0 | $0 | 0.00% | −69,303−100.0% | Sold out |
| Rhumbline Advisers | 0 | $0 | 0.00% | −68,156−100.0% | Sold out |
| SEI Investments Co | 0 | $0 | 0.00% | −61,140−100.0% | Sold out |
| Verition Fund Management LLC | 0 | $0 | 0.00% | −38,260−100.0% | Sold out |
| Intech Investment Management LLC | 0 | $0 | 0.00% | −32,173−100.0% | Sold out |
| Mirae Asset Global ETFs Holdings Ltd. | 0 | $0 | 0.00% | −29,259−100.0% | Sold out |
| Deutsche Bank AG | 0 | $0 | 0.00% | −28,390−100.0% | Sold out |
| American Century Companies Inc | 0 | $0 | 0.00% | −26,353−100.0% | Sold out |
| Invesco Ltd. | 0 | $0 | 0.00% | −24,805−100.0% | Sold out |
| Corebridge Financial, Inc. | 0 | $0 | 0.00% | −24,165−100.0% | Sold out |
| Price T Rowe Associates Inc | 0 | $0 | 0.00% | −22,220−100.0% | Sold out |
| Voya Investment Management LLC | 0 | $0 | 0.00% | −15,897−100.0% | Sold out |
| Alliancebernstein L.P. | 0 | $0 | 0.00% | −13,470−100.0% | Sold out |
| ProShare Advisors LLC | 0 | $0 | 0.00% | −13,361−100.0% | Sold out |
| JustInvest LLC | 0 | $0 | 0.00% | −12,987−100.0% | Sold out |
| CIBC World Markets Corp | 0 | $0 | 0.00% | −10,945−100.0% | Sold out |
| Police & Firemen's Retirement System of New Jersey | 0 | $0 | 0.00% | −9,818−100.0% | Sold out |
| Ameritas Investment Partners, Inc. | 0 | $0 | 0.00% | −4,784−100.0% | Sold out |
| Legal & General Group Plc | 0 | $0 | 0.00% | −4,219−100.0% | Sold out |
| California State Teachers Retirement System | 0 | $0 | 0.00% | −3,539−100.0% | Sold out |
| Federated Hermes, Inc. | 0 | $0 | 0.00% | −2,074−100.0% | Sold out |
| Amalgamated Bank | 0 | $0 | 0.00% | −1,690−100.0% | Sold out |