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Puma Biotechnology, Inc.

PBYI
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001401667

In the last 90 days, Puma Biotechnology, Inc. insiders filed 0 open-market purchases and 5 sales; 160 institutions reported holding it in 13F filings for Q2 2026, worth $313.6M in total; no superinvestor holds it.

13F holders, Q2 2026

Institutional positions in Puma Biotechnology, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
160
+6 vs. Q1 2026
Shares held
38.7M
+835.0K (+2.2%) vs. Q1 2026
Total value
$313.6M
+$71.9M (+29.8%) vs. Q1 2026
New holders
21
60 more added
Sold out
15
52 more reduced

3 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PBYI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 160 institutions
Q1 2021: 118 institutionsQ2 2021: 120 institutionsQ3 2021: 116 institutionsQ4 2021: 102 institutionsQ1 2022: 104 institutionsQ2 2022: 89 institutionsQ3 2022: 83 institutionsQ4 2022: 89 institutionsQ1 2023: 78 institutionsQ2 2023: 68 institutionsQ3 2023: 69 institutionsQ4 2023: 82 institutionsQ1 2024: 93 institutionsQ2 2024: 99 institutionsQ3 2024: 100 institutionsQ4 2024: 112 institutionsQ1 2025: 116 institutionsQ2 2025: 121 institutionsQ3 2025: 132 institutionsQ4 2025: 151 institutionsQ1 2026: 157 institutionsQ2 2026: 160 institutions
Value heldQ2 2026: $313.6M
Q1 2021: $355.9MQ2 2021: $319.3MQ3 2021: $226.0MQ4 2021: $93.1MQ1 2022: $86.1MQ2 2022: $79.5MQ3 2022: $65.5MQ4 2022: $116.3MQ1 2023: $86.3MQ2 2023: $93.8MQ3 2023: $67.6MQ4 2023: $117.0MQ1 2024: $164.4MQ2 2024: $101.0MQ3 2024: $76.0MQ4 2024: $90.1MQ1 2025: $90.1MQ2 2025: $112.8MQ3 2025: $182.6MQ4 2025: $210.2MQ1 2026: $241.8MQ2 2026: $313.6M
Institutions holding PBYI and their total value by quarter
QuarterHoldersValue
Q2 2026160$313.6M
Q1 2026157$241.8M
Q4 2025151$210.2M
Q3 2025132$182.6M
Q2 2025121$112.8M
Q1 2025116$90.1M
Q4 2024112$90.1M
Q3 2024100$76.0M
Q2 202499$101.0M
Q1 202493$164.4M
Q4 202382$117.0M
Q3 202369$67.6M
Q2 202368$93.8M
Q1 202378$86.3M
Q4 202289$116.3M
Q3 202283$65.5M
Q2 202289$79.5M
Q1 2022104$86.1M
Q4 2021102$93.1M
Q3 2021116$226.0M
Q2 2021120$319.3M
Q1 2021118$355.9M

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Puma Biotechnology, Inc.; share changes are against Q1 2026.

Institutions holding PBYI in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Winton Group Ltd40,509$328.5K0.01%−25,824−38.9%Reduced
Man Group plc41,506$336.6K0.00%−5,869−12.4%Reduced
Deutsche Bank AG43,192$350.3K0.00%+10,047+30.3%Added
Vanguard Global Advisers, LLC46,267$375.2K0.00%+17,094+58.6%Added
D'Orazio & Associates, Inc.48,680$394.8K0.05%−1,235−2.5%Reduced
Rhumbline Advisers57,510$466.4K0.00%+4,474+8.4%Added
OpenArc Corporate Advisory, LLC59,491$482.5K0.01%−30,000−33.5%Reduced
Nomura Asset Management International Inc.61,255$497.0K0.00%00.0%Unchanged
Vise Technologies, Inc.72,030$584.2K0.01%+31,732+78.7%Added
Trexquant Investment LP72,223$585.7K0.00%+72,223New
Canada Pension Plan Investment Board73,500$596.1K0.00%+50,700+222.4%Added
Evergreen Capital Management LLC73,731$598.0K0.01%−22,269−23.2%Reduced
Nuveen, LLC82,298$667.4K0.00%+3,197+4.0%Added
STRS Ohio84,600$686.1K0.00%−6,900−7.5%Reduced
Wellington Management Group LLP126,091$1.02M0.00%+126,091New
Charles Schwab Investment Management Inc128,243$1.04M0.00%+12,328+10.6%Added
Round Rock Advisors, LLC128,912$1.05M0.13%00.0%Unchanged
First Trust Advisors LP130,206$1.06M0.00%+6,693+5.4%Added
Two Sigma Investments, LP140,587$1.14M0.00%+127,587+981.4%Added
Haven Private, LLC148,448$1.20M0.46%−6,812−4.4%Reduced
Prospera Financial Services Inc158,762$1.29M0.02%−14,289−8.3%Reduced
Franklin Resources Inc172,010$1.40M0.00%−43,381−20.1%Reduced
State of Wisconsin Investment Board188,232$1.53M0.00%−20,386−9.8%Reduced
FMR LLC211,444$1.71M0.00%+19,611+10.2%Added
JPMorgan Chase & Co211,339$1.73M0.00%−9,385−4.3%Reduced
Prudential Financial Inc213,599$1.73M0.00%−39,440−15.6%Reduced
Panagora Asset Management Inc217,545$1.76M0.01%+22,658+11.6%Added
Empowered Funds, LLC220,316$1.79M0.01%+16,275+8.0%Added
Federated Hermes, Inc.250,766$2.03M0.00%+13,051+5.5%Added
Morgan Stanley265,670$2.15M0.00%−94,072−26.1%Reduced
Vanguard Fiduciary Trust Co269,070$2.18M0.00%+17,387+6.9%Added
Russell Investments Group, Ltd.272,234$2.21M0.00%+20,581+8.2%Added
Invesco Ltd.301,002$2.44M0.00%+205,958+216.7%Added
State Board of Administration of Florida Retirement System309,106$2.51M0.00%+36,216+13.3%Added
D. E. Shaw & Co., Inc.316,343$2.57M0.00%−34,892−9.9%Reduced
Bank of New York Mellon Corp360,734$2.93M0.00%+12,853+3.7%Added
Globeflex Capital L P382,807$3.10M0.40%+33,156+9.5%Added
SEI Investments Co418,669$3.40M0.00%−89,513−17.6%Reduced
Arrowstreet Capital, Limited Partnership532,450$4.32M0.00%−5,705−1.1%Reduced
Millennium Management LLC602,240$4.88M0.00%−875,279−59.2%Reduced
UBS Group AG636,761$5.16M0.00%+102,534+19.2%Added
Connor, Clark & Lunn Investment Management Ltd.642,946$5.21M0.01%−139,852−17.9%Reduced
Northern Trust Corp652,386$5.29M0.00%+10,633+1.7%Added
Goldman Sachs Group Inc669,156$5.43M0.00%−563−0.1%Reduced
AQR Capital Management LLC725,192$5.88M0.00%−75,002−9.4%Reduced
Ritholtz Wealth Management749,798$6.08M0.09%−24,510−3.2%Reduced
Bridgeway Capital Management, LLC791,616$6.42M0.11%+16,275+2.1%Added
Kennedy Capital Management, Inc.873,253$7.08M0.13%−16,348−1.8%Reduced
State Street Corp952,165$7.72M0.00%+34,575+3.8%Added
O'Shaughnessy Asset Management, LLC1,123,783$9.11M0.04%−14,386−1.3%Reduced
Geode Capital Management, LLC1,339,405$10.9M0.00%+322,063+31.7%Added
Dimensional Fund Advisors LP1,518,014$12.3M0.00%+81,908+5.7%Added
LSV Asset Management1,617,981$13.1M0.02%+435,113+36.8%Added
Vanguard Portfolio Management LLC1,825,599$14.8M0.00%+90,950+5.2%Added
Vanguard Capital Management LLC1,835,643$14.9M0.00%+17,962+1.0%Added
Renaissance Technologies LLC1,836,213$14.9M0.02%−106,200−5.5%Reduced
Acadian Asset Management LLC2,053,523$16.6M0.02%+11,764+0.6%Added
American Century Companies Inc2,319,996$18.8M0.01%+403,650+21.1%Added
BlackRock, Inc.3,804,736$30.9M0.00%+205,784+5.7%Added
Acorn Capital Advisors, LLC4,131,299$33.5M9.14%00.0%Unchanged
Citadel Advisors LLC0$00.00%−29,959−100.0%Sold out
Virtus ETF Advisers LLC0$00.00%−29,347−100.0%Sold out
Engineers Gate Manager LP0$00.00%−28,600−100.0%Sold out
Lazard Asset Management LLC0$00.00%−17,970−100.0%Sold out
Quadrature Capital Ltd0$00.00%−16,745−100.0%Sold out
Ashton Thomas Private Wealth, LLC0$00.00%−13,500−100.0%Sold out
HRT Financial LP0$00.00%−13,073−100.0%Sold out
Cambridge Investment Research Advisors, Inc.0$00.00%−12,563−100.0%Sold out
Abacus Wealth Partners, LLC0$00.00%−11,199−100.0%Sold out
Stokes Family Office, LLC0$00.00%−10,092−100.0%Sold out
MAI Capital Management0$00.00%−7,558−100.0%Sold out
Intentional Wealth Strategies, LLC0$00.00%−1,128−100.0%Sold out
Root Financial Partners, LLC0$00.00%−269−100.0%Sold out
Frazier Financial Advisors, LLC0$00.00%−183−100.0%Sold out
Wealth Preservation Advisors, LLC0$00.00%−1−100.0%Sold out
CWM, LLC––––Not filed
DGS Capital Management, LLC––––Not filed
Sunbelt Securities, Inc.––––Not filed