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Puma Biotechnology, Inc.

PBYI
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001401667

In the last 90 days, Puma Biotechnology, Inc. insiders filed 0 open-market purchases and 5 sales; 160 institutions reported holding it in 13F filings for Q2 2026, worth $313.6M in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Puma Biotechnology, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
132
+11 vs. Q2 2025
Shares held
34.4M
+1.57M (+4.8%) vs. Q2 2025
Total value
$182.5M
+$70.0M (+62.2%) vs. Q2 2025
New holders
23
43 more added
Sold out
12
36 more reduced

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PBYI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 132 institutions
Q1 2021: 118 institutionsQ2 2021: 120 institutionsQ3 2021: 116 institutionsQ4 2021: 102 institutionsQ1 2022: 104 institutionsQ2 2022: 89 institutionsQ3 2022: 83 institutionsQ4 2022: 89 institutionsQ1 2023: 78 institutionsQ2 2023: 68 institutionsQ3 2023: 69 institutionsQ4 2023: 82 institutionsQ1 2024: 93 institutionsQ2 2024: 99 institutionsQ3 2024: 100 institutionsQ4 2024: 112 institutionsQ1 2025: 116 institutionsQ2 2025: 121 institutionsQ3 2025: 132 institutionsQ4 2025: 151 institutionsQ1 2026: 157 institutionsQ2 2026: 160 institutions
Value heldQ3 2025: $182.5M
Q1 2021: $355.9MQ2 2021: $319.3MQ3 2021: $226.0MQ4 2021: $92.2MQ1 2022: $86.1MQ2 2022: $79.5MQ3 2022: $65.5MQ4 2022: $116.3MQ1 2023: $86.1MQ2 2023: $93.8MQ3 2023: $67.6MQ4 2023: $115.2MQ1 2024: $157.7MQ2 2024: $100.9MQ3 2024: $75.9MQ4 2024: $89.7MQ1 2025: $90.0MQ2 2025: $112.5MQ3 2025: $182.5MQ4 2025: $210.2MQ1 2026: $241.8MQ2 2026: $313.6M
Institutions holding PBYI and their total value by quarter
QuarterHoldersValue
Q2 2026160$313.6M
Q1 2026157$241.8M
Q4 2025151$210.2M
Q3 2025132$182.5M
Q2 2025121$112.5M
Q1 2025116$90.0M
Q4 2024112$89.7M
Q3 2024100$75.9M
Q2 202499$100.9M
Q1 202493$157.7M
Q4 202382$115.2M
Q3 202369$67.6M
Q2 202368$93.8M
Q1 202378$86.1M
Q4 202289$116.3M
Q3 202283$65.5M
Q2 202289$79.5M
Q1 2022104$86.1M
Q4 2021102$92.2M
Q3 2021116$226.0M
Q2 2021120$319.3M
Q1 2021118$355.9M

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Puma Biotechnology, Inc.; share changes are against Q2 2025.

Institutions holding PBYI in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Private Wealth Asset Management, LLC3,500$18.6K0.00%00.0%Unchanged
Ball & Co Wealth Management Inc.3,066$16.0K0.01%−440−12.5%Reduced
California State Teachers Retirement System3,001$15.9K0.00%+2+0.1%Added
Sterling Capital Management LLC2,927$15.5K0.00%+1,782+155.6%Added
Royal Bank of Canada1,708$9.00K0.00%−74,927−97.8%Reduced
Amalgamated Bank1,432$8.00K0.00%00.0%Unchanged
Global Retirement Partners, LLC1,492$7.92K0.00%00.0%Unchanged
Rialto Wealth Management, LLC1,450$7.70K0.00%00.0%Unchanged
SRS Capital Advisors, Inc.1,272$6.75K0.00%+1,272New
GHP Investment Advisors, Inc.1,170$6.21K0.00%00.0%Unchanged
WealthCollab, LLC1,156$6.14K0.00%00.0%Unchanged
GPS Wealth Strategies Group, LLC1,000$5.31K0.00%00.0%Unchanged
Citigroup Inc859$4.56K0.00%−13,461−94.0%Reduced
CIBC Private Wealth Group, LLC775$4.12K0.00%00.0%Unchanged
Optiver Holding B.V.768$4.08K0.00%+768New
Essential Partners LLC439$2.33K0.00%00.0%Unchanged
Nisa Investment Advisors, LLC342$1.82K0.00%00.0%Unchanged
Clearstead Advisors, LLC335$1.78K0.00%00.0%Unchanged
Rothschild Investment LLC250$1.33K0.00%+250New
Luminist Capital LLC250$1.32K0.00%00.0%Unchanged
US Bancorp200$1.06K0.00%00.0%Unchanged
EverSource Wealth Advisors, LLC167$8870.00%+6+3.7%Added
Atlantic Union Bankshares Corp150$7970.00%+150New
True Wealth Design, LLC123$6540.00%−4−3.1%Reduced
The PNC Financial Services Group, Inc.117$6210.00%+117New
GAMMA Investing LLC78$4140.00%+78New
Jones Financial Companies LLLP68$3290.00%+68New
SBI Securities Co., Ltd.56$2970.00%00.0%Unchanged
IFP Advisors, Inc49$2600.00%+9+22.5%Added
Sunbelt Securities, Inc.30$1590.00%+30New
Allworth Financial LP5$270.00%+4+400.0%Added
ZRC Wealth Management, LLC3$160.00%00.0%Unchanged
Janus Henderson Group PLC0$00.00%−745,541−100.0%Sold out
Citadel Advisors LLC0$00.00%−507,818−100.0%Sold out
Eversept Partners, LP0$00.00%−240,688−100.0%Sold out
State Board of Administration of Florida Retirement System0$00.00%−71,727−100.0%Sold out
Kapitalo Investimentos Ltda0$00.00%−70,269−100.0%Sold out
Susquehanna International Group, LLP0$00.00%−57,724−100.0%Sold out
HSBC Holdings PLC0$00.00%−19,751−100.0%Sold out
Ieq Capital, LLC0$00.00%−14,305−100.0%Sold out
Voya Investment Management LLC0$00.00%−12,976−100.0%Sold out
Williams & Novak, LLC0$00.00%−12,520−100.0%Sold out
Fourth Dimension Wealth, LLC0$00.00%−500−100.0%Sold out
South State Corp.0$00.00%−111−100.0%Sold out