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Puma Biotechnology, Inc.

PBYI
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001401667

In the last 90 days, Puma Biotechnology, Inc. insiders filed 0 open-market purchases and 5 sales; 160 institutions reported holding it in 13F filings for Q2 2026, worth $313.6M in total; no superinvestor holds it.

13F holders, Q1 2025

Institutional positions in Puma Biotechnology, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
116
+5 vs. Q4 2024
Shares held
30.4M
+953.1K (+3.2%) vs. Q4 2024
Total value
$90.1M
+$170.3K (+0.2%) vs. Q4 2024
New holders
25
44 more added
Sold out
20
25 more reduced

1 institution that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PBYI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 116 institutions
Q1 2021: 118 institutionsQ2 2021: 120 institutionsQ3 2021: 116 institutionsQ4 2021: 102 institutionsQ1 2022: 104 institutionsQ2 2022: 89 institutionsQ3 2022: 83 institutionsQ4 2022: 89 institutionsQ1 2023: 78 institutionsQ2 2023: 68 institutionsQ3 2023: 69 institutionsQ4 2023: 82 institutionsQ1 2024: 93 institutionsQ2 2024: 99 institutionsQ3 2024: 100 institutionsQ4 2024: 112 institutionsQ1 2025: 116 institutionsQ2 2025: 121 institutionsQ3 2025: 132 institutionsQ4 2025: 151 institutionsQ1 2026: 157 institutionsQ2 2026: 160 institutions
Value heldQ1 2025: $90.1M
Q1 2021: $355.9MQ2 2021: $319.3MQ3 2021: $226.0MQ4 2021: $93.1MQ1 2022: $86.1MQ2 2022: $79.5MQ3 2022: $65.5MQ4 2022: $116.3MQ1 2023: $86.3MQ2 2023: $93.8MQ3 2023: $67.6MQ4 2023: $117.0MQ1 2024: $164.4MQ2 2024: $101.0MQ3 2024: $76.0MQ4 2024: $90.1MQ1 2025: $90.1MQ2 2025: $112.8MQ3 2025: $182.6MQ4 2025: $210.2MQ1 2026: $241.8MQ2 2026: $313.6M
Institutions holding PBYI and their total value by quarter
QuarterHoldersValue
Q2 2026160$313.6M
Q1 2026157$241.8M
Q4 2025151$210.2M
Q3 2025132$182.6M
Q2 2025121$112.8M
Q1 2025116$90.1M
Q4 2024112$90.1M
Q3 2024100$76.0M
Q2 202499$101.0M
Q1 202493$164.4M
Q4 202382$117.0M
Q3 202369$67.6M
Q2 202368$93.8M
Q1 202378$86.3M
Q4 202289$116.3M
Q3 202283$65.5M
Q2 202289$79.5M
Q1 2022104$86.1M
Q4 2021102$93.1M
Q3 2021116$226.0M
Q2 2021120$319.3M
Q1 2021118$355.9M

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding Puma Biotechnology, Inc.; share changes are against Q4 2024.

Institutions holding PBYI in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Arrowstreet Capital, Limited Partnership358,621$1.06M0.00%+358,621New
Los Angeles Capital Management LLC406,854$1.20M0.01%+121,175+42.4%Added
Globeflex Capital L P452,606$1.34M0.12%00.0%Unchanged
D. E. Shaw & Co., Inc.571,665$1.69M0.00%+349,057+156.8%Added
State Street Corp649,792$1.92M0.00%+39,850+6.5%Added
Connor, Clark & Lunn Investment Management Ltd.831,689$2.46M0.01%+344,321+70.6%Added
Dimensional Fund Advisors LP888,663$2.63M0.00%+24,903+2.9%Added
Kennedy Capital Management, Inc.911,123$2.70M0.06%+101,748+12.6%Added
Geode Capital Management, LLC955,456$2.83M0.00%+36,021+3.9%Added
American Century Companies Inc1,149,660$3.40M0.00%+201,284+21.2%Added
Millennium Management LLC1,385,194$4.10M0.00%−508,932−26.9%Reduced
Renaissance Technologies LLC1,829,213$5.41M0.01%+73,700+4.2%Added
Acadian Asset Management LLC2,008,146$5.94M0.02%+36,018+1.8%Added
Vanguard Group Inc3,669,263$10.9M0.00%+25,841+0.7%Added
BlackRock, Inc.3,847,368$11.4M0.00%+23,563+0.6%Added
Acorn Capital Advisors, LLC3,940,052$11.7M7.78%00.0%Unchanged
Citadel Advisors LLC0$00.00%−159,425−100.0%Sold out
Squarepoint Ops LLC0$00.00%−75,929−100.0%Sold out
Panagora Asset Management Inc0$00.00%−58,849−100.0%Sold out
Winton Group Ltd0$00.00%−38,241−100.0%Sold out
Schonfeld Strategic Advisors LLC0$00.00%−35,300−100.0%Sold out
Cubist Systematic Strategies, LLC0$00.00%−32,615−100.0%Sold out
SG Americas Securities, LLC0$00.00%−24,668−100.0%Sold out
Jane Street Group, LLC0$00.00%−22,480−100.0%Sold out
State of Wyoming0$00.00%−20,426−100.0%Sold out
Ritholtz Wealth Management0$00.00%−20,128−100.0%Sold out
Bayesian Capital Management, LP0$00.00%−17,700−100.0%Sold out
Jain Global LLC0$00.00%−11,871−100.0%Sold out
ProShare Advisors LLC0$00.00%−11,853−100.0%Sold out
PDT Partners, LLC0$00.00%−11,131−100.0%Sold out
Verition Fund Management LLC0$00.00%−10,955−100.0%Sold out
Advantage Alpha Capital Partners LP0$00.00%−6,796−100.0%Sold out
R Squared Ltd0$00.00%−5,020−100.0%Sold out
Caitong International Asset Management Co., Ltd0$00.00%−133−100.0%Sold out
Aventura Private Wealth, LLC0$00.00%−100−100.0%Sold out
Richards, Merrill & Peterson, Inc.0$00.00%−40−100.0%Sold out
Nuveen Asset Management, LLC––––Not filed