Structure Therapeutics Inc.
GPCR- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001888886
No open-market purchases or sales by Structure Therapeutics Inc. insiders were filed in the last 90 days; 191 institutions reported holding it in 13F filings for Q2 2026, worth $3.62B in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Structure Therapeutics Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 198
- +1 vs. Q4 2025
- Shares held
- 66.8M
- +1.94M (+3.0%) vs. Q4 2025
- Total value
- $3.23B
- −$1.29B (−28.6%) vs. Q4 2025
- New holders
- 41
- 72 more added
- Sold out
- 40
- 58 more reduced
2 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting GPCR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 191 | $3.62B |
| Q1 2026 | 198 | $3.23B |
| Q4 2025 | 199 | $4.58B |
| Q3 2025 | 158 | $1.59B |
| Q2 2025 | 173 | $1.14B |
| Q1 2025 | 151 | $990.0M |
| Q4 2024 | 165 | $1.65B |
| Q3 2024 | 161 | $2.69B |
| Q2 2024 | 167 | $2.33B |
| Q1 2024 | 119 | $1.86B |
| Q4 2023 | 122 | $1.74B |
| Q3 2023 | 84 | $1.64B |
| Q2 2023 | 48 | $699.4M |
| Q1 2023 | 38 | $346.2M |
| Q4 2022 | 0 | $0 |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Structure Therapeutics Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| EcoR1 Capital, LLC | 0 | $0 | 0.00% | −334,380−100.0% | Sold out |
| Capricorn Fund Managers Ltd | 0 | $0 | 0.00% | −252,600−100.0% | Sold out |
| Jane Street Group, LLC | 0 | $0 | 0.00% | −147,217−100.0% | Sold out |
| Alyeska Investment Group, L.P. | 0 | $0 | 0.00% | −115,000−100.0% | Sold out |
| RTW Investments, LP | 0 | $0 | 0.00% | −100,000−100.0% | Sold out |
| Susquehanna Fundamental Investments, LLC | 0 | $0 | 0.00% | −99,617−100.0% | Sold out |
| SummitTX Capital, L.P. | 0 | $0 | 0.00% | −94,671−100.0% | Sold out |
| Simplex Trading, LLC | 0 | $0 | 0.00% | −92,668−100.0% | Sold out |
| Longaeva Partners L.P. | 0 | $0 | 0.00% | −60,000−100.0% | Sold out |
| Integral Health Asset Management, LLC | 0 | $0 | 0.00% | −50,000−100.0% | Sold out |
| ACT Capital Management, LLC | 0 | $0 | 0.00% | −38,500−100.0% | Sold out |
| EAM Investors, LLC | 0 | $0 | 0.00% | −38,054−100.0% | Sold out |
| Vestal Point Capital, LP | 0 | $0 | 0.00% | −35,000−100.0% | Sold out |
| Maven Securities LTD | 0 | $0 | 0.00% | −20,000−100.0% | Sold out |
| Acadian Asset Management LLC | 0 | $0 | 0.00% | −17,606−100.0% | Sold out |
| J. Goldman & Co LP | 0 | $0 | 0.00% | −13,601−100.0% | Sold out |
| Quadrature Capital Ltd | 0 | $0 | 0.00% | −12,761−100.0% | Sold out |
| Y-Intercept (Hong Kong) Ltd | 0 | $0 | 0.00% | −10,132−100.0% | Sold out |
| Bleichroeder LP | 0 | $0 | 0.00% | −10,000−100.0% | Sold out |
| PSP Research LLC | 0 | $0 | 0.00% | −6,719−100.0% | Sold out |
| Blueshift Asset Management, LLC | 0 | $0 | 0.00% | −5,213−100.0% | Sold out |
| Ikarian Capital, LLC | 0 | $0 | 0.00% | −4,824−100.0% | Sold out |
| Graham Capital Management, L.P. | 0 | $0 | 0.00% | −4,778−100.0% | Sold out |
| Gabelli Funds LLC | 0 | $0 | 0.00% | −4,000−100.0% | Sold out |
| Merit Financial Group, LLC | 0 | $0 | 0.00% | −3,688−100.0% | Sold out |
| Northern Trust Corp | 0 | $0 | 0.00% | −3,645−100.0% | Sold out |
| Bank of New York Mellon Corp | 0 | $0 | 0.00% | −3,604−100.0% | Sold out |
| Profund Advisors LLC | 0 | $0 | 0.00% | −3,507−100.0% | Sold out |
| CIBC World Markets Inc. | 0 | $0 | 0.00% | −3,248−100.0% | Sold out |
| ProShare Advisors LLC | 0 | $0 | 0.00% | −2,957−100.0% | Sold out |
| Banque Cantonale Vaudoise | 0 | $0 | 0.00% | −2,945−100.0% | Sold out |
| Police & Firemen's Retirement System of New Jersey | 0 | $0 | 0.00% | −1,829−100.0% | Sold out |
| Country Trust Bank | 0 | $0 | 0.00% | −500−100.0% | Sold out |
| Private Wealth Management Group, LLC | 0 | $0 | 0.00% | −196−100.0% | Sold out |
| Daiwa Securities Group Inc. | 0 | $0 | 0.00% | −186−100.0% | Sold out |
| Northwestern Mutual Wealth Management Co | 0 | $0 | 0.00% | −60−100.0% | Sold out |
| Bessemer Group Inc | 0 | $0 | 0.00% | −29−100.0% | Sold out |
| Bellevue Asset Management, LLC | 0 | $0 | 0.00% | −15−100.0% | Sold out |
| Capitolis Liquid Global Markets LLC | – | – | – | – | Not filed |
| Janney Capital Management LLC | – | – | – | – | Not filed |