Structure Therapeutics Inc.
GPCR- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001888886
No open-market purchases or sales by Structure Therapeutics Inc. insiders were filed in the last 90 days; 191 institutions reported holding it in 13F filings for Q2 2026, worth $3.62B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Structure Therapeutics Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 199
- +44 vs. Q3 2025
- Shares held
- 65.8M
- +8.91M (+15.7%) vs. Q3 2025
- Total value
- $4.58B
- +$2.99B (+188.4%) vs. Q3 2025
- New holders
- 72
- 52 more added
- Sold out
- 28
- 63 more reduced
3 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting GPCR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 191 | $3.62B |
| Q1 2026 | 198 | $3.23B |
| Q4 2025 | 199 | $4.58B |
| Q3 2025 | 158 | $1.59B |
| Q2 2025 | 173 | $1.14B |
| Q1 2025 | 151 | $990.0M |
| Q4 2024 | 165 | $1.65B |
| Q3 2024 | 161 | $2.69B |
| Q2 2024 | 167 | $2.33B |
| Q1 2024 | 119 | $1.86B |
| Q4 2023 | 122 | $1.74B |
| Q3 2023 | 84 | $1.64B |
| Q2 2023 | 48 | $699.4M |
| Q1 2023 | 38 | $346.2M |
| Q4 2022 | 0 | $0 |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Structure Therapeutics Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Point72 Asset Management, L.P. | 0 | $0 | 0.00% | −407,700−100.0% | Sold out |
| Paradigm Biocapital Advisors LP | 0 | $0 | 0.00% | −372,869−100.0% | Sold out |
| Nantahala Capital Management, LLC | 0 | $0 | 0.00% | −368,553−100.0% | Sold out |
| Schroder Investment Management Group | 0 | $0 | 0.00% | −300,947−100.0% | Sold out |
| Two Sigma Advisers, LP | 0 | $0 | 0.00% | −249,299−100.0% | Sold out |
| Readystate Asset Management LP | 0 | $0 | 0.00% | −237,188−100.0% | Sold out |
| First Light Asset Management, LLC | 0 | $0 | 0.00% | −197,350−100.0% | Sold out |
| Handelsbanken Fonder AB | 0 | $0 | 0.00% | −168,000−100.0% | Sold out |
| Octagon Capital Advisors LP | 0 | $0 | 0.00% | −115,000−100.0% | Sold out |
| Jump Financial, LLC | 0 | $0 | 0.00% | −106,400−100.0% | Sold out |
| Macquarie Group Ltd | 0 | $0 | 0.00% | −58,000−100.0% | Sold out |
| Caption Management, LLC | 0 | $0 | 0.00% | −56,682−100.0% | Sold out |
| Boothbay Fund Management, LLC | 0 | $0 | 0.00% | −43,674−100.0% | Sold out |
| ADAR1 Capital Management, LLC | 0 | $0 | 0.00% | −15,200−100.0% | Sold out |
| CCG Wealth Management, LLC | 0 | $0 | 0.00% | −10,000−100.0% | Sold out |
| Gsa Capital Partners LLP | 0 | $0 | 0.00% | −9,886−100.0% | Sold out |
| Engineers Gate Manager LP | 0 | $0 | 0.00% | −9,593−100.0% | Sold out |
| Federated Hermes, Inc. | 0 | $0 | 0.00% | −4,500−100.0% | Sold out |
| FNY Investment Advisers, LLC | 0 | $0 | 0.00% | −1,700−100.0% | Sold out |
| Group One Trading, L.P. | 0 | $0 | 0.00% | −986−100.0% | Sold out |
| Legal & General Group Plc | 0 | $0 | 0.00% | −612−100.0% | Sold out |
| Harbour Investments, Inc. | 0 | $0 | 0.00% | −500−100.0% | Sold out |
| HighMark Wealth Management LLC | 0 | $0 | 0.00% | −418−100.0% | Sold out |
| Advisory Services Network, LLC | 0 | $0 | 0.00% | −110−100.0% | Sold out |
| Ameritas Advisory Services, LLC | 0 | $0 | 0.00% | −100−100.0% | Sold out |
| Washington Trust Advisors, Inc. | 0 | $0 | 0.00% | −41−100.0% | Sold out |
| Global Retirement Partners, LLC | 0 | $0 | 0.00% | −10−100.0% | Sold out |
| Point72 Europe (London) LLP | – | – | – | – | Not filed |
| Cubist Systematic Strategies, LLC | – | – | – | – | Not filed |
| Point72 Asia (Singapore) Pte. Ltd. | – | – | – | – | Not filed |