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89bio, Inc.

ETNBDelisted Oct 30, 2025
Industry
Pharmaceutical Preparations
SEC CIK
0001785173

89bio, Inc. was delisted on Oct 30, 2025; its insiders filed their last Form 4 on Nov 3, 2025; 198 institutions reported holding it in 13F filings for Q3 2025, worth $2.27B in total; no superinvestor held it.

13F holders, Q2 2024

Institutional positions in 89bio, Inc. as of Jun 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
145
−3 vs. Q1 2024
Shares held
103.4M
+5.08M (+5.2%) vs. Q1 2024
Total value
$828.4M
−$315.1M (−27.6%) vs. Q1 2024
New holders
20
66 more added
Sold out
23
43 more reduced

2 institutions that held it in Q1 2024 haven't filed for Q2 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ETNB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2024: 145 institutions
Q1 2021: 67 institutionsQ2 2021: 49 institutionsQ3 2021: 48 institutionsQ4 2021: 50 institutionsQ1 2022: 69 institutionsQ2 2022: 70 institutionsQ3 2022: 86 institutionsQ4 2022: 106 institutionsQ1 2023: 147 institutionsQ2 2023: 157 institutionsQ3 2023: 160 institutionsQ4 2023: 153 institutionsQ1 2024: 150 institutionsQ2 2024: 145 institutionsQ3 2024: 144 institutionsQ4 2024: 156 institutionsQ1 2025: 187 institutionsQ2 2025: 185 institutionsQ3 2025: 198 institutionsQ4 2025: 2 institutionsQ1 2026: 0 institutionsQ2 2026: 0 institutions
Value heldQ2 2024: $828.4M
Q1 2021: $400.6MQ2 2021: $315.2MQ3 2021: $339.4MQ4 2021: $226.1MQ1 2022: $64.3MQ2 2022: $104.6MQ3 2022: $227.3MQ4 2022: $589.5MQ1 2023: $1.08BQ2 2023: $1.46BQ3 2023: $1.11BQ4 2023: $1.05BQ1 2024: $1.14BQ2 2024: $828.4MQ3 2024: $773.8MQ4 2024: $948.7MQ1 2025: $1.14BQ2 2025: $1.58BQ3 2025: $2.27BQ4 2025: $1.11MQ1 2026: $0Q2 2026: $0
Institutions holding ETNB and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20260$0
Q4 20252$1.11M
Q3 2025198$2.27B
Q2 2025185$1.58B
Q1 2025187$1.14B
Q4 2024156$948.7M
Q3 2024144$773.8M
Q2 2024145$828.4M
Q1 2024150$1.14B
Q4 2023153$1.05B
Q3 2023160$1.11B
Q2 2023157$1.46B
Q1 2023147$1.08B
Q4 2022106$589.5M
Q3 202286$227.3M
Q2 202270$104.6M
Q1 202269$64.3M
Q4 202150$226.1M
Q3 202148$339.4M
Q2 202149$315.2M
Q1 202167$400.6M

Institutions, Q2 2024

Shares, value and share of portfolio for each institution holding 89bio, Inc.; share changes are against Q1 2024.

Institutions holding ETNB in Q2 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Newtyn Management, LLC240,000$1.92M0.36%−10,000−4.0%Reduced
Caption Management, LLC255,200$2.04M0.22%+114,216+81.0%Added
Renaissance Technologies LLC279,400$2.24M0.00%+279,400New
Nuveen Asset Management, LLC283,101$2.27M0.00%−267,493−48.6%Reduced
Morgan Stanley292,445$2.34M0.00%−520,177−64.0%Reduced
Bank of New York Mellon Corp299,689$2.40M0.00%+50,943+20.5%Added
Susquehanna International Group, LLP309,416$2.48M0.00%+129,454+71.9%Added
Bank of America Corp326,369$2.61M0.00%−82,270−20.1%Reduced
Wellington Management Group LLP357,536$2.86M0.00%+49,612+16.1%Added
Jane Street Group, LLC397,799$3.19M0.00%+282,377+244.6%Added
Adage Capital Partners GP, L.L.C.400,000$3.20M0.01%−50,000−11.1%Reduced
Integral Health Asset Management, LLC450,000$3.60M0.36%+150,000+50.0%Added
ExodusPoint Capital Management, LP459,230$3.68M0.04%+442,245+2,603.7%Added
Standard Life Aberdeen plc470,387$3.77M0.01%00.0%Unchanged
Sphera Funds Management Ltd.526,547$4.22M0.69%+10,665+2.1%Added
Two Sigma Investments, LP533,717$4.28M0.01%+287,617+116.9%Added
Alliancebernstein L.P.556,527$4.46M0.00%+325,520+140.9%Added
Charles Schwab Investment Management Inc667,118$5.34M0.00%+37,885+6.0%Added
Superstring Capital Management LP680,403$5.45M6.87%−260,884−27.7%Reduced
Erste Asset Management GmbH723,000$5.74M0.08%+50,000+7.4%Added
Northern Trust Corp723,864$5.80M0.00%+9,333+1.3%Added
University of Wisconsin Foundation724,132$5.80M6.53%+225,995+45.4%Added
Orchard Capital Managment, LLC739,208$5.92M1.79%−10,142−1.4%Reduced
Alyeska Investment Group, L.P.800,000$6.41M0.04%+500,000+166.7%Added
Franklin Resources Inc832,220$6.67M0.00%+4,563+0.6%Added
Candriam Luxembourg S.C.A.848,079$6.79M0.04%+538,079+173.6%Added
Goldman Sachs Group Inc904,817$7.25M0.00%+159,869+21.5%Added
Frazier Life Sciences Management, L.P.1,000,000$8.01M0.37%00.0%Unchanged
Millennium Management LLC1,010,352$8.09M0.01%−76,845−7.1%Reduced
MPM Oncology Impact Management LP1,121,736$8.99M1.40%+153,994+15.9%Added
Redmile Group, LLC1,745,656$14.0M0.85%−518,910−22.9%Reduced
Geode Capital Management, LLC1,914,614$15.3M0.00%+173,747+10.0%Added
Citadel Advisors LLC2,109,082$16.9M0.02%+539,540+34.4%Added
Laurion Capital Management LP2,180,931$17.5M0.57%−518,539−19.2%Reduced
Deep Track Capital, LP2,294,011$18.4M0.55%+2,294,011New
Westfield Capital Management Co LP2,319,365$18.6M0.09%+155,218+7.2%Added
State Street Corp3,244,503$26.0M0.00%−2,299,085−41.5%Reduced
Pictet Asset Management Holding SA3,602,585$28.9M0.03%−107,606−2.9%Reduced
Vanguard Group Inc4,804,953$38.5M0.00%+81,982+1.7%Added
BlackRock Inc.7,015,575$56.2M0.00%+377,591+5.7%Added
RTW Investments, LP7,378,548$59.1M0.92%00.0%Unchanged
BVF Inc7,568,479$60.6M1.70%+3,521,125+87.0%Added
Suvretta Capital Management, LLC8,031,845$64.3M2.63%+1,733,841+27.5%Added
Janus Henderson Group PLC13,276,110$106.3M0.06%+672,728+5.3%Added
Ra Capital Management, L.P.14,175,398$113.5M1.50%+1,408,450+11.0%Added
Holocene Advisors, LP0$00.00%−3,450,689−100.0%Sold out
Parkman Healthcare Partners LLC0$00.00%−179,899−100.0%Sold out
Capstone Investment Advisors, LLC0$00.00%−103,767−100.0%Sold out
Natixis0$00.00%−99,000−100.0%Sold out
1492 Capital Management LLC0$00.00%−79,168−100.0%Sold out
D. E. Shaw & Co., Inc.0$00.00%−55,493−100.0%Sold out
Tudor Investment Corp Et Al0$00.00%−47,630−100.0%Sold out
American International Group, Inc.0$00.00%−38,968−100.0%Sold out
UBS Oconnor LLC0$00.00%−35,962−100.0%Sold out
Corton Capital Inc.0$00.00%−29,452−100.0%Sold out
Sherbrooke Park Advisers LLC0$00.00%−29,002−100.0%Sold out
Entropy Technologies, LP0$00.00%−27,154−100.0%Sold out
Parkwood LLC0$00.00%−26,701−100.0%Sold out
E Fund Management Co., Ltd.0$00.00%−21,830−100.0%Sold out
Cubist Systematic Strategies, LLC0$00.00%−20,268−100.0%Sold out
Qube Research & Technologies Ltd0$00.00%−17,100−100.0%Sold out
Bridgefront Capital, LLC0$00.00%−14,261−100.0%Sold out
Dark Forest Capital Management LP0$00.00%−10,841−100.0%Sold out
Chicago Partners Investment Group LLC0$00.00%−10,084−100.0%Sold out
Metropolitan Life Insurance Co0$00.00%−4,178−100.0%Sold out
ICA Group Wealth Management, LLC0$00.00%−110−100.0%Sold out
Riggs Asset Managment Co. Inc.0$00.00%−31−100.0%Sold out
Nelson, Van Denburg & Campbell Wealth Management Group, LLC0$00.00%−12−100.0%Sold out
Credit Suisse AG––––Not filed
Oracle Alpha Inc.––––Not filed