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89bio, Inc.

ETNBDelisted Oct 30, 2025
Industry
Pharmaceutical Preparations
SEC CIK
0001785173

89bio, Inc. was delisted on Oct 30, 2025; its insiders filed their last Form 4 on Nov 3, 2025; 198 institutions reported holding it in 13F filings for Q3 2025, worth $2.27B in total; no superinvestor held it.

13F holders, Q1 2024

Institutional positions in 89bio, Inc. as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
150
−3 vs. Q4 2023
Shares held
98.4M
+4.22M (+4.5%) vs. Q4 2023
Total value
$1.14B
+$92.6M (+8.8%) vs. Q4 2023
New holders
22
69 more added
Sold out
25
52 more reduced

Compare with Q4 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ETNB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2024: 150 institutions
Q1 2021: 67 institutionsQ2 2021: 49 institutionsQ3 2021: 48 institutionsQ4 2021: 50 institutionsQ1 2022: 69 institutionsQ2 2022: 70 institutionsQ3 2022: 86 institutionsQ4 2022: 106 institutionsQ1 2023: 147 institutionsQ2 2023: 157 institutionsQ3 2023: 160 institutionsQ4 2023: 153 institutionsQ1 2024: 150 institutionsQ2 2024: 145 institutionsQ3 2024: 144 institutionsQ4 2024: 156 institutionsQ1 2025: 187 institutionsQ2 2025: 185 institutionsQ3 2025: 198 institutionsQ4 2025: 2 institutionsQ1 2026: 0 institutionsQ2 2026: 0 institutions
Value heldQ1 2024: $1.14B
Q1 2021: $400.6MQ2 2021: $315.2MQ3 2021: $339.4MQ4 2021: $226.1MQ1 2022: $64.3MQ2 2022: $104.6MQ3 2022: $227.3MQ4 2022: $589.5MQ1 2023: $1.08BQ2 2023: $1.46BQ3 2023: $1.11BQ4 2023: $1.05BQ1 2024: $1.14BQ2 2024: $828.4MQ3 2024: $773.8MQ4 2024: $948.7MQ1 2025: $1.14BQ2 2025: $1.58BQ3 2025: $2.27BQ4 2025: $1.11MQ1 2026: $0Q2 2026: $0
Institutions holding ETNB and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20260$0
Q4 20252$1.11M
Q3 2025198$2.27B
Q2 2025185$1.58B
Q1 2025187$1.14B
Q4 2024156$948.7M
Q3 2024144$773.8M
Q2 2024145$828.4M
Q1 2024150$1.14B
Q4 2023153$1.05B
Q3 2023160$1.11B
Q2 2023157$1.46B
Q1 2023147$1.08B
Q4 2022106$589.5M
Q3 202286$227.3M
Q2 202270$104.6M
Q1 202269$64.3M
Q4 202150$226.1M
Q3 202148$339.4M
Q2 202149$315.2M
Q1 202167$400.6M

Institutions, Q1 2024

Shares, value and share of portfolio for each institution holding 89bio, Inc.; share changes are against Q4 2023.

Institutions holding ETNB in Q1 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Two Sigma Advisers, LP143,500$1.67M0.00%−23,800−14.2%Reduced
Swiss National Bank147,200$1.71M0.00%+4,400+3.1%Added
Comerica Bank171,000$1.99M0.01%+15,070+9.7%Added
Parkman Healthcare Partners LLC179,899$2.09M0.26%−39,549−18.0%Reduced
Susquehanna International Group, LLP179,962$2.09M0.00%+13,752+8.3%Added
Alliancebernstein L.P.231,007$2.69M0.00%−67,982−22.7%Reduced
Two Sigma Investments, LP246,100$2.86M0.01%+117,342+91.1%Added
Bank of New York Mellon Corp248,746$2.90M0.00%+26,326+11.8%Added
Newtyn Management, LLC250,000$2.91M0.58%−22,500−8.3%Reduced
Alyeska Investment Group, L.P.300,000$3.49M0.02%−283,187−48.6%Reduced
Integral Health Asset Management, LLC300,000$3.49M0.34%+300,000New
Wellington Management Group LLP307,924$3.58M0.00%+68,897+28.8%Added
Candriam Luxembourg S.C.A.310,000$3.61M0.02%+30,000+10.7%Added
UBS Group AG320,732$3.73M0.00%+36,235+12.7%Added
Barclays PLC354,088$4.12M0.00%−189,464−34.9%Reduced
Bank of America Corp408,639$4.76M0.00%+136,740+50.3%Added
Citigroup Inc418,259$4.87M0.01%+203,657+94.9%Added
Adage Capital Partners GP, L.L.C.450,000$5.24M0.01%−2,675,000−85.6%Reduced
Rafferty Asset Management, LLC461,952$5.38M0.02%+8,278+1.8%Added
Standard Life Aberdeen plc470,387$5.48M0.01%+256,195+119.6%Added
University of Wisconsin Foundation498,137$5.80M6.54%+371,621+293.7%Added
Sphera Funds Management Ltd.515,882$6.00M0.97%+107,208+26.2%Added
Nuveen Asset Management, LLC550,594$6.41M0.00%+308,205+127.2%Added
Eagle Asset Management Inc679,767$7.29M0.04%−22,328−3.2%Reduced
Charles Schwab Investment Management Inc629,233$7.32M0.00%+129,880+26.0%Added
Erste Asset Management GmbH673,000$7.80M0.11%+170,000+33.8%Added
Northern Trust Corp714,531$8.32M0.00%+96,530+15.6%Added
Goldman Sachs Group Inc744,948$8.67M0.00%+113,836+18.0%Added
Orchard Capital Managment, LLC749,350$8.72M2.56%+10,142+1.4%Added
Morgan Stanley812,622$9.46M0.00%−676,638−45.4%Reduced
Franklin Resources Inc827,657$9.63M0.00%−460.0%Reduced
Superstring Capital Management LP941,287$11.0M7.24%−80,190−7.9%Reduced
MPM Oncology Impact Management LP967,742$11.3M1.81%+967,742New
Frazier Life Sciences Management, L.P.1,000,000$11.6M0.49%−1,000,000−50.0%Reduced
Millennium Management LLC1,087,197$12.7M0.01%+528,312+94.5%Added
Citadel Advisors LLC1,569,542$18.3M0.02%−608,797−27.9%Reduced
Geode Capital Management, LLC1,740,867$20.3M0.00%+363,157+26.4%Added
Westfield Capital Management Co LP2,164,147$25.2M0.13%+402,999+22.9%Added
Redmile Group, LLC2,264,566$26.4M0.97%+295,164+15.0%Added
Laurion Capital Management LP2,699,470$31.4M0.87%−4,732−0.2%Reduced
Holocene Advisors, LP3,450,689$40.2M0.15%−39,939−1.1%Reduced
Pictet Asset Management Holding SA3,710,191$43.2M0.05%−847,489−18.6%Reduced
BVF Inc4,047,354$47.1M1.30%00.0%Unchanged
Vanguard Group Inc4,722,971$55.0M0.00%+415,386+9.6%Added
State Street Corp5,543,588$64.5M0.00%+144,230+2.7%Added
Suvretta Capital Management, LLC6,298,004$73.3M3.09%+1,409,570+28.8%Added
BlackRock Inc.6,637,984$77.3M0.00%+1,183,788+21.7%Added
RTW Investments, LP7,378,548$85.9M1.27%+1,799,617+32.3%Added
Janus Henderson Group PLC12,603,382$146.6M0.08%+3,688,241+41.4%Added
Ra Capital Management, L.P.12,766,948$148.6M1.89%+1,350,000+11.8%Added
Federated Hermes, Inc.0$00.00%−1,962,566−100.0%Sold out
Marshall Wace, LLP0$00.00%−554,337−100.0%Sold out
StemPoint Capital LP0$00.00%−408,257−100.0%Sold out
Weiss Multi-Strategy Advisers LLC0$00.00%−230,000−100.0%Sold out
Monashee Investment Management LLC0$00.00%−140,000−100.0%Sold out
Twinbeech Capital LP0$00.00%−86,689−100.0%Sold out
HRT Financial LP0$00.00%−65,192−100.0%Sold out
Skandinaviska Enskilda Banken AB (publ)0$00.00%−39,400−100.0%Sold out
Walleye Capital LLC0$00.00%−30,193−100.0%Sold out
SG Americas Securities, LLC0$00.00%−28,319−100.0%Sold out
Nebula Research & Development LLC0$00.00%−18,559−100.0%Sold out
State Board of Administration of Florida Retirement System0$00.00%−17,700−100.0%Sold out
Pekin Hardy Strauss, Inc.0$00.00%−14,385−100.0%Sold out
Walleye Trading LLC0$00.00%−12,261−100.0%Sold out
BIT Capital GmbH0$00.00%−11,127−100.0%Sold out
Atom Investors LP0$00.00%−10,970−100.0%Sold out
Cinctive Capital Management LP0$00.00%−10,000−100.0%Sold out
Aquatic Capital Management LLC0$00.00%−5,500−100.0%Sold out
Simplex Trading, LLC0$00.00%−5,133−100.0%Sold out
EntryPoint Capital, LLC0$00.00%−4,039−100.0%Sold out
AJOVista, LLC0$00.00%−3,789−100.0%Sold out
FNY Investment Advisers, LLC0$00.00%−2,000−100.0%Sold out
Cape Investment Advisory, Inc.0$00.00%−615−100.0%Sold out
Greenwood Gearhart Inc0$00.00%−577−100.0%Sold out
Quadrant Capital Group LLC0$00.00%−204−100.0%Sold out