C4 Therapeutics, Inc.
CCCC- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001662579
No open-market purchases or sales by C4 Therapeutics, Inc. insiders were filed in the last 90 days; 147 institutions reported holding it in 13F filings for Q2 2026, worth $547.6M in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in C4 Therapeutics, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 123
- +23 vs. Q4 2025
- Shares held
- 84.5M
- +9.04M (+12.0%) vs. Q4 2025
- Total value
- $221.3M
- +$77.2M (+53.6%) vs. Q4 2025
- New holders
- 34
- 41 more added
- Sold out
- 11
- 30 more reduced
1 institution that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting CCCC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 147 | $547.6M |
| Q1 2026 | 123 | $221.3M |
| Q4 2025 | 101 | $152.5M |
| Q3 2025 | 97 | $116.6M |
| Q2 2025 | 102 | $78.2M |
| Q1 2025 | 115 | $102.6M |
| Q4 2024 | 113 | $231.8M |
| Q3 2024 | 118 | $365.9M |
| Q2 2024 | 115 | $281.3M |
| Q1 2024 | 106 | $475.6M |
| Q4 2023 | 92 | $265.6M |
| Q3 2023 | 84 | $64.5M |
| Q2 2023 | 100 | $94.1M |
| Q1 2023 | 121 | $117.5M |
| Q4 2022 | 117 | $231.4M |
| Q3 2022 | 114 | $345.9M |
| Q2 2022 | 113 | $297.2M |
| Q1 2022 | 125 | $904.8M |
| Q4 2021 | 119 | $1.15B |
| Q3 2021 | 113 | $1.54B |
| Q2 2021 | 107 | $1.21B |
| Q1 2021 | 83 | $926.8M |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding C4 Therapeutics, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Morgan Stanley | 9,072,400 | $23.9M | 0.00% | +90,738+1.0% | Added |
| Ra Capital Management, L.P. | 8,000,000 | $21.0M | 0.22% | 00.0% | Unchanged |
| Bain Capital Life Sciences Investors, LLC | 7,171,910 | $18.9M | 1.70% | 00.0% | Unchanged |
| Lynx1 Capital Management LP | 6,998,902 | $18.4M | 2.91% | −99,231−1.4% | Reduced |
| Vanguard Capital Management LLC | 3,861,852 | $10.2M | 0.00% | +3,861,852 | New |
| Soleus Capital Management, L.P. | 3,803,942 | $10.0M | 0.41% | 00.0% | Unchanged |
| Two Sigma Investments, LP | 3,035,634 | $7.98M | 0.01% | +1,526,031+101.1% | Added |
| Wasatch Advisors Inc | 2,961,761 | $7.79M | 0.05% | −1,383,157−31.8% | Reduced |
| JPMorgan Chase & Co | 3,223,054 | $7.57M | 0.00% | +3,217,109+54,114.5% | Added |
| Citadel Advisors LLC | 2,511,015 | $6.60M | 0.00% | +2,063,207+460.7% | Added |
| Renaissance Technologies LLC | 2,461,815 | $6.47M | 0.01% | +859,235+53.6% | Added |
| Goldman Sachs Group Inc | 2,387,378 | $6.28M | 0.00% | +1,298,358+119.2% | Added |
| Bank of America Corp | 2,359,241 | $6.20M | 0.00% | −28,345−1.2% | Reduced |
| Squadron Capital Management LLC | 2,250,000 | $5.92M | 2.37% | +2,250,000 | New |
| BlackRock, Inc. | 2,048,526 | $5.39M | 0.00% | +78,712+4.0% | Added |
| Silverarc Capital Management, LLC | 1,911,785 | $5.03M | 0.59% | −82,439−4.1% | Reduced |
| Acadian Asset Management LLC | 1,890,914 | $4.97M | 0.01% | +1,233,741+187.7% | Added |
| Millennium Management LLC | 1,393,342 | $3.66M | 0.00% | +204,373+17.2% | Added |
| Susquehanna International Group, LLP | 1,286,840 | $3.38M | 0.00% | −488,943−27.5% | Reduced |
| Jane Street Group, LLC | 1,246,896 | $3.28M | 0.00% | +372,102+42.5% | Added |
| D. E. Shaw & Co., Inc. | 1,060,331 | $2.79M | 0.00% | +1,007,452+1,905.2% | Added |
| Geode Capital Management, LLC | 951,043 | $2.50M | 0.00% | −37,835−3.8% | Reduced |
| Wells Fargo & Company | 867,911 | $2.28M | 0.00% | +58,651+7.2% | Added |
| OrbiMed Advisors LLC | 856,353 | $2.25M | 0.05% | −548,549−39.0% | Reduced |
| Congress Asset Management Co | 830,624 | $2.18M | 0.02% | +830,624 | New |
| Qube Research & Technologies Ltd | 752,114 | $1.98M | 0.00% | +461,880+159.1% | Added |
| Vanguard Fiduciary Trust Co | 484,131 | $1.27M | 0.00% | +484,131 | New |
| StemPoint Capital LP | 453,236 | $1.19M | 0.23% | +453,236 | New |
| Charles Schwab Investment Management Inc | 452,228 | $1.19M | 0.00% | +2,796+0.6% | Added |
| Dimensional Fund Advisors LP | 442,518 | $1.16M | 0.00% | +146,038+49.3% | Added |
| Platinum Investment Management Ltd | 384,766 | $1.01M | 0.26% | +384,766 | New |
| State Street Corp | 382,973 | $1.01M | 0.00% | +40,200+11.7% | Added |
| Barclays PLC | 317,877 | $836.0K | 0.00% | +98,673+45.0% | Added |
| 683 Capital Management, LLC | 300,000 | $789.0K | 0.07% | −100,000−25.0% | Reduced |
| Connor, Clark & Lunn Investment Management Ltd. | 277,183 | $729.0K | 0.00% | +239,462+634.8% | Added |
| FMR LLC | 272,368 | $716.3K | 0.00% | +17,962+7.1% | Added |
| Jacobs Levy Equity Management, Inc | 264,620 | $696.0K | 0.00% | +264,620 | New |
| Susquehanna Portfolio Strategies, LLC | 260,279 | $684.5K | 0.01% | −11,774−4.3% | Reduced |
| Man Group plc | 256,468 | $674.5K | 0.00% | +100,370+64.3% | Added |
| LPL Financial LLC | 246,800 | $649.1K | 0.00% | +3,495+1.4% | Added |
| Invesco Ltd. | 244,507 | $643.1K | 0.00% | −23,843−8.9% | Reduced |
| Walleye Capital LLC | 239,118 | $628.9K | 0.00% | −204,223−46.1% | Reduced |
| Hennion & Walsh Asset Management, Inc. | 223,168 | $586.9K | 0.02% | −13,969−5.9% | Reduced |
| UBS Group AG | 215,877 | $567.8K | 0.00% | +163,125+309.2% | Added |
| BNP Paribas Arbitrage, SA | 190,348 | $500.6K | 0.00% | +188,187+8,708.3% | Added |
| Northern Trust Corp | 189,479 | $498.3K | 0.00% | +23,272+14.0% | Added |
| Toronto Dominion Bank | 174,663 | $459.4K | 0.00% | +174,663 | New |
| Point72 Asset Management, L.P. | 169,096 | $444.7K | 0.00% | −9,270,232−98.2% | Reduced |
| HRT Financial LP | 162,930 | $428.0K | 0.00% | +162,930 | New |
| Marshall Wace, LLP | 155,495 | $409.0K | 0.00% | −109,532−41.3% | Reduced |
| Atom Investors LP | 136,047 | $357.8K | 0.03% | +31,083+29.6% | Added |
| Canada Pension Plan Investment Board | 135,600 | $356.6K | 0.00% | +106,100+359.7% | Added |
| Bridgeway Capital Management, LLC | 131,100 | $344.8K | 0.01% | 00.0% | Unchanged |
| Hudson Bay Capital Management LP | 130,081 | $342.1K | 0.00% | +18,530+16.6% | Added |
| Mariner, LLC | 127,517 | $334.2K | 0.00% | −533−0.4% | Reduced |
| Verdad Advisers, LP | 109,407 | $287.7K | 0.32% | +109,407 | New |
| Brevan Howard Capital Management LP | 92,647 | $243.7K | 0.00% | +92,647 | New |
| Panagora Asset Management Inc | 86,760 | $228.2K | 0.00% | +86,760 | New |
| Axq Capital, LP | 86,278 | $226.9K | 0.03% | +86,278 | New |
| American Century Companies Inc | 85,444 | $224.7K | 0.00% | +17,199+25.2% | Added |
| Vienna Powszechne Towarzystwo Emerytalne S.A. Vienna Insurance Group | 85,000 | $223.6K | 0.09% | 00.0% | Unchanged |
| Price T Rowe Associates Inc | 71,546 | $189.0K | 0.00% | +59,146+477.0% | Added |
| Crestwood Advisors Group LLC | 66,536 | $175.0K | 0.00% | 00.0% | Unchanged |
| Quadrature Capital Ltd | 62,760 | $165.1K | 0.00% | −70,352−52.9% | Reduced |
| Jain Global LLC | 62,390 | $164.1K | 0.00% | +49,628+388.9% | Added |
| Intrepid Family Office LLC | 60,000 | $157.8K | 0.14% | +5,000+9.1% | Added |
| Omers Administration Corp | 59,700 | $157.0K | 0.00% | −58,000−49.3% | Reduced |
| Seven Fleet Capital Management LP | 57,076 | $150.1K | 0.05% | +57,076 | New |
| Readystate Asset Management LP | 49,586 | $130.4K | 0.01% | +49,586 | New |
| ExodusPoint Capital Management, LP | 47,507 | $124.9K | 0.00% | −14,658−23.6% | Reduced |
| XTX Topco Ltd | 47,151 | $124.0K | 0.00% | −57,307−54.9% | Reduced |
| ADAR1 Capital Management, LLC | 43,000 | $113.1K | 0.01% | +43,000 | New |
| Citigroup Inc | 42,428 | $111.6K | 0.00% | −7,412−14.9% | Reduced |
| Squarepoint Ops LLC | 40,664 | $106.9K | 0.00% | −95,390−70.1% | Reduced |
| Colony Group, LLC | 38,187 | $100.4K | 0.00% | 00.0% | Unchanged |
| Diametric Capital, LP | 34,594 | $91.0K | 0.02% | +34,594 | New |
| Vanguard Global Advisers, LLC | 33,832 | $89.0K | 0.00% | +33,832 | New |
| Prelude Capital Management, LLC | 30,957 | $81.4K | 0.01% | +30,957 | New |
| Farallon Capital Management, L.L.C. | 28,000 | $73.6K | 0.00% | 00.0% | Unchanged |
| Jefferies Financial Group Inc. | 26,120 | $68.7K | 0.00% | −9,220−26.1% | Reduced |
| Catalyst Funds Management Pty Ltd | 25,740 | $67.7K | 0.01% | −16,760−39.4% | Reduced |
| SEI Investments Co | 25,134 | $66.1K | 0.00% | +25,134 | New |
| Cresset Asset Management, LLC | 25,000 | $65.8K | 0.00% | 00.0% | Unchanged |
| Winton Group Ltd | 24,700 | $65.0K | 0.00% | +24,700 | New |
| Schonfeld Strategic Advisors LLC | 23,944 | $63.0K | 0.00% | +23,944 | New |
| Graham Capital Management, L.P. | 23,733 | $62.4K | 0.00% | −78,465−76.8% | Reduced |
| CI Private Wealth, LLC | 21,387 | $56.2K | 0.00% | 00.0% | Unchanged |
| Callan Family Office, LLC | 19,146 | $50.4K | 0.00% | −12,597−39.7% | Reduced |
| China Universal Asset Management Co., Ltd. | 17,316 | $45.5K | 0.00% | +1,524+9.7% | Added |
| Prudential Financial Inc | 15,950 | $41.9K | 0.00% | +900+6.0% | Added |
| JustInvest LLC | 15,249 | $40.1K | 0.00% | +25+0.2% | Added |
| Dauntless Investment Group, LLC | 15,000 | $39.5K | 0.11% | +15,000 | New |
| Ewa, LLC | 14,572 | $38.3K | 0.01% | −2,317−13.7% | Reduced |
| Nine Masts Capital Ltd | 14,157 | $37.2K | 0.01% | +2,685+23.4% | Added |
| HSBC Holdings PLC | 13,629 | $36.0K | 0.00% | 00.0% | Unchanged |
| Northern Lights Advisors, Inc. | 12,930 | $34.0K | 0.02% | 00.0% | Unchanged |
| CTC Alternative Strategies, Ltd. | 10,792 | $28.4K | 0.06% | +10,792 | New |
| SummitTX Capital, L.P. | 10,466 | $27.5K | 0.00% | +10,466 | New |
| Two Sigma Securities, LLC | 10,203 | $26.8K | 0.00% | +10,203 | New |
| Simplicity Wealth,LLC | 10,201 | $26.8K | 0.00% | −10.0% | Reduced |